Iacopo Sardi

Iacopo Sardi

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Iacopo Sardi

Iacopo Sardi

Publications by authors named "Iacopo Sardi"

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A microRNA profile of pediatric glioblastoma: The role of NUCKS1 upregulation.

Mol Clin Oncol 2019 Mar 2;10(3):331-338. Epub 2019 Jan 2.

Neuro-Oncology Unit, Department of Pediatric Oncology, Meyer Children's University Hospital, I-50139 Florence, Italy.

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http://www.spandidos-publications.com/10.3892/mco.2019.1795
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http://dx.doi.org/10.3892/mco.2019.1795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388501PMC
March 2019

Combined Treatment with Doxorubicin and Rapamycin Is Effective against In Vitro and In Vivo Models of Human Glioblastoma.

J Clin Med 2019 Mar 9;8(3). Epub 2019 Mar 9.

Neuro-oncology Unit, Department of Pediatric Oncology, Meyer Children's Hospital, 50139 Florence, Italy.

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http://dx.doi.org/10.3390/jcm8030331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462908PMC
March 2019

Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors.

Cancer Gene Ther 2018 Nov 22. Epub 2018 Nov 22.

Department of Medical and Surgical Sciences for Children and Adults, Division of Oncology, University-Hospital of Modena and Reggio Emilia, Modena, Italy.

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http://dx.doi.org/10.1038/s41417-018-0062-xDOI Listing
November 2018

Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier.

Int J Mol Sci 2018 Sep 22;19(10). Epub 2018 Sep 22.

Neuro-oncology Unit, Department of Pediatric Oncology, Meyer Children's Hospital, Florence, 50139, Italy.

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http://dx.doi.org/10.3390/ijms19102879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213072PMC
September 2018

Sirolimus in Infants with Multiple Cardiac Rhabdomyomas Associated with Tuberous Sclerosis Complex.

Case Rep Oncol 2018 May-Aug;11(2):425-430. Epub 2018 Jun 28.

Neuro-Oncology Unit, Department of Pediatric Oncology, Meyer Children's University Hospital, Florence, Italy.

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https://www.karger.com/Article/FullText/490662
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http://dx.doi.org/10.1159/000490662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062714PMC
June 2018

Alveolar rhabdomyosarcoma in a 6-month-old boy.

Arch Dis Child 2018 01 13;103(1):95. Epub 2017 May 13.

Department of Health Sciences, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1136/archdischild-2016-312547DOI Listing
January 2018

The dawn of "immune-revolution" in children: early experiences with checkpoint inhibitors in childhood malignancies.

Cancer Chemother Pharmacol 2017 Dec 24;80(6):1047-1053. Epub 2017 Oct 24.

Department of Pediatric Oncology, Hematology, and Transplants, Anna Meyer Children's Hospital, Florence, Italy.

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http://dx.doi.org/10.1007/s00280-017-3450-2DOI Listing
December 2017

Developing drugs in cancer-related bone pain.

Crit Rev Oncol Hematol 2017 Nov 25;119:66-74. Epub 2017 Aug 25.

Medical Oncology Unit, Campus Biomedico University Hospital, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2017.08.005DOI Listing
November 2017

Spinal cord involvement in two children with posterior reversible encephalopathy syndrome.

CNS Oncol 2017 10 6;6(4):287-290. Epub 2017 Oct 6.

Neuro-Oncology Unit, Department of Pediatric Oncology, Anna Meyer Children's University Hospital, Florence 50139, Italy.

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http://dx.doi.org/10.2217/cns-2017-0003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004885PMC
October 2017

Role of eculizumab in a pediatric refractory gemcitabine-induced thrombotic microangiopathy: a case report.

J Med Case Rep 2017 Jul 27;11(1):209. Epub 2017 Jul 27.

Neuro-Oncology Unit, Department of Pediatric Oncology, Meyer Children's Hospital, Viale G. Pieraccini 24, 50139, Florence, Italy.

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http://dx.doi.org/10.1186/s13256-017-1373-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530476PMC
July 2017

Brain tumors in Li-Fraumeni syndrome: a commentary and a case of a gliosarcoma patient.

Future Oncol 2017 Jan 15;13(1):9-12. Epub 2016 Aug 15.

