Ian R A Mackenzie

Ian R A Mackenzie

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Ian R A Mackenzie

Ian R A Mackenzie

Publications by authors named "Ian R A Mackenzie"

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Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 Jun 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Authors:
Cyril Pottier Xiaolai Zhou Ralph B Perkerson Matt Baker Gregory D Jenkins Daniel J Serie Roberta Ghidoni Luisa Benussi Giuliano Binetti Adolfo López de Munain Miren Zulaica Fermin Moreno Isabelle Le Ber Florence Pasquier Didier Hannequin Raquel Sánchez-Valle Anna Antonell Albert Lladó Tammee M Parsons NiCole A Finch Elizabeth C Finger Carol F Lippa Edward D Huey Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Robert A Rissman Jaroslaw Slawek Emilia Sitek Peter Johannsen Jørgen E Nielsen Yingxue Ren Marka van Blitterswijk Mariely DeJesus-Hernandez Elizabeth Christopher Melissa E Murray Kevin F Bieniek Bret M Evers Camilla Ferrari Sara Rollinson Anna Richardson Elio Scarpini Giorgio G Fumagalli Alessandro Padovani John Hardy Parastoo Momeni Raffaele Ferrari Francesca Frangipane Raffaele Maletta Maria Anfossi Maura Gallo Leonard Petrucelli EunRan Suh Oscar L Lopez Tsz H Wong Jeroen G J van Rooij Harro Seelaar Simon Mead Richard J Caselli Eric M Reiman Marwan Noel Sabbagh Mads Kjolby Anders Nykjaer Anna M Karydas Adam L Boxer Lea T Grinberg Jordan Grafman Salvatore Spina Adrian Oblak M-Marsel Mesulam Sandra Weintraub Changiz Geula John R Hodges Olivier Piguet William S Brooks David J Irwin John Q Trojanowski Edward B Lee Keith A Josephs Joseph E Parisi Nilüfer Ertekin-Taner David S Knopman Benedetta Nacmias Irene Piaceri Silvia Bagnoli Sandro Sorbi Marla Gearing Jonathan Glass Thomas G Beach Sandra E Black Mario Masellis Ekaterina Rogaeva Jean-Paul Vonsattel Lawrence S Honig Julia Kofler Amalia C Bruni Julie Snowden David Mann Stuart Pickering-Brown Janine Diehl-Schmid Juliane Winkelmann Daniela Galimberti Caroline Graff Linn Öijerstedt Claire Troakes Safa Al-Sarraj Carlos Cruchaga Nigel J Cairns Jonathan D Rohrer Glenda M Halliday John B Kwok John C van Swieten Charles L White Bernardino Ghetti Jill R Murell Ian R A Mackenzie Ging-Yuek R Hsiung Barbara Borroni Giacomina Rossi Fabrizio Tagliavini Zbigniew K Wszolek Ronald C Petersen Eileen H Bigio Murray Grossman Vivianna M Van Deerlin William W Seeley Bruce L Miller Neill R Graff-Radford Bradley F Boeve Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Lancet Neurol 2018 06 30;17(6):548-558. Epub 2018 Apr 30.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30126-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237181PMC
June 2018

Fused in Sarcoma Neuropathology in Neurodegenerative Disease.

Cold Spring Harb Perspect Med 2017 Dec 1;7(12). Epub 2017 Dec 1.

Department of Neuropathology, University of Tübingen and German Center for Neurodegenerative Diseases (DZNE), Tübingen 72076, Germany.

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http://dx.doi.org/10.1101/cshperspect.a024299DOI Listing
December 2017

An Unusual Case of Rabies Encephalitis.

Can J Neurol Sci 2016 Nov 31;43(6):852-855. Epub 2016 Aug 31.

3Department of Pathology and Laboratory Medicine,Vancouver Coastal Health and the University of British Columbia,Vancouver,Canada.

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http://dx.doi.org/10.1017/cjn.2016.287DOI Listing
November 2016

Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies.

J Neurochem 2016 08 15;138 Suppl 1:54-70. Epub 2016 Jun 15.

Department of Neuropathology, University of Tübingen and German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.1111/jnc.13588DOI Listing
August 2016

Two cases of rheumatoid meningitis.

Neuropathology 2016 Feb 8;36(1):93-102. Epub 2015 Sep 8.

Section of Neuropathology, Department of Pathology and Laboratory Medicine.

