Ignasi Sahun

Ignasi Sahun

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Ignasi Sahun

Ignasi Sahun

Publications by authors named "Ignasi Sahun"

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Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome.

Neurobiol Dis 2019 07 1;127:210-222. Epub 2019 Mar 1.

Instituto de Biología Molecular de Barcelona (IBMB), CSIC, 08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.02.022DOI Listing
July 2019

Intracisternal Gtf2i Gene Therapy Ameliorates Deficits in Cognition and Synaptic Plasticity of a Mouse Model of Williams-Beuren Syndrome.

Mol Ther 2015 Nov 28;23(11):1691-1699. Epub 2015 Jul 28.

Neurosciences Program, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Unitat de Genètica, Barcelona, Spain; Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), ISCIII, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15250016163018
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http://dx.doi.org/10.1038/mt.2015.130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817950PMC
November 2015

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

PLoS Genet 2015 Mar 24;11(3):e1005062. Epub 2015 Mar 24.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France; Université de Strasbourg, Illkirch, France; Institut Clinique de la Souris, PHENOMIN, GIE CERBM, Illkirch, France.

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http://dx.doi.org/10.1371/journal.pgen.1005062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372517PMC
March 2015

Heterozygous deletion of the Williams-Beuren syndrome critical interval in mice recapitulates most features of the human disorder.

Hum Mol Genet 2014 Dec 15;23(24):6481-94. Epub 2014 Jul 15.

Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), ISCIII, Spain, Neurosciences Program, Institut Hospital del Mar D'Investigacions Mèdiques (IMIM), Barcelona 08003, Spain,

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http://dx.doi.org/10.1093/hmg/ddu368DOI Listing
December 2014

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.

Neurobiol Dis 2014 Sep 4;69:65-75. Epub 2014 May 4.

Univ Paris Diderot, Sorbonne Paris Cité, Adaptive Functional Biology, UMR CNRS 8251, 75205 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.04.016DOI Listing
September 2014

Cognition and hippocampal plasticity in the mouse is altered by monosomy of a genomic region implicated in Down syndrome.

Genetics 2014 Jul 21;197(3):899-912. Epub 2014 Apr 21.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, 67404 Illkirch, France Centre National de la Recherche Scientifique, UMR7104, Illkirch, France Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France Université de Strasbourg, 67400 Illkirch, France Institut Clinique de la Souris, PHENOMIN, Groupement d'Intérêt Economique Centre Européen de Recherche en Biologie Moléculaire, 67404 Illkirch, France

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http://dx.doi.org/10.1534/genetics.114.165241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096369PMC
July 2014

Carnitine palmitoyltransferase 1C deficiency causes motor impairment and hypoactivity.

Behav Brain Res 2013 Nov 21;256:291-7. Epub 2013 Aug 21.

Department of Basic Sciences, Facultat de Medicina i Ciències de la Salut, Universitat Internacional de Catalunya (UIC), 08195 Sant Cugat del Vallés, Spain; Centro de Investigación Biomédica en Red (CIBER)-Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.

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http://dx.doi.org/10.1016/j.bbr.2013.08.004DOI Listing
November 2013

AGC1-malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway.

J Neurochem 2013 Feb;124(3):347-62

Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa UAM-CSIC, and CIBER de Enfermedades Raras (CIBERER), Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1111/jnc.12096DOI Listing
February 2013

Reduced Mid1 Expression and Delayed Neuromotor Development in daDREAM Transgenic Mice.

Front Mol Neurosci 2012 3;5:58. Epub 2012 May 3.

Genomic Regulation Center, Parc de Recerca Biomèdica de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Raras Barcelona, Spain.

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http://dx.doi.org/10.3389/fnmol.2012.00058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342529PMC
October 2012

Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition.

J Biol Chem 2012 Jun 26;287(25):21224-32. Epub 2012 Apr 26.

From the Department of Basic Sciences, Facultat de Medicina i Ciències de la Salut, Universitat Internacional de Catalunya, E-08195 Sant Cugat del Vallès, Spain.

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http://dx.doi.org/10.1074/jbc.M111.337493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375544PMC
June 2012

Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.

Neuropsychopharmacology 2011 Nov 3;36(12):2395-405. Epub 2011 Aug 3.

Developmental Neurobiology and Regeneration Unit, Institute for Research in Biomedicine, Parc Cientific de Barcelona, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/npp.2011.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194085PMC
November 2011

An animal model of compulsive food-taking behaviour.

Addict Biol 2009 Sep;14(4):373-83

Medimod Pharmacology Services GmbH, Germany.

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http://dx.doi.org/10.1111/j.1369-1600.2009.00175.xDOI Listing
September 2009

Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.

Am J Hum Genet 2008 Oct;83(4):479-88

Programa Gens i Malaltia. Centre de Regulació Genòmica-CRG, UPF, Parc de Recerca Biomèdica de Barcelona-PRBB, Barcelona 08003, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297080050
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http://dx.doi.org/10.1016/j.ajhg.2008.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561933PMC
October 2008

Dissociation between CA3-CA1 synaptic plasticity and associative learning in TgNTRK3 transgenic mice.

J Neurosci 2007 Feb;27(9):2253-60

Genes and Disease Program, Genomic Regulation Center, Universidad Pompeu Fabra, Barcelona Biomedical Research Park, 08003 Barcelona, Spain.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.4055-06.2
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http://dx.doi.org/10.1523/JNEUROSCI.4055-06.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673497PMC
February 2007