Publications by authors named "Ian Dunham"

83Publications

The open targets post-GWAS analysis pipeline.

Bioinformatics 2020 May;36(9):2936-2937

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

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http://dx.doi.org/10.1093/bioinformatics/btaa020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203748PMC
May 2020

Ten simple rules for delivering live distance training in bioinformatics across the globe using webinars.

PLoS Comput Biol 2018 11 15;14(11):e1006419. Epub 2018 Nov 15.

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom.

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http://dx.plos.org/10.1371/journal.pcbi.1006419
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http://dx.doi.org/10.1371/journal.pcbi.1006419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237289PMC
November 2018

The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers.

Nat Rev Cancer 2018 11;18(11):696-705

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/s41568-018-0060-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450507PMC
November 2018

Uncovering new disease indications for G-protein coupled receptors and their endogenous ligands.

BMC Bioinformatics 2018 Oct 1;19(1):345. Epub 2018 Oct 1.

Computational Biology, Target Sciences, GlaxoSmithKline, Collegeville, PA, 19426, USA.

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https://bmcbioinformatics.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12859-018-2392-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167889PMC
October 2018

Human genes: Time to follow the roads less traveled?

Authors:
Ian Dunham

PLoS Biol 2018 09 26;16(9):e3000034. Epub 2018 Sep 26.

Open Targets and European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.3000034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175530PMC
September 2018

Designing an intuitive web application for drug discovery scientists.

Drug Discov Today 2018 06 11;23(6):1169-1174. Epub 2018 Jan 11.

Open Targets, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK; European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

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http://dx.doi.org/10.1016/j.drudis.2018.01.032DOI Listing
June 2018

Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer.

Cancer Res 2018 02 11;78(3):769-780. Epub 2017 Dec 11.

European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522379PMC
February 2018

Uncovering novel repositioning opportunities using the Open Targets platform.

Drug Discov Today 2017 12 14;22(12):1800-1807. Epub 2017 Sep 14.

GSK, Medicines Research Center, Gunnels Wood Road, Stevenage SG1 2NY, UK; Open Targets, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2017.09.007DOI Listing
December 2017

In silico prediction of novel therapeutic targets using gene-disease association data.

J Transl Med 2017 08 29;15(1):182. Epub 2017 Aug 29.

Computational Biology and Stats, Target Sciences, GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, SG1 2NY, UK.

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http://dx.doi.org/10.1186/s12967-017-1285-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576250PMC
August 2017

Literature evidence in open targets - a target validation platform.

J Biomed Semantics 2017 Jun 6;8(1):20. Epub 2017 Jun 6.

European Molecular Biology Laboratory (EMBL-EBI), European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, UK.

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http://dx.doi.org/10.1186/s13326-017-0131-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461726PMC
June 2017

Linking rare and common disease: mapping clinical disease-phenotypes to ontologies in therapeutic target validation.

J Biomed Semantics 2016 23;7. Epub 2016 Mar 23.

European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD UK ; Centre for Therapeutic Target Validation, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD UK.

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http://dx.doi.org/10.1186/s13326-016-0051-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804633PMC
October 2016

Ensembl regulation resources.

Database (Oxford) 2016 17;2016. Epub 2016 Feb 17.

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1093/database/bav119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756621PMC
October 2016

