Ignacio Wistuba

Ignacio Wistuba

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Ignacio Wistuba

Ignacio Wistuba

Publications by authors named "Ignacio Wistuba"

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Multiplex Immunofluorescence Assays.

Methods Mol Biol 2020 ;2055:467-495

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1007/978-1-4939-9773-2_22DOI Listing
January 2020

Tumor cellular proliferation is associated with enhanced immune checkpoint expression in stage I non-small cell lung cancer.

J Thorac Cardiovasc Surg 2019 Sep 17;158(3):911-919.e6. Epub 2019 May 17.

Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2019.04.084DOI Listing
September 2019

Non-invasive genotyping of metastatic colorectal cancer using circulating cell free DNA.

Cancer Genet 2019 Sep 12;237:82-89. Epub 2019 Jun 12.

Department of Translational Molecular Pathology, Division of Pathology and Laboratory Medicine, The University of Texas M.D. Anderson Cancer Center, 6565 MD Anderson Blvd., Houston, TX 77030, United States; Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2019.06.004DOI Listing
September 2019

Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer.

Oncogene 2019 Sep 9. Epub 2019 Sep 9.

Quantitative Biomedical Research Center, Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1038/s41388-019-1000-6DOI Listing
September 2019

Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer.

Cancer Res 2019 Aug 25;79(16):4211-4226. Epub 2019 Jun 25.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-3803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697620PMC
August 2019

Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy.

Cancer Cell 2019 Aug 18;36(2):168-178.e4. Epub 2019 Jul 18.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Institute of Biomedical Sciences and Center for Molecular Medicine, China Medical University, Taichung 404, Taiwan; Department of Biotechnology, Asia University, Taichung 413, Taiwan; Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.06.008DOI Listing
August 2019

Development and Application of Duplex Sequencing Strategy for Cell-Free DNA-Based Longitudinal Monitoring of Stage IV Colorectal Cancer.

J Mol Diagn 2019 Aug 8. Epub 2019 Aug 8.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2019.06.008DOI Listing
August 2019

Rational "Error Elimination" Approach to Evaluating Molecular Barcoded Next-Generation Sequencing Data Identifies Low-Frequency Mutations in Hematologic Malignancies.

J Mol Diagn 2019 May 20;21(3):471-482. Epub 2019 Feb 20.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2019.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521894PMC
May 2019

Development and Validation of a Pathology Image Analysis-based Predictive Model for Lung Adenocarcinoma Prognosis - A Multi-cohort Study.

Sci Rep 2019 May 3;9(1):6886. Epub 2019 May 3.

Quantitative Biomedical Research Center, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA.

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http://dx.doi.org/10.1038/s41598-019-42845-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499884PMC
May 2019

LCE: an open web portal to explore gene expression and clinical associations in lung cancer.

Oncogene 2019 04 7;38(14):2551-2564. Epub 2018 Dec 7.

Quantitative Biomedical Research Center, Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1038/s41388-018-0588-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477796PMC
April 2019

Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung.

EBioMedicine 2019 Apr 21;42:296-303. Epub 2019 Mar 21.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491940PMC
April 2019

PI3-kinase pathway biomarkers in oral cancer and tumor immune cells.

Head Neck 2019 Mar 16;41(3):615-622. Epub 2018 Dec 16.

The University of Texas MD Anderson Cancer Center, Department of Thoracic/Head and Neck Medical Oncology.

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http://dx.doi.org/10.1002/hed.25350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382518PMC
March 2019

Centrifuged supernatants from FNA provide a liquid biopsy option for clinical next-generation sequencing of thyroid nodules.

Cancer Cytopathol 2019 Mar 8;127(3):146-160. Epub 2019 Jan 8.

Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncy.22098DOI Listing
March 2019

State-of-the-Art of Profiling Immune Contexture in the Era of Multiplexed Staining and Digital Analysis to Study Paraffin Tumor Tissues.

Cancers (Basel) 2019 Feb 20;11(2). Epub 2019 Feb 20.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, 2130 West Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/cancers11020247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406364PMC
February 2019

Development and Validation of a Predictive Radiomics Model for Clinical Outcomes in Stage I Non-small Cell Lung Cancer.

Int J Radiat Oncol Biol Phys 2018 11 15;102(4):1090-1097. Epub 2017 Nov 15.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2017.10.046DOI Listing
November 2018

Reply to Oegema et al.: CFI-400945 and Polo-like kinase 4 inhibition.

Proc Natl Acad Sci U S A 2018 11 30;115(46):E10810-E10811. Epub 2018 Oct 30.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.

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http://dx.doi.org/10.1073/pnas.1813967115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243257PMC
November 2018

Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration.

iScience 2018 Nov 2;9:451-460. Epub 2018 Nov 2.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249353PMC
November 2018

Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.

J Clin Oncol 2018 08 15;36(23):2386-2394. Epub 2018 Jun 15.

