Ian N Bruce

Ian N Bruce

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The challenges in data integration - heterogeneity and complexity in clinical trials and patient registries of Systemic Lupus Erythematosus.

BMC Med Res Methodol 2020 Jun 24;20(1):164. Epub 2020 Jun 24.

Centre for Health Informatics, Vaughan Housue, Portsmouth St., The University of Manchester, Manchester, M13 9GB, UK.

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http://dx.doi.org/10.1186/s12874-020-01057-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313210PMC
June 2020

A molecular taxonomy for systemic autoimmune rheumatic diseases (SARDs): learning lessons from oncology?

Rheumatology (Oxford) 2020 Mar 17. Epub 2020 Mar 17.

Centre for Epidemiology Versus Arthritis, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/keaa097DOI Listing
March 2020

Construction of a Frailty Index as a Novel Health Measure in Systemic Lupus Erythematosus.

J Rheumatol 2020 01 15;47(1):72-81. Epub 2019 Apr 15.

From the Divisions of Rheumatology and Geriatric Medicine, Department of Medicine, Dalhousie University; Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia; Divisions of Rheumatology and Clinical Epidemiology, Department of Medicine, McGill University, Montreal; Division of Rheumatology, Centre Hospitalier Universitaire (CHU) de Québec et Université Laval, Quebec City, Quebec; Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta; Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, Ontario; University of Manitoba, Winnipeg, Manitoba; Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea; Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham; Arthritis Research UK Epidemiology Unit, Faculty of Biology Medicine and Health, Manchester Academic Health Sciences Center, The University of Manchester, and National Institute for Health Research (NIHR) Manchester Musculoskeletal Biomedical Research Centre, Manchester University National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Center, Manchester; Center for Rheumatology, Department of Medicine, University College London, London; Lanarkshire Center for Rheumatology, Hairmyres Hospital, East Kilbride, Scotland; Lupus Research Unit, The Rayne Institute, St Thomas' Hospital, King's College London School of Medicine, London, UK; Instituto Nacional de Ciencias Medicas y Nutrición, Mexico City, Mexico; Cedars-Sinai/David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma; Department of Medicine, State University of New York (SUNY) Downstate Medical Center, Brooklyn, New York; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, North Carolina; Northwestern University and Feinberg School of Medicine, Chicago, Illinois; Lupus Center of Excellence, Allegheny Health Network, Pittsburgh, Pennsylvania; Feinstein Institute for Medical Research, Manhasset, New York; Emory University School of Medicine, Division of Rheumatology, Atlanta, Georgia; Medical University of South Carolina, Charleston, South Carolina; University of California San Diego School of Medicine (UCSD), La Jolla, California; Hospital for Joint Diseases, New York University (NYU), Seligman Center for Advanced Therapeutics, New York, New York, USA; Autoimmune Diseases Research Unit, Department of Internal Medicine, BioCruces Health Research Institute, Hospital Universitario Cruces, University of the Basque Country, Barakaldo; Josep Font Autoimmune Diseases Laboratory, IDIBAPS, Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Spain; Division of Rheumatology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey; Unit for Clinical Therapy Research (ClinTRID), Karolinska Institute, Stockholm; Department of Clinical Sciences Lund, Rheumatology, Lund University, Lund, Sweden; Copenhagen Lupus and Vasculitis Clinic, Section 4242, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.181338
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http://dx.doi.org/10.3899/jrheum.181338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800806PMC
January 2020

Trial of Anifrolumab in Active Systemic Lupus Erythematosus.

N Engl J Med 2020 01 18;382(3):211-221. Epub 2019 Dec 18.

From the Centre for Inflammatory Disease, Monash University, Melbourne, VIC, Australia (E.F.M.); the Division of Rheumatology, Zucker School of Medicine at Hofstra-Northwell, Great Neck (R.F.), and the Department of Medicine, Division of Rheumatology, Columbia University College of Physicians and Surgeons, New York (A.D.A.) - both in New York; the First Department of Internal Medicine and Graduate School of Medical Science, University of Occupational and Environmental Health Japan, Kitakyushu (Y.T.); the Arthritis Research UK Centre for Epidemiology, Faculty of Biology, Medicine, and Health, University of Manchester and National Institute for Health Research Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom (I.N.B.); the Rheumatology Department, Centre Hospitalier Universitaire de Bordeaux-Groupe Hospitalier Pellegrin, and Unité Mixte de Recherche-Centre National de la Recherche Scientifique 5164, Bordeaux University, Bordeaux, France (C.R.); the Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea (S.-C.B.); AstraZeneca, Gaithersburg, MD (P.Z.B., L.P., R.T.); and AstraZeneca, Gothenburg, Sweden (A.B.).

