Hyejung Won

Hyejung Won

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Hyejung Won

Publications by authors named "Hyejung Won"

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Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Nat Genet 2019 Jul;51(7):1193

MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1038/s41588-019-0450-7DOI Listing
July 2019

Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility.

Nat Commun 2019 06 3;10(1):2396. Epub 2019 Jun 3.

Neurogenetics Program, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1038/s41467-019-10248-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546784PMC
June 2019

Identification of common genetic risk variants for autism spectrum disorder.

Nat Genet 2019 03 25;51(3):431-444. Epub 2019 Feb 25.

The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.

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http://dx.doi.org/10.1038/s41588-019-0344-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454898PMC
March 2019

The three-dimensional landscape of the genome in human brain tissue unveils regulatory mechanisms leading to schizophrenia risk.

Authors:
Won Mah Hyejung Won

Schizophr Res 2019 Mar 17. Epub 2019 Mar 17.

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA; UNC Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748876PMC
March 2019

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.

Nat Genet 2019 01 26;51(1):63-75. Epub 2018 Nov 26.

Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/articles/s41588-018-0269-7
Publisher Site
http://dx.doi.org/10.1038/s41588-018-0269-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481311PMC
January 2019

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Nat Genet 2018 03 26;50(3):381-389. Epub 2018 Feb 26.

MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1038/s41588-018-0059-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918692PMC
March 2018

The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis.

Cell 2018 01 4;172(1-2):289-304.e18. Epub 2018 Jan 4.

Neurogenetics Program, Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Center for Autism Research and Treatment, Semel Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924568PMC
January 2018

Widespread Allelic Heterogeneity in Complex Traits.

Am J Hum Genet 2017 May;100(5):789-802

Department of Computer Science, University of California, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420356PMC
May 2017

Chromosome conformation elucidates regulatory relationships in developing human brain.

Nature 2016 10 19;538(7626):523-527. Epub 2016 Oct 19.

Department of Neurology, Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/nature19847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358922PMC
October 2016

The road to precision psychiatry: translating genetics into disease mechanisms.

Nat Neurosci 2016 10;19(11):1397-1407

Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nn.4409DOI Listing
October 2016

Advancing the understanding of autism disease mechanisms through genetics.

Nat Med 2016 Apr;22(4):345-61

Neurogenetics Program, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072455PMC
http://dx.doi.org/10.1038/nm.4071DOI Listing
April 2016

The PsychENCODE project.

Nat Neurosci 2015 Dec;18(12):1707-12

Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675669PMC
December 2015

Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome.

Genome Med 2014 10;6(10):75. Epub 2014 Oct 10.

Neurogenetics Program, Department of Neurology, Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, CA 90095 USA ; Interdepartmental Ph.D. Program in Bioinformatics, University of California, Los Angeles, CA 90095 USA ; Department of Human Genetics, David Geffen Sch. of Medicine, UCLA, Los Angeles, CA USA.

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http://genomemedicine.biomedcentral.com/articles/10.1186/s13
Publisher Site
http://dx.doi.org/10.1186/s13073-014-0075-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213483PMC
October 2014

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism.

Cell 2013 Nov;155(5):1008-21

Program in Neurobehavioral Genetics, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Interdepartmental Program in Neuroscience, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.cell.2013.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934107PMC
November 2013

Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses.

Front Mol Neurosci 2013 5;6:19. Epub 2013 Aug 5.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology Daejeon, South Korea.

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http://dx.doi.org/10.3389/fnmol.2013.00019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733014PMC
August 2013

GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice.

Nat Med 2011 May 17;17(5):566-72. Epub 2011 Apr 17.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.

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http://dx.doi.org/10.1038/nm.2330DOI Listing
May 2011

Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53.

J Neurosci 2009 Feb;29(5):1586-95

National Creative Research Initiative Center for Synaptogenesis and Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1523/JNEUROSCI.4306-08.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6666077PMC
February 2009