Iain C Macdougall

Iain C Macdougall

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Iain C Macdougall

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Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell?

Am J Nephrol 2018 13;47(2):72-83. Epub 2018 Feb 13.

Division of Cardiology, Children's Hospital Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1159/000486968DOI Listing
October 2019

Intravenous Iron Use in the Care of Patients with Kidney Disease.

Clin J Am Soc Nephrol 2019 Oct 7;14(10):1528-1530. Epub 2019 Jun 7.

Department of Renal Medicine, King's College Hospital, London, UK

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http://dx.doi.org/10.2215/CJN.00510119DOI Listing
October 2019

Restricting Red-Cell Transfusions in Cardiac Surgery: No Increase in AKI.

J Am Soc Nephrol 2019 Jul 20;30(7):1143-1144. Epub 2019 Jun 20.

Fiona Stanley Hospital, University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1681/ASN.2019050509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622416PMC
July 2019

Intravenous Iron and Maintenance Hemodialysis. Reply.

N Engl J Med 2019 06;380(24):e46

University of Glasgow, Glasgow, United Kingdom

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http://dx.doi.org/10.1056/NEJMc1902945DOI Listing
June 2019

Fatigue in Prevalent Haemodialysis Patients Predicts All-cause Mortality and Kidney Transplantation.

Ann Behav Med 2019 May;53(6):501-514

Health Psychology Section, Psychology Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5th floor Bermondsey Wing, Guy's Campus, London Bridge, London, UK.

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http://dx.doi.org/10.1093/abm/kay061DOI Listing
May 2019

HIF stabilizers in the management of renal anemia: from bench to bedside to pediatrics.

Pediatr Nephrol 2019 Mar 22;34(3):365-378. Epub 2018 Mar 22.

Department of Renal Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.1007/s00467-017-3849-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349802PMC
March 2019

Obesity and recovery from acute kidney injury (Ob AKI): a prospective cohort feasibility study.

BMJ Open 2019 Mar 20;9(3):e024033. Epub 2019 Mar 20.

Centre for Kidney Research and Innovation, University of Nottingham Faculty of Medicine and Health Sciences, Derby, UK.

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http://dx.doi.org/10.1136/bmjopen-2018-024033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528015PMC
March 2019

Treatment of anaemia in end-stage renal disease: A double-edged iron sword?

EBioMedicine 2019 Feb 17;40:31-32. Epub 2019 Jan 17.

Department of Renal Medicine, Salford Royal NHS Foundation Trust, Salford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413296PMC
February 2019

Complement Activation-Related Pseudo-Allergy: A Fresh Look at Hypersensitivity Reactions to Intravenous Iron.

Am J Nephrol 2017 29;45(1):60-62. Epub 2016 Nov 29.

Department of Renal Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.1159/000451069DOI Listing
January 2019

Intravenous Iron in Patients Undergoing Maintenance Hemodialysis.

N Engl J Med 2019 01 26;380(5):447-458. Epub 2018 Oct 26.

From the Department of Renal Medicine, King's College Hospital (I.C.M., C.W.), and University College London (D.C.W.), London, Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School, Hull (S.B.), Lister Hospital, Stevenage (K.F.), and University of Hertfordshire, Hertfordshire (K.F.), the Department of Renal Medicine, Salford Royal NHS Foundation Trust, Salford (P.A.K.), the British Heart Foundation Cardiovascular Research Centre (J.J.V.M.) and the Robertson Centre for Biostatistics (H.M., I.F.), University of Glasgow, Glasgow, Freeman Hospital, Newcastle upon Tyne (C.R.V.T.), and the Oxford Kidney Unit, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford (C.G.W.) - all in the United Kingdom; and the Division of Cardiology and Metabolism, Department of Cardiology, Berlin-Brandenburg Center for Regenerative Therapies, German Center for Cardiovascular Research partner site Berlin, Charité Universitätsmedizin Berlin, Berlin (S.D.A.).

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http://www.nejm.org/doi/10.1056/NEJMoa1810742
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http://dx.doi.org/10.1056/NEJMoa1810742DOI Listing
January 2019

Effects of Molidustat in the Treatment of Anemia in CKD.

