Iannis Aifantis

Iannis Aifantis

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Iannis Aifantis

Iannis Aifantis

Publications by authors named "Iannis Aifantis"

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Mapping and targeting of the leukemic microenvironment.

J Exp Med 2020 Feb;217(2)

Department of Pathology, New York University School of Medicine, New York, NY.

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http://dx.doi.org/10.1084/jem.20190589DOI Listing
February 2020

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis.

Cancer Cell 2020 Jan;37(1):55-70.e15

Department of Pathology, New York University Langone Medical Center, New York, NY, USA; Interdisciplinary Melanoma Cooperative Group, New York University Langone Medical Center, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.12.007DOI Listing
January 2020

A Deep Learning Framework for Predicting Response to Therapy in Cancer.

Cell Rep 2019 Dec;29(11):3367-3373.e4

Biomedical Research Foundation of the Academy of Athens, 4 Soranou Ephessiou Str., Athens 11527, Greece; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, 75 Mikras Asias Str., Athens 11527, Greece; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, Manchester Cancer Research Centre, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester M20 4GJ, UK; 1st Department of Propaedeutic Internal Medicine, Medical School, Laikon Hospital, National and Kapodistrian University of Athens, 75 Mikras Asias Str., Athens 11527, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.017DOI Listing
December 2019

Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining.

Pharmacol Ther 2019 11 30;203:107395. Epub 2019 Jul 30.

Biomedical Research Foundation of the Academy of Athens, 4 Soranou Ephessiou Str., Athens GR-11527, Greece; Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National and Kapodistrian University of Athens, 75 Mikras Asias Str, Athens GR-11527, Greece; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, Manchester Cancer Research Centre, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester M20 4GJ, UK; Center for New Biotechnologies and Precision Medicine, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Str, Athens GR-11527, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2019.107395DOI Listing
November 2019

Immune-Based Therapies in Acute Leukemia.

Trends Cancer 2019 Oct 29;5(10):604-618. Epub 2019 Aug 29.

Department of Pathology, New York University School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.trecan.2019.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859901PMC
October 2019

Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21.

Biochim Biophys Acta Mol Basis Dis 2019 Sep 26;1865(9):2125-2137. Epub 2019 Apr 26.

Metabolic Biology Laboratory, Lewis Katz School of Medicine at Temple University, Center for Translational Medicine, Department of Pharmacology, Philadelphia, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439193012
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http://dx.doi.org/10.1016/j.bbadis.2019.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614009PMC
September 2019

3D Chromosomal Landscapes in Hematopoiesis and Immunity.

Trends Immunol 2019 Sep 15;40(9):809-824. Epub 2019 Aug 15.

Department of Pathology, New York University School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718347PMC
September 2019

Analysis of mutations in paroxysmal nocturnal hemoglobinuria (PNH).

Exp Hematol Oncol 2019 21;8:17. Epub 2019 Aug 21.

6Division of Hematology, Laura and Isaac Perlmutter Cancer Center, NYU Langone Health and the NYU School of Medicine, 240 East 38th Street, 19th Floor, New York, NY 10016 USA.

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http://dx.doi.org/10.1186/s40164-019-0142-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702710PMC
August 2019

Splicing the innate immune signalling in leukaemia.

Nat Cell Biol 2019 05;21(5):536-537

Department of Pathology and Laura & Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41556-019-0323-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880928PMC
May 2019

Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice.

Cell Rep 2019 01;26(1):108-118.e4

Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA; Department of Urology, New York University School of Medicine, New York, NY 10016, USA; Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.12.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362848PMC
January 2019

Vitamin C in Stem Cell Reprogramming and Cancer.

Trends Cell Biol 2018 09 30;28(9):698-708. Epub 2018 Apr 30.

Department of Pathology, New York University (NYU) School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2018.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102081PMC
September 2018

Harald von Boehmer 1942-2018.

Nat Immunol 2018 Sep;19(9):899

Apple Tree Partners, New York, NY, USA.

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http://dx.doi.org/10.1038/s41590-018-0192-1DOI Listing
September 2018

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.

Cell Rep 2018 09;24(11):3045-3060.e5

Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA; Department of Pathology, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.08.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170166PMC
September 2018

The effect of chromatin states on cancer: big data lead the way.

Lancet Haematol 2018 06;5(6):e237-e238

Department of Pathology and Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523026183006
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http://dx.doi.org/10.1016/S2352-3026(18)30066-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880929PMC
June 2018

Role of Dysregulated Cytokine Signaling and Bacterial Triggers in the Pathogenesis of Cutaneous T-Cell Lymphoma.

J Invest Dermatol 2018 05 8;138(5):1116-1125. Epub 2017 Nov 8.

Department of Pathology, New York University School of Medicine, New York, New York, USA; Laura and Isaac Perlmutter Cancer Institute, New York University School of Medicine, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912980PMC
May 2018

Apoptosis, Up the Ante.