Neuro-Oncology Unit, Department of Pediatric Oncology, Meyer Children's University Hospital, Florence, Italy.

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http://dx.doi.org/10.2217/fon-2016-0236DOI Listing
January 2017

Molecular characterization of paediatric glioneuronal tumours with neuropil-like islands: a genome-wide copy number analysis.

Am J Cancer Res 2016 1;6(12):2910-2918. Epub 2016 Dec 1.

Medical Genetics Unit, Meyer Children's University HospitalViale Pieraccini 2450139, Florence, Italy; Medical Genetics Unit, Department of Clinical and Experimental Biomedical Sciences "Mario Serio", University of FlorenceViale Morgagni 5050134, Florence, Italy (S.G.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199764PMC
December 2016

Final results of the second prospective AIEOP protocol for pediatric intracranial ependymoma.

Neuro Oncol 2016 10 18;18(10):1451-60. Epub 2016 May 18.

Department of Pediatrics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (M.M., L.B., V.B., E.S.); Department of Medical Statistics, Biometry, and Bioinformatics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (R.M.); Pediatric Radiotherapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (L.G., E.P., B.D.); Department of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (G.C.); Department of Radiological, Oncological, and Anatomo-Pathological Sciences, Sapienza University, Rome, Italy (F.G., M.A.); Department of Neurology and Psychiatry, Sapienza University, Rome, Italy (F.R.B.); IRCCS Neuromed, Pozzilli, Italy (F.G.); Laboratory of Genetics, Pathology Unit, S. Anna General Hospital, Como, Italy (P.M.); Neurosurgery Department, IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (P.F., L.V.); Pathology Unit, IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (B.P.); Department of Pediatric Onco-Hematology, Regina Margherita Children's Hospital, Torino, Italy (D.B.); Department of Neurosurgery, Regina Margherita Children's Hospital, Torino, Italy (P.P.); Radiotherapy Unit, Regina Margherita Children's Hospital, Torino, Italy (A.M.); Istituto Giannina Gaslini, Genova, Italy (M.L.G., A.C.); Department of Neuro-oncology, Ospedale Pediatrico Meyer, Firenze, Italy (I.S.); Neurosurgery Unit, Ospedale Pediatrico Meyer, Firenze, Italy (L.G.); Pediatric Oncology Unit, Padova University, Padova, Italy (E.V.); Radiotherapy Department, IOV-IRCCS, Padova, Italy (G.S.); Department of Radiation Oncology, Careggy Hospital, Firenze, Italy (S.S.); Pathology Unit, Careggy Hospital, Firenze, Italy (A.B.); Department of Pediatric Radiotherapy, CRO, Aviano, Italy (M.M.); Department of Pediatric Oncology, Ospedale Santobono-Pausillipon, Napoli, Italy (L.Q.); Neurosurgery Unit, Ospedale Santobono-Pausillipon, Napoli, Italy (G.C.); Department of Radiation Oncology, IRCCS San Martino IST, National Cancer Research Institute, Ge

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http://dx.doi.org/10.1093/neuonc/now108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035526PMC
October 2016

Two-Step Approach for Persisting Pain: Learning From Children.

J Clin Oncol 2016 10;34(29):3580

Anna Meyer Children's University Hospital, Florence, Italy.

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http://dx.doi.org/10.1200/JCO.2016.66.5802DOI Listing
October 2016

Reply to Prof Ian J. Cohen.

Cancer Chemother Pharmacol 2016 07 23;78(1):219-20. Epub 2016 May 23.

Neuro-Oncology Unit, Department of Pediatric Oncology, Anna Meyer Children's University Hospital, Florence, Italy.

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http://dx.doi.org/10.1007/s00280-016-3061-3DOI Listing
July 2016

A successful case of an anaplastic meningioma treated with chemotherapy for soft tissue sarcomas.

CNS Oncol 2016 Jul 26;5(3):131-6. Epub 2016 May 26.

Neuro-Oncology Unit, Department of Pediatric Oncology, Anna Meyer Children's University Hospital, Florence, Italy.

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http://dx.doi.org/10.2217/cns-2016-0005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042637PMC
July 2016

Pharmacokinetics of high-dose methotrexate in infants aged less than 12 months treated for aggressive brain tumors.

