Publications by authors named "Ian A Wilson"

637Publications

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.

PLoS Pathog 2020 12 4;16(12):e1009089. Epub 2020 Dec 4.

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States of America.

View Article and Find Full Text PDF
December 2020

Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity.

Immunity 2020 12 25;53(6):1272-1280.e5. Epub 2020 Nov 25.

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address:

View Article and Find Full Text PDF
December 2020

Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies.

Biochem Biophys Res Commun 2020 Oct 10. Epub 2020 Oct 10.

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA, 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA, 92037, USA; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA. Electronic address:

View Article and Find Full Text PDF
October 2020

An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain.

Cell Rep 2020 10 29;33(3):108274. Epub 2020 Sep 29.

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA. Electronic address:

View Article and Find Full Text PDF
October 2020

A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.

bioRxiv 2020 Sep 21. Epub 2020 Sep 21.

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

View Article and Find Full Text PDF
September 2020

Structural Biology of Influenza Hemagglutinin: An Amaranthine Adventure.

Viruses 2020 09 22;12(9). Epub 2020 Sep 22.

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

View Article and Find Full Text PDF
September 2020

A V1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.

Sci Adv 2020 Sep 16;6(38). Epub 2020 Sep 16.

State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Changping District, Beijing 102206, China.

View Article and Find Full Text PDF
September 2020

An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.

Proc Natl Acad Sci U S A 2020 08 20;117(31):18431-18438. Epub 2020 Jul 20.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037;

View Article and Find Full Text PDF
August 2020

Structural basis of a shared antibody response to SARS-CoV-2.

Science 2020 08 13;369(6507):1119-1123. Epub 2020 Jul 13.

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

View Article and Find Full Text PDF
August 2020