Publications by authors named "Ian G McKeith"

100Publications

Cholinergic muscarinic M/M receptor networks in dementia with Lewy bodies.

Brain Commun 2020 15;2(2):fcaa098. Epub 2020 Jul 15.

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK.

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http://dx.doi.org/10.1093/braincomms/fcaa098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475694PMC
July 2020

Cognitive Decline in Mild Cognitive Impairment With Lewy Bodies or Alzheimer Disease: A Prospective Cohort Study.

Am J Geriatr Psychiatry 2020 Aug 8. Epub 2020 Aug 8.

Translational and Clinical Research Institute, Biomedical Research Building, Newcastle University (CAH, PCD, J-PT, NB, KO, IGM, AJT), Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.jagp.2020.07.018DOI Listing
August 2020

The challenges of COVID-19 for people with dementia with Lewy bodies and family caregivers.

Int J Geriatr Psychiatry 2020 Aug 3. Epub 2020 Aug 3.

Translational and Clinical Research Institute, Biomedical Research Building, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/gps.5393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436139PMC
August 2020

Prospective predictors of decline stability in mild cognitive impairment with Lewy bodies or Alzheimer's disease.

Psychol Med 2020 May 5:1-9. Epub 2020 May 5.

Translational and Clinical Research Institute, Biomedical Research Building, Newcastle University, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1017/S0033291720001130DOI Listing
May 2020

Research criteria for the diagnosis of prodromal dementia with Lewy bodies.

Neurology 2020 04 2;94(17):743-755. Epub 2020 Apr 2.

From the Newcastle University (I.G.M., A.J.T., P.D., J.P.T.); Mayo Clinic (T.J.F.), Jacksonville; University of Strasbourg (F.B.); Mayo Clinic (B.F.B., K.K.), Rochester; Nagoya University (H.F.), Kawasaki Memorial Hospital; Istituto Neurologico "Carlo Besta" (C.M., P.T.), Milan; Cambridge University (F.M.S.); McGill University (R.B.P.); King's College London and Stavanger University Hospital (D.A.); University of Exeter (C.B.); University of Chieti-Pescara (L.B.); Istanbul Faculty of Medicine (M.E.); University of Miami Miller School of Medicine (J.E.G.); University of California (D.G., D.P.S.), San Diego; Feinberg School of Medicine (J.G.G.); Massachusetts General Hospital (S.N.G.); Columbia University Irving Medical Center (L.S.H., K.S.M.); Osaka University (M.I.); Lou Ruvo Center of Brain Health (J.B.L.), Cleveland Clinic; University of Sydney (S.J.G.L.); Sunnybrook Health Sciences Centre (M.M.), University of Toronto; VA Puget Sound & University of Washington (D.W.T.); University College London (Z.W.).

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http://dx.doi.org/10.1212/WNL.0000000000009323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274845PMC
April 2020

New evidence on the management of Lewy body dementia.

Lancet Neurol 2020 02 10;19(2):157-169. Epub 2019 Sep 10.

Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.

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http://dx.doi.org/10.1016/S1474-4422(19)30153-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017451PMC
February 2020

Consecutive sessions of transcranial direct current stimulation do not remediate visual hallucinations in Lewy body dementia: a randomised controlled trial.

Alzheimers Res Ther 2019 01 18;11(1). Epub 2019 Jan 18.

Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1186/s13195-018-0465-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339360PMC
January 2019

Clinical prevalence of Lewy body dementia.

Alzheimers Res Ther 2018 02 15;10(1):19. Epub 2018 Feb 15.

Institute of Neuroscience, Biomedical Research Building, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1186/s13195-018-0350-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815202PMC
February 2018

Author response: Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.

Authors:
Ian G McKeith

Neurology 2018 02;90(6):300-301

(Newcastle-Upon-Tyne, UK).

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http://dx.doi.org/10.1212/WNL.0000000000004919DOI Listing
February 2018

Neuropsychiatric symptoms and cognitive profile in mild cognitive impairment with Lewy bodies.

Psychol Med 2018 10 24;48(14):2384-2390. Epub 2018 Jan 24.

Institute for Ageing and Institute of Neuroscience,Newcastle University,Newcastle upon Tyne,UK.

