Publications by authors named "Ian Deary"

99Publications

Birth weight associations with DNA methylation differences in an adult population.

Epigenetics 2020 Oct 20:1-14. Epub 2020 Oct 20.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh , Edinburgh, UK.

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http://dx.doi.org/10.1080/15592294.2020.1827713DOI Listing
October 2020

Dietary patterns, cognitive function, and structural neuroimaging measures of brain aging.

Exp Gerontol 2020 Oct 16:111117. Epub 2020 Oct 16.

Lothian Birth Cohorts Group, Department of Psychology, University of Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2020.111117DOI Listing
October 2020

Genome-wide association study identifies 48 common genetic variants associated with handedness.

Authors:
Gabriel Cuellar-Partida Joyce Y Tung Nicholas Eriksson Eva Albrecht Fazil Aliev Ole A Andreassen Inês Barroso Jacques S Beckmann Marco P Boks Dorret I Boomsma Heather A Boyd Monique M B Breteler Harry Campbell Daniel I Chasman Lynn F Cherkas Gail Davies Eco J C de Geus Ian J Deary Panos Deloukas Danielle M Dick David L Duffy Johan G Eriksson Tõnu Esko Bjarke Feenstra Frank Geller Christian Gieger Ina Giegling Scott D Gordon Jiali Han Thomas F Hansen Annette M Hartmann Caroline Hayward Kauko Heikkilä Andrew A Hicks Joel N Hirschhorn Jouke-Jan Hottenga Jennifer E Huffman Liang-Dar Hwang M Arfan Ikram Jaakko Kaprio John P Kemp Kay-Tee Khaw Norman Klopp Bettina Konte Zoltan Kutalik Jari Lahti Xin Li Ruth J F Loos Michelle Luciano Sigurdur H Magnusson Massimo Mangino Pedro Marques-Vidal Nicholas G Martin Wendy L McArdle Mark I McCarthy Carolina Medina-Gomez Mads Melbye Scott A Melville Andres Metspalu Lili Milani Vincent Mooser Mari Nelis Dale R Nyholt Kevin S O'Connell Roel A Ophoff Cameron Palmer Aarno Palotie Teemu Palviainen Guillaume Pare Lavinia Paternoster Leena Peltonen Brenda W J H Penninx Ozren Polasek Peter P Pramstaller Inga Prokopenko Katri Raikkonen Samuli Ripatti Fernando Rivadeneira Igor Rudan Dan Rujescu Johannes H Smit George Davey Smith Jordan W Smoller Nicole Soranzo Tim D Spector Beate St Pourcain John M Starr Hreinn Stefánsson Stacy Steinberg Maris Teder-Laving Gudmar Thorleifsson Kári Stefánsson Nicholas J Timpson André G Uitterlinden Cornelia M van Duijn Frank J A van Rooij Jaqueline M Vink Peter Vollenweider Eero Vuoksimaa Gérard Waeber Nicholas J Wareham Nicole Warrington Dawn Waterworth Thomas Werge H-Erich Wichmann Elisabeth Widen Gonneke Willemsen Alan F Wright Margaret J Wright Mousheng Xu Jing Hua Zhao Peter Kraft David A Hinds Cecilia M Lindgren Reedik Mägi Benjamin M Neale David M Evans Sarah E Medland

Nat Hum Behav 2020 Sep 28. Epub 2020 Sep 28.

The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia.

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http://dx.doi.org/10.1038/s41562-020-00956-yDOI Listing
September 2020

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.

Authors:
Edith Hofer Gennady V Roshchupkin Hieab H H Adams Maria J Knol Honghuang Lin Shuo Li Habil Zare Shahzad Ahmad Nicola J Armstrong Claudia L Satizabal Manon Bernard Joshua C Bis Nathan A Gillespie Michelle Luciano Aniket Mishra Markus Scholz Alexander Teumer Rui Xia Xueqiu Jian Thomas H Mosley Yasaman Saba Lukas Pirpamer Stephan Seiler James T Becker Owen Carmichael Jerome I Rotter Bruce M Psaty Oscar L Lopez Najaf Amin Sven J van der Lee Qiong Yang Jayandra J Himali Pauline Maillard Alexa S Beiser Charles DeCarli Sherif Karama Lindsay Lewis Mat Harris Mark E Bastin Ian J Deary A Veronica Witte Frauke Beyer Markus Loeffler Karen A Mather Peter R Schofield Anbupalam Thalamuthu John B Kwok Margaret J Wright David Ames Julian Trollor Jiyang Jiang Henry Brodaty Wei Wen Meike W Vernooij Albert Hofman André G Uitterlinden Wiro J Niessen Katharina Wittfeld Robin Bülow Uwe Völker Zdenka Pausova G Bruce Pike Sophie Maingault Fabrice Crivello Christophe Tzourio Philippe Amouyel Bernard Mazoyer Michael C Neale Carol E Franz Michael J Lyons Matthew S Panizzon Ole A Andreassen Anders M Dale Mark Logue Katrina L Grasby Neda Jahanshad Jodie N Painter Lucía Colodro-Conde Janita Bralten Derrek P Hibar Penelope A Lind Fabrizio Pizzagalli Jason L Stein Paul M Thompson Sarah E Medland Perminder S Sachdev William S Kremen Joanna M Wardlaw Arno Villringer Cornelia M van Duijn Hans J Grabe William T Longstreth Myriam Fornage Tomas Paus Stephanie Debette M Arfan Ikram Helena Schmidt Reinhold Schmidt Sudha Seshadri

Nat Commun 2020 09 22;11(1):4796. Epub 2020 Sep 22.

Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, USA.

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http://dx.doi.org/10.1038/s41467-020-18367-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508833PMC
September 2020

A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.

Nat Hum Behav 2020 Sep 7. Epub 2020 Sep 7.

Lothian Birth Cohorts, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41562-020-00936-2DOI Listing
September 2020

Aging-Sensitive Networks Within the Human Structural Connectome Are Implicated in Late-Life Cognitive Declines.

Biol Psychiatry 2020 Jun 15. Epub 2020 Jun 15.

Department of Psychology, University of Texas at Austin, Austin, Texas; Population Research Center, University of Texas at Austin, Austin, Texas.

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http://dx.doi.org/10.1016/j.biopsych.2020.06.010DOI Listing
June 2020

Blood pressure and cognitive function across the eighth decade: a prospective study of the Lothian Birth Cohort of 1936.

BMJ Open 2020 07 23;10(7):e033990. Epub 2020 Jul 23.

Department of Psychology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1136/bmjopen-2019-033990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380861PMC
July 2020

Epigenetic prediction of major depressive disorder.

Mol Psychiatry 2020 Jun 10. Epub 2020 Jun 10.

Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41380-020-0808-3DOI Listing
June 2020

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.

Stroke 2020 Jul 10;51(7):2111-2121. Epub 2020 Jun 10.

GeneSTAR Research Program (L.R.Y., B.G.K., L.C.B., P.A.N.), Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1161/STROKEAHA.119.027544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365038PMC
July 2020

Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936.

Stem Cell Res 2020 07 20;46:101851. Epub 2020 May 20.

iPSC Core, The David Janet Polak Foundation Stem Cell Core Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Cedars-Sinai Biomanufacturing Center, West Hollywood, CA 90069, USA; Board of Governors-Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2020.101851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347008PMC
July 2020

The long arm of childhood intelligence on terminal decline: Evidence from the Lothian Birth Cohort 1921.

Psychol Aging 2020 Sep 21;35(6):806-817. Epub 2020 May 21.

