Hwi Jin Ko

Hwi Jin Ko

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Hwi Jin Ko

Publications by authors named "Hwi Jin Ko"

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FET-based nanobiosensors for the detection of smell and taste.

Sci China Life Sci 2020 Jan 21. Epub 2020 Jan 21.

School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, 08826, Republic of Korea.

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http://dx.doi.org/10.1007/s11427-019-1571-8DOI Listing
January 2020

Preclinical Evaluation of UDCA-Containing Oral Formulation in Mice for the Treatment of Wet Age-Related Macular Degeneration.

Pharmaceutics 2019 Oct 29;11(11). Epub 2019 Oct 29.

T2B infrastructure center for ocular diseases, Inje University Busan Paik Hospital, 75 Bokjiro, Busanjin-gu, Busan 47392, Korea.

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http://dx.doi.org/10.3390/pharmaceutics11110561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920808PMC
October 2019

Bioelectronic Nose: An Emerging Tool for Odor Standardization.

Trends Biotechnol 2017 04 11;35(4):301-307. Epub 2017 Jan 11.

Interdisciplinary Program for Bioengineering, Seoul National University, Seoul 151-742, Republic of Korea; School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Republic of Korea; Advanced Institutes of Convergence Technology, Suwon 443-270, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2016.12.007DOI Listing
April 2017

A portable and multiplexed bioelectronic sensor using human olfactory and taste receptors.

Biosens Bioelectron 2017 Jan 17;87:901-907. Epub 2016 Sep 17.

Interdisciplinary Program for Bioengineering, Seoul National University, Seoul 151-742, Republic of Korea; School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Republic of Korea; Advanced Institutes of Convergence Technology, Suwon 443-270, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2016.09.040DOI Listing
January 2017

Bioelectronic Nose Using Odorant Binding Protein-Derived Peptide and Carbon Nanotube Field-Effect Transistor for the Assessment of Salmonella Contamination in Food.

Anal Chem 2016 12 15;88(23):11283-11287. Epub 2016 Nov 15.

Interdisciplinary Program for Bioengineering, Seoul National University , Seoul 151-742, Korea.

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http://dx.doi.org/10.1021/acs.analchem.6b03284DOI Listing
December 2016

Bioelectronic nose and its application to smell visualization.

J Biol Eng 2016 13;10:17. Epub 2016 Dec 13.

Bio-MAX Institute, Seoul, 151-742 Republic of Korea ; School of Chemical and Biological Engineering, Seoul National University, Seoul, 151-742 Republic of Korea ; Advanced Institutes of Convergence Technology, Suwon, Gyeonggido 443-270 Republic of Korea.

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http://dx.doi.org/10.1186/s13036-016-0041-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154139PMC
December 2016

Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.

FASEB J 2016 Mar 7;30(3):1328-38. Epub 2015 Dec 7.

*Program in Molecular Medicine, Diabetes Center of Excellence, and Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA; The Jackson Laboratory, Bar Harbor, Maine, USA; and World Class University Biomodulation Major, Department of Agricultural Biotechnology and Center for Food and Bioconvergence, Seoul National University, Seoul, Republic of Korea

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http://dx.doi.org/10.1096/fj.15-280610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750424PMC
March 2016

Real-time monitoring of geosmin and 2-methylisoborneol, representative odor compounds in water pollution using bioelectronic nose with human-like performance.

Biosens Bioelectron 2015 Dec 25;74:199-206. Epub 2015 Jun 25.

Interdisciplinary Program for Bioengineering, Seoul National University, Seoul 151-742, Republic of Korea; School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Republic of Korea; Advanced Institutes of Convergence Technology, Suwon 433-270, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2015.06.053DOI Listing
December 2015

Coupling of olfactory receptor and ion channel for rapid and sensitive visualization of odorant response.

Acta Biomater 2015 Aug 27;22:1-7. Epub 2015 Apr 27.

Interdisciplinary Program of Bioengineering, Seoul National University, Seoul 151-742, Republic of Korea; School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Republic of Korea; Bio-MAX Institute, Seoul National University, Seoul 151-742, Republic of Korea; Advanced Institutes of Convergence Technology, Suwon 443-270, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2015.04.034DOI Listing
August 2015

Deficiency of the tumor promoter gene wip1 induces insulin resistance.

Mol Endocrinol 2015 Jan;29(1):28-39

Department of Medicine (H.L.A., S.C., L.W., H.K.S.), Division of Endocrinology, Metabolism, and Diabetes (H.L.A., S.C., L.W., J.K.K., H.K.S.), and Program in Molecular Medicine (H.J.K., Y.L., D.Y.J., J.K.K.), University of Massachusetts Medical School, Worcester, Massachusetts 01605.

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http://dx.doi.org/10.1210/me.2014-1136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280527PMC
January 2015

Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood.

Adv Healthc Mater 2014 Mar 18;3(3):360-6. Epub 2013 Jul 18.

School of Chemical and Biological Engineering, Bio-MAX Institute, Seoul National University, Seoul, 151-742, Korea.

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http://dx.doi.org/10.1002/adhm.201300174DOI Listing
March 2014

Cell-based high-throughput odorant screening system through visualization on a microwell array.

Biosens Bioelectron 2014 Mar 25;53:18-25. Epub 2013 Sep 25.

Interdisciplinary Program of Bioengineering, Seoul, National University, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.bios.2013.09.039DOI Listing
March 2014

Glucose Tolerance in Mice is Linked to the Dose of the p53 Transactivation Domain.