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http://dx.doi.org/10.1017/S0033291717003956DOI Listing
October 2018

Regional levels of physiological α-synuclein are directly associated with Lewy body pathology.

Acta Neuropathol 2018 01 13;135(1):153-154. Epub 2017 Nov 13.

Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1007/s00401-017-1787-6DOI Listing
January 2018

Transcranial direct current stimulation in Parkinson's disease dementia: A randomised double-blind crossover trial.

Brain Stimul 2017 Nov - Dec;10(6):1150-1151. Epub 2017 Jul 31.

Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1016/j.brs.2017.07.012DOI Listing
July 2017

Symptoms associated with Lewy body disease in mild cognitive impairment.

Int J Geriatr Psychiatry 2017 Nov 29;32(11):1163-1171. Epub 2017 May 29.

Institute for Ageing and Institute of Neuroscience, Newcastle University, UK.

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http://dx.doi.org/10.1002/gps.4742DOI Listing
November 2017

Quantitative neuropathology: an update on automated methodologies and implications for large scale cohorts.

J Neural Transm (Vienna) 2017 06 6;124(6):671-683. Epub 2017 Mar 6.

Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1007/s00702-017-1702-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446847PMC
June 2017

Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies.

Am J Geriatr Psychiatry 2017 Jun 10;25(6):595-604. Epub 2017 Jan 10.

Ageing Research Laboratories, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10647481173000
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http://dx.doi.org/10.1016/j.jagp.2017.01.005DOI Listing
June 2017

Specific patterns of neuronal loss in the pulvinar nucleus in dementia with lewy bodies.

Mov Disord 2017 03 6;32(3):414-422. Epub 2017 Jan 6.

Institute of Neuroscience, Ageing Research Laboratories, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom.

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http://doi.wiley.com/10.1002/mds.26887
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http://dx.doi.org/10.1002/mds.26887DOI Listing
March 2017

TDP-43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing.

Brain Pathol 2017 07 24;27(4):472-479. Epub 2016 Aug 24.

Institute of Neuroscience, Newcastle University, Newcastle Upon Tyne, UK.

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http://dx.doi.org/10.1111/bpa.12424DOI Listing
July 2017

Cholinergic and perfusion brain networks in Parkinson disease dementia.

Neurology 2016 07 15;87(2):178-85. Epub 2016 Jun 15.

From the Institute of Neuroscience (S.J.C., I.G.M., D.J.B., J.-P.T.), Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne; SINAPSE (D.J.W.), Institute of Neuroscience and Psychology, University of Glasgow; and Department of Psychiatry (J.T.O.), University of Cambridge, UK.

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http://dx.doi.org/10.1212/WNL.0000000000002839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940066PMC
July 2016

Depressive symptoms are associated with daytime sleepiness and subjective sleep quality in dementia with Lewy bodies.

Int J Geriatr Psychiatry 2016 07 11;31(7):765-70. Epub 2015 Nov 11.

Institute of Neuroscience, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/gps.4389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949673PMC
July 2016

Resting state in Parkinson's disease dementia and dementia with Lewy bodies: commonalities and differences.

Int J Geriatr Psychiatry 2015 Nov 13;30(11):1135-46. Epub 2015 Aug 13.

Institute of Neuroscience, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/gps.4342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737212PMC
November 2015

Regional covariance of muscarinic acetylcholine receptors in Alzheimer's disease using (R, R) [(123)I]-QNB SPECT.

J Neurol 2015 Sep 30;262(9):2144-53. Epub 2015 Jun 30.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK.

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http://dx.doi.org/10.1007/s00415-015-7827-zDOI Listing
September 2015

Clinicians' ability to diagnose dementia with Lewy bodies is not affected by β-amyloid load.

Neurology 2015 Feb 31;84(5):496-9. Epub 2014 Dec 31.

From the Division of Neurology V and Neuropathology (P.T.), IRCCS Foundation, Carlo Besta Neurologic Institute, Milan, Italy; Institute for Aging and Health (J.A., A.T., A.B., E.J., D.J.L., R.H.P., L.R., L.W., I.G.M.), Wolfson Research Center, Campus for Aging and Vitality, Newcastle University, Newcastle upon Tyne, UK; and Division of Neurology and Neurophysiology (M.O.), Azienda Ospedaliera di Busto Arsizio, Presidio di Tradate, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000001204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336072PMC
February 2015

The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis.