Centre for Dementia Prevention, University of Edinburgh.

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http://dx.doi.org/10.1037/pag0000477DOI Listing
September 2020

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.

Authors:
Lisa de Las Fuentes Yun Ju Sung Raymond Noordam Thomas Winkler Mary F Feitosa Karen Schwander Amy R Bentley Michael R Brown Xiuqing Guo Alisa Manning Daniel I Chasman Hugues Aschard Traci M Bartz Lawrence F Bielak Archie Campbell Ching-Yu Cheng Rajkumar Dorajoo Fernando P Hartwig A R V R Horimoto Changwei Li Ruifang Li-Gao Yongmei Liu Jonathan Marten Solomon K Musani Ioanna Ntalla Tuomo Rankinen Melissa Richard Xueling Sim Albert V Smith Salman M Tajuddin Bamidele O Tayo Dina Vojinovic Helen R Warren Deng Xuan Maris Alver Mathilde Boissel Jin-Fang Chai Xu Chen Kaare Christensen Jasmin Divers Evangelos Evangelou Chuan Gao Giorgia Girotto Sarah E Harris Meian He Fang-Chi Hsu Brigitte Kühnel Federica Laguzzi Xiaoyin Li Leo-Pekka Lyytikäinen Ilja M Nolte Alaitz Poveda Rainer Rauramaa Muhammad Riaz Rico Rueedi Xiao-Ou Shu Harold Snieder Tamar Sofer Fumihiko Takeuchi Niek Verweij Erin B Ware Stefan Weiss Lisa R Yanek Najaf Amin Dan E Arking Donna K Arnett Sven Bergmann Eric Boerwinkle Jennifer A Brody Ulrich Broeckel Marco Brumat Gregory Burke Claudia P Cabrera Mickaël Canouil Miao Li Chee Yii-Der Ida Chen Massimiliano Cocca John Connell H Janaka de Silva Paul S de Vries Gudny Eiriksdottir Jessica D Faul Virginia Fisher Terrence Forrester Ervin F Fox Yechiel Friedlander He Gao Bruna Gigante Franco Giulianini Chi Charles Gu Dongfeng Gu Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Steven Hunt M Arfan Ikram Marguerite R Irvin Mika Kähönen Maryam Kavousi Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Pirjo Komulainen Aldi T Kraja J E Krieger Carl D Langefeld Yize Li Jingjing Liang David C M Liewald Ching-Ti Liu Jianjun Liu Kurt K Lohman Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Dennis O Mook-Kanamori Mike A Nalls Christopher P Nelson Jill M Norris Jeff O'Connell Adesola Ogunniyi Sandosh Padmanabhan Nicholette D Palmer Nancy L Pedersen Thomas Perls Annette Peters Astrid Petersmann Patricia A Peyser Ozren Polasek David J Porteous Leslie J Raffel Treva K Rice Jerome I Rotter Igor Rudan Oscar-Leonel Rueda-Ochoa Charumathi Sabanayagam Babatunde L Salako Pamela J Schreiner James M Shikany Stephen S Sidney Mario Sims Colleen M Sitlani Jennifer A Smith John M Starr Konstantin Strauch Morris A Swertz Alexander Teumer Yih Chung Tham André G Uitterlinden Dhananjay Vaidya M Yldau van der Ende Melanie Waldenberger Lihua Wang Ya-Xing Wang Wen-Bin Wei David R Weir Wanqing Wen Jie Yao Bing Yu Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Donald W Bowden Ian J Deary Marcus Dörr Tõnu Esko Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Candace M Kammerer Norihiro Kato Timo A Lakka Karin Leander Terho Lehtimäki Patrik K E Magnusson Pedro Marques-Vidal Brenda W J H Penninx Nilesh J Samani Pim van der Harst Lynne E Wagenknecht Tangchun Wu Wei Zheng Xiaofeng Zhu Claude Bouchard Richard S Cooper Adolfo Correa Michele K Evans Vilmundur Gudnason Caroline Hayward Bernardo L Horta Tanika N Kelly Stephen B Kritchevsky Daniel Levy Walter R Palmas A C Pereira Michael M Province Bruce M Psaty Paul M Ridker Charles N Rotimi E Shyong Tai Rob M van Dam Cornelia M van Duijn Tien Yin Wong Kenneth Rice W James Gauderman Alanna C Morrison Kari E North Sharon L R Kardia Mark J Caulfield Paul Elliott Patricia B Munroe Paul W Franks Dabeeru C Rao Myriam Fornage

Mol Psychiatry 2020 May 5. Epub 2020 May 5.

Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 70808, USA.

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http://dx.doi.org/10.1038/s41380-020-0719-3DOI Listing
May 2020

Association of Childhood Psychomotor Coordination With Survival Up to 6 Decades Later.

JAMA Netw Open 2020 04 1;3(4):e204031. Epub 2020 Apr 1.

Centre for Longitudinal Studies, University College London Institute of Education, London, United Kingdom.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.4031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193332PMC
April 2020

DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health.

Alzheimers Dement (N Y) 2020 27;6(1):e12026. Epub 2020 Apr 27.

Centre for Genomic and Experimental Medicine Institute of Genetics and Molecular Medicine University of Edinburgh Edinburgh UK.

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http://dx.doi.org/10.1002/trc2.12026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185210PMC
April 2020

Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data.

Nat Commun 2020 04 28;11(1):2061. Epub 2020 Apr 28.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1038/s41467-020-15587-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188843PMC
April 2020

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples.

Genome Med 2020 04 28;12(1):39. Epub 2020 Apr 28.

Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, J. B. Winsløws Vej 9B, DK-5000, Odense C, Denmark.

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http://dx.doi.org/10.1186/s13073-020-00736-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189689PMC
April 2020

Reliability and validity of the UK Biobank cognitive tests.

PLoS One 2020 20;15(4):e0231627. Epub 2020 Apr 20.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231627PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170235PMC
July 2020

DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

Clin Epigenetics 2020 03 26;12(1):49. Epub 2020 Mar 26.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1186/s13148-020-00838-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098133PMC
March 2020

The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium.

Am J Psychiatry 2020 06 26;177(6):537-547. Epub 2020 Mar 26.

School of Psychology, Centre for Neuroimaging and Cognitive Genomics, National Centre for Biomedical Engineering Science and Galway Neuroscience Centre, National University of Ireland Galway, Galway (Holleran, Cannon, McDonald, Morris, Mothersill, Donohoe); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Kelly, Thompson, Jahanshad); Department of Psychiatry, University of Edinburgh, Edinburgh (Alloza, Lawrie); Department of Child and Adolescent Psychiatry, Instituto de Investigación Sanitaria Gregorio Marañón, IiSGM, Hospital General Universitario Gregorio Marañón, School of Medicine, CIBERSAM, Universidad Complutense, Madrid (Alloza, Arango, Janssen, Martinez); NORMENT, K.G. Jebsen Center for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo (Agartz); Department of Psychiatry, Ullevål University Hospital and Institute of Psychiatry, University of Oslo, Oslo (Andreassen); Laboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Rome (Banaj, Piras, Spalletta); Mind Research Network and Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque (Calhoun); Neuroscience Research Australia and School of Psychiatry, University of New South Wales, Sydney (Carr); Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin (Corvin); Olin Neuropsychiatric Research Center, Institute of Living, Hartford Hospital and Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Glahn); Department of Psychiatry, University of Pennsylvania, Philadelphia (Gur, Roalf, Satterthwaite); Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore (Hong, Kochunov, Rowland); National Institute of Mental Health, Klecany, Czech Republic (Hoschl, Spaniel); Department of Psychiatry and Mental Health (Howells, Stein, Uhlmann) and Neuroscience Institute (Howells, Stein), University of Cape Town, Cape Town, South Africa; Highfield Unit, Warneford Hospital, Oxford, U.K. (James); Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, N.Mex. (Liu); Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Carlton South, Australia (Pantelis, Zalesky); Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine (Potkin); Priority Centre for Brain and Mental Health Research (Schall, Rasser) and Priority Research Centre for Stroke and Brain Injury, University of Newcastle, Newcastle, Australia (Rasser); Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston (Spalletta); Kimel Family Translational Imaging-Genetics Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto (Voineskos); Department of Biomedical Engineering and Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia (Zalesky); Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, and Center for the Neurobiology of Learning and Memory, University of California Irvine, Irvine (van Erp); Department of Psychology, Georgia State University, Atlanta (Turner); and Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh (Deary).