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http://dx.doi.org/10.1056/NEJMoa1912196DOI Listing
January 2020

Altered cognitive function in systemic lupus erythematosus and associations with inflammation and functional and structural brain changes.

Ann Rheum Dis 2019 07 12;78(7):934-940. Epub 2019 Apr 12.

Arthritis Research UK Centre for Epidemiology, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK

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http://dx.doi.org/10.1136/annrheumdis-2018-214677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585286PMC
July 2019

Current challenges in the development of new treatments for lupus.

Ann Rheum Dis 2019 06 12;78(6):729-735. Epub 2019 Jan 12.

RILITE Research Institute, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1136/annrheumdis-2018-214530DOI Listing
June 2019

Osteopontin and Disease Activity in Patients with Recent-onset Systemic Lupus Erythematosus: Results from the SLICC Inception Cohort.

J Rheumatol 2019 05 15;46(5):492-500. Epub 2019 Jan 15.

From the Rheumatology/Division of Neuro and Inflammation Sciences, Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Medicine, Unit of Rheumatology, Karolinska Institutet and Karolinska University Hospital, Stockholm; Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund; Unit for Clinical Therapy Research (ClinTRID), Karolinska University, Stockholm, Sweden; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, Ontario; Division of Rheumatology, Centre Hospitalier Universitaire (CHU) de Québec - Université Laval, Quebec City, Quebec; Division of Rheumatology, Cumming School of Medicine - University of Calgary, Calgary, Alberta; Division of Rheumatology, Department of Medicine, McGill University Health Centre, Montreal, Quebec; Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia; Department of Medicine and Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, Mexico; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea; Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham; Centre for Rheumatology Research, University College, London; Lupus Research Unit, The Rayne Institute, St. Thomas' Hospital, King's College London School of Medicine, London; Lanarkshire Centre for Rheumatology, Hairmyres Hospital, East Kilbride, Scotland; Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, The University of Manchester and UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Foundation Trust, Manchester, UK; Cedars-Sinai/David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma; Department of Medicine, State University of New York (SUNY) Downstate Medical Center, Brooklyn, New York; Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama; Department of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Feinstein Institute for Medical Research, Manhasset, New York; Division of Rheumatology and Immunology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina; Autoimmunity Institute, Allegheny Health Network, Pittsburgh, Pennsylvania; Northwestern University and Feinberg School of Medicine, Chicago, Illinois; Division of Rheumatology, Emory University School of Medicine, Atlanta, Georgia; University of California San Diego School of Medicine, La Jolla, California; Division of Rheumatology, Medical University of South Carolina, Charleston, South Carolina; Division of Rheumatology, Columbia University Medical Center, New York, New York, USA; Department of Rheumatology, Center for Rheumatology Research Fossvogur Landspitali University Hospital, Reyjkavik, Iceland; Autoimmune Disease Unit, Department of Internal Medicine, Hospital Universitario Cruces, BioCruces Health Research Institute, University of the Basque Country, Barakaldo; Josep Font Autoimmune Diseases Laboratory, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Spain; Division of Rheumatology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey; Copenhagen Lupus and Vasculitis Clinic, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Rheumatology, Kantousspital, Schaffhausen, Switzerland.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.180713
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http://dx.doi.org/10.3899/jrheum.180713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339909PMC
May 2019

Clinical applications of machine learning algorithms: beyond the black box.

BMJ 2019 Mar 12;364:l886. Epub 2019 Mar 12.

Oxford Internet Institute, University of Oxford, 1 St Giles', Oxford OX1 3JS, UK.

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http://dx.doi.org/10.1136/bmj.l886DOI Listing
March 2019

Progression of subclinical and clinical cardiovascular disease in a UK SLE cohort: the role of classic and SLE-related factors.

Lupus Sci Med 2018 17;5(1):e000267. Epub 2018 Nov 17.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Faculty of Biology Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/lupus-2018-000267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257381PMC
November 2018

Drug-Induced Interstitial Lung Disease: A Systematic Review.

J Clin Med 2018 Oct 15;7(10). Epub 2018 Oct 15.

North West Lung Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M6 8HD, UK.

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http://www.mdpi.com/2077-0383/7/10/356
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http://dx.doi.org/10.3390/jcm7100356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209877PMC
October 2018

Cytokine profiling in active and quiescent SLE reveals distinct patient subpopulations.