Clin J Am Soc Nephrol 2019 01 17;14(1):28-39. Epub 2018 Dec 17.

Departments of Research and Development, and Pharmaceuticals, Bayer AG, Wuppertal, Germany.

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http://dx.doi.org/10.2215/CJN.02510218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364546PMC
January 2019

Randomized trial of intravenous iron-induced hypophosphatemia.

JCI Insight 2018 12 6;3(23). Epub 2018 Dec 6.

AMAG Pharmaceuticals, Inc., Waltham, Massachusetts, USA.

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http://dx.doi.org/10.1172/jci.insight.124486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328019PMC
December 2018

A controlled study of the effects of ferric carboxymaltose on bone and haematinic biomarkers in chronic kidney disease and pregnancy.

Nephrol Dial Transplant 2018 09;33(9):1628-1635

Department of Renal Medicine, Eastern Health, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1093/ndt/gfx310DOI Listing
September 2018

Iron therapy for managing anaemia in chronic kidney disease.

Curr Opin Nephrol Hypertens 2018 09;27(5):358-363

Department of Renal Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.1097/MNH.0000000000000436DOI Listing
September 2018

'It's when you're not doing too much you feel tired': A qualitative exploration of fatigue in end-stage kidney disease.

Br J Health Psychol 2018 05 27;23(2):311-333. Epub 2017 Dec 27.

Health Psychology Section, Psychology Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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http://dx.doi.org/10.1111/bjhp.12289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900909PMC
May 2018

Does Intragastric Balloon Treatment for Obesity in Chronic Kidney Disease Heighten Acute Kidney Injury Risk?

Am J Nephrol 2016 27;44(6):411-418. Epub 2016 Oct 27.

Department of Nutrition and Dietetics, King's College Hospital NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1159/000450765DOI Listing
January 2018

Intravenous iron: out of sight, out of mind.

Lancet Haematol 2018 01;5(1):e10-e12

Department of Renal Medicine, Kings College Hospital, London, UK.

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http://dx.doi.org/10.1016/S2352-3026(17)30230-2DOI Listing
January 2018

Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients.

Am J Nephrol 2017 25;45(3):187-199. Epub 2017 Jan 25.

Department of Nephrology, Alessandro Manzoni Hospital, Lecco, Italy.

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http://dx.doi.org/10.1159/000455166DOI Listing
December 2017

Intravenous iron therapy in patients with chronic kidney disease: recent evidence and future directions.

Clin Kidney J 2017 Dec 28;10(Suppl 1):i16-i24. Epub 2017 Nov 28.

Department of Renal Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.1093/ckj/sfx043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716151PMC
December 2017

New options for the anemia of chronic kidney disease.

Kidney Int Suppl (2011) 2017 Dec 17;7(3):157-163. Epub 2017 Nov 17.

Renal Unit, King's College Hospital, London, UK.

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http://dx.doi.org/10.1016/j.kisu.2017.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341017PMC
December 2017

Effect of Ferric Carboxymaltose on Exercise Capacity in Patients With Chronic Heart Failure and Iron Deficiency.

Circulation 2017 Oct 12;136(15):1374-1383. Epub 2017 Jul 12.

From Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands (D.J.v.V., P.v.d.M., A.A.V.); Department of Heart Diseases, Medical University, Clinical Military Hospital, Wroclaw, Poland (P.P.); Department of Cardiology, University Hospital, Brescia, Italy (M.M.); Universitätsklinikum des Saarlandes, Homburg/Saar, Germany (M.B.); I.M. Sechenov First Moscow State Medical University, Moscow, Russia (A.D.); King's College Hospital, London, United Kingdom (I.C.M.); Division of Cardiology and Metabolism, Department of Cardiology (CVK) and Berlin-Brandenburg Center for Regenerative Therapies (S.D.A.); Deutsches Zentrum für Herz-Kreislauf-Forschung, Berlin (S.D.A.); Charité Universitätsmedizin Berlin, Germany (S.D.A.); Department of Cardiology and Pneumology, University Medicine Göttingen, Germany (S.D.A.); Vifor Pharma, Glattbrugg, Switzerland (B.R., L.Z.); and Hopital Lariboisiere, University Paris Diderot, UMR-S942, France (A.C.-S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642327PMC
October 2017

IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors.