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http://dx.doi.org/10.1176/appi.ajp.2019.19030225DOI Listing
June 2020

The genetic architecture of the human cerebral cortex.

Authors:
Katrina L Grasby Neda Jahanshad Jodie N Painter Lucía Colodro-Conde Janita Bralten Derrek P Hibar Penelope A Lind Fabrizio Pizzagalli Christopher R K Ching Mary Agnes B McMahon Natalia Shatokhina Leo C P Zsembik Sophia I Thomopoulos Alyssa H Zhu Lachlan T Strike Ingrid Agartz Saud Alhusaini Marcio A A Almeida Dag Alnæs Inge K Amlien Micael Andersson Tyler Ard Nicola J Armstrong Allison Ashley-Koch Joshua R Atkins Manon Bernard Rachel M Brouwer Elizabeth E L Buimer Robin Bülow Christian Bürger Dara M Cannon Mallar Chakravarty Qiang Chen Joshua W Cheung Baptiste Couvy-Duchesne Anders M Dale Shareefa Dalvie Tânia K de Araujo Greig I de Zubicaray Sonja M C de Zwarte Anouk den Braber Nhat Trung Doan Katharina Dohm Stefan Ehrlich Hannah-Ruth Engelbrecht Susanne Erk Chun Chieh Fan Iryna O Fedko Sonya F Foley Judith M Ford Masaki Fukunaga Melanie E Garrett Tian Ge Sudheer Giddaluru Aaron L Goldman Melissa J Green Nynke A Groenewold Dominik Grotegerd Tiril P Gurholt Boris A Gutman Narelle K Hansell Mathew A Harris Marc B Harrison Courtney C Haswell Michael Hauser Stefan Herms Dirk J Heslenfeld New Fei Ho David Hoehn Per Hoffmann Laurena Holleran Martine Hoogman Jouke-Jan Hottenga Masashi Ikeda Deborah Janowitz Iris E Jansen Tianye Jia Christiane Jockwitz Ryota Kanai Sherif Karama Dalia Kasperaviciute Tobias Kaufmann Sinead Kelly Masataka Kikuchi Marieke Klein Michael Knapp Annchen R Knodt Bernd Krämer Max Lam Thomas M Lancaster Phil H Lee Tristram A Lett Lindsay B Lewis Iscia Lopes-Cendes Michelle Luciano Fabio Macciardi Andre F Marquand Samuel R Mathias Tracy R Melzer Yuri Milaneschi Nazanin Mirza-Schreiber Jose C V Moreira Thomas W Mühleisen Bertram Müller-Myhsok Pablo Najt Soichiro Nakahara Kwangsik Nho Loes M Olde Loohuis Dimitri Papadopoulos Orfanos John F Pearson Toni L Pitcher Benno Pütz Yann Quidé Anjanibhargavi Ragothaman Faisal M Rashid William R Reay Ronny Redlich Céline S Reinbold Jonathan Repple Geneviève Richard Brandalyn C Riedel Shannon L Risacher Cristiane S Rocha Nina Roth Mota Lauren Salminen Arvin Saremi Andrew J Saykin Fenja Schlag Lianne Schmaal Peter R Schofield Rodrigo Secolin Chin Yang Shapland Li Shen Jean Shin Elena Shumskaya Ida E Sønderby Emma Sprooten Katherine E Tansey Alexander Teumer Anbupalam Thalamuthu Diana Tordesillas-Gutiérrez Jessica A Turner Anne Uhlmann Costanza Ludovica Vallerga Dennis van der Meer Marjolein M J van Donkelaar Liza van Eijk Theo G M van Erp Neeltje E M van Haren Daan van Rooij Marie-José van Tol Jan H Veldink Ellen Verhoef Esther Walton Mingyuan Wang Yunpeng Wang Joanna M Wardlaw Wei Wen Lars T Westlye Christopher D Whelan Stephanie H Witt Katharina Wittfeld Christiane Wolf Thomas Wolfers Jing Qin Wu Clarissa L Yasuda Dario Zaremba Zuo Zhang Marcel P Zwiers Eric Artiges Amelia A Assareh Rosa Ayesa-Arriola Aysenil Belger Christine L Brandt Gregory G Brown Sven Cichon Joanne E Curran Gareth E Davies Franziska Degenhardt Michelle F Dennis Bruno Dietsche Srdjan Djurovic Colin P Doherty Ryan Espiritu Daniel Garijo Yolanda Gil Penny A Gowland Robert C Green Alexander N Häusler Walter Heindel Beng-Choon Ho Wolfgang U Hoffmann Florian Holsboer Georg Homuth Norbert Hosten Clifford R Jack MiHyun Jang Andreas Jansen Nathan A Kimbrel Knut Kolskår Sanne Koops Axel Krug Kelvin O Lim Jurjen J Luykx Daniel H Mathalon Karen A Mather Venkata S Mattay Sarah Matthews Jaqueline Mayoral Van Son Sarah C McEwen Ingrid Melle Derek W Morris Bryon A Mueller Matthias Nauck Jan E Nordvik Markus M Nöthen Daniel S O'Leary Nils Opel Marie-Laure Paillère Martinot G Bruce Pike Adrian Preda Erin B Quinlan Paul E Rasser Varun Ratnakar Simone Reppermund Vidar M Steen Paul A Tooney Fábio R Torres Dick J Veltman James T Voyvodic Robert Whelan Tonya White Hidenaga Yamamori Hieab H H Adams Joshua C Bis Stephanie Debette Charles Decarli Myriam Fornage Vilmundur Gudnason Edith Hofer M Arfan Ikram Lenore Launer W T Longstreth Oscar L Lopez Bernard Mazoyer Thomas H Mosley Gennady V Roshchupkin Claudia L Satizabal Reinhold Schmidt Sudha Seshadri Qiong Yang Marina K M Alvim David Ames Tim J Anderson Ole A Andreassen Alejandro Arias-Vasquez Mark E Bastin Bernhard T Baune Jean C Beckham John Blangero Dorret I Boomsma Henry Brodaty Han G Brunner Randy L Buckner Jan K Buitelaar Juan R Bustillo Wiepke Cahn Murray J Cairns Vince Calhoun Vaughan J Carr Xavier Caseras Svenja Caspers Gianpiero L Cavalleri Fernando Cendes Aiden Corvin Benedicto Crespo-Facorro John C Dalrymple-Alford Udo Dannlowski Eco J C de Geus Ian J Deary Norman Delanty Chantal Depondt Sylvane Desrivières Gary Donohoe Thomas Espeseth Guillén Fernández Simon E Fisher Herta Flor Andreas J Forstner Clyde Francks Barbara Franke David C Glahn Randy L Gollub Hans J Grabe Oliver Gruber Asta K Håberg Ahmad R Hariri Catharina A Hartman Ryota Hashimoto Andreas Heinz Frans A Henskens Manon H J Hillegers Pieter J Hoekstra Avram J Holmes L Elliot Hong William D Hopkins Hilleke E Hulshoff Pol Terry L Jernigan Erik G Jönsson René S Kahn Martin A Kennedy Tilo T J Kircher Peter Kochunov John B J Kwok Stephanie Le Hellard Carmel M Loughland Nicholas G Martin Jean-Luc Martinot Colm McDonald Katie L McMahon Andreas Meyer-Lindenberg Patricia T Michie Rajendra A Morey Bryan Mowry Lars Nyberg Jaap Oosterlaan Roel A Ophoff Christos Pantelis Tomas Paus Zdenka Pausova Brenda W J H Penninx Tinca J C Polderman Danielle Posthuma Marcella Rietschel Joshua L Roffman Laura M Rowland Perminder S Sachdev Philipp G Sämann Ulrich Schall Gunter Schumann Rodney J Scott Kang Sim Sanjay M Sisodiya Jordan W Smoller Iris E Sommer Beate St Pourcain Dan J Stein Arthur W Toga Julian N Trollor Nic J A Van der Wee Dennis van 't Ent Henry Völzke Henrik Walter Bernd Weber Daniel R Weinberger Margaret J Wright Juan Zhou Jason L Stein Paul M Thompson Sarah E Medland