Arthritis Res Ther 2018 08 9;20(1):173. Epub 2018 Aug 9.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1186/s13075-018-1666-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085716PMC
August 2018

QRISK3 improves detection of cardiovascular disease risk in patients with systemic lupus erythematosus.

Lupus Sci Med 2018 13;5(1):e000272. Epub 2018 Aug 13.

Translational Cardiovascular Science, The Centre for Bioscience, Manchester Metropolitan University, Manchester, UK.

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http://dx.doi.org/10.1136/lupus-2018-000272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109811PMC
August 2018

Evaluation of non-contrast MRI biomarkers in lupus nephritis.

Clin Exp Rheumatol 2017 Nov-Dec;35(6):954-958. Epub 2017 Aug 28.

Arthritis Res. Ctr. Epidemiology, Musculoskeletal Res. & Dermatological Sciences, Academic Health Science Ctr., Univ.of Manchester; and The Kellgren Ctr. for Rheumatology, NIHR Manchester Musculoskeletal Biomed. Res. Ctr., Central Manchester Univ., UK.

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March 2018

Vitamin D and systemic lupus erythematosus - The hype and the hope.

Autoimmun Rev 2018 Jan 3;17(1):19-23. Epub 2017 Nov 3.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Faculty of Biology Medicine and Health, The University of Manchester, UK; NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1016/j.autrev.2017.11.004DOI Listing
January 2018

Predictive and prognostic factors influencing outcomes of rituximab therapy in systemic lupus erythematosus (SLE): A systematic review.

Semin Arthritis Rheum 2017 12 5;47(3):384-396. Epub 2017 May 5.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; Arthritis Research UK Centre for Epidemiology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695978PMC
December 2017

Can we identify who gets benefit or harm from mycophenolate mofetil in systemic lupus erythematosus? A systematic review.

Semin Arthritis Rheum 2017 08 9;47(1):65-78. Epub 2017 Feb 9.

NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK; Arthritis Research UK Centre for Epidemiology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.01.009DOI Listing
August 2017

Clinicians approaches to management of background treatment in patients with SLE in clinical remission: results of an international observational survey.

Lupus Sci Med 2017 29;4(1):e000173. Epub 2017 Jun 29.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1136/lupus-2016-000173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724341PMC
June 2017

Vitamin D treatment for connective tissue diseases: hope beyond the hype?

Rheumatology (Oxford) 2017 02 13;56(2):178-186. Epub 2016 May 13.

Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester

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http://rheumatology.oxfordjournals.org/content/early/2016/05
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http://dx.doi.org/10.1093/rheumatology/kew212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854035PMC
February 2017

Drug-specific risk and characteristics of lupus and vasculitis-like events in patients with rheumatoid arthritis treated with TNFi: results from BSRBR-RA.

RMD Open 2017 17;3(1):e000314. Epub 2017 Jan 17.

Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; National Institute of Health Research Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2016-00031
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http://dx.doi.org/10.1136/rmdopen-2016-000314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255894PMC
January 2017

Vitamin D improves endothelial dysfunction and restores myeloid angiogenic cell function via reduced CXCL-10 expression in systemic lupus erythematosus.

Sci Rep 2016 Mar 1;6:22341. Epub 2016 Mar 1.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/srep22341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772382PMC
March 2016

Cardiovascular risk and its modification in patients with connective tissue diseases.

Best Pract Res Clin Rheumatol 2016 02 26;30(1):81-94. Epub 2016 May 26.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.berh.2016.03.003DOI Listing
February 2016

Medication-related side effects in vasculitis: a patient self-report survey of awareness and reported uptake of protective therapy.

Rheumatology (Oxford) 2016 Jan 28;55(1):185-6. Epub 2015 Aug 28.

Renal Unit, Manchester Royal Infirmary, Central Manchester Foundation Trust.

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http://dx.doi.org/10.1093/rheumatology/kev303DOI Listing
January 2016

PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus.

Ann Rheum Dis 2015 Oct 28;74(10):1882-5. Epub 2015 Apr 28.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute for Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK The Kellgren Centre for Rheumatology, Central Manchester Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2014-207187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602265PMC
October 2015

The influence of behavioural and psychological factors on medication adherence over time in rheumatoid arthritis patients: a study in the biologics era.

Rheumatology (Oxford) 2015 Oct 13;54(10):1780-91. Epub 2015 May 13.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospital NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/kev105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571488PMC
October 2015

Atherosclerosis in rheumatoid arthritis: is it all about inflammation?

Nat Rev Rheumatol 2015 Jul 31;11(7):390-400. Epub 2015 Mar 31.

