Iakes Ezkurdia

Iakes Ezkurdia

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Iakes Ezkurdia

Iakes Ezkurdia

Publications by authors named "Iakes Ezkurdia"

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Comprehensive Quantification of the Modified Proteome Reveals Oxidative Heart Damage in Mitochondrial Heteroplasmy.

Cell Rep 2018 06;23(12):3685-3697.e4

Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28049 Madrid, Spain; CIBER Cardiovascular Diseases (CIBERCV), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.080DOI Listing
June 2018

The potential clinical impact of the release of two drafts of the human proteome.

Expert Rev Proteomics 2015 23;12(6):579-93. Epub 2015 Oct 23.

d Structural Biology and Bioinformatics Programme , Spanish National Cancer Research Centre (CNIO) , Madrid , Spain.

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http://dx.doi.org/10.1586/14789450.2015.1103186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732427PMC
April 2017

Mechanism of super-assembly of respiratory complexes III and IV.

Nature 2016 11 24;539(7630):579-582. Epub 2016 Oct 24.

Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.

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http://dx.doi.org/10.1038/nature20157DOI Listing
November 2016

A novel high-content analysis tool reveals Rab8-driven cytoskeletal reorganization through Rho GTPases, calpain and MT1-MMP.

J Cell Sci 2016 Apr 3;129(8):1734-49. Epub 2016 Mar 3.

Cellomics Unit, Cell Biology & Physiology Program, Cell & Developmental Biology Area, Centro Nacional de Investigaciones Cardiovasculares CNIC, C/ Melchor Fernandez Almagro 3, Madrid E28029, Spain

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http://dx.doi.org/10.1242/jcs.174920DOI Listing
April 2016

Most highly expressed protein-coding genes have a single dominant isoform.

J Proteome Res 2015 Apr 11;14(4):1880-7. Epub 2015 Mar 11.

†Unidad de Proteómica and ‡Laboratorio de Proteómica Cardiovascular, Centro Nacional de Investigaciones Cardiovasculares, 28029 Madrid, Spain.

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http://pubs.acs.org/doi/10.1021/pr501286b
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http://dx.doi.org/10.1021/pr501286bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768900PMC
April 2015

Analyzing the first drafts of the human proteome.

J Proteome Res 2014 Aug 16;13(8):3854-5. Epub 2014 Jul 16.

‡Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro, 3, Madrid 28029, Spain.

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http://dx.doi.org/10.1021/pr500572zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334283PMC
August 2014

APPRIS: annotation of principal and alternative splice isoforms.

Nucleic Acids Res 2013 Jan 17;41(Database issue):D110-7. Epub 2012 Nov 17.

Spanish National Bioinformatics Institute (INB), Madrid 28029, Spain.

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http://dx.doi.org/10.1093/nar/gks1058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531113PMC
January 2013

Comparative proteomics reveals a significant bias toward alternative protein isoforms with conserved structure and function.

Mol Biol Evol 2012 Sep 22;29(9):2265-83. Epub 2012 Mar 22.

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre, Madrid, Spain.

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http://dx.doi.org/10.1093/molbev/mss100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424414PMC
September 2012

Targeted proteome investigation via selected reaction monitoring mass spectrometry.

J Proteomics 2012 Jun 8;75(12):3495-513. Epub 2012 May 8.

Department of Biology, Institute of Molecular Systems Biology, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jprot.2012.04.048DOI Listing
June 2012

Protein structural domains: definition and prediction.

Curr Protoc Protein Sci 2011 Nov;Chapter 2:Unit2.14

Spanish National Cancer Research Centre (CNIO)-Structural Biology and Biocomputing Programme, Madrid, Spain.

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http://dx.doi.org/10.1002/0471140864.ps0214s66DOI Listing
November 2011

Target domain definition and classification in CASP8.

Proteins 2009 ;77 Suppl 9:10-7

Structural and Computational Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1002/prot.22497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805415PMC
January 2010

Assessment of domain boundary predictions and the prediction of intramolecular contacts in CASP8.

Proteins 2009 ;77 Suppl 9:196-209

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1002/prot.22554DOI Listing
January 2010

Assessment of ligand binding residue predictions in CASP8.

Proteins 2009 ;77 Suppl 9:138-46

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1002/prot.22557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204792PMC
January 2010

Progress and challenges in predicting protein-protein interaction sites.

Brief Bioinform 2009 May 3;10(3):233-46. Epub 2009 Apr 3.

Centro Nacional de Biotechnolgia, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://bib.oxfordjournals.org/content/10/3/233.full.pdf
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http://bib.oxfordjournals.org/cgi/doi/10.1093/bib/bbp021
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http://dx.doi.org/10.1093/bib/bbp021DOI Listing
May 2009

EcID. A database for the inference of functional interactions in E. coli.

Nucleic Acids Res 2009 Jan 12;37(Database issue):D629-35. Epub 2008 Nov 12.

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre-CNIO and Computer Sciences Department, Universidad Carlos III de Madrid, Spain.

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http://dx.doi.org/10.1093/nar/gkn853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686479PMC
January 2009

Domain definition and target classification for CASP7.

Proteins 2007 ;69 Suppl 8:10-8

Genome Institute of Singapore, 138627 Singapore.

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http://dx.doi.org/10.1002/prot.21686DOI Listing
January 2008

Assessment of predictions submitted for the CASP7 domain prediction category.

Proteins 2007 ;69 Suppl 8:137-51

Structural and Biological Computation Programme, Spanish National Cancer Research Centre, Madrid, Spain.

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http://dx.doi.org/10.1002/prot.21675DOI Listing
January 2008

Domain definition and target classification for CASP6.

Proteins 2005 ;61 Suppl 7:8-18

Protein Design Group, CNB-CSIC, Calle Darwin, 28049 Cantoblanco, Spain.

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http://dx.doi.org/10.1002/prot.20717DOI Listing
May 2006

Assessment of predictions submitted for the CASP6 comparative modeling category.

Proteins 2005 ;61 Suppl 7:27-45

Protein Design Group, CNB-CSIC, Cantoblanco, Madrid, Spain.

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http://dx.doi.org/10.1002/prot.20720DOI Listing
May 2006