Alzheimers Res Ther 2014 21;6(4):46. Epub 2014 Jul 21.

Level 3, Biomedical Research Building, Institute for Ageing and Health, Campus for Ageing and Vitality, Newcastle University, Newcastle NE4 5PL, UK.

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http://dx.doi.org/10.1186/alzrt274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255387PMC
December 2014

Frontotemporal dementia and its subtypes: a genome-wide association study.

Authors:
Raffaele Ferrari Dena G Hernandez Michael A Nalls Jonathan D Rohrer Adaikalavan Ramasamy John B J Kwok Carol Dobson-Stone William S Brooks Peter R Schofield Glenda M Halliday John R Hodges Olivier Piguet Lauren Bartley Elizabeth Thompson Eric Haan Isabel Hernández Agustín Ruiz Mercè Boada Barbara Borroni Alessandro Padovani Carlos Cruchaga Nigel J Cairns Luisa Benussi Giuliano Binetti Roberta Ghidoni Gianluigi Forloni Daniela Galimberti Chiara Fenoglio Maria Serpente Elio Scarpini Jordi Clarimón Alberto Lleó Rafael Blesa Maria Landqvist Waldö Karin Nilsson Christer Nilsson Ian R A Mackenzie Ging-Yuek R Hsiung David M A Mann Jordan Grafman Christopher M Morris Johannes Attems Timothy D Griffiths Ian G McKeith Alan J Thomas P Pietrini Edward D Huey Eric M Wassermann Atik Baborie Evelyn Jaros Michael C Tierney Pau Pastor Cristina Razquin Sara Ortega-Cubero Elena Alonso Robert Perneczky Janine Diehl-Schmid Panagiotis Alexopoulos Alexander Kurz Innocenzo Rainero Elisa Rubino Lorenzo Pinessi Ekaterina Rogaeva Peter St George-Hyslop Giacomina Rossi Fabrizio Tagliavini Giorgio Giaccone James B Rowe Johannes C M Schlachetzki James Uphill John Collinge Simon Mead Adrian Danek Vivianna M Van Deerlin Murray Grossman John Q Trojanowski Julie van der Zee William Deschamps Tim Van Langenhove Marc Cruts Christine Van Broeckhoven Stefano F Cappa Isabelle Le Ber Didier Hannequin Véronique Golfier Martine Vercelletto Alexis Brice Benedetta Nacmias Sandro Sorbi Silvia Bagnoli Irene Piaceri Jørgen E Nielsen Lena E Hjermind Matthias Riemenschneider Manuel Mayhaus Bernd Ibach Gilles Gasparoni Sabrina Pichler Wei Gu Martin N Rossor Nick C Fox Jason D Warren Maria Grazia Spillantini Huw R Morris Patrizia Rizzu Peter Heutink Julie S Snowden Sara Rollinson Anna Richardson Alexander Gerhard Amalia C Bruni Raffaele Maletta Francesca Frangipane Chiara Cupidi Livia Bernardi Maria Anfossi Maura Gallo Maria Elena Conidi Nicoletta Smirne Rosa Rademakers Matt Baker Dennis W Dickson Neill R Graff-Radford Ronald C Petersen David Knopman Keith A Josephs Bradley F Boeve Joseph E Parisi William W Seeley Bruce L Miller Anna M Karydas Howard Rosen John C van Swieten Elise G P Dopper Harro Seelaar Yolande A L Pijnenburg Philip Scheltens Giancarlo Logroscino Rosa Capozzo Valeria Novelli Annibale A Puca Massimo Franceschi Alfredo Postiglione Graziella Milan Paolo Sorrentino Mark Kristiansen Huei-Hsin Chiang Caroline Graff Florence Pasquier Adeline Rollin Vincent Deramecourt Florence Lebert Dimitrios Kapogiannis Luigi Ferrucci Stuart Pickering-Brown Andrew B Singleton John Hardy Parastoo Momeni

Lancet Neurol 2014 Jul;13(7):686-99

Laboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Science Center, Lubbock, Texas, USA.