Science 2020 03;367(6484)

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http://dx.doi.org/10.1126/science.aay6690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295264PMC
March 2020

Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers.

J Gerontol A Biol Sci Med Sci 2020 Mar 10. Epub 2020 Mar 10.

Epidemiology and Biostatistics, Department of Public Health, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1093/gerona/glaa066DOI Listing
March 2020

Generational differences in loneliness and its psychological and sociodemographic predictors: an exploratory and confirmatory machine learning study.

Psychol Med 2020 Mar 9:1-10. Epub 2020 Mar 9.

Department of Psychology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1017/S0033291719003933DOI Listing
March 2020

DNA methylation-based measures of accelerated biological ageing and the risk of dementia in the oldest-old: a study of the Lothian Birth Cohort 1921.

BMC Psychiatry 2020 02 28;20(1):91. Epub 2020 Feb 28.

Alzheimer Scotland Dementia Research Centre, University of Edinburgh, 7 George Square, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1186/s12888-020-2469-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048023PMC
February 2020

Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis.

BMJ 2020 02 12;368:m131. Epub 2020 Feb 12.

British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1136/bmj.m131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190071PMC
February 2020

Education, intelligence and Alzheimer's disease: evidence from a multivariable two-sample Mendelian randomization study.

Int J Epidemiol 2020 Jan 31. Epub 2020 Jan 31.

Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/ije/dyz280DOI Listing
January 2020

Attitudes to ageing, biomarkers of ageing and mortality: the Lothian Birth Cohort 1936.

J Epidemiol Community Health 2020 04 28;74(4):377-383. Epub 2020 Jan 28.

Psychology, The University of Edinburgh, Edinburgh, UK

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http://dx.doi.org/10.1136/jech-2019-213462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079194PMC
April 2020

Associations Between Declining Physical and Cognitive Functions in the Lothian Birth Cohort 1936.

J Gerontol A Biol Sci Med Sci 2020 Jun;75(7):1393-1402

Lothian Birth Cohort Studies, Department of Psychology, University of Edinburgh, UK.

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http://dx.doi.org/10.1093/gerona/glaa023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447860PMC
June 2020

The effect of network thresholding and weighting on structural brain networks in the UK Biobank.

Neuroimage 2020 05 10;211:116443. Epub 2020 Jan 10.

Lothian Birth Cohorts group, The University of Edinburgh, Edinburgh, UK; Department of Psychology, The University of Edinburgh, Edinburgh, UK; Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2019.116443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085460PMC
May 2020

Computational quantification of brain perivascular space morphologies: Associations with vascular risk factors and white matter hyperintensities. A study in the Lothian Birth Cohort 1936.

Neuroimage Clin 2020 9;25:102120. Epub 2019 Dec 9.

Division of Neuroimaging Sciences, Centre for Clinical Brain Sciences and Edinburgh Imaging, University of Edinburgh, Edinburgh, UK; UK Dementia Research Institute at the University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.102120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939098PMC
December 2019

Navigating the landscape of non-health administrative data in Scotland: A researcher's narrative.

Wellcome Open Res 2019 21;4:97. Epub 2019 Oct 21.

Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.12688/wellcomeopenres.15336.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886011PMC
October 2019

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group.

Mol Psychiatry 2019 Dec 6. Epub 2019 Dec 6.

Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1038/s41380-019-0605-zDOI Listing
December 2019

Loss-of-Function Mutations in the ALPL Gene Presenting with Adult Onset Osteoporosis and Low Serum Concentrations of Total Alkaline Phosphatase.

J Bone Miner Res 2020 Apr 7;35(4):657-661. Epub 2020 Jan 7.

Rheumatology and Bone Disease Unit, Centre for Genomic and Experimental Medicine, MRC institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1002/jbmr.3928DOI Listing
April 2020

Childhood intelligence attenuates the association between biological ageing and health outcomes in later life.

Transl Psychiatry 2019 11 28;9(1):323. Epub 2019 Nov 28.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41398-019-0657-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883059PMC
November 2019

Playing Analog Games Is Associated With Reduced Declines in Cognitive Function: A 68-Year Longitudinal Cohort Study.

J Gerontol B Psychol Sci Soc Sci 2020 Feb;75(3):474-482

Department of Psychology, The University of Edinburgh, UK.

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http://dx.doi.org/10.1093/geronb/gbz149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021446PMC
February 2020

Playing Analog Games Is Associated With Reduced Declines in Cognitive Function: A 68-Year Longitudinal Cohort Study.

J Gerontol B Psychol Sci Soc Sci 2020 Feb;75(3):474-482

Department of Psychology, The University of Edinburgh, UK.

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http://dx.doi.org/10.1093/geronb/gbz149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021446PMC
February 2020

Cross-sectional associations between personality traits and device-based measures of step count and sedentary behaviour in older age: the Lothian Birth Cohort 1936.

BMC Geriatr 2019 11 10;19(1):302. Epub 2019 Nov 10.

Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1186/s12877-019-1328-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842536PMC
November 2019

Sleep and brain morphological changes in the eighth decade of life.

Sleep Med 2020 01 24;65:152-158. Epub 2019 Jul 24.

Brain Research Imaging Centre, Division of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK; Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE), UK; UK Dementia Research Institute, University of Edinburgh, UK. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2019.07.015DOI Listing
January 2020

Physical frailty and decline in general and specific cognitive abilities: the Lothian Birth Cohort 1936.

J Epidemiol Community Health 2020 02 5;74(2):108-113. Epub 2019 Nov 5.

Psychology, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1136/jech-2019-213280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993023PMC
February 2020

Associations between Brief Resilience Scale scores and ageing-related domains in the Lothian Birth Cohort 1936.

Psychol Aging 2020 May 4;35(3):329-344. Epub 2019 Nov 4.

Centre for Cognitive Ageing and Cognitive Epidemiology.

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http://dx.doi.org/10.1037/pag0000419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161361PMC
May 2020

Associations of autozygosity with a broad range of human phenotypes.

