Publications by authors named "Ignacio Romero"

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Biological Effects of Temsirolimus on the mTOR Pathway in Endometrial Carcinoma: A Pharmacodynamic Phase II Study.
Int J Gynecol Cancer 2016 Jun 2. Epub 2016 Jun 2.
*Hospital Universitari Arnau de Vilanova, Universitat de Lleida, IRBLleida, Lleida; †Hospital Clínico Universitario Clínico San Carlos, Madrid; ‡Fundación Instituto Valenciano de Oncología, Valencia; §Hospital Universitari Valle dHebron, Barcelona; ∥Foundation MD Anderson Cancer Centre Madrid, and Department of Biochemistry, Universidad Autonoma de Madrid (UAM), Instituto de Investigaciones Biomedicas "Alberto Sols" (CSIC-UAM), IdiPAZ, Madrid; and ¶MedSIR ARO, Barcelona, Spain.

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain Barrier.
Int J Mol Sci 2016 Jun 9;17(6). Epub 2016 Jun 9.
Department of Microbiology and Immunology, and Center for Molecular Virology and Translational Neuroscience, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, PA 19102, USA.


Early alterations of Hedgehog signaling pathway in vascular endothelial cells after peripheral nerve injury elicit blood-nerve barrier disruption, nerve inflammation, and neuropathic pain development.
Pain 2016 Apr;157(4):827-39
aUFR d'Odontologie, Université Paris Descartes, Hôpital Bretonneau, Paris, France bCentre de Psychiatrie et Neurosciences, INSERM U894, Université Paris Descartes, Hôpital Sainte-Anne, Paris, France cUniversité Paris Descartes, Institut Cochin, Paris, France dDepartment of Biological Sciences, The Open University, Walton Hall, Milton Keynes, United Kingdom eWeill Medical College of Cornell University, New York, NY, USA fUFR d'Odontologie, Université Paris Diderot, Hôpital Pitié Salpêtrière, Paris, France.



Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors.
Mol Brain 2015 Aug 22;8:51. Epub 2015 Aug 22.
Sheffield Institute for Translational Neuroscience, Department of Neuroscience, The University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.

Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood-brain barrier.
J Gen Virol 2015 Jul 23;96(Pt 7):1682-95. Epub 2015 Feb 23.
1Clermont Université, Université d'Auvergne, EPIE, EA 4843, Clermont-Ferrand, France 2CHU Clermont-Ferrand, Service de Virologie, Clermont-Ferrand, France.


The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family.
AAPS J 2014 Nov 26;16(6):1247-58. Epub 2014 Aug 26.
Institute for Clinical Pharmacology, University Medical Center Göttingen, Georg-August University, Robert-Koch-Str. 40, 37075, Göttingen, Germany.

Two-port laparoscopic radical cystectomy with reusable umbilical system: a feasibility study.
Urology 2014 Nov 24;84(5):1088-93. Epub 2014 Oct 24.
Servicio de Urología, Hospital Universitario de Getafe, Madrid, Spain; Departamento Clínico, Facultad de Ciencias Biomédicas, Universidad Europea de Madrid, Laureate International Universities, Madrid, Spain.


Nanoparticle formulation improves the anticonvulsant effect of clonazepam on the pentylenetetrazole-induced seizures: behavior and electroencephalogram.
J Pharm Sci 2014 Aug 10;103(8):2509-19. Epub 2014 Jun 10.
Laboratorio de Investigación y Posgrado en Tecnología Farmacéutica, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Estado de México, 54740, México; Laboratory of Connective Tissue, Centro Nacional de Investigación y Atención de Quemados, Instituto Nacional de Rehabilitación, México, D.F., México; Section des Sciences Pharmaceutiques, Technologie Pharmaceutique, Université de Genève, Geneva, 41211, Switzerland.

MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
FASEB J 2014 Jun 6;28(6):2551-65. Epub 2014 Mar 6.
Department of Life, Health, and Chemical Sciences, Biomedical Research Network, The Open University, Milton Keynes, UK;

Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?
BMC Neurosci 2014 Apr 23;15:51. Epub 2014 Apr 23.
Department of Pharmaceutical Sciences, Texas Tech University Health Sciences Center, School of Pharmacy, 1300 S, Coulter Street, Amarillo TX 79106, USA.

Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles.
Analyst 2014 Mar 5;139(5):923-30. Epub 2013 Nov 5.
Centre for BioNano Interactions, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.

A recombinant inhibitory isoform of vascular endothelial growth factor164/165 aggravates ischemic brain damage in a mouse model of focal cerebral ischemia.
Am J Pathol 2013 Sep 30;183(3):1010-24. Epub 2013 Jul 30.
Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, Louisiana 71130, USA.

MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis.
J Neurosci 2013 Apr;33(16):6857-63
Blood-Brain Barrier Research Group, Molecular Cell Biology and Immunology, Neuroscience Campus Amsterdam, VU University Medical Center, 1007 MB Amsterdam, The Netherlands.

The angiogenic gene profile of circulating endothelial progenitor cells from ischemic stroke patients.
Vasc Cell 2013 Feb 6;5(1). Epub 2013 Feb 6.
Neurovascular Research Laboratory and Neurovascular Unit, Neurology and Medicine Department, Universitat Autònoma de Barcelona, Vall d'Hebron Research Institute of Vall d'Hebron Hospital, Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.


Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications.
Proc Natl Acad Sci U S A 2013 Jan 31;110(3):832-41. Epub 2012 Dec 31.
William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, United Kingdom.

Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging.
FASEB J 2012 Oct 22;26(10):3969-79. Epub 2012 Jun 22.
Platform: Production de Protéines Recombinantes et d’Anticorps-Proteopole, Unité Genes, Synapses, et Cognition, Centre National de la Recherche Scientifique (CNRS), Institut Pasteur, 25 Rue du Dr Roux, 75724 Paris cedex 15, France.

Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells.
Part Fibre Toxicol 2012 Jul 3;9:23. Epub 2012 Jul 3.
REPAIR-lab, Institute of Pathology, University Medical Center of the Johannes Gutenberg University, Langenbeckstraße 1, Mainz, 55101, Germany.


Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro.
J Neuroinflammation 2011 Nov 23;8:162. Epub 2011 Nov 23.
Department of Molecular and Cellular Physiology, School of Graduate Studies, Louisiana State University Health Sciences Center-Shreveport, 1501 Kings Hwy, Shreveport, LA 71130, USA.

Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models.
J Neurosci Methods 2011 Aug 14;199(2):223-9. Epub 2011 May 14.
Cellular & Molecular Neuro-oncology Research Group, Cellular and Molecular Medicine Division, Institute of Biomedical & Biomolecular Sciences, School of Pharmacy & Biomedical Sciences, University of Portsmouth, St Michael's Building, White Swan Road, Portsmouth PO1 2DT, UK.

Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells.
J Cereb Blood Flow Metab 2009 Dec 5;29(12):1933-45. Epub 2009 Aug 5.
Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS.
Sci Rep 2013 ;3:1687
Key Laboratory of Protein and Peptide Pharmaceuticals, CAS-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China.

Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C.
PLoS One 2014 4;9(2):e88154. Epub 2014 Feb 4.
Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Hannover, Germany ; Center for Systems Neuroscience, Hannover, Germany.




Malignant Bowel Obstruction in Relapsed Ovarian Cancer With Peritoneal Carcinomatosis: An Occlusive State.
Int J Gynecol Cancer 2017 09;27(7):1367-1372
*Gynecology Department and †Area Clínica de Oncología Ginecológica, Fundación Instituto Valenciano de Oncología, Valencia, Spain; ‡Gynecology Department, Sanatorio Allende, Córdoba, Argentine; and §Palliative Care Department, ∥Emergency Unit Department, and ¶Medical Oncology Department, Instituto Valenciano de Oncología, Valencia, Spain.


[Recommendations for biomarker testing in epithelial ovarian cancer. A national consensus statement by the Spanish Society of Pathology and the Spanish Society of Medical Oncology].
Rev Esp Patol 2018 Apr - Jun;51(2):84-96. Epub 2018 Jan 17.
Departamento de Anatomía Patológica, Hospital Universitario Ramón y Cajal, IRYCIS y Universidad de Alcalá, CIBERONC, Madrid, España. Electronic address:

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