Igor Yakushev

Igor Yakushev

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Igor Yakushev

Igor Yakushev

Publications by authors named "Igor Yakushev"

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57Publications

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Reduced blood oxygenation level dependent connectivity is related to hypoperfusion in Alzheimer's disease.

J Cereb Blood Flow Metab 2019 Jul 12;39(7):1314-1325. Epub 2018 Feb 12.

1 Department of Diagnostic and Interventional Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1177/0271678X18759182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668525PMC
July 2019

Associations of Neprilysin Activity in CSF with Biomarkers for Alzheimer's Disease.

Neurodegener Dis 2019 2;19(1):43-50. Epub 2019 Jul 2.

Dementia Research Group, School of Clinical Sciences, University of Bristol, Southmead Hospital, Bristol, United Kingdom.

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http://dx.doi.org/10.1159/000500811DOI Listing
July 2019

Rate of β-amyloid accumulation varies with baseline amyloid burden: Implications for anti-amyloid drug trials.

Alzheimers Dement 2018 11 4;14(11):1387-1396. Epub 2018 Jul 4.

Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; Neuroimaging Center (TUM-NIC), Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S15525260183021
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http://dx.doi.org/10.1016/j.jalz.2018.05.013DOI Listing
November 2018

Correction: F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases.

Mol Psychiatry 2018 Nov 21. Epub 2018 Nov 21.

Department of Nuclear Medicine, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1038/s41380-018-0302-3DOI Listing
November 2018

Reply: Neurometabolic Resting-State Networks Derived from Seed-Based Functional Connectivity Analysis.

J Nucl Med 2018 10 2;59(10):1643. Epub 2018 Aug 2.

Technische Universität München Einsteinstrasse 1 München, D-81675, Germany E-mail:

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http://dx.doi.org/10.2967/jnumed.118.216150DOI Listing
October 2018

Plasma levels of soluble amyloid precursor protein β in symptomatic Alzheimer's disease.

Eur Arch Psychiatry Clin Neurosci 2018 Aug 10;268(5):519-524. Epub 2017 Jun 10.

Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://dx.doi.org/10.1007/s00406-017-0815-9DOI Listing
August 2018

F-FIBT may expand PET for β-amyloid imaging in neurodegenerative diseases.

Mol Psychiatry 2018 Aug 17. Epub 2018 Aug 17.

Department of Nuclear Medicine, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://www.nature.com/articles/s41380-018-0203-5
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http://dx.doi.org/10.1038/s41380-018-0203-5DOI Listing
August 2018

Potential Effect of Prolonged Sevoflurane Anesthesia on the Kinetics of [C]Raclopride in Non-human Primates.

Mol Imaging Biol 2018 04;20(2):183-187

Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s11307-017-1120-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862918PMC
April 2018

Increasing Diagnostic Accuracy of Mild Cognitive Impairment due to Alzheimer's Disease by User-Independent, Web-Based Whole-Brain Volumetry.

J Alzheimers Dis 2018 ;65(4):1459-1467

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.3233/JAD-180532DOI Listing
January 2018

Metabolic connectivity: methods and applications.

Curr Opin Neurol 2017 Dec;30(6):677-685

aDepartment of Nuclear Medicine bNeuroimaging Center (TUM-NIC), Klinikum rechts der Isar, Technische Universität München, Munich cDepartment of Nuclear Medicine, Universität zu Köln, Cologne, Germany dCognitive Neuroscience Division, Department of Neurology, Columbia University, New York City, New York, USA.

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http://dx.doi.org/10.1097/WCO.0000000000000494DOI Listing
December 2017

Resting-State Networks as Simultaneously Measured with Functional MRI and PET.

J Nucl Med 2017 08 2;58(8):1314-1317. Epub 2017 Mar 2.

Department of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany

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http://dx.doi.org/10.2967/jnumed.116.185835DOI Listing
August 2017

Predicting Regional Pattern of Longitudinal β-Amyloid Accumulation by Baseline PET.

J Nucl Med 2017 04 6;58(4):639-645. Epub 2016 Oct 6.

Department of Nuclear Medicine, University of Munich, Munich, Germany.

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http://dx.doi.org/10.2967/jnumed.116.176115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373505PMC
April 2017

Pypes: Workflows for Processing Multimodal Neuroimaging Data.