NIHR Manchester Musculoskeletal Biomedical Research Unit, and Kellgren Centre for Rheumatology, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1038/nrrheum.2015.40DOI Listing
July 2015

Indications for IVIG in rheumatic diseases.

Rheumatology (Oxford) 2015 Mar 17;54(3):383-91. Epub 2014 Nov 17.

Christie NHS Foundation Trust, Arthritis Research UK Epidemiology Unit, Institute of Inflammation and Repair, Manchester Academic Health Sciences Centre, University of Manchester and Kellgren Centre for Rheumatology, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK Christie NHS Foundation Trust, Arthritis Research UK Epidemiology Unit, Institute of Inflammation and Repair, Manchester Academic Health Sciences Centre, University of Manchester and Kellgren Centre for Rheumatology, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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http://dx.doi.org/10.1093/rheumatology/keu429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334686PMC
March 2015

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.

Nat Commun 2015 Feb 5;6:6046. Epub 2015 Feb 5.

1] Arthritis Research UK Centre for Genetics and Genomics, The University of Manchester, Manchester M13 9PT, UK [2] NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academy of Health Sciences, Manchester M13 9WU, UK.

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http://dx.doi.org/10.1038/ncomms7046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327416PMC
February 2015

Suppression of inflammation reduces endothelial microparticles in active systemic lupus erythematosus.

Ann Rheum Dis 2014 Jun 5;73(6):1144-50. Epub 2013 May 5.

Arthritis Research UK Epidemiology Unit, Institute of Inflammation and Repair, Manchester Academic Health Sciences Centre, University of Manchester, , Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-203028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033120PMC
June 2014

Improving cardiovascular outcomes in rheumatic diseases: therapeutic potential of circulating endothelial progenitor cells.

Pharmacol Ther 2014 May 12;142(2):231-43. Epub 2013 Dec 12.

Institute of Cardiovascular Sciences, Manchester Academic Health Sciences Centre, The University of Manchester, UK; Healthcare Science Research Institute, Manchester Metropolitan University, UK Healthcare Science Research Institute, Manchester Metropolitan University, UK.

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http://dx.doi.org/10.1016/j.pharmthera.2013.12.008DOI Listing
May 2014

The effect of type 1 IFN on human aortic endothelial cell function in vitro: relevance to systemic lupus erythematosus.

J Interferon Cytokine Res 2014 May 20;34(5):404-12. Epub 2014 Jan 20.

1 Arthritis Research UK Epidemiology Unit, Institute of Inflammation and Repair, Manchester Academic Health Sciences Centre, The University of Manchester , Manchester, United Kingdom .

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http://dx.doi.org/10.1089/jir.2013.0016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015474PMC
May 2014

American College of Rheumatology criteria at inception, and accrual over 5 years in the SLICC inception cohort.

J Rheumatol 2014 May 1;41(5):875-80. Epub 2014 Apr 1.

From the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada; Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico; Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Department of Rheumatology, Hospital for Rheumatic Diseases and Hanyang University Medical Center, Seoul, Korea; Divisions of Clinical Immunology/Allergy and Clinical Epidemiology, Montreal General Hospital and McGill University Health Centre, Montreal, Quebec, Canada; Centre Hospitalier Universitaire de Québec et Université Laval, Quebec City, Quebec, Canada; Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada; Centre for Rheumatology Research, University College, London, UK; Cedars-Sinai/David Geffen School of Medicine, University of California, Los Angeles, California, USA; Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, USA; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA; Department of Rheumatology, University Hospital Lund, Lund, Sweden; Division of Rheumatology and Immunology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA; Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama, Birmingham, Alabama, USA; Center for Rheumatology Research, Landspitali University Hospital, Reyjkavik, Iceland; Northwestern University and Feinber

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http://dx.doi.org/10.3899/jrheum.130704DOI Listing
May 2014

N-terminal pro-brain-type natriuretic peptide (NT-pro-BNP) and mortality risk in early inflammatory polyarthritis: results from the Norfolk Arthritis Registry (NOAR).

Ann Rheum Dis 2014 Apr 19;73(4):684-90. Epub 2013 Mar 19.

Arthritis Research UK Epidemiology Unit, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, , Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-202848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963600PMC
April 2014

Identification of multiple, oxygen-stable HIF1 alpha isoforms, and augmented expression of adrenomedullin in rheumatoid arthritis.

Clin Exp Rheumatol 2013 Sep-Oct;31(5):672-82. Epub 2013 Apr 22.