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http://dx.doi.org/10.1111/neup.12238DOI Listing
February 2016

Frontotemporal dementia and its subtypes: a genome-wide association study.

Authors:
Raffaele Ferrari Dena G Hernandez Michael A Nalls Jonathan D Rohrer Adaikalavan Ramasamy John B J Kwok Carol Dobson-Stone William S Brooks Peter R Schofield Glenda M Halliday John R Hodges Olivier Piguet Lauren Bartley Elizabeth Thompson Eric Haan Isabel Hernández Agustín Ruiz Mercè Boada Barbara Borroni Alessandro Padovani Carlos Cruchaga Nigel J Cairns Luisa Benussi Giuliano Binetti Roberta Ghidoni Gianluigi Forloni Daniela Galimberti Chiara Fenoglio Maria Serpente Elio Scarpini Jordi Clarimón Alberto Lleó Rafael Blesa Maria Landqvist Waldö Karin Nilsson Christer Nilsson Ian R A Mackenzie Ging-Yuek R Hsiung David M A Mann Jordan Grafman Christopher M Morris Johannes Attems Timothy D Griffiths Ian G McKeith Alan J Thomas P Pietrini Edward D Huey Eric M Wassermann Atik Baborie Evelyn Jaros Michael C Tierney Pau Pastor Cristina Razquin Sara Ortega-Cubero Elena Alonso Robert Perneczky Janine Diehl-Schmid Panagiotis Alexopoulos Alexander Kurz Innocenzo Rainero Elisa Rubino Lorenzo Pinessi Ekaterina Rogaeva Peter St George-Hyslop Giacomina Rossi Fabrizio Tagliavini Giorgio Giaccone James B Rowe Johannes C M Schlachetzki James Uphill John Collinge Simon Mead Adrian Danek Vivianna M Van Deerlin Murray Grossman John Q Trojanowski Julie van der Zee William Deschamps Tim Van Langenhove Marc Cruts Christine Van Broeckhoven Stefano F Cappa Isabelle Le Ber Didier Hannequin Véronique Golfier Martine Vercelletto Alexis Brice Benedetta Nacmias Sandro Sorbi Silvia Bagnoli Irene Piaceri Jørgen E Nielsen Lena E Hjermind Matthias Riemenschneider Manuel Mayhaus Bernd Ibach Gilles Gasparoni Sabrina Pichler Wei Gu Martin N Rossor Nick C Fox Jason D Warren Maria Grazia Spillantini Huw R Morris Patrizia Rizzu Peter Heutink Julie S Snowden Sara Rollinson Anna Richardson Alexander Gerhard Amalia C Bruni Raffaele Maletta Francesca Frangipane Chiara Cupidi Livia Bernardi Maria Anfossi Maura Gallo Maria Elena Conidi Nicoletta Smirne Rosa Rademakers Matt Baker Dennis W Dickson Neill R Graff-Radford Ronald C Petersen David Knopman Keith A Josephs Bradley F Boeve Joseph E Parisi William W Seeley Bruce L Miller Anna M Karydas Howard Rosen John C van Swieten Elise G P Dopper Harro Seelaar Yolande A L Pijnenburg Philip Scheltens Giancarlo Logroscino Rosa Capozzo Valeria Novelli Annibale A Puca Massimo Franceschi Alfredo Postiglione Graziella Milan Paolo Sorrentino Mark Kristiansen Huei-Hsin Chiang Caroline Graff Florence Pasquier Adeline Rollin Vincent Deramecourt Florence Lebert Dimitrios Kapogiannis Luigi Ferrucci Stuart Pickering-Brown Andrew B Singleton John Hardy Parastoo Momeni

Lancet Neurol 2014 Jul;13(7):686-99

Laboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Science Center, Lubbock, Texas, USA.

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http://dx.doi.org/10.1016/S1474-4422(14)70065-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112126PMC
July 2014

The neuropathology associated with repeat expansions in the C9ORF72 gene.

Acta Neuropathol 2014 Mar 20;127(3):347-57. Epub 2013 Dec 20.

Department of Pathology, University of British Columbia and Vancouver General Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1007/s00401-013-1232-4DOI Listing
March 2014

Early dipeptide repeat pathology in a frontotemporal dementia kindred with C9ORF72 mutation and intellectual disability.

Acta Neuropathol 2014 Mar 21;127(3):451-8. Epub 2014 Jan 21.