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Authors:
Kyle J Gaulton Teresa Ferreira Yeji Lee Anne Raimondo Reedik Mägi Michael E Reschen Anubha Mahajan Adam Locke N William Rayner Neil Robertson Robert A Scott Inga Prokopenko Laura J Scott Todd Green Thomas Sparso Dorothee Thuillier Loic Yengo Harald Grallert Simone Wahl Mattias Frånberg Rona J Strawbridge Hans Kestler Himanshu Chheda Lewin Eisele Stefan Gustafsson Valgerdur Steinthorsdottir Gudmar Thorleifsson Lu Qi Lennart C Karssen Elisabeth M van Leeuwen Sara M Willems Man Li Han Chen Christian Fuchsberger Phoenix Kwan Clement Ma Michael Linderman Yingchang Lu Soren K Thomsen Jana K Rundle Nicola L Beer Martijn van de Bunt Anil Chalisey Hyun Min Kang Benjamin F Voight Gonçalo R Abecasis Peter Almgren Damiano Baldassarre Beverley Balkau Rafn Benediktsson Matthias Blüher Heiner Boeing Lori L Bonnycastle Erwin P Bottinger Noël P Burtt Jason Carey Guillaume Charpentier Peter S Chines Marilyn C Cornelis David J Couper Andrew T Crenshaw Rob M van Dam Alex S F Doney Mozhgan Dorkhan Sarah Edkins Johan G Eriksson Tonu Esko Elodie Eury João Fadista Jason Flannick Pierre Fontanillas Caroline Fox Paul W Franks Karl Gertow Christian Gieger Bruna Gigante Omri Gottesman George B Grant Niels Grarup Christopher J Groves Maija Hassinen Christian T Have Christian Herder Oddgeir L Holmen Astradur B Hreidarsson Steve E Humphries David J Hunter Anne U Jackson Anna Jonsson Marit E Jørgensen Torben Jørgensen Wen-Hong L Kao Nicola D Kerrison Leena Kinnunen Norman Klopp Augustine Kong Peter Kovacs Peter Kraft Jasmina Kravic Cordelia Langford Karin Leander Liming Liang Peter Lichtner Cecilia M Lindgren Eero Lindholm Allan Linneberg Ching-Ti Liu Stéphane Lobbens Jian'an Luan Valeriya Lyssenko Satu Männistö Olga McLeod Julia Meyer Evelin Mihailov Ghazala Mirza Thomas W Mühleisen Martina Müller-Nurasyid Carmen Navarro Markus M Nöthen Nikolay N Oskolkov Katharine R Owen Domenico Palli Sonali Pechlivanis Leena Peltonen John R B Perry Carl G P Platou Michael Roden Douglas Ruderfer Denis Rybin Yvonne T van der Schouw Bengt Sennblad Gunnar Sigurðsson Alena Stančáková Gerald Steinbach Petter Storm Konstantin Strauch Heather M Stringham Qi Sun Barbara Thorand Emmi Tikkanen Anke Tonjes Joseph Trakalo Elena Tremoli Tiinamaija Tuomi Roman Wennauer Steven Wiltshire Andrew R Wood Eleftheria Zeggini Ian Dunham Ewan Birney Lorenzo Pasquali Jorge Ferrer Ruth J F Loos Josée Dupuis Jose C Florez Eric Boerwinkle James S Pankow Cornelia van Duijn Eric Sijbrands James B Meigs Frank B Hu Unnur Thorsteinsdottir Kari Stefansson Timo A Lakka Rainer Rauramaa Michael Stumvoll Nancy L Pedersen Lars Lind Sirkka M Keinanen-Kiukaanniemi Eeva Korpi-Hyövälti Timo E Saaristo Juha Saltevo Johanna Kuusisto Markku Laakso Andres Metspalu Raimund Erbel Karl-Heinz Jöcke Susanne Moebus Samuli Ripatti Veikko Salomaa Erik Ingelsson Bernhard O Boehm Richard N Bergman Francis S Collins Karen L Mohlke Heikki Koistinen Jaakko Tuomilehto Kristian Hveem Inger Njølstad Panagiotis Deloukas Peter J Donnelly Timothy M Frayling Andrew T Hattersley Ulf de Faire Anders Hamsten Thomas Illig Annette Peters Stephane Cauchi Rob Sladek Philippe Froguel Torben Hansen Oluf Pedersen Andrew D Morris Collin N A Palmer Sekar Kathiresan Olle Melander Peter M Nilsson Leif C Groop Inês Barroso Claudia Langenberg Nicholas J Wareham Christopher A O'Callaghan Anna L Gloyn David Altshuler Michael Boehnke Tanya M Teslovich Mark I McCarthy Andrew P Morris

Nat Genet 2015 Dec 9;47(12):1415-25. Epub 2015 Nov 9.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666734PMC
December 2015

Using human genetics to make new medicines.

Nat Rev Genet 2015 10 15;16(10):561-2. Epub 2015 Sep 15.

European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

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http://dx.doi.org/10.1038/nrg3998DOI Listing
October 2015

Where Next for Genetics and Genomics?