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http://dx.doi.org/10.1016/S1474-4422(14)70065-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112126PMC
July 2014

Covariant perfusion patterns provide clues to the origin of cognitive fluctuations and attentional dysfunction in dementia with Lewy bodies.

Int Psychogeriatr 2013 Dec 23;25(12):1917-28. Epub 2013 Oct 23.

Institute for Ageing and Health, Campus for Aging and Vitality, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1017/S1041610213001488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819183PMC
December 2013

Decreased immunoreactivities of neocortical AMPA receptor subunits correlate with motor disability in Lewy body dementias.

J Neural Transm (Vienna) 2014 Jan 12;121(1):71-8. Epub 2013 Jul 12.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore, 117597, Singapore.

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http://dx.doi.org/10.1007/s00702-013-1067-0DOI Listing
January 2014

Distinct cognitive phenotypes in Alzheimer's disease in older people.

Int Psychogeriatr 2013 Oct 5;25(10):1659-66. Epub 2013 Jul 5.

Department of Older Peoples Medicine, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, High Heaton, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1017/S1041610213000914DOI Listing
October 2013

Multivariate spatial covariance analysis of 99mTc-exametazime SPECT images in dementia with Lewy bodies and Alzheimer's disease: utility in differential diagnosis.

J Cereb Blood Flow Metab 2013 Apr 30;33(4):612-8. Epub 2013 Jan 30.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1038/jcbfm.2013.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618400PMC
April 2013

Cognitive decline and dementia risk in older adults with psychotic symptoms: a prospective cohort study.

Am J Geriatr Psychiatry 2013 Feb 22;21(2):119-28. Epub 2013 Jan 22.

School for Mental Health and Neuroscience and Alzheimer Centre Limburg, Maastricht University Medical Centre, The Netherlands.

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http://dx.doi.org/10.1016/j.jagp.2012.10.010DOI Listing
February 2013

Synaptic proteins and choline acetyltransferase loss in visual cortex in dementia with Lewy bodies.

J Neuropathol Exp Neurol 2013 Jan;72(1):53-60

Institute for Ageing and Health, Wolfson Research Centre, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1097/NEN.0b013e31827c5710DOI Listing
January 2013

The assessment of cognition in visually impaired older adults.

Age Ageing 2013 Jan 28;42(1):98-102. Epub 2012 Oct 28.

Newcastle University - Institute for Ageing and Health, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1093/ageing/afs157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153986PMC
January 2013

Glucocerebrosidase mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease.

J Neurochem 2012 Oct 22;123(2):298-309. Epub 2012 Aug 22.

Medical Toxicology Centre, Wolfson Building, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07879.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494984PMC
October 2012

Supporting clinical research in the NHS in England: the National Institute for Health Research Dementias and Neurodegenerative Diseases Research Network.

Alzheimers Res Ther 2012 6;4(4):23. Epub 2012 Jul 6.

Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London WC1N 3BG, UK.

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http://dx.doi.org/10.1186/alzrt126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506937PMC
June 2014

Frontotemporal dementia in elderly individuals.

Arch Neurol 2012 Aug;69(8):1052-60

Department of Neuropathology, Walton Centre for Neurology and Neurosurgery, Liverpool, England, UK.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archneurol.2011.3323DOI Listing
August 2012

Visual cortex in dementia with Lewy bodies: magnetic resonance imaging study.

Br J Psychiatry 2012 Jun 12;200(6):491-8. Epub 2012 Apr 12.

Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Campus for Ageing and Vitality, UK.

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http://dx.doi.org/10.1192/bjp.bp.111.099432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365275PMC
June 2012

Relationship between mitochondria and α-synuclein: a study of single substantia nigra neurons.

Arch Neurol 2012 Mar;69(3):385-93

Mitochondrial Research Group, Institute of Ageing and Health, The Medical School, Newcastle University, Newcastle upon Tyne, England.

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http://dx.doi.org/10.1001/archneurol.2011.2675DOI Listing
March 2012

Impact of less common and "disregarded" neurodegenerative pathologies on dementia burden in a population-based cohort.