Authors:
David W Clark Yukinori Okada Kristjan H S Moore Dan Mason Nicola Pirastu Ilaria Gandin Hannele Mattsson Catriona L K Barnes Kuang Lin Jing Hua Zhao Patrick Deelen Rebecca Rohde Claudia Schurmann Xiuqing Guo Franco Giulianini Weihua Zhang Carolina Medina-Gomez Robert Karlsson Yanchun Bao Traci M Bartz Clemens Baumbach Ginevra Biino Matthew J Bixley Marco Brumat Jin-Fang Chai Tanguy Corre Diana L Cousminer Annelot M Dekker David A Eccles Kristel R van Eijk Christian Fuchsberger He Gao Marine Germain Scott D Gordon Hugoline G de Haan Sarah E Harris Edith Hofer Alicia Huerta-Chagoya Catherine Igartua Iris E Jansen Yucheng Jia Tim Kacprowski Torgny Karlsson Marcus E Kleber Shengchao Alfred Li Ruifang Li-Gao Anubha Mahajan Koichi Matsuda Karina Meidtner Weihua Meng May E Montasser Peter J van der Most Matthias Munz Teresa Nutile Teemu Palviainen Gauri Prasad Rashmi B Prasad Tallapragada Divya Sri Priyanka Federica Rizzi Erika Salvi Bishwa R Sapkota Daniel Shriner Line Skotte Melissa C Smart Albert Vernon Smith Ashley van der Spek Cassandra N Spracklen Rona J Strawbridge Salman M Tajuddin Stella Trompet Constance Turman Niek Verweij Clara Viberti Lihua Wang Helen R Warren Robyn E Wootton Lisa R Yanek Jie Yao Noha A Yousri Wei Zhao Adebowale A Adeyemo Saima Afaq Carlos Alberto Aguilar-Salinas Masato Akiyama Matthew L Albert Matthew A Allison Maris Alver Tin Aung Fereidoun Azizi Amy R Bentley Heiner Boeing Eric Boerwinkle Judith B Borja Gert J de Borst Erwin P Bottinger Linda Broer Harry Campbell Stephen Chanock Miao-Li Chee Guanjie Chen Yii-Der I Chen Zhengming Chen Yen-Feng Chiu Massimiliano Cocca Francis S Collins Maria Pina Concas Janie Corley Giovanni Cugliari Rob M van Dam Anna Damulina Maryam S Daneshpour Felix R Day Graciela E Delgado Klodian Dhana Alexander S F Doney Marcus Dörr Ayo P Doumatey Nduna Dzimiri S Sunna Ebenesersdóttir Joshua Elliott Paul Elliott Ralf Ewert Janine F Felix Krista Fischer Barry I Freedman Giorgia Girotto Anuj Goel Martin Gögele Mark O Goodarzi Mariaelisa Graff Einat Granot-Hershkovitz Francine Grodstein Simonetta Guarrera Daniel F Gudbjartsson Kamran Guity Bjarni Gunnarsson Yu Guo Saskia P Hagenaars Christopher A Haiman Avner Halevy Tamara B Harris Mehdi Hedayati David A van Heel Makoto Hirata Imo Höfer Chao Agnes Hsiung Jinyan Huang Yi-Jen Hung M Arfan Ikram Anuradha Jagadeesan Pekka Jousilahti Yoichiro Kamatani Masahiro Kanai Nicola D Kerrison Thorsten Kessler Kay-Tee Khaw Chiea Chuen Khor Dominique P V de Kleijn Woon-Puay Koh Ivana Kolcic Peter Kraft Bernhard K Krämer Zoltán Kutalik Johanna Kuusisto Claudia Langenberg Lenore J Launer Deborah A Lawlor I-Te Lee Wen-Jane Lee Markus M Lerch Liming Li Jianjun Liu Marie Loh Stephanie J London Stephanie Loomis Yingchang Lu Jian'an Luan Reedik Mägi Ani W Manichaikul Paolo Manunta Gísli Másson Nana Matoba Xue W Mei Christa Meisinger Thomas Meitinger Massimo Mezzavilla Lili Milani Iona Y Millwood Yukihide Momozawa Amy Moore Pierre-Emmanuel Morange Hortensia Moreno-Macías Trevor A Mori Alanna C Morrison Taulant Muka Yoshinori Murakami Alison D Murray Renée de Mutsert Josyf C Mychaleckyj Mike A Nalls Matthias Nauck Matt J Neville Ilja M Nolte Ken K Ong Lorena Orozco Sandosh Padmanabhan Gunnar Pálsson James S Pankow Cristian Pattaro Alison Pattie Ozren Polasek Neil Poulter Peter P Pramstaller Lluis Quintana-Murci Katri Räikkönen Sarju Ralhan Dabeeru C Rao Wouter van Rheenen Stephen S Rich Paul M Ridker Cornelius A Rietveld Antonietta Robino Frank J A van Rooij Daniela Ruggiero Yasaman Saba Charumathi Sabanayagam Maria Sabater-Lleal Cinzia Felicita Sala Veikko Salomaa Kevin Sandow Helena Schmidt Laura J Scott William R Scott Bahareh Sedaghati-Khayat Bengt Sennblad Jessica van Setten Peter J Sever Wayne H-H Sheu Yuan Shi Smeeta Shrestha Sharvari Rahul Shukla Jon K Sigurdsson Timo Tonis Sikka Jai Rup Singh Blair H Smith Alena Stančáková Alice Stanton John M Starr Lilja Stefansdottir Leon Straker Patrick Sulem Gardar Sveinbjornsson Morris A Swertz Adele M Taylor Kent D Taylor Natalie Terzikhan Yih-Chung Tham Gudmar Thorleifsson Unnur Thorsteinsdottir Annika Tillander Russell P Tracy Teresa Tusié-Luna Ioanna Tzoulaki Simona Vaccargiu Jagadish Vangipurapu Jan H Veldink Veronique Vitart Uwe Völker Eero Vuoksimaa Salma M Wakil Melanie Waldenberger Gurpreet S Wander Ya Xing Wang Nicholas J Wareham Sarah Wild Chittaranjan S Yajnik Jian-Min Yuan Lingyao Zeng Liang Zhang Jie Zhou Najaf Amin Folkert W Asselbergs Stephan J L Bakker Diane M Becker Benjamin Lehne David A Bennett Leonard H van den Berg Sonja I Berndt Dwaipayan Bharadwaj Lawrence F Bielak Murielle Bochud Mike Boehnke Claude Bouchard Jonathan P Bradfield Jennifer A Brody Archie Campbell Shai Carmi Mark J Caulfield David Cesarini John C Chambers Giriraj Ratan Chandak Ching-Yu Cheng Marina Ciullo Marilyn Cornelis Daniele Cusi George Davey Smith Ian J Deary Rajkumar Dorajoo Cornelia M van Duijn David Ellinghaus Jeanette Erdmann Johan G Eriksson Evangelos Evangelou Michele K Evans Jessica D Faul Bjarke Feenstra Mary Feitosa Sylvain Foisy Andre Franke Yechiel Friedlander Paolo Gasparini Christian Gieger Clicerio Gonzalez Philippe Goyette Struan F A Grant Lyn R Griffiths Leif Groop Vilmundur Gudnason Ulf Gyllensten Hakon Hakonarson Anders Hamsten Pim van der Harst Chew-Kiat Heng Andrew A Hicks Hagit Hochner Heikki Huikuri Steven C Hunt Vincent W V Jaddoe Philip L De Jager Magnus Johannesson Åsa Johansson Jost B Jonas J Wouter Jukema Juhani Junttila Jaakko Kaprio Sharon L R Kardia Fredrik Karpe Meena Kumari Markku Laakso Sander W van der Laan Jari Lahti Matthias Laudes Rodney A Lea Wolfgang Lieb Thomas Lumley Nicholas G Martin Winfried März Giuseppe Matullo Mark I McCarthy Sarah E Medland Tony R Merriman Andres Metspalu Brian F Meyer Karen L Mohlke Grant W Montgomery Dennis Mook-Kanamori Patricia B Munroe Kari E North Dale R Nyholt Jeffery R O'connell Carole Ober Albertine J Oldehinkel Walter Palmas Colin Palmer Gerard G Pasterkamp Etienne Patin Craig E Pennell Louis Perusse Patricia A Peyser Mario Pirastu Tinca J C Polderman David J Porteous Danielle Posthuma Bruce M Psaty John D Rioux Fernando Rivadeneira Charles Rotimi Jerome I Rotter Igor Rudan Hester M Den Ruijter Dharambir K Sanghera Naveed Sattar Reinhold Schmidt Matthias B Schulze Heribert Schunkert Robert A Scott Alan R Shuldiner Xueling Sim Neil Small Jennifer A Smith Nona Sotoodehnia E-Shyong Tai Alexander Teumer Nicholas J Timpson Daniela Toniolo David-Alexandre Tregouet Tiinamaija Tuomi Peter Vollenweider Carol A Wang David R Weir John B Whitfield Cisca Wijmenga Tien-Yin Wong John Wright Jingyun Yang Lei Yu Babette S Zemel Alan B Zonderman Markus Perola Patrik K E Magnusson André G Uitterlinden Jaspal S Kooner Daniel I Chasman Ruth J F Loos Nora Franceschini Lude Franke Chris S Haley Caroline Hayward Robin G Walters John R B Perry Tōnu Esko Agnar Helgason Kari Stefansson Peter K Joshi Michiaki Kubo James F Wilson