Front Neuroinform 2017 11;11:25. Epub 2017 Apr 11.

Department of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universität MünchenMunich, Germany.

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http://dx.doi.org/10.3389/fninf.2017.00025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387693PMC
April 2017

Metabolic connectivity for differential diagnosis of dementing disorders.

J Cereb Blood Flow Metab 2017 01 31;37(1):252-262. Epub 2015 Dec 31.

Department of Nuclear Medicine, Technische Universität München, Munich, Germany

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http://dx.doi.org/10.1177/0271678X15622465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363743PMC
January 2017

Neuro-cognitive mechanisms of simultanagnosia in patients with posterior cortical atrophy.

Brain 2016 12 3;139(Pt 12):3267-3280. Epub 2016 Oct 3.

1 General and Experimental Psychology, Department of Psychology, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://brain.oxfordjournals.org/content/brain/139/12/3267.fu
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http://dx.doi.org/10.1093/brain/aww235DOI Listing
December 2016

Conflicting cerebrospinal fluid biomarkers and progression to dementia due to Alzheimer's disease.

Alzheimers Res Ther 2016 12 9;8(1):51. Epub 2016 Dec 9.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, München, Germany.

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http://dx.doi.org/10.1186/s13195-016-0220-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146856PMC
December 2016

Comparison between MRI-based attenuation correction methods for brain PET in dementia patients.

Eur J Nucl Med Mol Imaging 2016 Nov 20;43(12):2190-2200. Epub 2016 Apr 20.

Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00259-016-3394-5DOI Listing
November 2016

Mapping CSF biomarker profiles onto NIA-AA guidelines for Alzheimer's disease.

Eur Arch Psychiatry Clin Neurosci 2016 Oct 8;266(7):587-97. Epub 2015 Aug 8.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1007/s00406-015-0628-7DOI Listing
October 2016

Metabolic connectivity as index of verbal working memory.

J Cereb Blood Flow Metab 2015 Jul 18;35(7):1122-6. Epub 2015 Mar 18.

1] Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany [2] Department of Nuclear Medicine, Technische Universität München, Munich, Germany [3] Neuroimaging Center (TUM-NIC), Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1038/jcbfm.2015.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640275PMC
July 2015

The lower hippocampus global connectivity, the higher its local metabolism in Alzheimer disease.

Neurology 2015 May 15;84(19):1956-63. Epub 2015 Apr 15.

From the Departments of Neuroradiology (M.T., L.P., M. Scherr, C.M., S.M.B., V.R., C.S.), Nuclear Medicine (M.T., S.F., K.S., I.Y., M. Schwaiger, V.R., C.S., A.D.), and Psychiatry and Psychotherapy (M. Scherr, T.G., J.D.-S., C.S.) of Klinikum rechts der Isar, Technische Universität München; TUM-NIC Neuroimaging Center (M.T., L.P., M. Scherr, C.M., S.F., S.M.B., I.Y., V.R., C.S.), Technische Universität München, Munich; Graduate School of Systemic Neurosciences (C.M., S.M.B.), Ludwig Maximilians University, Munich; Department of Nuclear Medicine (M.T., A.D.), University Hospital of Cologne, Germany; Sleep Disorders Research Center (M.T.), Kermanshah University of Medical Sciences, Iran; and Department of Neurology (M. Scherr), Christian Doppler Clinic, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1212/WNL.0000000000001575DOI Listing
May 2015

Prefrontal hypometabolism in Alzheimer disease is related to longitudinal amyloid accumulation in remote brain regions.

J Nucl Med 2015 Mar 12;56(3):399-404. Epub 2015 Feb 12.

Department of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany Technische Universität München Neuroimaging Center (TUM-NIC), Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.2967/jnumed.114.149302DOI Listing
March 2015

Limited agreement between biomarkers of neuronal injury at different stages of Alzheimer's disease.

Alzheimers Dement 2014 Nov 22;10(6):684-9. Epub 2014 May 22.

Department of Nuclear Medicine, Technische Universität München, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2014.03.006DOI Listing
November 2014

In Alzheimer's disease, hypometabolism in low-amyloid brain regions may be a functional consequence of pathologies in connected brain regions.

