Iiris Hovatta

Iiris Hovatta

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Iiris Hovatta

Iiris Hovatta

Publications by authors named "Iiris Hovatta"

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Immunomodulatory effects of antipsychotic treatment on gene expression in first-episode psychosis.

J Psychiatr Res 2019 Feb 10;109:18-26. Epub 2018 Nov 10.

Mental Health Unit, National Institute for Health and Welfare, P.O. Box 30, FI-00271, Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jpsychires.2018.11.008DOI Listing
February 2019

Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction.

Neuropsychopharmacology 2019 Feb 15. Epub 2019 Feb 15.

Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/s41386-019-0344-5DOI Listing
February 2019

Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies.

Am J Clin Nutr 2018 09;108(3):453-475

Departments of Complex Genetics.

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https://academic.oup.com/ajcn/article/108/3/453/5095489
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http://dx.doi.org/10.1093/ajcn/nqy107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454526PMC
September 2018

Brain activation induced by chronic psychosocial stress in mice.

Sci Rep 2017 11 8;7(1):15061. Epub 2017 Nov 8.

Department of Biosciences, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/s41598-017-15422-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678090PMC
November 2017

Assessing the contributions of childhood maltreatment subtypes and depression case-control status on telomere length reveals a specific role of physical neglect.

J Affect Disord 2017 Apr 3;213:16-22. Epub 2017 Feb 3.

King's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2017.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191534PMC
April 2017

A genome-wide screen for acrophobia susceptibility loci in a Finnish isolate.

Sci Rep 2016 12 20;6:39345. Epub 2016 Dec 20.

Department of Biosciences, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/srep39345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171840PMC
December 2016

Longitudinal decline of leukocyte telomere length in old age and the association with sex and genetic risk.

Aging (Albany NY) 2016 07;8(7):1398-415

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.18632/aging.100995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993338PMC
July 2016

Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe.

Cell Rep 2015 Oct 1;13(2):350-64. Epub 2015 Oct 1.

Department of Biosciences, University of Helsinki, Helsinki 00790, Finland; Institute of Biotechnology, University of Helsinki, Helsinki 00790, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247150099
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http://dx.doi.org/10.1016/j.celrep.2015.08.081DOI Listing
October 2015

The transcriptional landscape of age in human peripheral blood.

Authors:
Marjolein J Peters Roby Joehanes Luke C Pilling Claudia Schurmann Karen N Conneely Joseph Powell Eva Reinmaa George L Sutphin Alexandra Zhernakova Katharina Schramm Yana A Wilson Sayuko Kobes Taru Tukiainen Yolande F Ramos Harald H H Göring Myriam Fornage Yongmei Liu Sina A Gharib Barbara E Stranger Philip L De Jager Abraham Aviv Daniel Levy Joanne M Murabito Peter J Munson Tianxiao Huan Albert Hofman André G Uitterlinden Fernando Rivadeneira Jeroen van Rooij Lisette Stolk Linda Broer Michael M P J Verbiest Mila Jhamai Pascal Arp Andres Metspalu Liina Tserel Lili Milani Nilesh J Samani Pärt Peterson Silva Kasela Veryan Codd Annette Peters Cavin K Ward-Caviness Christian Herder Melanie Waldenberger Michael Roden Paula Singmann Sonja Zeilinger Thomas Illig Georg Homuth Hans-Jörgen Grabe Henry Völzke Leif Steil Thomas Kocher Anna Murray David Melzer Hanieh Yaghootkar Stefania Bandinelli Eric K Moses Jack W Kent Joanne E Curran Matthew P Johnson Sarah Williams-Blangero Harm-Jan Westra Allan F McRae Jennifer A Smith Sharon L R Kardia Iiris Hovatta Markus Perola Samuli Ripatti Veikko Salomaa Anjali K Henders Nicholas G Martin Alicia K Smith Divya Mehta Elisabeth B Binder K Maria Nylocks Elizabeth M Kennedy Torsten Klengel Jingzhong Ding Astrid M Suchy-Dicey Daniel A Enquobahrie Jennifer Brody Jerome I Rotter Yii-Der I Chen Jeanine Houwing-Duistermaat Margreet Kloppenburg P Eline Slagboom Quinta Helmer Wouter den Hollander Shannon Bean Towfique Raj Noman Bakhshi Qiao Ping Wang Lisa J Oyston Bruce M Psaty Russell P Tracy Grant W Montgomery Stephen T Turner John Blangero Ingrid Meulenbelt Kerry J Ressler Jian Yang Lude Franke Johannes Kettunen Peter M Visscher G Gregory Neely Ron Korstanje Robert L Hanson Holger Prokisch Luigi Ferrucci Tonu Esko Alexander Teumer Joyce B J van Meurs Andrew D Johnson

Nat Commun 2015 Oct 22;6:8570. Epub 2015 Oct 22.