Department of Neurology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK,

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http://dx.doi.org/10.1007/s00401-014-1245-7DOI Listing
March 2014

Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.

Nat Neurosci 2013 Oct 15;16(10):1383-91. Epub 2013 Sep 15.

1] Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. [2] Howard Hughes Medical Institute, Chevy Chase, Maryland, USA. [3].

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http://dx.doi.org/10.1038/nn.3514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564396PMC
October 2013

Angiotropism in primary cutaneous melanoma with brain metastasis: a study of 20 cases.

Am J Dermatopathol 2013 Aug;35(6):650-4

Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1097/DAD.0b013e31827e8315ADDOI Listing
August 2013

Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects.

Acta Neuropathol 2012 Sep 10;124(3):373-82. Epub 2012 Aug 10.

Neuroscience Research Australia, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1007/s00401-012-1030-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445027PMC
September 2012

FET proteins in frontotemporal dementia and amyotrophic lateral sclerosis.

Brain Res 2012 Jun 13;1462:40-3. Epub 2011 Dec 13.

Department of Pathology, Vancouver General Hospital, 855 West 12th Avenue, Vancouver, BC, Canada V5Z 1M9.

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http://dx.doi.org/10.1016/j.brainres.2011.12.010DOI Listing
June 2012

Synaptic dysfunction in progranulin-deficient mice.

Neurobiol Dis 2012 Feb 25;45(2):711-22. Epub 2011 Oct 25.

Centre for Molecular Medicine & Therapeutics, Department of Medical Genetics, University of British Columbia, and Children's and Women's Hospital, 980 West 28th Avenue, Vancouver, BC, Canada V5Z 4H4.

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http://dx.doi.org/10.1016/j.nbd.2011.10.016DOI Listing
February 2012

Novel types of frontotemporal lobar degeneration: beyond tau and TDP-43.

J Mol Neurosci 2011 Nov 21;45(3):402-8. Epub 2011 May 21.

Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, 855 West 12th Avenue, Vancouver, BC, V5Z 1M9, Canada.

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http://dx.doi.org/10.1007/s12031-011-9551-1DOI Listing
November 2011

Distinct pathological subtypes of FTLD-FUS.

Acta Neuropathol 2011 Feb 30;121(2):207-18. Epub 2010 Oct 30.

Department of Pathology, Vancouver General Hospital, University of British Columbia, BC, Canada.

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http://link.springer.com/10.1007/s00401-010-0764-0
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http://dx.doi.org/10.1007/s00401-010-0764-0DOI Listing
February 2011

rs5848 polymorphism and serum progranulin level.

J Neurol Sci 2011 Jan 2;300(1-2):28-32. Epub 2010 Nov 2.

Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1016/j.jns.2010.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085023PMC
January 2011

FUS-immunoreactive intranuclear inclusions in neurodegenerative disease.

Brain Pathol 2010 May 21;20(3):589-97. Epub 2009 Sep 21.

Cancer Therapeutics Group, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1750-3639.2009.00337.xDOI Listing
May 2010

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Authors:
Vivianna M Van Deerlin Patrick M A Sleiman Maria Martinez-Lage Alice Chen-Plotkin Li-San Wang Neill R Graff-Radford Dennis W Dickson Rosa Rademakers Bradley F Boeve Murray Grossman Steven E Arnold David M A Mann Stuart M Pickering-Brown Harro Seelaar Peter Heutink John C van Swieten Jill R Murrell Bernardino Ghetti Salvatore Spina Jordan Grafman John Hodges Maria Grazia Spillantini Sid Gilman Andrew P Lieberman Jeffrey A Kaye Randall L Woltjer Eileen H Bigio Marsel Mesulam Safa Al-Sarraj Claire Troakes Roger N Rosenberg Charles L White Isidro Ferrer Albert Lladó Manuela Neumann Hans A Kretzschmar Christine Marie Hulette Kathleen A Welsh-Bohmer Bruce L Miller Ainhoa Alzualde Adolfo Lopez de Munain Ann C McKee Marla Gearing Allan I Levey James J Lah John Hardy Jonathan D Rohrer Tammaryn Lashley Ian R A Mackenzie Howard H Feldman Ronald L Hamilton Steven T Dekosky Julie van der Zee Samir Kumar-Singh Christine Van Broeckhoven Richard Mayeux Jean Paul G Vonsattel Juan C Troncoso Jillian J Kril John B J Kwok Glenda M Halliday Thomas D Bird Paul G Ince Pamela J Shaw Nigel J Cairns John C Morris Catriona Ann McLean Charles DeCarli William G Ellis Stefanie H Freeman Matthew P Frosch John H Growdon Daniel P Perl Mary Sano David A Bennett Julie A Schneider Thomas G Beach Eric M Reiman Bryan K Woodruff Jeffrey Cummings Harry V Vinters Carol A Miller Helena C Chui Irina Alafuzoff Päivi Hartikainen Danielle Seilhean Douglas Galasko Eliezer Masliah Carl W Cotman M Teresa Tuñón M Cristina Caballero Martínez David G Munoz Steven L Carroll Daniel Marson Peter F Riederer Nenad Bogdanovic Gerard D Schellenberg Hakon Hakonarson John Q Trojanowski Virginia M-Y Lee