Brain Connect 2014 Jun;4(5):371-83

1 Department of Nuclear Medicine, Klinikum Rechts der Isar, Technische Universität München , Munich, Germany .

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http://dx.doi.org/10.1089/brain.2013.0212DOI Listing
June 2014

Structural integrity of the corpus callosum predicts long-term transfer of fluid intelligence-related training gains in normal aging.

Hum Brain Mapp 2014 Jan 11;35(1):309-18. Epub 2012 Sep 11.

Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, Mainz, Germany.

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http://doi.wiley.com/10.1002/hbm.22177
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http://dx.doi.org/10.1002/hbm.22177DOI Listing
January 2014

Task- versus amphetamine-induced displacement of high-affinity D2/3 receptor ligands.

J Nucl Med 2013 Oct 18;54(10):1849. Epub 2013 Jun 18.

Department of Nuclear Medicine Klinikum rechts der Isar Technische Universität München Ismaninger Strasse 2281675 Munich, Germany E-mail:

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http://dx.doi.org/10.2967/jnumed.112.117564DOI Listing
October 2013

Cognitive reserve impacts on inter-individual variability in resting-state cerebral metabolism in normal aging.

Neuroimage 2012 Nov 13;63(2):713-22. Epub 2012 Jul 13.

Cyclotron Research Centre, University of Liège, Allée du 6 Août, 8, B30, 4000 Liège, Belgium.

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http://dx.doi.org/10.1016/j.neuroimage.2012.06.074DOI Listing
November 2012

Automated tractography of the cingulate bundle in Alzheimer's disease: a multicenter DTI study.

J Magn Reson Imaging 2012 Jul 22;36(1):84-91. Epub 2012 Feb 22.

Department of Psychiatry, University Medical Center of Mainz, Mainz, Germany.

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http://dx.doi.org/10.1002/jmri.23621DOI Listing
July 2012

Diffusion tensor imaging of the hippocampus in MCI and early Alzheimer's disease.

J Alzheimers Dis 2011 ;26 Suppl 3:257-62

Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany.

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http://dx.doi.org/10.3233/JAD-2011-0001DOI Listing
February 2012

Stage-dependent agreement between cerebrospinal fluid proteins and FDG-PET findings in Alzheimer's disease.

Curr Alzheimer Res 2012 Feb;9(2):241-7

Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Germany.

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February 2012

Functional implications of hippocampal degeneration in early Alzheimer's disease: a combined DTI and PET study.

Eur J Nucl Med Mol Imaging 2011 Dec 27;38(12):2219-27. Epub 2011 Jul 27.

Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany.

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http://dx.doi.org/10.1007/s00259-011-1882-1DOI Listing
December 2011

Basilar artery diameter is a potential screening tool for Fabry disease in young stroke patients.

Cerebrovasc Dis 2011 22;31(3):294-9. Epub 2010 Dec 22.

Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, Mainz, Germany.

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http://dx.doi.org/10.1159/000322558DOI Listing
June 2011

Horizontal versus longitudinal axis of the hippocampus: metabolic differentiation as measured with high-resolution PET/MRI.

J Nucl Med 2011 Feb 13;52(2):329; author reply 329-30. Epub 2011 Jan 13.

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http://dx.doi.org/10.2967/jnumed.110.085084DOI Listing
February 2011

Cerebrospinal fluid tau protein levels and 18F-fluorodeoxyglucose positron emission tomography in the differential diagnosis of Alzheimer's disease.

Dement Geriatr Cogn Disord 2010 15;30(3):245-53. Epub 2010 Sep 15.

Department of Psychiatry and Psychotherapy, University Medical Center Mainz, Mainz, Germany.

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http://dx.doi.org/10.1159/000320206DOI Listing
January 2011

Human dopamine receptor D2/D3 availability predicts amygdala reactivity to unpleasant stimuli.

Hum Brain Mapp 2010 May;31(5):716-26

Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1002/hbm.20900DOI Listing
May 2010

Tiagabine does not attenuate alcohol-induced activation of the human reward system.

Psychopharmacology (Berl) 2007 May 30;191(4):975-83. Epub 2007 Jan 30.

Department of Psychiatry, University of Mainz, Untere Zahlbacher Strasse 8, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00213-006-0696-5DOI Listing
May 2007