Ian C Lawrance

Ian C Lawrance

UNVERIFIED PROFILE

Are you Ian C Lawrance?   Register this Author

Register author
Ian C Lawrance

Ian C Lawrance

Publications by authors named "Ian C Lawrance"

Are you Ian C Lawrance?   Register this Author

59Publications

1692Reads

25Profile Views

Vitamin D metabolites are lower with active Crohn's disease and spontaneously recover with development of remission.

Therap Adv Gastroenterol 2019 26;12:1756284819865144. Epub 2019 Jul 26.

St Vincent's Hospital, Department of Gastroenterology, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1756284819865144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661794PMC
July 2019

Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis.

Scand J Gastroenterol 2019 Mar 23;54(3):273-280. Epub 2019 Mar 23.

a Discipline of Physiology, Adelaide Medical School , The University of Adelaide , Adelaide , South Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00365521.2019.1581253DOI Listing
March 2019

Real-world evidence for vedolizumab: Understanding the landscape.

J Gastroenterol Hepatol 2018 Sep;33 Suppl 3:28-29

Centre for Inflammatory Bowel Diseases, Saint John of God Hospital, Subiaco, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgh.14433DOI Listing
September 2018

Ultraviolet Irradiation of Skin Alters the Faecal Microbiome Independently of Vitamin D in Mice.

Nutrients 2018 Aug 11;10(8). Epub 2018 Aug 11.

Telethon Kids Institute, The University of Western Australia, Perth, WA 6008, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu10081069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116187PMC
August 2018

Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer.

Dig Dis Sci 2018 01 6;63(1):135-145. Epub 2017 Dec 6.

Discipline of Physiology, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10620-017-4876-4DOI Listing
January 2018

Cellular and Molecular Mediators of Intestinal Fibrosis.

J Crohns Colitis 2017 Dec;11(12):1491-1503

Department of Life, Health and Environmental Sciences, Gastroenterology Unit, University of L'Aquila, L'Aquila, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.crohns.2014.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885809PMC
December 2017

Efficacy of Rectal Tacrolimus for Induction Therapy in Patients With Resistant Ulcerative Proctitis.

Clin Gastroenterol Hepatol 2017 Aug 7;15(8):1248-1255. Epub 2017 Mar 7.

Department of Gastroenterology and Hepatology, Liverpool Hospital, Sydney, NSW, Australia; South Western Sydney Clinical School, University of NSW Medicine, Sydney, NSW, Australia; Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, UNSW Australia, Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2017.02.027DOI Listing
August 2017

Dysplasia and colorectal cancer surveillance in inflammatory bowel disease.

Expert Rev Gastroenterol Hepatol 2017 Aug 16;11(8):711-722. Epub 2017 May 16.

a Centre for Inflammatory Bowel Diseases , Saint John of God Hospital , Subiaco , WA , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17474124.2017.1327347DOI Listing
August 2017

Dysregulation of innate immunity in ulcerative colitis patients who fail anti-tumor necrosis factor therapy.

World J Gastroenterol 2016 Nov;22(41):9104-9116

Angela C Baird, Ian C Lawrance, Faculty of Medicine and Dentistry, School of Medicine and Pharmacology, University of Western Australia, Perth, WA 6009, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v22.i41.9104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107592PMC
November 2016

High Vitamin D-Binding Protein Concentration, Low Albumin, and Mode of Remission Predict Relapse in Crohn's Disease.

Inflamm Bowel Dis 2016 10;22(10):2456-64

*Harry Perkins Institute of Medical Research, School of Medicine and Pharmacology, University of Western Australia, Murdoch, Western Australia, Australia;†Telethon Kids Institute, University of Western Australia, Subiaco, Western Australia, Australia;‡UWA Centre for Applied Statistics, University of Western Australia, Western Australia, Crawley, Australia;§Department of Gastroenterology and Hepatology, Flinders Medical Centre, South Australia, Adelaide, Australia;‖Department of Gastroenterology and Hepatology, Royal Brisbane and Women's Hospital, Queensland, Brisbane, Australia; and¶Centre for Inflammatory Bowel Diseases, Saint John of God Hospital, Subiaco, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MIB.0000000000000894DOI Listing
October 2016

Acute severe ulcerative colitis: Changing treatment paradigms.