J Alzheimers Dis 2012 ;28(2):485-93

Cognitive Neuroscience Laboratory, School of Psychology, Social Work and Social Policy, University of South Australia, SA, Australia.

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http://dx.doi.org/10.3233/JAD-2011-111268DOI Listing
May 2012

Visual hallucinations in dementia with Lewy bodies: transcranial magnetic stimulation study.

Br J Psychiatry 2011 Dec 20;199(6):492-500. Epub 2011 Oct 20.

Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK.

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http://dx.doi.org/10.1192/bjp.bp.110.090373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227808PMC
December 2011

Neuropathological profile of mild cognitive impairment from a population perspective.

Alzheimer Dis Assoc Disord 2012 Jul-Sep;26(3):205-12

Department of Public Health and Primary Care, Institute of Public Health, Cambridge University, Cambridge, UK.

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http://dx.doi.org/10.1097/WAD.0b013e31822fc24dDOI Listing
January 2013

Plasma homocysteine and cognitive decline in older hypertensive subjects.

Int Psychogeriatr 2011 Dec 6;23(10):1607-15. Epub 2011 May 6.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1017/S1041610211000779DOI Listing
December 2011

Optimizing mild cognitive impairment for discriminating dementia risk in the general older population.

Am J Geriatr Psychiatry 2010 Aug;18(8):662-73

Department of Public Health and Primary Care, Institute of Public Health, Cambridge, UK.

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http://dx.doi.org/10.1097/jgp.0b013e3181e0450dDOI Listing
August 2010

Nicotinic 123I-5IA-85380 single photon emission computed tomography as a predictor of cognitive progression in Alzheimer's disease and dementia with Lewy bodies.

Am J Geriatr Psychiatry 2010 Jan;18(1):86-90

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1097/JGP.0b013e3181b972aaDOI Listing
January 2010

Covariance 99mTc-exametazime SPECT patterns in Alzheimer's disease and dementia with Lewy bodies: utility in differential diagnosis.

J Geriatr Psychiatry Neurol 2010 Mar 22;23(1):54-62. Epub 2009 Dec 22.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle Upon Tyne, United Kingdom.

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http://dx.doi.org/10.1177/0891988709355272DOI Listing
March 2010

Levodopa use and sleep in patients with dementia with Lewy bodies.

Mov Disord 2009 Mar;24(4):609-12

Wolfson Research Centre, Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom.

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http://doi.wiley.com/10.1002/mds.22411
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http://dx.doi.org/10.1002/mds.22411DOI Listing
March 2009

Diagnostic accuracy of 123I-FP-CIT SPECT in possible dementia with Lewy bodies.

Br J Psychiatry 2009 Jan;194(1):34-9

Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1192/bjp.bp.108.052050DOI Listing
January 2009

A comparison of 99mTc-exametazime and 123I-FP-CIT SPECT imaging in the differential diagnosis of Alzheimer's disease and dementia with Lewy bodies.

Int Psychogeriatr 2008 Dec 27;20(6):1124-40. Epub 2008 Aug 27.

Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1017/S1041610208007709DOI Listing
December 2008

Two-year progression from mild cognitive impairment to dementia: to what extent do different definitions agree?

J Am Geriatr Soc 2008 Aug 24;56(8):1424-33. Epub 2008 Jul 24.

Medical Resarch Council Biostatistics Unit, Institute of Public Health, Cambridge, United Kindom.

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http://dx.doi.org/10.1111/j.1532-5415.2008.01820.xDOI Listing
August 2008

Mild cognitive impairment in the older population: Who is missed and does it matter?

Int J Geriatr Psychiatry 2008 Aug;23(8):863-71

Department of Public Health and Primary Care, Institute of Public Health, Cambridge UK.

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http://dx.doi.org/10.1002/gps.2013DOI Listing
August 2008

Nicotinic alpha4beta2 receptor binding in dementia with Lewy bodies using 123I-5IA-85380 SPECT demonstrates a link between occipital changes and visual hallucinations.

Neuroimage 2008 Apr 19;40(3):1056-63. Epub 2008 Jan 19.

Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2008.01.010DOI Listing
April 2008

Early cognitive change in the general population: how do different definitions work?