Proc Natl Acad Sci U S A 2017 07 5;114(27):7083-7088. Epub 2017 Jun 5.

Division of Transplantation Immunology and Mucosal Biology, Medical Research Council Centre for Transplantation, Faculty of Life Sciences and Medicine, King's College London, London SE5 9RS, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1620835114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502598PMC
July 2017

Examining the efficacy of social-psychological interventions for the management of fatigue in end-stage kidney disease (ESKD): a systematic review with meta-analysis.

Health Psychol Rev 2017 06 6;11(2):197-216. Epub 2017 Mar 6.

a Health Psychology Section, Psychology Department , Institute of Psychiatry, Psychology and Neuroscience, King's College London , London , UK.

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http://dx.doi.org/10.1080/17437199.2017.1298045DOI Listing
June 2017

The role of psychological factors in fatigue among end-stage kidney disease patients: a critical review.

Clin Kidney J 2017 Feb 20;10(1):79-88. Epub 2016 Dec 20.

Health Psychology Section, Psychology Department, Institute of Psychiatry, Psychology, & Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1093/ckj/sfw113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469558PMC
February 2017

Oral Iron Therapy: After Three Centuries, It Is Time for a Change.

Am J Kidney Dis 2016 11;68(5):665-666

King's College Hospital, London, United Kingdom.

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http://dx.doi.org/10.1053/j.ajkd.2016.08.007DOI Listing
November 2016

Peginesatide for the treatment of anemia due to chronic kidney disease - an unfulfilled promise.

Expert Opin Drug Saf 2016 Oct 23;15(10):1421-6. Epub 2016 Aug 23.

d Department of Renal Medicine , King's College Hospital , London , UK.

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http://dx.doi.org/10.1080/14740338.2016.1218467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286458PMC
October 2016

Measuring fatigue in haemodialysis patients: The factor structure of the Chalder Fatigue Questionnaire (CFQ).

J Psychosom Res 2016 May 4;84:81-83. Epub 2016 Apr 4.

Health Psychology Section, Psychology Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychores.2016.03.124DOI Listing
May 2016

Iron Treatment Strategies in Nondialysis CKD.

Semin Nephrol 2016 03;36(2):99-104

Department of Renal Medicine, King's College Hospital, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semnephrol.2016.02.003DOI Listing
March 2016

Iron deficiency anaemia.

Lancet 2016 Feb 24;387(10021):907-16. Epub 2015 Aug 24.

Department of Hepato-Gastroenterology and Inserm U954, University Hospital of Nancy, Lorraine University, Vandoeuvre-lès-Nancy, France. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(15)60865-0DOI Listing
February 2016

Risk for chronic kidney disease increases with obesity: Health Survey for England 2010.

Public Health Nutr 2015 Dec 6;18(18):3349-54. Epub 2015 Mar 6.

1Department of Nutrition and Dietetics,King's College Hospital,Denmark Hill,London SE5 9RS,UK.

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http://dx.doi.org/10.1017/S1368980015000488DOI Listing
December 2015

New data on the safety of IV iron-but why the discrepancy with FIND-CKD?

Kidney Int 2015 Dec;88(6):1445-1446

Department of Renal Medicine, Gosford Hospital, Gosford, Australia.

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http://dx.doi.org/10.1038/ki.2015.302DOI Listing
December 2015

Participation in a Structured Weight Loss Program and All-Cause Mortality and Cardiovascular Morbidity in Obese Patients With Chronic Kidney Disease.

J Ren Nutr 2015 Nov 2;25(6):472-9. Epub 2015 Jul 2.

School of Medicine, King's College London, London, UK; Department of Renal Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.1053/j.jrn.2015.05.001DOI Listing
November 2015

Supplemental iron via dialysate: a novel mode of delivery for hemodialysis patients.

Kidney Int 2015 Nov;88(5):946-9

Department of Renal Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.1038/ki.2015.260DOI Listing
November 2015

Longitudinal assessments of erythropoietin-stimulating agent responsiveness and the association with specific clinical outcomes in dialysis patients.