Authors:
Ian C Lawrance

J Gastroenterol Hepatol 2016 Jun;31 Suppl 1:16

Harry Perkins Institute of Medical Research, School of Medicine and Pharmacology, University of Western Australia, Murdoch, Western Australia, Australia; Centre for Inflammatory Bowel Diseases, Saint John of God Hospital, Subiaco, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgh.13350DOI Listing
June 2016

The multidisciplinary team.

Authors:
Ian C Lawrance

J Gastroenterol Hepatol 2016 Jun;31 Suppl 1:17

Harry Perkins Institute of Medical Research, School of Medicine and Pharmacology, University of Western Australia, Murdoch, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jgh.13351DOI Listing
June 2016

Prostaglandin E₂ and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function.

Dig Dis Sci 2015 Jun 29;60(6):1603-16. Epub 2015 Jan 29.

Fremantle Unit, School of Medicine and Pharmacology, Level 6, T Block, Fremantle Hospital, University of Western Australia, Alma Street, Fremantle, WA, 6010, Australia,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10620-015-3552-9DOI Listing
June 2015

Early investigational TNF receptor antagonists for the treatment of ulcerative colitis.

Authors:
Ian C Lawrance

Expert Opin Investig Drugs 2015 Jun 26;24(6):761-8. Epub 2015 Feb 26.

University of Western Australia, Harry Perkins Institute for Medical Research, School of Medicine and Pharmacology, Fiona Stanley Hospital , Murdoch, WA , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/13543784.2015.1020371DOI Listing
June 2015

Mechanisms of initiation and progression of intestinal fibrosis in IBD.

Scand J Gastroenterol 2015 Jan;50(1):53-65

Department of Life, Health and Environmental Sciences, Gastroenterology Unit, University of L'Aquila , L'Aquila , Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/00365521.2014.968863DOI Listing
January 2015

Results of the 4th scientific workshop of the ECCO (I): pathophysiology of intestinal fibrosis in IBD.

J Crohns Colitis 2014 Oct 14;8(10):1147-65. Epub 2014 Apr 14.

Centre for Inflammatory Bowel Diseases, Fremantle Hospital, WA, Australia; University Department of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, WA, Australia.

View Article

Download full-text PDF

Source
https://academic.oup.com/ecco-jcc/article-lookup/doi/10.1016
Publisher Site
http://dx.doi.org/10.1016/j.crohns.2014.03.008DOI Listing
October 2014

Secreted protein acidic and rich in cysteine (SPARC) exacerbates colonic inflammatory symptoms in dextran sodium sulphate-induced murine colitis.

PLoS One 2013 21;8(10):e77575. Epub 2013 Oct 21.

Centre for Inflammatory Bowel Diseases, School of Medicine and Pharmacology, University of Western Australia, Fremantle, Western Australia, Australia ; School of Veterinary and Biomedical Sciences, Murdoch University, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077575PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804578PMC
August 2014

Dietary iron enhances colonic inflammation and IL-6/IL-11-Stat3 signaling promoting colonic tumor development in mice.

PLoS One 2013 6;8(11):e78850. Epub 2013 Nov 6.

School of Medicine and Pharmacology, Fremantle Hospital, University of Western Australia, Fremantle, Western Australia, Australia ; Western Australian Institute for Medical Research, Perth, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078850PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819375PMC
August 2014

Preventing infective complications in inflammatory bowel disease.

World J Gastroenterol 2014 Aug;20(29):9691-8

Justine Mill, Ian C Lawrance, Centre for inflammatory Bowel Diseases, Fremantle Hospital, Fremantle, WA 6059, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v20.i29.9691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123359PMC
August 2014

What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?

Authors:
Ian C Lawrance

World J Gastroenterol 2014 Feb;20(5):1248-58

Ian C Lawrance, Centre for Inflammatory Bowel Diseases, Fremantle Hospital, Fremantle, WA 6059, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v20.i5.1248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921507PMC
February 2014

Crohn's disease and smoking: is it ever too late to quit?

J Crohns Colitis 2013 Dec 20;7(12):e665-71. Epub 2013 Jun 20.

Centre for Inflammatory Bowel Diseases, Fremantle Hospital, WA, Australia; University Department of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, WA, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.crohns.2013.05.007DOI Listing
December 2013

Oral tacrolimus for the treatment of refractory inflammatory bowel disease in the biologic era.

