Publications by authors named "Iñaki Navarro-Castellanos"

5 Publications

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Probable Case of Vertical Transmission of SARS-CoV-2 in a Newborn in Mexico.

Neonatology 2021 May 6:1-4. Epub 2021 May 6.

Pediatric Cardiology Department, CHU Sainte-Justine, Université de Montréal, Montreal, Québec, Canada.

Background: Much remains unknown about the transmission of the SARS-CoV-2 virus. Pregnant women are considered part of the risk population, and vertical transmission of other coronaviruses has been suggested; however, this type of transmission in SARS-CoV-2 is believed to be unlikely.

Case Report: A newborn delivered in term via cesarean section to an asymptomatic but COVID-19-positive 35-year-old woman started with respiratory distress in the first 30 min of life. A chest radiograph revealed pneumothorax and ground glass opacities. Ventilatory support with continuous positive airway pressure was needed. Given the respiratory failure and the positive test from the mother, the patient was sampled for SARS-CoV-2 (RT-PCR) at minute 30 of life, with a positive result reported at 36 h of life. No complications had been present during pregnancy, and cardiac screening and blood cultures revealed no other etiologies.

Conclusion: Vertical transmission was highly likely in this case. Clinicians should be alert and report similar cases.
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http://dx.doi.org/10.1159/000514710DOI Listing
May 2021

Letter by Navarro Castellanos and Dahdah Regarding Article, "Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic".

Circulation 2021 03 8;143(10):e759-e760. Epub 2021 Mar 8.

Pediatric Cardiology Department, CHU-Saint Justine, Université de Montréal, Quebec, Canada.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.049239DOI Listing
March 2021

Supravalvular and Valvular Pulmonary Stenosis: Predictive Features and Responsiveness to Percutaneous Dilation.

Pediatr Cardiol 2021 Apr 19;42(4):814-820. Epub 2021 Jan 19.

Division of Pediatric Cardiology, CHU Sainte-Justine, 3175, Côte Sainte-Catherine, Montreal, QC, H3T 1C5, Canada.

Supravalvular pulmonary stenosis (SVPS) is considered a rare form of pulmonary stenosis (PS) and represents both a diagnostic and therapeutic challenge. There currently exist no reliable echocardiographic criteria to accurately predict the supravalvular form. The aims of the study were to describe the response to treatment of the different PS presentations and to outline the diagnostic capacity of echocardiogram to differentiate the SVPS from valvular PS (VPS). This retrospective study included 106 patients who underwent percutaneous angioplasty between 2006 and 2017. Interventional outcomes of patients with SVPS were compared to those of patients with VPS. Diagnosis of VPS vs. SVPS by echocardiogram was compared to diagnosis obtained by angiogram. Echocardiogram yielded a sensitivity of 56%, a specificity of 82.5%, a positive predictive value of 50%, and a negative predictive value of 85.7%. Patients with SVPS had a significantly smaller pulmonary artery to pulmonary valve (PA:PV) ratio. At 6-12 months of follow-up, the VPS group had a mean right ventricular to pulmonary artery (RV-PA) gradient of 21.68 ± 19.85 mmHg compared to 45.27 ± 24.58 mmHg in the SVPS group. Patients with SVPS had a higher rate of reintervention than patients with VPS (32% vs. 6.2%, p < 0.001). There was no difference in major complications between groups, whereas VPS patients had a higher proportion of pulmonary insufficiency. Percutaneous angioplasty for PS is less effective in patients with a supravalvular component. A better understanding of the underlying histopathology of different PS subtypes could lead to development of different techniques to improve outcomes, with fewer reinterventions, in this population.
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http://dx.doi.org/10.1007/s00246-021-02545-wDOI Listing
April 2021

Letter to the Editor concerning the article: "Comparison of drug eluting versus bare metal stents".

Catheter Cardiovasc Interv 2020 Jul 2. Epub 2020 Jul 2.

Department Pediatric Cardiology, CHU-Saint Justine, Université de Montréal, Montreal, QC, Canada.

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http://dx.doi.org/10.1002/ccd.29135DOI Listing
July 2020

Combining Adobe Forms and Dropbox to Obtain a Low-Cost Electronic Data Collection System.

Telemed J E Health 2019 03 22;25(3):250-256. Epub 2018 Jun 22.

2 Clinical Services, National Institute of Psychiatry "Ramón de la Fuente Muñíz", Mexico City, Mexico.

Background: The method used to collect, store, and analyze data can affect the quality of data obtained. Many studies have shown the advantages of electronic systems over paper. Numerous tools are available for this purpose; however, they tend to be implemented only in high-budget protocols as they tend to be expensive.

Introduction: We report the experience of the Affective Disorders' Clinic of the National Institute of Psychiatry in Mexico City using Adobe Acrobat Forms combined with Dropbox as storage and distribution method for clinical protocols.

Materials And Methods: Adobe Acrobat 9 Pro was used to create personalized forms to capture data for seven different clinical purposes. Dropbox was used to share the distributed forms with fellow researchers. Completed forms were stored in Dropbox and the main researcher kept the data collection file, from where the forms were gathered for analysis.

Results: Sixteen forms created for different clinical purposes had an average of 1.2% missing fields.

Discussion: The main drawbacks relate to remote filling and the time spent in fine-tuning complex forms. The main advantages relate to the simplicity of the implementation of the method and the fact that no software other than the one available at the Institute is required.

Conclusions: Compared with other types of electronic data collection systems, the combination of these tools achieves similar goals and is low cost, requiring minimal knowledge of informatics.
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http://dx.doi.org/10.1089/tmj.2018.0029DOI Listing
March 2019