Nat Genet 2010 Mar 14;42(3):234-9. Epub 2010 Feb 14.

[1] Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. [2] These authors contributed equally to this work.

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http://dx.doi.org/10.1038/ng.536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828525PMC
March 2010

Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease.

Acta Neuropathol 2009 Nov 9;118(5):605-16. Epub 2009 Aug 9.

Institute of Neuropathology, University Hospital of Zürich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00401-009-0581-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864784PMC
November 2009

A new subtype of frontotemporal lobar degeneration with FUS pathology.

Brain 2009 Nov 11;132(Pt 11):2922-31. Epub 2009 Aug 11.

Institute of Neuropathology, University Hospital of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1093/brain/awp214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768659PMC
November 2009

The molecular basis of frontotemporal dementia.

Expert Rev Mol Med 2009 Jul 29;11:e23. Epub 2009 Jul 29.

Institute of Neuropathology, University Hospital of Zürich, Switzerland.

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http://dx.doi.org/10.1017/S1462399409001136DOI Listing
July 2009

Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies.

Acta Neuropathol 2009 Feb 13;117(2):125-36. Epub 2009 Jan 13.

Department of Psychogeriatrics, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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http://dx.doi.org/10.1007/s00401-008-0480-1DOI Listing
February 2009

The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia.

Curr Opin Neurol 2008 Dec;21(6):693-700

Department of Pathology, Vancouver General Hospital, British Columbia, Canada.

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http://dx.doi.org/10.1097/WCO.0b013e3283168d1dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869081PMC
December 2008

TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD.

Acta Neuropathol 2008 Aug 7;116(2):147-57. Epub 2008 Jun 7.

Center for Neuropathology and Prion Research, Ludwig-Maximilians University Munich, Feodor-Lynen-Str. 23, 81377, Munich, Germany.

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http://link.springer.com/10.1007/s00401-008-0395-x
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http://dx.doi.org/10.1007/s00401-008-0395-xDOI Listing
August 2008

Atypical frontotemporal lobar degeneration with ubiquitin-positive, TDP-43-negative neuronal inclusions.

Brain 2008 May 24;131(Pt 5):1282-93. Epub 2008 Mar 24.

Department of Pathology, University of British Columbia, Vancouver General Hospital, 855 West 12th Avenue, Vancouver, British Columbia, V5Z 1M9 Canada.

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http://dx.doi.org/10.1093/brain/awn061DOI Listing
May 2008

Clinical presentation of prodromal frontotemporal dementia.

Am J Alzheimers Dis Other Demen 2007 Dec-2008 Jan;22(6):456-67

Division of Neurology, Geriatric Psychiatry Outreach Team, Vancouver Hospital, Vancouver, British Columbia.

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http://dx.doi.org/10.1177/1533317507308781DOI Listing
March 2008

The neuropathology of FTD associated With ALS.

Alzheimer Dis Assoc Disord 2007 Oct-Dec;21(4):S44-9

Department of Pathology, University of British Columbia and Vancouver General Hospital, British Columbia, Canada.

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http://dx.doi.org/10.1097/WAD.0b013e31815c3486DOI Listing
February 2008

Progranulin: normal function and role in neurodegeneration.

J Neurochem 2008 Jan 22;104(2):287-97. Epub 2007 Oct 22.

Department of Neuroscience, Mayo Clinic Jacksonville, Jacksonville, Florida, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04968.xDOI Listing
January 2008

The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments.