Inflamm Bowel Dis 2013 Jun;19(7):1490-8

Centre for Inflammatory Bowel Diseases, Fremantle Hospital, Fremantle, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MIB.0b013e318281f362DOI Listing
June 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Microbiota and management of inflammatory bowel disease.

Authors:
Ian C Lawrance

J Gastroenterol Hepatol 2012 Jul;27(7):1137-40

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1440-1746.2012.07163.x
Publisher Site
http://dx.doi.org/10.1111/j.1440-1746.2012.07163.xDOI Listing
July 2012

Predictors of fibrostenotic Crohn's disease.

Inflamm Bowel Dis 2011 Sep 9;17(9):2000-7. Epub 2011 Feb 9.

Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ibd.21627DOI Listing
September 2011

Serious infections in patients with inflammatory bowel disease receiving anti-tumor-necrosis-factor-alpha therapy: an Australian and New Zealand experience.

J Gastroenterol Hepatol 2010 Nov;25(11):1732-8

The Centre for Inflammatory Bowel Diseases, Fremantle Hospital, University of Western Australia, Fremantle, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1746.2010.06407.xDOI Listing
November 2010

Continuous therapy with certolizumab pegol maintains remission of patients with Crohn's disease for up to 18 months.

Clin Gastroenterol Hepatol 2010 Jul 1;8(7):600-9. Epub 2010 Feb 1.

Gastrointestinal Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4283, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2010.01.014DOI Listing
July 2010

Ecabet sodium: a potential new agent in the management of distal colitis.

Authors:
Ian C Lawrance

J Gastroenterol Hepatol 2010 Jul;25(7):1182-4

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1746.2010.06339.xDOI Listing
July 2010

Anti-tumour necrosis factor-alpha treatment for perianal Crohn's disease in Australia.

Med J Aust 2010 Apr;192(7):375-7

Department of Gastroenterology, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.

View Article

Download full-text PDF

Source
April 2010

Small bowel MRI enteroclysis or follow through: which is optimal?

World J Gastroenterol 2009 Nov;15(42):5300-6

School of Medicine and Pharmacology, University of Western Australia, T Block, Fremantle Hospital, Alma Street, Fremantle 6059, WA 6160, Australia.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776857PMC
http://dx.doi.org/10.3748/wjg.15.5300DOI Listing
November 2009

Efficacy of adalimumab for the management of inflammatory bowel disease in the clinical setting.

J Gastroenterol Hepatol 2009 Jul 12;24(7):1252-7. Epub 2009 Feb 12.

Centre for inflammatory Bowel Diseases, University of Western Australia, Fremantle Hospital, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1746.2009.05786.xDOI Listing
July 2009

Careful patient selection may improve response rates to infliximab in inflammatory bowel disease.

J Gastroenterol Hepatol 2007 Oct;22(10):1671-7

Department of Gastroenterology, Fremantle Hospital, Freemantle, Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1746.2006.04739.xDOI Listing
October 2007

Relationship between disease severity, quality of life and health-care resource use in a cross-section of Australian patients with Crohn's disease.

J Gastroenterol Hepatol 2007 Aug 7;22(8):1306-12. Epub 2007 Jun 7.

Monash University Department of Medicine and Department of Gastroenterology, Box Hill Hospital, Box Hill, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1746.2007.04930.xDOI Listing
August 2007

Maintenance therapy with certolizumab pegol for Crohn's disease.

N Engl J Med 2007 Jul;357(3):239-50

Hospital for General Internal Medicine, Christian Albrechts University, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa062897DOI Listing
July 2007

Waiting times for colonoscopy and colorectal cancer diagnosis.

Med J Aust 2007 Mar;186(6):282-5

Endoscopy Unit, Fremantle Hospital, Fremantle, WA.

View Article

Download full-text PDF

Source
March 2007

Association of intestinal granulomas with smoking, phenotype, and serology in Chinese patients with Crohn's disease.

Am J Gastroenterol 2006 May;101(5):1024-9

Faculty of Medicine, The University of New South Wales, Department of Gastroenterology, Bankstown-Lidcombe Hospital, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1572-0241.2006.00503.xDOI Listing
May 2006

A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kappa B.

Gastroenterology 2003 Dec;125(6):1750-61

Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2003.08.027DOI Listing
December 2003