Cancer Chemother Pharmacol 2016 Apr 17;77(4):857-64. Epub 2016 Mar 17.

Neuro-Oncology Unit, Department of Pediatric Oncology, Meyer Children's University Hospital, Florence, Italy.

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http://dx.doi.org/10.1007/s00280-016-3008-8DOI Listing
April 2016

The Use of Anthracyclines for Therapy of CNS Tumors.

Anticancer Agents Med Chem 2015 ;15(6):721-7

Neuro-Oncology Unit, Department of Paediatric Medicine, Meyer Children's Hospital. Viale G. Pieraccini 24, 50139 Florence, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997942PMC
March 2016

Prolonged exposure to doxorubicin after radiotherapy in glioblastoma.

Authors:
Iacopo Sardi

Future Oncol 2016 Mar 22;12(5):581-3. Epub 2016 Jan 22.

Neuro-Oncology Unit, Department of Pediatric Oncology, Meyer Children's University Hospital, Florence, Italy.

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http://dx.doi.org/10.2217/fon.15.354DOI Listing
March 2016

An infant with hyperalertness, hyperkinesis, and failure to thrive: a rare diencephalic syndrome due to hypothalamic anaplastic astrocytoma.

BMC Cancer 2015 Sep 4;15:616. Epub 2015 Sep 4.

Neuro-oncology Unit, Department of Paediatric Medicine, Anna Meyer Children's University Hospital and Department of Health Sciences, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1186/s12885-015-1626-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559913PMC
September 2015

Absence of human cytomegalovirus infection in childhood brain tumors.

Am J Cancer Res 2015 15;5(8):2476-83. Epub 2015 Jul 15.

Department of Paediatrics, Neuro-oncology Unit, Meyer Children's Hospital and Department of Health Sciences, University of Florence Florence, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568783PMC
September 2015

Delivery of doxorubicin across the blood-brain barrier by ondansetron pretreatment: a study in vitro and in vivo.

Cancer Lett 2014 Oct 29;353(2):242-7. Epub 2014 Jul 29.

Second Medical Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, Florence University, Florence, Italy.

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http://dx.doi.org/10.1016/j.canlet.2014.07.018DOI Listing
October 2014

Successful treatment of metastatic βHCG-secreting germ cell tumor occurring 3 years after total resection of a pineal mature teratoma.

Eur J Pediatr 2014 Aug 21;173(8):1011-5. Epub 2014 Feb 21.

Neuro-Oncology Unit, Department of Paediatric Medicine, Meyer Children's University Hospital, viale G. Pieraccini 24, 50139, Florence, Italy.

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http://dx.doi.org/10.1007/s00431-014-2282-xDOI Listing
August 2014

Genome-wide copy number analysis in pediatric glioblastoma multiforme.

Am J Cancer Res 2014 26;4(3):293-303. Epub 2014 May 26.

Medical Genetics Unit, Meyer Children's University Hospital Florence, Italy ; Department of Clinical and Experimental Biomedical Sciences "Mario Serio", University of Florence Florence, Italy ; FiorGen Foundation for Pharmacogenomics Sesto Fiorentino, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065410PMC
June 2014

Low-dose cisplatin-etoposide regimen for patients with optic pathway glioma: a report of four cases and literature review.

Neuropediatrics 2014 Feb 22;45(1):42-9. Epub 2013 Nov 22.

Neuro-oncology Unit, Department of Pediatrics, Meyer Children's Hospital, Florence, Italy.

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http://dx.doi.org/10.1055/s-0033-1360482DOI Listing
February 2014

Pharmacological modulation of blood-brain barrier increases permeability of doxorubicin into the rat brain.

Am J Cancer Res 2013 14;3(4):424-32. Epub 2013 Aug 14.

Department of Paediatric Medicine, Neuro-oncology Unit, Anna Meyer Children's University Hospital Florence, Italy.

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http://www.ajcr.us/files/ajcr0000205.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744021PMC
August 2013

Successful treatment with a low-dose cisplatin--etoposide regimen for patients with diencephalic syndrome.

J Neurooncol 2012 Sep 21;109(2):375-83. Epub 2012 Jun 21.