School of Medicine and Manchester Academic Health Sciences Centre, University of Manchester, UK.

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December 2013

The systemic lupus international collaborating clinics (SLICC) damage index: a systematic literature review.

Semin Arthritis Rheum 2013 Dec 17;43(3):352-61. Epub 2013 Jun 17.

Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2013.05.003DOI Listing
December 2013

Cardiovascular risk and inflammatory rheumatic diseases.

Clin Med (Lond) 2013 Aug;13(4):395-7

Arthritis Research UK Epidemiology Unit, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.7861/clinmedicine.13-4-395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954310PMC
August 2013

Certolizumab pegol attenuates the pro-inflammatory state in endothelial cells in a manner that is atheroprotective.

Clin Exp Rheumatol 2013 Mar-Apr;31(2):225-33. Epub 2012 Dec 13.

University of Manchester, UK.

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June 2013

Serum cystatin C is independently associated with renal impairment and high sensitivity C-reactive protein in systemic lupus erythematosus.

Clin Exp Rheumatol 2013 Mar-Apr;31(2):251-5. Epub 2012 Dec 17.

The Kellgren Centre for Rheumatology, Central Manchester Foundation Trust, Manchester, UK.

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June 2013

Regulatory T cells in systemic lupus erythematosus and pregnancy.

Am J Reprod Immunol 2013 Jun 8;69(6):588-95. Epub 2013 Feb 8.

Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, St Mary's Hospital, and Faculty of Medical and Human Sciences, Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1111/aji.12081DOI Listing
June 2013

Shortened telomere length in patients with systemic lupus erythematosus.

Arthritis Rheum 2013 May;65(5):1319-23

Manchester Academic Health Science Centre and University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1002/art.37895
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http://dx.doi.org/10.1002/art.37895DOI Listing
May 2013

Treat-to-target in systemic lupus erythematosus: where are we today?

Clin Exp Rheumatol 2012 Jul-Aug;30(4 Suppl 73):S112-5. Epub 2012 Nov 20.

Rheumatology Unit, Department of Internal Medicine, University of Pisa, Italy.

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http://www.lupus-europe.org/IMG/pdf/t2t-sle-annrheumdis-2013
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March 2013

Seropositivity is associated with insulin resistance in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register (NOAR): an observational study.

Arthritis Res Ther 2011 29;13(5):R159. Epub 2011 Sep 29.

Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1186/ar3476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308090PMC
December 2012

Recommendations for the use of rituximab in anti-neutrophil cytoplasm antibody-associated vasculitis.

Rheumatology (Oxford) 2012 Apr 25;51(4):634-43. Epub 2011 May 25.

Vasculitis and Lupus Unit, Box 57, Department of Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/ker150DOI Listing
April 2012

Golimumab for the treatment of psoriatic arthritis: a NICE single technology appraisal.

Pharmacoeconomics 2012 Apr;30(4):257-70

Centre for Reviews and Dissemination, University of York, York, UK.

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http://dx.doi.org/10.2165/11595920-000000000-00000DOI Listing
April 2012

Construct and criterion validity of the short form-6D utility measure in patients with systemic lupus erythematosus.

J Rheumatol 2012 Apr 1;39(4):735-42. Epub 2012 Feb 1.

Address correspondence to Prof. I. Bruce, Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Sciences Centre, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.3899/jrheum.110648DOI Listing
April 2012

Modifiable risk factors for RA: prevention, better than cure?

Rheumatology (Oxford) 2012 Mar 24;51(3):499-512. Epub 2011 Nov 24.

The University of Manchester, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/ker299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281496PMC
March 2012

Endothelial progenitor cells: a new player in lupus?

Arthritis Res Ther 2012 Feb 20;14(1):203. Epub 2012 Feb 20.

Arthritis Research UK Epidemiology Unit, School of Translational Medicine, Manchester Academic Health Science Centre, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1186/ar3700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392811PMC
February 2012

Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis.

Ann Rheum Dis 2011 Sep 29;70(9):1641-4. Epub 2011 May 29.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/ard.2011.150102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147229PMC
September 2011

Systemic lupus erythematosus, regulatory T cells and pregnancy.

Expert Rev Clin Immunol 2011 Sep;7(5):635-48

Maternal and Fetal Health Research Centre, University of Manchester, St Mary's hospital, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1586/eci.11.59DOI Listing
September 2011

Cardiovascular risk factors in inflammatory arthritis.

Curr Opin Lipidol 2011 Aug;22(4):296-301

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, The University of Manchester.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOL.0b013e3283488c50DOI Listing
August 2011