Nat Commun 2019 10 31;10(1):4957. Epub 2019 Oct 31.

Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, Scotland.

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http://dx.doi.org/10.1038/s41467-019-12283-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823371PMC
October 2019

Genetic correlations between pain phenotypes and depression and neuroticism.

Eur J Hum Genet 2020 03 29;28(3):358-366. Epub 2019 Oct 29.

Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, DD2 4BF, UK.

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http://dx.doi.org/10.1038/s41431-019-0530-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028719PMC
March 2020

Genetic architecture of subcortical brain structures in 38,851 individuals.

Authors:
Claudia L Satizabal Hieab H H Adams Derrek P Hibar Charles C White Maria J Knol Jason L Stein Markus Scholz Muralidharan Sargurupremraj Neda Jahanshad Gennady V Roshchupkin Albert V Smith Joshua C Bis Xueqiu Jian Michelle Luciano Edith Hofer Alexander Teumer Sven J van der Lee Jingyun Yang Lisa R Yanek Tom V Lee Shuo Li Yanhui Hu Jia Yu Koh John D Eicher Sylvane Desrivières Alejandro Arias-Vasquez Ganesh Chauhan Lavinia Athanasiu Miguel E Rentería Sungeun Kim David Hoehn Nicola J Armstrong Qiang Chen Avram J Holmes Anouk den Braber Iwona Kloszewska Micael Andersson Thomas Espeseth Oliver Grimm Lucija Abramovic Saud Alhusaini Yuri Milaneschi Martina Papmeyer Tomas Axelsson Stefan Ehrlich Roberto Roiz-Santiañez Bernd Kraemer Asta K Håberg Hannah J Jones G Bruce Pike Dan J Stein Allison Stevens Janita Bralten Meike W Vernooij Tamara B Harris Irina Filippi A Veronica Witte Tulio Guadalupe Katharina Wittfeld Thomas H Mosley James T Becker Nhat Trung Doan Saskia P Hagenaars Yasaman Saba Gabriel Cuellar-Partida Najaf Amin Saima Hilal Kwangsik Nho Nazanin Mirza-Schreiber Konstantinos Arfanakis Diane M Becker David Ames Aaron L Goldman Phil H Lee Dorret I Boomsma Simon Lovestone Sudheer Giddaluru Stephanie Le Hellard Manuel Mattheisen Marc M Bohlken Dalia Kasperaviciute Lianne Schmaal Stephen M Lawrie Ingrid Agartz Esther Walton Diana Tordesillas-Gutierrez Gareth E Davies Jean Shin Jonathan C Ipser Louis N Vinke Martine Hoogman Tianye Jia Ralph Burkhardt Marieke Klein Fabrice Crivello Deborah Janowitz Owen Carmichael Unn K Haukvik Benjamin S Aribisala Helena Schmidt Lachlan T Strike Ching-Yu Cheng Shannon L Risacher Benno Pütz Debra A Fleischman Amelia A Assareh Venkata S Mattay Randy L Buckner Patrizia Mecocci Anders M Dale Sven Cichon Marco P Boks Mar Matarin Brenda W J H Penninx Vince D Calhoun M Mallar Chakravarty Andre F Marquand Christine Macare Shahrzad Kharabian Masouleh Jaap Oosterlaan Philippe Amouyel Katrin Hegenscheid Jerome I Rotter Andrew J Schork David C M Liewald Greig I de Zubicaray Tien Yin Wong Li Shen Philipp G Sämann Henry Brodaty Joshua L Roffman Eco J C de Geus Magda Tsolaki Susanne Erk Kristel R van Eijk Gianpiero L Cavalleri Nic J A van der Wee Andrew M McIntosh Randy L Gollub Kazima B Bulayeva Manon Bernard Jennifer S Richards Jayandra J Himali Markus Loeffler Nanda Rommelse Wolfgang Hoffmann Lars T Westlye Maria C Valdés Hernández Narelle K Hansell Theo G M van Erp Christiane Wolf John B J Kwok Bruno Vellas Andreas Heinz Loes M Olde Loohuis Norman Delanty Beng-Choon Ho Christopher R K Ching Elena Shumskaya Baljeet Singh Albert Hofman Dennis van der Meer Georg Homuth Bruce M Psaty Mark E Bastin Grant W Montgomery Tatiana M Foroud Simone Reppermund Jouke-Jan Hottenga Andrew Simmons Andreas Meyer-Lindenberg Wiepke Cahn Christopher D Whelan Marjolein M J van Donkelaar Qiong Yang Norbert Hosten Robert C Green Anbupalam Thalamuthu Sebastian Mohnke Hilleke E Hulshoff Pol Honghuang Lin Clifford R Jack Peter R Schofield Thomas W Mühleisen Pauline Maillard Steven G Potkin Wei Wen Evan Fletcher Arthur W Toga Oliver Gruber Matthew Huentelman George Davey Smith Lenore J Launer Lars Nyberg Erik G Jönsson Benedicto Crespo-Facorro Nastassja Koen Douglas N Greve André G Uitterlinden Daniel R Weinberger Vidar M Steen Iryna O Fedko Nynke A Groenewold Wiro J Niessen Roberto Toro Christophe Tzourio William T Longstreth M Kamran Ikram Jordan W Smoller Marie-Jose van Tol Jessika E Sussmann Tomas Paus Hervé Lemaître Matthias L Schroeter Bernard Mazoyer Ole A Andreassen Florian Holsboer Chantal Depondt Dick J Veltman Jessica A Turner Zdenka Pausova Gunter Schumann Daan van Rooij Srdjan Djurovic Ian J Deary Katie L McMahon Bertram Müller-Myhsok Rachel M Brouwer Hilkka Soininen Massimo Pandolfo Thomas H Wassink Joshua W Cheung Thomas Wolfers Jean-Luc Martinot Marcel P Zwiers Matthias Nauck Ingrid Melle Nicholas G Martin Ryota Kanai Eric Westman René S Kahn Sanjay M Sisodiya Tonya White Arvin Saremi Hans van Bokhoven Han G Brunner Henry Völzke Margaret J Wright Dennis van 't Ent Markus M Nöthen Roel A Ophoff Jan K Buitelaar Guillén Fernández Perminder S Sachdev Marcella Rietschel Neeltje E M van Haren Simon E Fisher Alexa S Beiser Clyde Francks Andrew J Saykin Karen A Mather Nina Romanczuk-Seiferth Catharina A Hartman Anita L DeStefano Dirk J Heslenfeld Michael W Weiner Henrik Walter Pieter J Hoekstra Paul A Nyquist Barbara Franke David A Bennett Hans J Grabe Andrew D Johnson Christopher Chen Cornelia M van Duijn Oscar L Lopez Myriam Fornage Joanna M Wardlaw Reinhold Schmidt Charles DeCarli Philip L De Jager Arno Villringer Stéphanie Debette Vilmundur Gudnason Sarah E Medland Joshua M Shulman Paul M Thompson Sudha Seshadri M Arfan Ikram