PLoS Biol 2015 Jul 30;13(7):e1002216. Epub 2015 Jul 30.

The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1002216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520474PMC
July 2015

Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association.

PLoS Genet 2014 Nov 20;10(11):e1004798. Epub 2014 Nov 20.

The European Molecular Biology Laboratory, The European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238955PMC
November 2014

Functional annotation of noncoding sequence variants.

Nat Methods 2014 Mar 2;11(3):294-6. Epub 2014 Feb 2.

1] European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, Cambridge, UK. [2] Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/nmeth.2832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015703PMC
March 2014

Genome-wide meta-analysis identifies new susceptibility loci for migraine.

Authors:
Verneri Anttila Bendik S Winsvold Padhraig Gormley Tobias Kurth Francesco Bettella George McMahon Mikko Kallela Rainer Malik Boukje de Vries Gisela Terwindt Sarah E Medland Unda Todt Wendy L McArdle Lydia Quaye Markku Koiranen M Arfan Ikram Terho Lehtimäki Anine H Stam Lannie Ligthart Juho Wedenoja Ian Dunham Benjamin M Neale Priit Palta Eija Hamalainen Markus Schürks Lynda M Rose Julie E Buring Paul M Ridker Stacy Steinberg Hreinn Stefansson Finnbogi Jakobsson Debbie A Lawlor David M Evans Susan M Ring Markus Färkkilä Ville Artto Mari A Kaunisto Tobias Freilinger Jean Schoenen Rune R Frants Nadine Pelzer Claudia M Weller Ronald Zielman Andrew C Heath Pamela A F Madden Grant W Montgomery Nicholas G Martin Guntram Borck Hartmut Göbel Axel Heinze Katja Heinze-Kuhn Frances M K Williams Anna-Liisa Hartikainen Anneli Pouta Joyce van den Ende Andre G Uitterlinden Albert Hofman Najaf Amin Jouke-Jan Hottenga Jacqueline M Vink Kauko Heikkilä Michael Alexander Bertram Muller-Myhsok Stefan Schreiber Thomas Meitinger Heinz Erich Wichmann Arpo Aromaa Johan G Eriksson Bryan Traynor Daniah Trabzuni Elizabeth Rossin Kasper Lage Suzanne B R Jacobs J Raphael Gibbs Ewan Birney Jaakko Kaprio Brenda W Penninx Dorret I Boomsma Cornelia van Duijn Olli Raitakari Marjo-Riitta Jarvelin John-Anker Zwart Lynn Cherkas David P Strachan Christian Kubisch Michel D Ferrari Arn M J M van den Maagdenberg Martin Dichgans Maija Wessman George Davey Smith Kari Stefansson Mark J Daly Dale R Nyholt Daniel Chasman Aarno Palotie

Nat Genet 2013 Aug 23;45(8):912-917. Epub 2013 Jun 23.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.2676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041123PMC
August 2013

High-resolution analysis of cis-acting regulatory networks at the α-globin locus.

Philos Trans R Soc Lond B Biol Sci 2013 6;368(1620):20120361. Epub 2013 May 6.

MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.1098/rstb.2012.0361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682726PMC
December 2013

Hes6 is required for actin cytoskeletal organization in differentiating C2C12 myoblasts.

Exp Cell Res 2011 Jul 9;317(11):1590-602. Epub 2011 Apr 9.

MRC Cancer Cell Unit, Hutchison-MRC Research Centre, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1016/j.yexcr.2011.03.023DOI Listing
July 2011

Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene.

Nucleic Acids Res 2010 Jul 31;38(13):4325-36. Epub 2010 Mar 31.

Program in Gene Function and Expression and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605-0103, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910055PMC
July 2010

Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis.

BMC Genomics 2010 Mar 15;11:175. Epub 2010 Mar 15.

Work performed at: Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-11-175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996961PMC
March 2010

DNA methylation-histone modification relationships across the desmin locus in human primary cells.

BMC Mol Biol 2009 May 27;10:51. Epub 2009 May 27.