The National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts 01702, USA.

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http://dx.doi.org/10.1038/ncomms9570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639797PMC
October 2015

Genetics: dynamic cellular aging markers associated with major depression.

Authors:
Iiris Hovatta

Curr Biol 2015 May;25(10):R409-11

Department of Biosciences, University of Helsinki, Helsinki, Finland and Department of Health, National Institute for Health and Welfare, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.03.036DOI Listing
May 2015

Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation.

PLoS One 2014 27;9(2):e89321. Epub 2014 Feb 27.

Folkhälsan Institute of Genetics, Helsinki, Finland ; Department of Medical Genetics, Haartman Institute and Research Programs Unit, Molecular Neurology, University of Helsinki, Helsinki, Finland ; Neuroscience Center, University of Helsinki, Helsinki, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089321PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937333PMC
October 2014

Allele-specific regulation of DISC1 expression by miR-135b-5p.

Eur J Hum Genet 2014 Jun 30;22(6):840-3. Epub 2013 Oct 30.

1] Institute for Molecular Medicine, Finland (FIMM), University of Helsinki, Helsinki, Finland [2] Department of Biosciences, Viikki Biocenter, University of Helsinki, Helsinki, Finland [3] Research Programs Unit, Biomedicum-Helsinki, and Department of Medical Genetics, Haartman Institute, University of Helsinki, Helsinki, Finland [4] Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland.

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http://dx.doi.org/10.1038/ejhg.2013.246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023220PMC
June 2014

Longer telomere length in patients with schizophrenia.

Schizophr Res 2013 Sep 17;149(1-3):116-20. Epub 2013 Jul 17.

Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, J 5, 68159 Mannheim, Germany.

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http://dx.doi.org/10.1016/j.schres.2013.06.043DOI Listing
September 2013

Anxiety genetics - findings from cross-species genome-wide approaches.

Biol Mood Anxiety Disord 2013 May 9;3(1). Epub 2013 May 9.

Department of Biosciences, Viikki Biocenter, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1186/2045-5380-3-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655048PMC
May 2013

Identification of seven loci affecting mean telomere length and their association with disease.

Authors:
Veryan Codd Christopher P Nelson Eva Albrecht Massimo Mangino Joris Deelen Jessica L Buxton Jouke Jan Hottenga Krista Fischer Tõnu Esko Ida Surakka Linda Broer Dale R Nyholt Irene Mateo Leach Perttu Salo Sara Hägg Mary K Matthews Jutta Palmen Giuseppe D Norata Paul F O'Reilly Danish Saleheen Najaf Amin Anthony J Balmforth Marian Beekman Rudolf A de Boer Stefan Böhringer Peter S Braund Paul R Burton Anton J M de Craen Matthew Denniff Yanbin Dong Konstantinos Douroudis Elena Dubinina Johan G Eriksson Katia Garlaschelli Dehuang Guo Anna-Liisa Hartikainen Anjali K Henders Jeanine J Houwing-Duistermaat Laura Kananen Lennart C Karssen Johannes Kettunen Norman Klopp Vasiliki Lagou Elisabeth M van Leeuwen Pamela A Madden Reedik Mägi Patrik K E Magnusson Satu Männistö Mark I McCarthy Sarah E Medland Evelin Mihailov Grant W Montgomery Ben A Oostra Aarno Palotie Annette Peters Helen Pollard Anneli Pouta Inga Prokopenko Samuli Ripatti Veikko Salomaa H Eka D Suchiman Ana M Valdes Niek Verweij Ana Viñuela Xiaoling Wang H-Erich Wichmann Elisabeth Widen Gonneke Willemsen Margaret J Wright Kai Xia Xiangjun Xiao Dirk J van Veldhuisen Alberico L Catapano Martin D Tobin Alistair S Hall Alexandra I F Blakemore Wiek H van Gilst Haidong Zhu Jeanette Erdmann Muredach P Reilly Sekar Kathiresan Heribert Schunkert Philippa J Talmud Nancy L Pedersen Markus Perola Willem Ouwehand Jaakko Kaprio Nicholas G Martin Cornelia M van Duijn Iiris Hovatta Christian Gieger Andres Metspalu Dorret I Boomsma Marjo-Riitta Jarvelin P Eline Slagboom John R Thompson Tim D Spector Pim van der Harst Nilesh J Samani

Nat Genet 2013 Apr;45(4):422-7, 427e1-2

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.

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http://www.ideal-ageing.eu/uploads/publicaties/2013_codd_nat
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http://www.nature.com/doifinder/10.1038/ng.2528
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http://dx.doi.org/10.1038/ng.2528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006270PMC
April 2013

Support for involvement of glutamate decarboxylase 1 and neuropeptide Y in anxiety susceptibility.