Nat Genet 2019 11 21;51(11):1624-1636. Epub 2019 Oct 21.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1038/s41588-019-0511-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055269PMC
November 2019

Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study.

J Gerontol A Biol Sci Med Sci 2020 Feb;75(3):473-480

Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, UK.

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http://dx.doi.org/10.1093/gerona/glz245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328191PMC
February 2020

Predicting incident dementia 3-8 years after brief cognitive tests in the UK Biobank prospective study of 500,000 people.

Alzheimers Dement 2019 12 13;15(12):1546-1557. Epub 2019 Oct 13.

Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE), Department of Psychology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.jalz.2019.07.014DOI Listing
December 2019

Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition.

Psychol Med 2019 Oct 2:1-10. Epub 2019 Oct 2.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1017/S0033291719002629DOI Listing
October 2019

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.

Epigenomics 2019 10 19;11(13):1487-1500. Epub 2019 Sep 19.

Department of Health & Human Services, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.2217/epi-2019-0066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836223PMC
October 2019

Multivariable two-sample Mendelian randomization estimates of the effects of intelligence and education on health.

Elife 2019 09 17;8. Epub 2019 Sep 17.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.7554/eLife.43990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748790PMC
September 2019

Predisposing Risk Factors for Functional Limb Weakness: A Case-Control Study.

J Neuropsychiatry Clin Neurosci 2020 30;32(1):50-57. Epub 2019 Aug 30.

The Centre for Clinical Brain Sciences, University of Edinburgh, Royal Infirmary, Edinburgh, United Kingdom (Stone, Warlow); the Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, United Kingdom (Deary); the Department of Psychological Medicine Research, University of Oxford, United Kingdom (Sharpe).

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http://dx.doi.org/10.1176/appi.neuropsych.19050109DOI Listing
October 2020

Early-life predictors of retirement decisions and post-retirement health.

SSM Popul Health 2019 Aug 10;8:100430. Epub 2019 Jun 10.

The Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.ssmph.2019.100430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580092PMC
August 2019

Age-related clonal haemopoiesis is associated with increased epigenetic age.

Curr Biol 2019 08;29(16):R786-R787

MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2019.07.011DOI Listing
August 2019

Understanding cognitive impairment in mood disorders: mediation analyses in the UK Biobank cohort.

Br J Psychiatry 2019 Aug 15:1-8. Epub 2019 Aug 15.

Professor, Institute of Health and Wellbeing, University of Glasgow, UK.

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http://dx.doi.org/10.1192/bjp.2019.188DOI Listing
August 2019

Brain Peak Width of Skeletonized Mean Diffusivity (PSMD) and Cognitive Function in Later Life.

Front Psychiatry 2019 26;10:524. Epub 2019 Jul 26.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.3389/fpsyt.2019.00524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676305PMC
July 2019

Longitudinal associations between hearing loss and general cognitive ability: The Lothian Birth Cohort 1936.

Psychol Aging 2019 Sep 8;34(6):766-779. Epub 2019 Aug 8.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh.

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http://dx.doi.org/10.1037/pag0000385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742482PMC
September 2019

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

Am J Hum Genet 2019 08;105(2):334-350

Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699140PMC
August 2019

Genetic Contributions to Health Literacy.

Twin Res Hum Genet 2019 06;22(3):131-139

Centre for Cognitive Ageing and Cognitive Epidemiology,University of Edinburgh,Edinburgh, UK.

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http://dx.doi.org/10.1017/thg.2019.28DOI Listing
June 2019

Perivascular spaces in the centrum semiovale at the beginning of the 8th decade of life: effect on cognition and associations with mineral deposition.

Brain Imaging Behav 2020 Oct;14(5):1865-1875

Department of Neuroimaging Sciences, Centre for Clinical Brain Sciences, University of Edinburgh, 49 Little France Crescent, Chancellor's Building, Edinburgh, EH16 4SB, UK.

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http://dx.doi.org/10.1007/s11682-019-00128-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572330PMC
October 2020

Impact of Polygenic Risk for Schizophrenia on Cortical Structure in UK Biobank.

Biol Psychiatry 2019 10 22;86(7):536-544. Epub 2019 Apr 22.