Nephron Clin Pract 2014 6;128(1-2):147-52. Epub 2014 Nov 6.

Division of Nephrology, Department of Medicine, University Hospital Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1159/000367975DOI Listing
July 2015

Iron therapy for the treatment of iron deficiency in chronic heart failure: intravenous or oral?

Eur J Heart Fail 2015 Mar 30;17(3):248-62. Epub 2015 Jan 30.

Department of Cardiology, King's College Hospital, London, UK.

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http://dx.doi.org/10.1002/ejhf.236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671256PMC
March 2015

Desmopressin use prior to renal transplant biopsy-does it fit?

Clin Kidney J 2014 Dec 29;7(6):602-4. Epub 2014 Oct 29.

Renal Unit , King's College Hospital , London , UK.

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http://dx.doi.org/10.1093/ckj/sfu110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389145PMC
December 2014

Obesity does not influence hepcidin and hemojuvelin levels in hemodialysis patients.

Nephron Clin Pract 2013 12;124(3-4):159-66. Epub 2013 Dec 12.

Department of Renal Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1159/000355545DOI Listing
October 2014

Intra-dialytic exercise training: a pragmatic approach.

J Ren Care 2014 Sep 28;40(3):219-26. Epub 2014 Jul 28.

Department of Renal Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.1111/jorc.12080DOI Listing
September 2014

The authors reply.

Kidney Int 2014 Jul;86(1):211

Renal Unit, King's College Hospital, London, UK.

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http://dx.doi.org/10.1038/ki.2014.150DOI Listing
July 2014

Safety of intravenous iron formulations: facts and folklore.

Blood Transfus 2014 Jul;12(3):296-300

Department of Nephrology, King's College Hospital, London, United Kingdom.

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http://dx.doi.org/10.2450/2014.0094-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111808PMC
July 2014

Unusual presentation of aortic dissection with bilateral testicular pain and rapidly deteriorating renal function.

Urology 2014 May 16;83(5):989-91. Epub 2013 Oct 16.

Department of Renal Medicine, King's College Hospital, London, United Kingdom.

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http://dx.doi.org/10.1016/j.urology.2013.08.027DOI Listing
May 2014

Intravenous iron therapy in non-dialysis CKD patients.

Nephrol Dial Transplant 2014 Apr 5;29(4):717-20. Epub 2013 Dec 5.

Department of Renal Medicine, Renal Unit, King's College Hospital, London, UK.

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http://dx.doi.org/10.1093/ndt/gft419DOI Listing
April 2014

A randomized comparison of ferumoxytol and iron sucrose for treating iron deficiency anemia in patients with CKD.

Clin J Am Soc Nephrol 2014 Apr 23;9(4):705-12. Epub 2014 Jan 23.

Department of Renal Medicine, King's College Hospital, London, United Kingdom;, †AMAG Pharmaceuticals, Inc., Lexington, Massachusetts;, ‡Nephrology Center Karlstr, Dusseldorf, Germany, §Greenville Kidney Care, LLC, Greenville, South Carolina.

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http://dx.doi.org/10.2215/CJN.05320513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974353PMC
April 2014

GDF15 is related to anemia and hepcidin in kidney allograft recipients.

Nephron Clin Pract 2013 22;123(1-2):112-7. Epub 2013 Jun 22.

Department of Nephrology and Transplantology, Medical University, Bialystok, Poland.

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http://dx.doi.org/10.1159/000351810DOI Listing
March 2014

Intravenous iron supplementation in distance runners with low or suboptimal ferritin.

Med Sci Sports Exerc 2014 Feb;46(2):376-85

1National Institute of Sports Studies, University of Canberra, Canberra, AUSTRALIA; 2Australian Institute of Sport, Canberra, AUSTRALIA; and 3King's College Hospital, London, UNITED KINGDOM.

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http://dx.doi.org/10.1249/MSS.0b013e3182a53594DOI Listing
February 2014

Interventions for erythropoietin-resistant anaemia in dialysis patients.