J Am Geriatr Soc 2007 Oct;55(10):1534-40

Department of Public Health and Primary Care, Institute of Public Health, Cambridge, United Kingdom.

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http://dx.doi.org/10.1111/j.1532-5415.2007.01386.xDOI Listing
October 2007

Selective loss of dopamine D2 receptors in temporal cortex in dementia with Lewy bodies, association with cognitive decline.

Synapse 2007 Nov;61(11):903-11

Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Newcastle-upon-Tyne NE4 6BE, United Kingdom.

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http://dx.doi.org/10.1002/syn.20441DOI Listing
November 2007

Muscarinic acetylcholine receptor status in Alzheimer's disease assessed using (R, R) 123I-QNB SPECT.

J Neurol 2007 Jul 14;254(7):907-13. Epub 2007 Mar 14.

Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK.

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http://dx.doi.org/10.1007/s00415-006-0473-8DOI Listing
July 2007

Cholinesterase inhibitor use does not significantly influence the ability of 123I-FP-CIT imaging to distinguish Alzheimer's disease from dementia with Lewy bodies.

J Neurol Neurosurg Psychiatry 2007 Oct 13;78(10):1069-71. Epub 2007 Feb 13.

Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK.

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http://dx.doi.org/10.1136/jnnp.2006.111666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117542PMC
October 2007

Effects of donepezil on central processing speed and attentional measures in Parkinson's disease with dementia and dementia with Lewy bodies.

Dement Geriatr Cogn Disord 2007 28;23(3):161-7. Epub 2006 Dec 28.

Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1159/000098335DOI Listing
April 2007

Progression of white matter hyperintensities in Alzheimer disease, dementia with lewy bodies, and Parkinson disease dementia: a comparison with normal aging.

Am J Geriatr Psychiatry 2006 Oct;14(10):842-9

Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1097/01.JGP.0000236596.56982.1cDOI Listing
October 2006

In vivo SPECT imaging of muscarinic acetylcholine receptors using (R,R) 123I-QNB in dementia with Lewy bodies and Parkinson's disease dementia.

Neuroimage 2006 Nov 7;33(2):423-9. Epub 2006 Sep 7.

Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2006.07.026DOI Listing
November 2006

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop.

Authors:
Ian G McKeith

J Alzheimers Dis 2006 ;9(3 Suppl):417-23

Wolfson Research Centre, Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, NE4 6BE, UK.

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http://dx.doi.org/10.3233/jad-2006-9s347DOI Listing
October 2006

Cholinesterase inhibitors in advanced Dementia with Lewy bodies: increase or stop?

Int J Geriatr Psychiatry 2006 Aug;21(8):719-21

Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/gps.1547DOI Listing
August 2006

Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation.

Neurobiol Dis 2006 Aug 8;23(2):481-9. Epub 2006 Jun 8.

CNR, Institute of Neuroscience, Cellular and Molecular Pharmacology Section, Department of Medical Pharmacology and Center of Excellence on Neurodegenerative Diseases, University of Milan, Italy.

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http://dx.doi.org/10.1016/j.nbd.2006.04.005DOI Listing
August 2006

Characteristics of visual hallucinations in Parkinson disease dementia and dementia with lewy bodies.

Am J Geriatr Psychiatry 2006 Feb;14(2):153-60

Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1097/01.JGP.0000192480.89813.80DOI Listing
February 2006

Thalamic D2 receptors in dementia with Lewy bodies, Parkinson's disease, and Parkinson's disease dementia.

Int J Neuropsychopharmacol 2007 Apr 1;10(2):231-44. Epub 2006 Feb 1.

IAH Research Laboratories, Institute for Ageing and Health, University of Newcastle-upon-Tyne, Newcastle General Hospital, Westgate Road, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1017/S146114570600647XDOI Listing
April 2007

Pathophysiology of synuclein aggregation in Lewy body disease.

Mech Ageing Dev 2006 Feb 16;127(2):188-202. Epub 2005 Nov 16.

Institute for Ageing and Health, University of Newcastle, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK.

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http://dx.doi.org/10.1016/j.mad.2005.09.014DOI Listing
February 2006

A comparison of the efficacy of donepezil in Parkinson's disease with dementia and dementia with Lewy bodies.