M. Catherine Pietanza, Lee M. Krug, Mark G. Kris, and Charles M. Rudin, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College; Kaitlin M. Woo, Yevgeniva Bensman, Brenda Hurtado, and Martin Fleisher, Memorial Sloan Kettering Cancer Center, New York, NY; Saiama N. Waqar, Washington University School of Medicine in St. Louis, St Louis, MO; Afshin Dowlati, Case Western Reserve University and University Hospitals Seidman Cancer Center, Cleveland, OH; Christine L. Hann, Johns Hopkins University, Baltimore; Alice Chen, National Institutes of Health, Bethesda, MD; Alberto Chiappori, H. Lee Moffitt Cancer Center, Tampa, FL; Taofeek K. Owonikoko, Emory University, Atlanta, GA; and Robert J. Cardnell, Junya Fujimoto, Lihong Long, Lixia Diao, Jing Wang, Patricia de Groot, Erik P. Sulman, Ignacio I. Wistuba, John V. Heymach, and Lauren Averett Byers, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2018.77.7672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085179PMC
August 2018

Salvaging the supernatant: next generation cytopathology for solid tumor mutation profiling.

Mod Pathol 2018 07 20;31(7):1036-1045. Epub 2018 Feb 20.

Department of Hematopathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://www.nature.com/articles/s41379-018-0006-x
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http://dx.doi.org/10.1038/s41379-018-0006-xDOI Listing
July 2018

Mutations and PD-1 Inhibitor Resistance in -Mutant Lung Adenocarcinoma.

Cancer Discov 2018 07 17;8(7):822-835. Epub 2018 May 17.

Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-18-0099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030433PMC
July 2018

LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer.

Oncotarget 2018 Jul 3;9(51):29601-29618. Epub 2018 Jul 3.

Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas, USA.

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http://dx.doi.org/10.18632/oncotarget.25642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049873PMC
July 2018

Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints are Co-expressed in Non-Small Cell Lung Carcinoma Tumors.

J Thorac Oncol 2018 06 8;13(6):779-791. Epub 2018 Mar 8.

Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.03.002DOI Listing
June 2018

Major pathologic response and RAD51 predict survival in lung cancer patients receiving neoadjuvant chemotherapy.

Cancer Med 2018 06 19;7(6):2405-2414. Epub 2018 Apr 19.

Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cam4.1505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010873PMC
June 2018

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma.

J Clin Oncol 2018 05 12;36(14):1419-1427. Epub 2018 Feb 12.

Frederick F. Lang, Charles Conrad, Candelaria Gomez-Manzano, W.K. Alfred Yung, Raymond Sawaya, Jeffrey S. Weinberg, Sujit S. Prabhu, Ganesh Rao, Gregory N. Fuller, Kenneth D. Aldape, Joy Gumin, Luis M. Vence, Ignacio Wistuba, Jaime Rodriguez-Canales, Pamela A. Villalobos, and Juan Fueyo, The University of Texas MD Anderson Cancer Center; Brett Ewald, Joanna J. Peterkin, and Frank Tufaro, DNAtrix, Houston, TX; Clemens M.F. Dirven, Erasmus University Medical Center, Rotterdam, the Netherlands; and Sonia Tejada, Ricardo D. Valle, and Marta M. Alonso, Clínica Universidad de Navarra, Pamplona, Spain.

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http://ascopubs.org/doi/10.1200/JCO.2017.75.8219
Publisher Site
http://dx.doi.org/10.1200/JCO.2017.75.8219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075856PMC
May 2018

Spatial interaction of tumor cells and regulatory T cells correlates with survival in non-small cell lung cancer.

Lung Cancer 2018 03 4;117:73-79. Epub 2018 Feb 4.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA; Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center,1515 Holcombe Boulevard, Houston, TX, 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294443PMC
March 2018

Induction Cisplatin Docetaxel Followed by Surgery and Erlotinib in Non-Small Cell Lung Cancer.

Ann Thorac Surg 2018 Feb 6;105(2):418-424. Epub 2017 Dec 6.

Department of Thoracic Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2017.08.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783769PMC
February 2018

Biomarker-Integrated Neoadjuvant Dasatinib Trial in Resectable Malignant Pleural Mesothelioma.

J Thorac Oncol 2018 02 5;13(2):246-257. Epub 2017 Dec 5.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1016/j.jtho.2017.10.033DOI Listing
February 2018

Novel enriched pathways in superficial malignant peripheral nerve sheath tumours and spindle/desmoplastic melanomas.

J Pathol 2018 01;244(1):97-106

Department of Pathology, Section of Dermatopathology, the University of Texas - MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1002/path.4996DOI Listing
January 2018

RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non-small Cell Lung Cancer.

Clin Cancer Res 2018 01 13;24(2):341-350. Epub 2017 Oct 13.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1455DOI Listing
January 2018

Programmed Death Cell Ligand 1 (PD-L1) Is Associated With Survival in Stage I Non-Small Cell Lung Cancer.

Semin Thorac Cardiovasc Surg 2017 Autumn;29(3):408-415. Epub 2017 May 26.

MD Anderson Cancer Center, Department of Translational Molecular Pathology, Houston, Texas.

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http://dx.doi.org/10.1053/j.semtcvs.2017.05.008DOI Listing
December 2017

Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis.

Lung Cancer 2017 10 5;112:47-56. Epub 2017 Aug 5.

Reproductive & Developmental Biology Laboratory, National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718380PMC
October 2017