Am J Med Genet B Neuropsychiatr Genet 2012 Apr 10;159B(3):316-27. Epub 2012 Feb 10.

Research Programs Unit, Molecular Neurology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/ajmg.b.32029DOI Listing
April 2012

Translational neuroscience of schizophrenia: seeking a meeting of minds between mouse and man.

Sci Transl Med 2011 Sep;3(102):102mr3

Department of Neuroscience and Pharmacology, University Medical Center Utrecht, 3584CG Utrecht, The Netherlands.

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http://dx.doi.org/10.1126/scitranslmed.3002917DOI Listing
September 2011

Novel role of RGS2 in regulation of antioxidant homeostasis in neuronal cells.

FEBS Lett 2011 May 16;585(9):1375-81. Epub 2011 Apr 16.

Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, USA.

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http://doi.wiley.com/10.1016/j.febslet.2011.04.023
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http://dx.doi.org/10.1016/j.febslet.2011.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108258PMC
May 2011

Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways.

Biol Psychiatry 2011 Mar 17;69(6):526-33. Epub 2010 Dec 17.

Genes and Disease Program, Centre for Genomic Regulation (CRG), Public Health and Epidemiology Network Biomedical Research Center (CIBERESP), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.biopsych.2010.10.010DOI Listing
March 2011

Oxidative stress in anxiety and comorbid disorders.

Neurosci Res 2010 Dec 9;68(4):261-75. Epub 2010 Sep 9.

Research Program of Molecular Neurology, Faculty of Medicine, University of Helsinki, Finland.

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http://dx.doi.org/10.1016/j.neures.2010.08.007DOI Listing
December 2010

No evidence for shorter leukocyte telomere length in Parkinson's disease patients.

J Gerontol A Biol Sci Med Sci 2010 Nov 16;65(11):1181-4. Epub 2010 Jul 16.

Research Program of Molecular Neurology, Biomedicum Helsinki, University of Helsinki, Haartmaninkatu 8, FIN-00290 Helsinki, Finland.

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http://dx.doi.org/10.1093/gerona/glq125DOI Listing
November 2010

Mitochondrial myopathy induces a starvation-like response.

Hum Mol Genet 2010 Oct 23;19(20):3948-58. Epub 2010 Jul 23.

Research Program of Molecular Neurology, Biomedicum-Helsinki, 00290 Helsinki, Finland.

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http://dx.doi.org/10.1093/hmg/ddq310DOI Listing
October 2010

An association analysis of circadian genes in anxiety disorders.

Biol Psychiatry 2010 Jun 1;67(12):1163-70. Epub 2010 Feb 1.

Research Program of Molecular Neurology, University of Helsinki, Helsinki, Finland.

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https://linkinghub.elsevier.com/retrieve/pii/S00063223090144
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http://dx.doi.org/10.1016/j.biopsych.2009.12.011DOI Listing
June 2010

The effects of globin on microarray-based gene expression analysis of mouse blood.

Mamm Genome 2010 Jun 16;21(5-6):268-75. Epub 2010 May 16.

Graduate Program in Biomedical Sciences, Department of Medicine, University of California at San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1007/s00335-010-9261-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890980PMC
June 2010

Molecular genetics of anxiety in mice and men.

Ann Med 2008 ;40(2):92-109

Research Program of Molecular Neurology, Biomedicum, University of Helsinki, Finland.

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http://dx.doi.org/10.1080/07853890701747096DOI Listing
June 2008

[Not Available].

Authors:
Iiris Hovatta

Duodecim 2007 ;123(14):1665-6

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April 2008

No association between common variants in glyoxalase 1 and autism spectrum disorders.

Am J Med Genet B Neuropsychiatr Genet 2008 Jan;147B(1):124-7

Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland. karola.

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http://dx.doi.org/10.1002/ajmg.b.30582DOI Listing
January 2008

Batten disease (JNCL) is linked to disturbances in mitochondrial, cytoskeletal, and synaptic compartments.

J Neurosci Res 2006 Oct;84(5):1124-38

Department of Molecular Medicine, National Public Health Institute, Biomedicum Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/jnr.21015DOI Listing
October 2006

Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice.

Nature 2005 Dec 23;438(7068):662-6. Epub 2005 Oct 23.

The Salk Institute for Biological Studies, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature04250DOI Listing
December 2005

Clinical phenotype of schizophrenia in a Finnish isolate.

Schizophr Res 2004 Apr;67(2-3):195-205

Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, Helsinki 00300, Finland.

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http://dx.doi.org/10.1016/S0920-9964(03)00007-0DOI Listing
April 2004

Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse.

J Neurosci 2002 Jan;22(2):471-7

Molecular Neurogenetics Laboratory, Department of Neurochemistry, Max-Planck-Institute for Brain Research, D-60528 Frankfurt, Germany.

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January 2002