Nuclear Biology Group, King's College London School of Medicine, Department of Medical and Molecular Genetics, 8th Floor Tower Wing, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1186/1471-2199-10-51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695444PMC
May 2009

Applications of high-throughput sequencing to chromatin structure and function in mammals.

Authors:
Ian Dunham

F1000 Biol Rep 2009 Apr 29;1:32. Epub 2009 Apr 29.

EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton Cambridge CB10 1SD UK.

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http://dx.doi.org/10.3410/B1-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924703PMC
April 2009

Evidence that replication-associated mutation alone does not explain between-chromosome differences in substitution rates.

Genome Biol Evol 2009 Apr 30;1:13-22. Epub 2009 Apr 30.

Department of Biology and Biochemistry, University of Bath, Bath, Somerset, United Kingdom.

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http://dx.doi.org/10.1093/gbe/evp001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817397PMC
April 2009

Epigenomics at the tipping point. Foreword.

Pharmacogenomics 2008 Dec;9(12):1781-3

Deptartment of Genome Sciences, University of Washington, Foege S310A, 1705 NE Pacific Street, Box 355065, Seattle WA 98195, USA.

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http://dx.doi.org/10.2217/14622416.9.12.1781DOI Listing
December 2008

The role of the polycomb complex in silencing alpha-globin gene expression in nonerythroid cells.

Blood 2008 Nov 8;112(9):3889-99. Epub 2008 Aug 8.

Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1182/blood-2008-06-161901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572806PMC
November 2008

The characteristics of human genes: analysis of human chromosome 22.

Comp Funct Genomics 2003 ;4(6):635-46

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1002/cfg.335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447302PMC
June 2010

Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians.

Nat Genet 2008 Aug 29;40(8):971-6. Epub 2008 Jun 29.

The Babraham Institute, Laboratory of Developmental Genetics and Imprinting, Cambridge CB22 3AT, UK.

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http://dx.doi.org/10.1038/ng.168DOI Listing
August 2008

Finishing the finished human chromosome 22 sequence.

Genome Biol 2008 13;9(5):R78. Epub 2008 May 13.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1186/gb-2008-9-5-r78DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441464PMC
July 2008

Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells.

Stem Cells 2008 May 21;26(5):1174-85. Epub 2008 Feb 21.

North East Institute for Stem Cell Research, University of Newcastle upon Tyne, International Centre for Life, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1634/stemcells.2007-0497DOI Listing
May 2008

A systematic library for comprehensive overexpression screens in Saccharomyces cerevisiae.

Nat Methods 2008 Mar 3;5(3):239-41. Epub 2008 Feb 3.

Department of Molecular Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nmeth.1181DOI Listing
March 2008

Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.

Blood 2007 Dec 22;110(13):4503-10. Epub 2007 Aug 22.

Medical Research Council, Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1182/blood-2007-06-097964DOI Listing
December 2007