Neurogenetics 2007 Nov 6;8(4):237-48. Epub 2007 Sep 6.

Department of Pathology, Vancouver General Hospital, 855 West 12th Avenue, Vancouver, BC, V5Z 1M9, Canada.

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http://dx.doi.org/10.1007/s10048-007-0102-4DOI Listing
November 2007

A reassessment of the neuropathology of frontotemporal dementia linked to chromosome 3.

J Neuropathol Exp Neurol 2007 Oct;66(10):884-91

Department of Pathology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark.

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http://dx.doi.org/10.1097/nen.0b013e3181567f02DOI Listing
October 2007

Progressive anomia revisited: focal degeneration associated with progranulin gene mutation.

Neurocase 2007 Oct;13(5):366-77

School of Translational Medicine, University of Manchester, Hope Hospital, Salford, UK.

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http://dx.doi.org/10.1080/13554790701851510DOI Listing
October 2007

The neuropathology and clinical phenotype of FTD with progranulin mutations.

Acta Neuropathol 2007 Jul 26;114(1):49-54. Epub 2007 Apr 26.

Department of Pathology, Vancouver General Hospital, 855 West 12th Avenue, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s00401-007-0223-8DOI Listing
July 2007

Clinical phenotypes of Cerebral Amyloid Angiopathy.

J Neurol Sci 2007 Jun 6;257(1-2):23-30. Epub 2007 Mar 6.

Department of Neurology, Hospital Geral Santo António, Porto, Portugal.

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http://dx.doi.org/10.1016/j.jns.2007.01.054DOI Listing
June 2007

Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43.

Acta Neuropathol 2007 May 12;113(5):521-33. Epub 2007 Jan 12.

Clinical Neuroscience Research Group, Division of Medicine and Neuroscience, Greater Manchester Neurosciences Centre, Hope Hospital, University of Manchester, Salford, M6 8HD, UK,

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http://dx.doi.org/10.1007/s00401-006-0189-yDOI Listing
May 2007

Progranulin in frontotemporal lobar degeneration and neuroinflammation.

J Neuroinflammation 2007 Feb 11;4. Epub 2007 Feb 11.

Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA.

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http://dx.doi.org/10.1186/1742-2094-4-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805428PMC
February 2007

Dementia lacking distinctive histology (DLDH) revisited.

Acta Neuropathol 2006 Nov 10;112(5):551-9. Epub 2006 Aug 10.

Department of Pathology, Vancouver General Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s00401-006-0123-3DOI Listing
November 2006

The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene.

Brain 2006 Nov;129(Pt 11):3081-90

Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver Coastal Health Vancouver, BC, Canada.

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http://dx.doi.org/10.1093/brain/awl271DOI Listing
November 2006

alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases.

Acta Neuropathol 2004 Sep 28;108(3):213-23. Epub 2004 May 28.

Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, PA 19104-4283, USA.

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http://dx.doi.org/10.1007/s00401-004-0882-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516855PMC
September 2004

Neuronal intranuclear inclusions distinguish familial FTD-MND type from sporadic cases.

Dement Geriatr Cogn Disord 2004 ;17(4):333-6

Department of Pathology, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1159/000077166DOI Listing
September 2004

The neuropathology and biochemistry of frontotemporal dementia.

Ann Neurol 2003 ;54 Suppl 5:S24-8

Department of Pathology, University of Western Ontario, London, Ontario, Canada.

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http://doi.wiley.com/10.1002/ana.10571
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http://dx.doi.org/10.1002/ana.10571DOI Listing
December 2003

Neuronal intranuclear inclusions distinguish familial FTD-MND type from sporadic cases.

Acta Neuropathol 2003 Jun 15;105(6):543-8. Epub 2003 Feb 15.

Department of Pathology, Vancouver General Hospital, 855 West 12th Avenue, V5Z 1M9, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1007/s00401-003-0678-1DOI Listing
June 2003

The relationship between extramotor ubiquitin-immunoreactive neuronal inclusions and dementia in motor neuron disease.

Acta Neuropathol 2003 Feb 17;105(2):98-102. Epub 2002 Oct 17.

Department of Pathology, University of British Columbia, Vancouver General Hospital, 855 West 12th Avenue, Canada V5Z 1M9.

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http://dx.doi.org/10.1007/s00401-002-0620-yDOI Listing
February 2003