Cancer Cell 2017 10;32(4):402-403

Department of Pathology, Laura & Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.09.009DOI Listing
October 2017

lncRNA-screen: an interactive platform for computationally screening long non-coding RNAs in large genomics datasets.

BMC Genomics 2017 06 5;18(1):434. Epub 2017 Jun 5.

Department of Pathology and Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY, 10016, USA.

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http://dx.doi.org/10.1186/s12864-017-3817-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458484PMC
June 2017

RNA-binding proteins, the guardians of the marginal zone.

Nat Immunol 2017 05;18(6):595-597

Department of Pathology; Laura &Isaac Perlmutter Cancer Center, and Helen L. &Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3752DOI Listing
May 2017

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.

Nat Commun 2017 04 25;8:15102. Epub 2017 Apr 25.

Department of Biochemistry and Molecular Biology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, 1011 NW 15th Street, Room 411, Gautier Building, MC R629, Miami, Florida 33136, USA.

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http://dx.doi.org/10.1038/ncomms15102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414116PMC
April 2017

Alternative roles for oxidized mCs and TETs.

Curr Opin Genet Dev 2017 Feb 7;42:1-7. Epub 2016 Dec 7.

Department of Pathology, NYU School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.gde.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446793PMC
February 2017

Beating the Clock in T-cell Acute Lymphoblastic Leukemia.

Clin Cancer Res 2017 Feb 22;23(4):873-875. Epub 2016 Dec 22.

Department of Pediatrics, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2825DOI Listing
February 2017

FBXW7 inactivation in a Braf -driven mouse model leads to melanoma development.

Pigment Cell Melanoma Res 2017 01 4;30(6):571-574. Epub 2017 Jul 4.

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1111/pcmr.12603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668175PMC
January 2017

Emerging concepts of epigenetic dysregulation in hematological malignancies.

Nat Immunol 2016 09 1;17(9):1016-24. Epub 2016 Aug 1.

Department of Pathology and Perlmutter Cancer Center, New York University School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134743PMC
September 2016

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.

Cancer Cell 2016 08 14;30(2):337-348. Epub 2016 Jul 14.

The Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, ON M5G 2C1, Canada; The Princess Margaret Cancer Centre and Ontario Cancer Institute, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022794PMC
August 2016

The Impact of DNA Methylation in Hematopoietic Malignancies.

Trends Cancer 2016 Feb;2(2):70-83

Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, NY, 10016, USA; Laura and Isaac Perlmutter Cancer Center and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY, 10016, USA.

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http://www.cell.com/trends/cancer/pdf/S2405-8033(15)00089-8.
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http://linkinghub.elsevier.com/retrieve/pii/S240580331500089
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http://dx.doi.org/10.1016/j.trecan.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806338PMC
February 2016

Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function.

Circ Res 2016 Jan 16;118(2):241-53. Epub 2015 Nov 16.

From the Metabolic Biology Laboratory, Department of Pharmacology, Center for Translational Medicine, Temple University School of Medicine, Philadelphia, PA (K.D., C.J.P., M.-C.V.); Institute of Molecular Biosciences, University of Graz, Graz, Austria (N.M.P.); Howard Hughes Medical Institute, Department of Pathology, New York University School of Medicine (P.N., I.A.); Division of Endocrinology, Diabetes, and Metabolism, New York University-Langone School of Medicine (F.W., C.M.T., Y.H., I.J.G.); and Division of Molecular Cardiology, Department of Medicine, Texas A & M Health Science Center, Temple (S.G.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886555PMC
January 2016

Emerging roles for the FBXW7 ubiquitin ligase in leukemia and beyond.

Curr Opin Cell Biol 2015 Dec 28;37:28-34. Epub 2015 Sep 28.

Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, NY 10016, USA; NYU Cancer Institute and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ceb.2015.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687017PMC
December 2015

Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms.

J Exp Med 2015 Oct 5;212(11):1833-50. Epub 2015 Oct 5.

Howard Hughes Medical Institute, Department of Pathology, and Center for Health Informatics and Bioinformatics, School of Medicine and Department of Biology, Center for Genomics and Systems Biology, New York University, New York, NY 10016 Howard Hughes Medical Institute, Department of Pathology, and Center for Health Informatics and Bioinformatics, School of Medicine and Department of Biology, Center for Genomics and Systems Biology, New York University, New York, NY 10016

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http://dx.doi.org/10.1084/jem.20151323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612095PMC
October 2015

TET1 is a tumor suppressor of hematopoietic malignancy.

Nat Immunol 2015 Jun 13;16(6):653-62. Epub 2015 Apr 13.

1] Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, New York, USA. [2] NYU Cancer Institute and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545281PMC
June 2015

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance.

Cancer Cell 2015 Jun;27(6):755-68

Skirball Institute of Biomolecular Medicine, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA; Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461838PMC
June 2015

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.