Int J Geriatr Psychiatry 2005 Oct;20(10):938-44

Institute for Ageing and Health, University of Newcastle upon Tyne, Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/gps.1381DOI Listing
October 2005

APOA1 polymorphism influences risk for early-onset nonfamiliar AD.

Ann Neurol 2005 Sep;58(3):436-41

Department of Psychiatry, University of Bonn, Bonn, Germany.

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http://dx.doi.org/10.1002/ana.20593DOI Listing
September 2005

Brain atrophy rates in Parkinson's disease with and without dementia using serial magnetic resonance imaging.

Mov Disord 2005 Dec;20(12):1571-6

Institute for Ageing and Health, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/mds.20652DOI Listing
December 2005

Longitudinal study of cerebral blood flow SPECT in Parkinson's disease with dementia, and dementia with Lewy bodies.

Int J Geriatr Psychiatry 2005 Aug;20(8):776-82

The Institute for Ageing and Health, University of Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/gps.1359DOI Listing
August 2005

Change in perfusion, hallucinations and fluctuations in consciousness in dementia with Lewy bodies.

Psychiatry Res 2005 Jul;139(2):79-88

Institute for Ageing and Health, University of Newcastle upon Tyne, Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK.

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http://dx.doi.org/10.1016/j.pscychresns.2005.04.002DOI Listing
July 2005

Progression of dopaminergic degeneration in dementia with Lewy bodies and Parkinson's disease with and without dementia assessed using 123I-FP-CIT SPECT.

Eur J Nucl Med Mol Imaging 2005 Oct 2;32(10):1176-85. Epub 2005 Jun 2.

Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Newcastle University, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK.

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http://dx.doi.org/10.1007/s00259-005-1830-zDOI Listing
October 2005

Muscarinic M2 and M4 receptors in anterior cingulate cortex: relation to neuropsychiatric symptoms in dementia with Lewy bodies.

Behav Brain Res 2005 Jun 21;161(2):299-305. Epub 2005 Mar 21.

Institute for Ageing and Health, MRC Building, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE46BE, UK.

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http://dx.doi.org/10.1016/j.bbr.2005.02.019DOI Listing
June 2005

Lewy body disease: thalamic cholinergic activity related to dementia and parkinsonism.

Neurobiol Aging 2006 Mar;27(3):433-8

Institute for Ageing and Health, MRC Building, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2005.02.004DOI Listing
March 2006

Neuroleptic sensitivity in Parkinson's disease and parkinsonian dementias.

J Clin Psychiatry 2005 May;66(5):633-7

Section of Geriatric Psychiatry, Central Hospital, Rogaland, Stavanger, Norway.

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May 2005

Saccadic eye movement changes in Parkinson's disease dementia and dementia with Lewy bodies.

Brain 2005 Jun 17;128(Pt 6):1267-76. Epub 2005 Mar 17.

Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, UK.

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http://brain.oxfordjournals.org/content/brain/128/6/1267.ful
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June 2005

The application of statistical parametric mapping to 123I-FP-CIT SPECT in dementia with Lewy bodies, Alzheimer's disease and Parkinson's disease.

Neuroimage 2004 Nov;23(3):956-66

Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Newcastle General Hospital, Westgate Road, Newcastle- upon-Tyne NE4 6BE, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2004.06.045DOI Listing
November 2004

Comparing gray matter loss profiles between dementia with Lewy bodies and Alzheimer's disease using cortical pattern matching: diagnosis and gender effects.

Neuroimage 2004 Sep;23(1):325-35

Laboratory of NeuroImaging, Department of Neurology, David Geffen UCLA School of Medicine, Los Angeles, CA 90095-1769, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2004.04.026DOI Listing
September 2004

Role of cholinesterase inhibitors in Parkinson's disease and dementia with Lewy bodies.

J Geriatr Psychiatry Neurol 2004 Sep;17(3):164-71

Rogaland Central Hospital, Psychiatric Clinic, PO Box 1163, Hillevaag, 4095 Stavanger, Norway.

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http://dx.doi.org/10.1177/0891988704267463DOI Listing
September 2004