Department of Pediatric Hematology Oncology, A.O.U. Meyer Children's Hospital, viale G.Pieraccini 24, 50139, Florence, Italy.

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http://dx.doi.org/10.1007/s11060-012-0903-7DOI Listing
September 2012

Dedifferentiated peripheral chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of four cases.

Virchows Arch 2012 Mar 16;460(3):335-42. Epub 2012 Feb 16.

Division of Anatomic Pathology, Department of Critical Care Medicine and Surgery, University of Florence Medical School, Viale G.B. Morgagni 85, 50134 Florence, Italy.

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http://dx.doi.org/10.1007/s00428-012-1206-2DOI Listing
March 2012

Morphine facilitates doxorubicin penetration in the central nervous system: a new prospect for therapy of brain tumors.

Authors:
Iacopo Sardi

J Neurooncol 2011 Sep 14;104(2):619-20. Epub 2011 Jan 14.

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http://dx.doi.org/10.1007/s11060-010-0518-9DOI Listing
September 2011

Plasmacytoid urothelial carcinoma of the urinary bladder: clinicopathologic, immunohistochemical, ultrastructural, and molecular analysis of a case series.

Hum Pathol 2011 Aug 21;42(8):1149-58. Epub 2011 Feb 21.

Division of Histology and Molecular Diagnostics, University Hospital Careggi, Viale G.B. Morgagni, Florence, Italy 50134.

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http://dx.doi.org/10.1016/j.humpath.2010.11.011DOI Listing
August 2011

Detection of doxorubicin hydrochloride accumulation in the rat brain after morphine treatment by mass spectrometry.

Cancer Chemother Pharmacol 2011 Jun 25;67(6):1333-40. Epub 2010 Aug 25.

Department of Onco-Hematology and Neuro-Surgery Units, A Meyer Children's Hospital, viale G Pieraccini 24, 50139 Florence, Italy.

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http://dx.doi.org/10.1007/s00280-010-1429-3DOI Listing
June 2011

Tumour suppressor gene TP53 mutations in atypical vascular lesions of breast skin following radiotherapy.

Histopathology 2011 Feb 16;58(3):455-66. Epub 2011 Feb 16.

Division of Pathological Anatomy, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1111/j.1365-2559.2011.03770.xDOI Listing
February 2011

Merlin expression in pediatric anaplastic ependymomas real time PCR study.

Fetal Pediatr Pathol 2010 ;29(4):245-54

Department of Human Pathology and Oncology, University of Florence, Morgagni 85, Florence, Italy.

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http://dx.doi.org/10.3109/15513811003789644DOI Listing
September 2010

Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors.

Oncol Rep 2009 Oct;22(4):773-9

Department of Pediatric Hematology-Oncology, University of Florence, A.O.U. Meyer Children's Hospital, 50139 Florence, Italy.

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http://dx.doi.org/10.3892/or_00000499DOI Listing
October 2009

Pediatric brain tumors: mutations of two dioxygenases (hABH2 and hABH3) that directly repair alkylation damage.

J Neurooncol 2009 Sep 17;94(2):195-201. Epub 2009 Mar 17.

Onco-Hematology Unit, Department of Pediatrics, Florence Medical School, A. Meyer Children's Hospital, viale Pieraccini 24, 50139, Florence, Italy.

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http://dx.doi.org/10.1007/s11060-009-9837-0DOI Listing
September 2009

Monotherapy with thalidomide for treatment of spinal cord hemangioblastomas in a patient with von Hippel-Lindau disease.

Pediatr Blood Cancer 2009 Sep;53(3):464-7

Department of Pediatric Hematology-Oncology, A.U.O. Anna Meyer Children's Hospital, Florence, Italy.

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http://dx.doi.org/10.1002/pbc.22065DOI Listing
September 2009

Pediatric sinonasal neuroendocrine carcinoma after treatment of retinoblastoma.

Hum Pathol 2009 May 20;40(5):750-5. Epub 2009 Jan 20.

Department of Human Pathology and Oncology, University of Florence, 50134 Florence, Italy.

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http://dx.doi.org/10.1016/j.humpath.2008.09.018DOI Listing
May 2009

Teratoid hepatoblastoma.