Cancer Cell 2015 Apr;27(4):502-15

Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518555PMC
April 2015

The pre-BCR to the rescue: therapeutic targeting of pre-B cell ALL.

Cancer Cell 2015 Mar;27(3):321-3

Department of Pathology and Howard Hughes Medical Institute, NYU School of Medicine New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532279PMC
March 2015

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.

Nature 2014 Oct 17;514(7523):513-7. Epub 2014 Aug 17.

1] Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, New York 10016, USA [2] NYU Cancer Institute and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nature13605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209203PMC
October 2014

STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation.

Blood 2014 Oct 22;124(14):2252-61. Epub 2014 Aug 22.

Department of Pathology and NYU Cancer Institute, New York University School of Medicine, New York, NY.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-02-48
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http://dx.doi.org/10.1182/blood-2013-02-484196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183984PMC
October 2014

Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes.

Cell Rep 2014 Oct 26;9(1):234-247. Epub 2014 Sep 26.

Department of Pathology, New York University School of Medicine, and Perlmutter Cancer Center, New York, NY 10016, USA; Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU Langone Medical Center, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.08.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317728PMC
October 2014

Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia.

Cell 2014 Jul;158(3):593-606

Howard Hughes Medical Institute, Laura and Isaac Perlmutter Cancer Center, and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, 550 First Avenue, New York, NY 10016, USA; Department of Pathology, NYU School of Medicine, 550 First Avenue, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.05.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131209PMC
July 2014

Notch signaling: switching an oncogene to a tumor suppressor.

Blood 2014 Apr 7;123(16):2451-9. Epub 2014 Mar 7.

Howard Hughes Medical Institute and Department of Pathology, New York University School of Medicine, New York, NY;

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http://www.bloodjournal.org/content/123/16/2451.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-08-35
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http://dx.doi.org/10.1182/blood-2013-08-355818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990910PMC
April 2014

Regulation of stem cell function by protein ubiquitylation.

EMBO Rep 2014 Apr 20;15(4):365-82. Epub 2014 Mar 20.

Howard Hughes Medical Institute New York University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1002/embr.201338373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989668PMC
April 2014

From fly wings to targeted cancer therapies: a centennial for notch signaling.

Cancer Cell 2014 Mar;25(3):318-34

Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, NY 10016, USA; NYU Cancer Institute and Helen L. and Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040351PMC
March 2014

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.

J Exp Med 2013 Nov 11;210(12):2641-59. Epub 2013 Nov 11.

Human Oncology and Pathogenesis Program, 2 Leukemia Service, 3 Gerstner Sloan-Kettering Graduate School of Biomedical Sciences, and 4 Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.

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http://dx.doi.org/10.1084/jem.20131141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832937PMC
November 2013

Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis.

Cell Rep 2013 Sep 5;4(5):1022-34. Epub 2013 Sep 5.

Department of Genetic Medicine, Ansary Stem Cell Instiute, Weill Cornell Medical College, New York, NY 10021, USA; Department of Surgery, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.07.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805263PMC
September 2013

In vivo mapping of notch pathway activity in normal and stress hematopoiesis.

Cell Stem Cell 2013 Aug 20;13(2):190-204. Epub 2013 Jun 20.

Howard Hughes Medical Institute and NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S19345909130020
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http://dx.doi.org/10.1016/j.stem.2013.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902172PMC
August 2013

Fingerprinting acute leukemia: DNA methylation profiling of B-acute lymphoblastic leukemia.

Cancer Discov 2012 Nov;2(11):976-8

Department of Pathology and Howard Hughes Medical Institute, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307588PMC
November 2012

The taming of the NF-κB: PP4R1 navigates while PP4c dephosphorylates.

Immunity 2012 Oct;37(4):594-6

Howard Hughes Medical Institute, New York University School of Medicine, NY 10016, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10747613120043
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http://dx.doi.org/10.1016/j.immuni.2012.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493159PMC
October 2012

Regulation of hematopoietic stem cell fate by the ubiquitin proteasome system.

Trends Immunol 2012 Jul 18;33(7):357-63. Epub 2012 Feb 18.

Department of Pathology and NYU Cancer Institute, NYU School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.it.2012.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694760PMC
July 2012

Hijacking T cell differentiation: new insights in TLX function in T-ALL.

Cancer Cell 2012 Apr;21(4):453-5

Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902167PMC
April 2012

T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling.

Proc Natl Acad Sci U S A 2011 Dec 22;108(50):20060-5. Epub 2011 Nov 22.

Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.1110230108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250146PMC
December 2011

TET family proteins and their role in stem cell differentiation and transformation.

Cell Stem Cell 2011 Sep;9(3):193-204

Howard Hughes Medical Institute, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.stem.2011.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244690PMC
September 2011

Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think.

J Exp Med 2011 Sep;208(10):1931-5

Howard Hughes Medical Institute and Department of Pathology, New York University School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1084/jem.20111855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182047PMC
September 2011