Division of Psychiatry, Royal Edinburgh Hospital, Edinburgh, UK; The Patrick Wild Centre, Royal Edinburgh Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.biopsych.2019.04.013DOI Listing
October 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Authors:
Valérie Turcot Yingchang Lu Heather M Highland Claudia Schurmann Anne E Justice Rebecca S Fine Jonathan P Bradfield Tõnu Esko Ayush Giri Mariaelisa Graff Xiuqing Guo Audrey E Hendricks Tugce Karaderi Adelheid Lempradl Adam E Locke Anubha Mahajan Eirini Marouli Suthesh Sivapalaratnam Kristin L Young Tamuno Alfred Mary F Feitosa Nicholas G D Masca Alisa K Manning Carolina Medina-Gomez Poorva Mudgal Maggie C Y Ng Alex P Reiner Sailaja Vedantam Sara M Willems Thomas W Winkler Gonçalo Abecasis Katja K Aben Dewan S Alam Sameer E Alharthi Matthew Allison Philippe Amouyel Folkert W Asselbergs Paul L Auer Beverley Balkau Lia E Bang Inês Barroso Lisa Bastarache Marianne Benn Sven Bergmann Lawrence F Bielak Matthias Blüher Michael Boehnke Heiner Boeing Eric Boerwinkle Carsten A Böger Jette Bork-Jensen Michiel L Bots Erwin P Bottinger Donald W Bowden Ivan Brandslund Gerome Breen Murray H Brilliant Linda Broer Marco Brumat Amber A Burt Adam S Butterworth Peter T Campbell Stefania Cappellani David J Carey Eulalia Catamo Mark J Caulfield John C Chambers Daniel I Chasman Yii-Der I Chen Rajiv Chowdhury Cramer Christensen Audrey Y Chu Massimiliano Cocca Francis S Collins James P Cook Janie Corley Jordi Corominas Galbany Amanda J Cox David S Crosslin Gabriel Cuellar-Partida Angela D'Eustacchio John Danesh Gail Davies Paul I W Bakker Mark C H Groot Renée Mutsert Ian J Deary George Dedoussis Ellen W Demerath Martin Heijer Anneke I Hollander Hester M Ruijter Joe G Dennis Josh C Denny Emanuele Di Angelantonio Fotios Drenos Mengmeng Du Marie-Pierre Dubé Alison M Dunning Douglas F Easton Todd L Edwards David Ellinghaus Patrick T Ellinor Paul Elliott Evangelos Evangelou Aliki-Eleni Farmaki I Sadaf Farooqi Jessica D Faul Sascha Fauser Shuang Feng Ele Ferrannini Jean Ferrieres Jose C Florez Ian Ford Myriam Fornage Oscar H Franco Andre Franke Paul W Franks Nele Friedrich Ruth Frikke-Schmidt Tessel E Galesloot Wei Gan Ilaria Gandin Paolo Gasparini Jane Gibson Vilmantas Giedraitis Anette P Gjesing Penny Gordon-Larsen Mathias Gorski Hans-Jörgen Grabe Struan F A Grant Niels Grarup Helen L Griffiths Megan L Grove Vilmundur Gudnason Stefan Gustafsson Jeff Haessler Hakon Hakonarson Anke R Hammerschlag Torben Hansen Kathleen Mullan Harris Tamara B Harris Andrew T Hattersley Christian T Have Caroline Hayward Liang He Nancy L Heard-Costa Andrew C Heath Iris M Heid Øyvind Helgeland Jussi Hernesniemi Alex W Hewitt Oddgeir L Holmen G Kees Hovingh Joanna M M Howson Yao Hu Paul L Huang Jennifer E Huffman M Arfan Ikram Erik Ingelsson Anne U Jackson Jan-Håkan Jansson Gail P Jarvik Gorm B Jensen Yucheng Jia Stefan Johansson Marit E Jørgensen Torben Jørgensen J Wouter Jukema Bratati Kahali René S Kahn Mika Kähönen Pia R Kamstrup Stavroula Kanoni Jaakko Kaprio Maria Karaleftheri Sharon L R Kardia Fredrik Karpe Sekar Kathiresan Frank Kee Lambertus A Kiemeney Eric Kim Hidetoshi Kitajima Pirjo Komulainen Jaspal S Kooner Charles Kooperberg Tellervo Korhonen Peter Kovacs Helena Kuivaniemi Zoltán Kutalik Kari Kuulasmaa Johanna Kuusisto Markku Laakso Timo A Lakka David Lamparter Ethan M Lange Leslie A Lange Claudia Langenberg Eric B Larson Nanette R Lee Terho Lehtimäki Cora E Lewis Huaixing Li Jin Li Ruifang Li-Gao Honghuang Lin Keng-Hung Lin Li-An Lin Xu Lin Lars Lind Jaana Lindström Allan Linneberg Ching-Ti Liu Dajiang J Liu Yongmei Liu Ken S Lo Artitaya Lophatananon Andrew J Lotery Anu Loukola Jian'an Luan Steven A Lubitz Leo-Pekka Lyytikäinen Satu Männistö Gaëlle Marenne Angela L Mazul Mark I McCarthy Roberta McKean-Cowdin Sarah E Medland Karina Meidtner Lili Milani Vanisha Mistry Paul Mitchell Karen L Mohlke Leena Moilanen Marie Moitry Grant W Montgomery Dennis O Mook-Kanamori Carmel Moore Trevor A Mori Andrew D Morris Andrew P Morris Martina Müller-Nurasyid Patricia B Munroe Mike A Nalls Narisu Narisu Christopher P Nelson Matt Neville Sune F Nielsen Kjell Nikus Pål R Njølstad Børge G Nordestgaard Dale R Nyholt Jeffrey R O'Connel Michelle L O'Donoghue Loes M Olde Loohuis Roel A Ophoff Katharine R Owen Chris J Packard Sandosh Padmanabhan Colin N A Palmer Nicholette D Palmer Gerard Pasterkamp Aniruddh P Patel Alison Pattie Oluf Pedersen Peggy L Peissig Gina M Peloso Craig E Pennell Markus Perola James A Perry John R B Perry Tune H Pers Thomas N Person Annette Peters Eva R B Petersen Patricia A Peyser Ailith Pirie Ozren Polasek Tinca J Polderman Hannu Puolijoki Olli T Raitakari Asif Rasheed Rainer Rauramaa Dermot F Reilly Frida Renström Myriam Rheinberger Paul M Ridker John D Rioux Manuel A Rivas David J Roberts Neil R Robertson Antonietta Robino Olov Rolandsson Igor Rudan Katherine S Ruth Danish Saleheen Veikko Salomaa Nilesh J Samani Yadav Sapkota Naveed Sattar Robert E Schoen Pamela J Schreiner Matthias B Schulze Robert A Scott Marcelo P Segura-Lepe Svati H Shah Wayne H-H Sheu Xueling Sim Andrew J Slater Kerrin S Small Albert V Smith Lorraine Southam Timothy D Spector Elizabeth K Speliotes John M Starr Kari Stefansson Valgerdur Steinthorsdottir Kathleen E Stirrups Konstantin Strauch Heather M Stringham Michael Stumvoll Liang Sun Praveen Surendran Amy J Swift Hayato Tada Katherine E Tansey Jean-Claude Tardif Kent D Taylor Alexander Teumer Deborah J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Betina H Thuesen Anke Tönjes Gerard Tromp Stella Trompet Emmanouil Tsafantakis Jaakko Tuomilehto Anne Tybjaerg-Hansen Jonathan P Tyrer Rudolf Uher André G Uitterlinden Matti Uusitupa Sander W Laan Cornelia M Duijn Nienke Leeuwen Jessica van Setten Mauno Vanhala Anette Varbo Tibor V Varga Rohit Varma Digna R Velez Edwards Sita H Vermeulen Giovanni Veronesi Henrik Vestergaard Veronique Vitart Thomas F Vogt Uwe Völker Dragana Vuckovic Lynne E Wagenknecht Mark Walker Lars Wallentin Feijie Wang Carol A Wang Shuai Wang Yiqin Wang Erin B Ware Nicholas J Wareham Helen R Warren Dawn M Waterworth Jennifer Wessel Harvey D White Cristen J Willer James G Wilson Daniel R Witte Andrew R Wood Ying Wu Hanieh Yaghootkar Jie Yao Pang Yao Laura M Yerges-Armstrong Robin Young Eleftheria Zeggini Xiaowei Zhan Weihua Zhang Jing Hua Zhao Wei Zhao Wei Zhao Wei Zhou Krina T Zondervan Jerome I Rotter John A Pospisilik Fernando Rivadeneira Ingrid B Borecki Panos Deloukas Timothy M Frayling Guillaume Lettre Kari E North Cecilia M Lindgren Joel N Hirschhorn Ruth J F Loos

Nat Genet 2019 Jul;51(7):1191-1192

Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-019-0447-2DOI Listing
July 2019

Association of change in cognitive function from early adulthood to middle age with risk of cause-specific mortality: the Vietnam Experience Study.

J Epidemiol Community Health 2019 08 31;73(8):712-716. Epub 2019 May 31.

Department of Epidemiology and Public Health, University College London, London, UK.

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http://dx.doi.org/10.1136/jech-2019-212377DOI Listing
August 2019