Cochrane Database Syst Rev 2013 Aug 26(8):CD006861. Epub 2013 Aug 26.

Department of Nephrology, Princess Alexandra Hospital, Woolloongabba, QLD, Australia, 4102.

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http://dx.doi.org/10.1002/14651858.CD006861.pub3DOI Listing
August 2013

Guideline for the laboratory diagnosis of functional iron deficiency.

Br J Haematol 2013 Jun 10;161(5):639-48. Epub 2013 Apr 10.

Derriford Hospital, Plymouth, UK.

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http://dx.doi.org/10.1111/bjh.12311DOI Listing
June 2013

An analysis of the health service efficiency and patient experience with two different intravenous iron preparations in a UK anaemia clinic.

J Med Econ 2013 10;16(1):108-14. Epub 2012 Oct 10.

Department of Renal Medicine, King's College Hospital, London, UK.

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http://dx.doi.org/10.3111/13696998.2012.731458DOI Listing
May 2013

Effect of red cell transfusions on future kidney transplantation.

Clin J Am Soc Nephrol 2013 May 18;8(5):852-60. Epub 2012 Oct 18.

Universidad Panamericana School of Medicine, Mexico City, Mexico.

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http://dx.doi.org/10.2215/CJN.00020112DOI Listing
May 2013

How important is transfusion avoidance in 2013?

Nephrol Dial Transplant 2013 May 13;28(5):1092-9. Epub 2013 Mar 13.

Department of Renal Medicine, King's College Hospital, London SE5 9RS, UK.

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http://ndt.oxfordjournals.org/content/early/2013/03/13/ndt.g
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http://ndt.oxfordjournals.org/cgi/doi/10.1093/ndt/gfs575
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http://dx.doi.org/10.1093/ndt/gfs575DOI Listing
May 2013

Peginesatide for anemia in chronic kidney disease.

N Engl J Med 2013 04;368(16):1553-4

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http://dx.doi.org/10.1056/NEJMc1302314DOI Listing
April 2013

Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives.

Eur Heart J 2013 Mar 25;34(11):816-29. Epub 2012 Oct 25.

Department of Heart Diseases, Wroclaw Medical University, ul Weigla 5, 50-981 Wroclaw, Poland.

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https://academic.oup.com/eurheartj/article-lookup/doi/10.109
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http://dx.doi.org/10.1093/eurheartj/ehs224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596759PMC
March 2013

Iron status in patients with chronic heart failure.

Eur Heart J 2013 Mar 23;34(11):827-34. Epub 2012 Nov 23.

Laboratory for Applied Research of Cardiovascular System, Department of Heart Diseases, Faculty of Health Sciences, Wroclaw Medical University, ul. Weigla 5, 50-981 Wroclaw, Poland.

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https://academic.oup.com/eurheartj/article-lookup/doi/10.109
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http://dx.doi.org/10.1093/eurheartj/ehs377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697803PMC
March 2013

Use of intravenous iron supplementation in chronic kidney disease: an update.

Iran J Kidney Dis 2013 Jan;7(1):9-22

Department of Renal Medicine, King's College Hospital, London, UK.

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January 2013

Evaluation of a pragmatic exercise rehabilitation programme in chronic kidney disease.

Nephrol Dial Transplant 2012 Oct 10;27 Suppl 3:iii126-34. Epub 2012 Jul 10.

King's College Hospital, London, UK.

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http://dx.doi.org/10.1093/ndt/gfs272DOI Listing
October 2012

Intra-individual variability of serum hepcidin-25 in haemodialysis patients using mass spectrometry and ELISA.

Nephrol Dial Transplant 2012 Oct 19;27(10):3923-9. Epub 2012 Jul 19.

Department of Nephrology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfs164DOI Listing
October 2012

Compliance with a structured weight loss program is associated with reduced systolic blood pressure in obese patients with chronic kidney disease.

Am J Hypertens 2012 Sep 21;25(9):1024-9. Epub 2012 Jun 21.

Diabetes and Nutritional Sciences Division, King's College London, London, UK.

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http://dx.doi.org/10.1038/ajh.2012.80DOI Listing
September 2012