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:
Ewan Birney John A Stamatoyannopoulos Anindya Dutta Roderic Guigó Thomas R Gingeras Elliott H Margulies Zhiping Weng Michael Snyder Emmanouil T Dermitzakis Robert E Thurman Michael S Kuehn Christopher M Taylor Shane Neph Christoph M Koch Saurabh Asthana Ankit Malhotra Ivan Adzhubei Jason A Greenbaum Robert M Andrews Paul Flicek Patrick J Boyle Hua Cao Nigel P Carter Gayle K Clelland Sean Davis Nathan Day Pawandeep Dhami Shane C Dillon Michael O Dorschner Heike Fiegler Paul G Giresi Jeff Goldy Michael Hawrylycz Andrew Haydock Richard Humbert Keith D James Brett E Johnson Ericka M Johnson Tristan T Frum Elizabeth R Rosenzweig Neerja Karnani Kirsten Lee Gregory C Lefebvre Patrick A Navas Fidencio Neri Stephen C J Parker Peter J Sabo Richard Sandstrom Anthony Shafer David Vetrie Molly Weaver Sarah Wilcox Man Yu Francis S Collins Job Dekker Jason D Lieb Thomas D Tullius Gregory E Crawford Shamil Sunyaev William S Noble Ian Dunham France Denoeud Alexandre Reymond Philipp Kapranov Joel Rozowsky Deyou Zheng Robert Castelo Adam Frankish Jennifer Harrow Srinka Ghosh Albin Sandelin Ivo L Hofacker Robert Baertsch Damian Keefe Sujit Dike Jill Cheng Heather A Hirsch Edward A Sekinger Julien Lagarde Josep F Abril Atif Shahab Christoph Flamm Claudia Fried Jörg Hackermüller Jana Hertel Manja Lindemeyer Kristin Missal Andrea Tanzer Stefan Washietl Jan Korbel Olof Emanuelsson Jakob S Pedersen Nancy Holroyd Ruth Taylor David Swarbreck Nicholas Matthews Mark C Dickson Daryl J Thomas Matthew T Weirauch James Gilbert Jorg Drenkow Ian Bell XiaoDong Zhao K G Srinivasan Wing-Kin Sung Hong Sain Ooi Kuo Ping Chiu Sylvain Foissac Tyler Alioto Michael Brent Lior Pachter Michael L Tress Alfonso Valencia Siew Woh Choo Chiou Yu Choo Catherine Ucla Caroline Manzano Carine Wyss Evelyn Cheung Taane G Clark James B Brown Madhavan Ganesh Sandeep Patel Hari Tammana Jacqueline Chrast Charlotte N Henrichsen Chikatoshi Kai Jun Kawai Ugrappa Nagalakshmi Jiaqian Wu Zheng Lian Jin Lian Peter Newburger Xueqing Zhang Peter Bickel John S Mattick Piero Carninci Yoshihide Hayashizaki Sherman Weissman Tim Hubbard Richard M Myers Jane Rogers Peter F Stadler Todd M Lowe Chia-Lin Wei Yijun Ruan Kevin Struhl Mark Gerstein Stylianos E Antonarakis Yutao Fu Eric D Green Ulaş Karaöz Adam Siepel James Taylor Laura A Liefer Kris A Wetterstrand Peter J Good Elise A Feingold Mark S Guyer Gregory M Cooper George Asimenos Colin N Dewey Minmei Hou Sergey Nikolaev Juan I Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham Haiyan Huang Nancy R Zhang Ian Holmes James C Mullikin Abel Ureta-Vidal Benedict Paten Michael Seringhaus Deanna Church Kate Rosenbloom W James Kent Eric A Stone Serafim Batzoglou Nick Goldman Ross C Hardison David Haussler Webb Miller Arend Sidow Nathan D Trinklein Zhengdong D Zhang Leah Barrera Rhona Stuart David C King Adam Ameur Stefan Enroth Mark C Bieda Jonghwan Kim Akshay A Bhinge Nan Jiang Jun Liu Fei Yao Vinsensius B Vega Charlie W H Lee Patrick Ng Atif Shahab Annie Yang Zarmik Moqtaderi Zhou Zhu Xiaoqin Xu Sharon Squazzo Matthew J Oberley David Inman Michael A Singer Todd A Richmond Kyle J Munn Alvaro Rada-Iglesias Ola Wallerman Jan Komorowski Joanna C Fowler Phillippe Couttet Alexander W Bruce Oliver M Dovey Peter D Ellis Cordelia F Langford David A Nix Ghia Euskirchen Stephen Hartman Alexander E Urban Peter Kraus Sara Van Calcar Nate Heintzman Tae Hoon Kim Kun Wang Chunxu Qu Gary Hon Rosa Luna Christopher K Glass M Geoff Rosenfeld Shelley Force Aldred Sara J Cooper Anason Halees Jane M Lin Hennady P Shulha Xiaoling Zhang Mousheng Xu Jaafar N S Haidar Yong Yu Yijun Ruan Vishwanath R Iyer Roland D Green Claes Wadelius Peggy J Farnham Bing Ren Rachel A Harte Angie S Hinrichs Heather Trumbower Hiram Clawson Jennifer Hillman-Jackson Ann S Zweig Kayla Smith Archana Thakkapallayil Galt Barber Robert M Kuhn Donna Karolchik Lluis Armengol Christine P Bird Paul I W de Bakker Andrew D Kern Nuria Lopez-Bigas Joel D Martin Barbara E Stranger Abigail Woodroffe Eugene Davydov Antigone Dimas Eduardo Eyras Ingileif B Hallgrímsdóttir Julian Huppert Michael C Zody Gonçalo R Abecasis Xavier Estivill Gerard G Bouffard Xiaobin Guan Nancy F Hansen Jacquelyn R Idol Valerie V B Maduro Baishali Maskeri Jennifer C McDowell Morgan Park Pamela J Thomas Alice C Young Robert W Blakesley Donna M Muzny Erica Sodergren David A Wheeler Kim C Worley Huaiyang Jiang George M Weinstock Richard A Gibbs Tina Graves Robert Fulton Elaine R Mardis Richard K Wilson Michele Clamp James Cuff Sante Gnerre David B Jaffe Jean L Chang Kerstin Lindblad-Toh Eric S Lander Maxim Koriabine Mikhail Nefedov Kazutoyo Osoegawa Yuko Yoshinaga Baoli Zhu Pieter J de Jong
June 2007

hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.

Genomics 2007 Mar 5;89(3):307-15. Epub 2007 Jan 5.

Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ygeno.2006.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647941PMC
March 2007

The portability of tagSNPs across populations: a worldwide survey.

Genome Res 2006 Mar 8;16(3):323-30. Epub 2006 Feb 8.

Unitat de Biologia Evolutiva, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1101/gr.4138406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415211PMC
March 2006

Evidence for widespread reticulate evolution within human duplicons.

Am J Hum Genet 2005 Nov 30;77(5):824-40. Epub 2005 Sep 30.

Institute of Human Genetics, University of Newcastle upon Tyne, International Centre for Life, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1086/497704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1271390PMC
November 2005

Investigating chromosome organization with genomic microarrays.

Chromosome Res 2005 ;13(3):249-57

Department of Medical and Molecular Genetics, GKT School of Medicine, King's College London, London, SE1 9RT, UK.

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http://dx.doi.org/10.1007/s10577-005-1504-5DOI Listing
August 2005

Replication timing of human chromosome 6.

2005 Jan 5;4(1):172-6. Epub 2005 Jan 5.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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https://www.tandfonline.com/doi/full/10.4161/cc.4.1.1350
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http://dx.doi.org/10.4161/cc.4.1.1350DOI Listing
January 2005

Novel microsatellite markers and single nucleotide polymorphisms refine the tylosis with oesophageal cancer (TOC) minimal region on 17q25 to 42.5 kb: sequencing does not identify the causative gene.

Hum Genet 2004 May 9;114(6):534-40. Epub 2004 Mar 9.

Molecular Genetics and Oncology Group, Department of Clinical Dental Sciences, University of Liverpool, Edward's Building, Daulby Street, L69 3GN, Liverpool, UK.

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http://dx.doi.org/10.1007/s00439-004-1100-3DOI Listing
May 2004

Replication timing of the human genome.

Hum Mol Genet 2004 Jan 25;13(2):191-202. Epub 2003 Nov 25.

The Welcome Trust Sanger Institute, Welcome Genome Campus, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/ddh016DOI Listing
January 2004

DNA rescue by the vectorette method.

Methods Mol Biol 2003 ;226:393-400

Department of Molecular Biology, Yamanochi Research Institute, Oxford, UK.

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http://dx.doi.org/10.1385/1-59259-384-4:393DOI Listing
November 2003

Reevaluating human gene annotation: a second-generation analysis of chromosome 22.

Genome Res 2003 Jan;13(1):27-36

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1101/gr.695703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC430954PMC
January 2003

Human genome sequences: enigmatic variations.

Authors:
Ian Dunham

Mutagenesis 2002 Nov;17(6):457-61

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1093/mutage/17.6.457DOI Listing
November 2002

The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer.

BMC Genet 2002 Oct 15;3:20. Epub 2002 Oct 15.

Cancer Research UK Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, OX3 9DS, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134458PMC
http://dx.doi.org/10.1186/1471-2156-3-20DOI Listing
October 2002

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.

Genomics 2002 Mar;79(3):285-96

RNA Editing Group, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, Du Cane Road, London, W12 ONN, UK.

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http://dx.doi.org/10.1006/geno.2002.6718DOI Listing
March 2002