Fetal Pediatr Pathol 2008 ;27(6):274-81

Department of Human Pathology and Oncology, Careggi Hospital, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1080/15513810802448100DOI Listing
February 2009

Intracerebral atypical presentation of echinococcosis in a child.

Pediatr Neurosurg 2008 13;44(4):350-2. Epub 2008 Jun 13.

Division of Neurosurgery, A. Meyer Children's Hospital, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1159/000138376DOI Listing
September 2008

Pineal germinoma morphological features in a liquid-based cerebrospinal fluid sample.

Diagn Cytopathol 2008 Sep;36(9):645-6

Department of Biomedicine, Careggi Hospital, Florence, Italy.

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http://dx.doi.org/10.1002/dc.20870DOI Listing
September 2008

Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.

Oncol Rep 2008 May;19(5):1219-23

Neuro-surgery Units, Department of Neurosurgery, University of Florence Medical School, The A. Meyer Children's Hospital, Florence 50132, Italy.

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May 2008

Emerging treatments and gene expression profiling in high-risk medulloblastoma.

Paediatr Drugs 2007 ;9(2):81-96

Department of Pediatrics, Onco-hematology and Neuro-surgery Units, University of Florence Medical School, A. Meyer Children's Hospital, Florence, Italy.

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http://dx.doi.org/10.2165/00148581-200709020-00002DOI Listing
June 2007

Microsatellite instability as an indicator of malignant progression in laryngeal premalignancy.

Head Neck 2006 Aug;28(8):730-9

Oncohaematology Unit, Department of Pediatrics, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/hed.20390DOI Listing
August 2006

Clonality analysis of pediatric multiple tumors: two case reports and laboratory investigation.

J Pediatr Hematol Oncol 2006 Apr;28(4):241-8

Department of Pediatrics, Medical Genetics Units, Florence University Medical School at the A. Meyer Children's Hospital, via Luca Giordano 13, 50132 Florence, Italy.

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http://dx.doi.org/10.1097/01.mph.0000212909.91770.72DOI Listing
April 2006

Qualitative and quantitative analysis of angiogenetic factors in transitional cell bladder carcinoma: relationship with clinical course at 10 years follow-up.

Oncol Rep 2005 Jul;14(1):251-5

Department of Urology, University of Florence, Viale Pieraccini 18, 50139 Florence, Italy.

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July 2005

Loss of heterozygosity and p53 polymorphism Pro72Arg in a young patient with medulloblastoma.

Oncol Rep 2003 May-Jun;10(3):773-5

Unita di Oncoematologia, Ospedale Pediatrico A. Meyer, I-50132 Florence, Italy.

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December 2003

Stomal recurrence following total laryngectomy: clinical and molecular analysis of a series.

Ann Otol Rhinol Laryngol 2003 Jul;112(7):594-9

Department of Oto-neuro-ophthalmologic Surgical Sciences, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1177/000348940311200704DOI Listing
July 2003

Correlation between nitric oxide and cyclooxygenase-2 pathways in head and neck squamous cell carcinomas.

Biochem Biophys Res Commun 2002 Dec;299(4):517-24

Department of Oto-Neuro-Ophthalmologic Surgery, University of Florence Medical School, 50134 Florence, Italy.

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http://dx.doi.org/10.1016/s0006-291x(02)02683-9DOI Listing
December 2002

Molecular profiling of high-risk neuroblastoma by cDNA array.

Int J Mol Med 2002 May;9(5):541-5

Unita di Oncoematologia, Ospedale Pediatrico A. Meyer, via L. Giordano 13, 50132 Florence, Italy.

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May 2002

The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line.

Hepatology 2002 Apr;35(4):843-52

Department of Internal Medicine, School of Medicine, University of Florence, Azienda Ospedaliera Careggi, Florence, Italy.

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http://doi.wiley.com/10.1053/jhep.2002.32469
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http://dx.doi.org/10.1053/jhep.2002.32469DOI Listing
April 2002

Inducible nitric oxide synthase expression in laryngeal neoplasia: correlation with angiogenesis.

Head Neck 2002 Jan;24(1):16-23

Department of Human Pathology and Oncology, University of Florence, Viale G. B. Morgagni 85, 50134 Florence, Italy.

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http://dx.doi.org/10.1002/hed.10045DOI Listing
January 2002