Endocr Res 2013 Aug 26;38(3):139-150. Epub 2012 Oct 26.

a Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, University of Massachusetts Medical School , Worcester, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074905PMC
http://dx.doi.org/10.3109/07435800.2012.735735DOI Listing
August 2013

TRPM2 Ca2+ channel regulates energy balance and glucose metabolism.

Am J Physiol Endocrinol Metab 2012 Apr 24;302(7):E807-16. Epub 2012 Jan 24.

Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, USA.

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http://dx.doi.org/10.1152/ajpendo.00239.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330711PMC
April 2012

Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis.

Mol Cell Biol 2010 Dec 18;30(24):5787-94. Epub 2010 Oct 18.

Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://dx.doi.org/10.1128/MCB.00347-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004274PMC
December 2010

Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.

Diabetes 2010 Jun 23;59(6):1397-406. Epub 2010 Mar 23.

Department of Pharmacology, University of Virginia Health System, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.2337/db09-1061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874700PMC
June 2010

Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1.

Genes Dev 2010 Feb 15;24(3):256-64. Epub 2010 Jan 15.

Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

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http://dx.doi.org/10.1101/gad.1878510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811827PMC
February 2010

Specificity of odorant-binding proteins: a factor influencing the sensitivity of olfactory receptor-based biosensors.

Bioprocess Biosyst Eng 2010 Jan 2;33(1):55-62. Epub 2009 Jul 2.

School of Chemical and Biological Engineering, Seoul National University, Kwanak-Gu Shilim-Dong San 56-1, Seoul 151-744, Korea.

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http://dx.doi.org/10.1007/s00449-009-0348-3DOI Listing
January 2010

Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance.

Diabetes 2010 Jan 6;59(1):6-16. Epub 2009 Oct 6.

Department of Biochemistry and Molecular Biology, University of Southern California/Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California, USA.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db09-07
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http://dx.doi.org/10.2337/db09-0755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797945PMC
January 2010

Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance.

Mol Cell Biol 2010 Jan;30(1):106-15

Howard Hughes Medical Institute, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1128/MCB.01162-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798290PMC
January 2010

Prevention of steatosis by hepatic JNK1.

Cell Metab 2009 Dec;10(6):491-8

Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1016/j.cmet.2009.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804105PMC
December 2009

Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart.

Diabetes 2009 Nov 18;58(11):2536-46. Epub 2009 Aug 18.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.2337/db08-1361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768176PMC
November 2009

Real-time monitoring of odorant-induced cellular reactions using surface plasmon resonance.

Biosens Bioelectron 2009 Sep 10;25(1):55-60. Epub 2009 Jun 10.

School of Chemical and Biological Engineering, Institute of Bioengineering, Seoul National University, Gwanak-Gu, Sillim-Dong, San 56-1, Seoul, 151-744, Republic of Korea.

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http://dx.doi.org/10.1016/j.bios.2009.06.007DOI Listing
September 2009

Cell-based olfactory biosensor using microfabricated planar electrode.

Biosens Bioelectron 2009 Apr 2;24(8):2659-64. Epub 2009 Feb 2.

School of Chemical and Biological Engineering, Institute of Bioengineering, Seoul National University, Seoul 151-742, Republic of Korea.

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http://linkinghub.elsevier.com/retrieve/pii/S095656630900053
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http://dx.doi.org/10.1016/j.bios.2009.01.035DOI Listing
April 2009

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance.

Science 2008 Dec;322(5907):1539-43

Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1126/science.1160794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643026PMC
December 2008

Enhancement of odorant detection sensitivity by the expression of odorant-binding protein.

Biosens Bioelectron 2008 Feb 25;23(7):1017-23. Epub 2007 Oct 25.

School of Chemical and Biological Engineering, Institute of Bioengineering, Seoul National University, Gwanak-Gu, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.bios.2007.10.008DOI Listing
February 2008

Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.

Am J Physiol Endocrinol Metab 2007 Dec 2;293(6):E1687-96. Epub 2007 Oct 2.

Dept. of Cellular and Molecular Physiology, Penn State Univ. College of Medicine, 500 University Dr. (H166 C4600D, Hershey, PA 17033, USA.

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http://www.physiology.org/doi/10.1152/ajpendo.00256.2007
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http://dx.doi.org/10.1152/ajpendo.00256.2007DOI Listing
December 2007

Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B.

Mol Cell Biol 2007 Nov 27;27(21):7727-34. Epub 2007 Aug 27.

Cancer Biology Program, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1128/MCB.00959-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169063PMC
November 2007

Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes.

Am J Physiol Endocrinol Metab 2007 Jul;293(1):E327-36

Department of Internal Medicine, Section of Endocrinology and Metabolism, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1152/ajpendo.00376.2006DOI Listing
July 2007

Functional analysis of olfactory receptors expressed in a HEK-293 cell system by using cameleons.

J Microbiol Biotechnol 2007 Jun;17(6):928-33

School of Chemical and Biological Engineering, Seoul National University, Seoul 151-744, Korea.

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June 2007

Piezoelectric biosensor using olfactory receptor protein expressed in Escherichia coli.

Biosens Bioelectron 2006 Apr 16;21(10):1981-6. Epub 2005 Nov 16.

School of Chemical and Biological Engineering, Seoul National University, Gwanak-Gu Sillim-Dong San 56-1, Seoul 151-744, Republic of Korea.

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http://dx.doi.org/10.1016/j.bios.2005.10.002DOI Listing
April 2006

Dual signal transduction mediated by a single type of olfactory receptor expressed in a heterologous system.

Biol Chem 2006 Jan;387(1):59-68

School of Chemical and Biological Engineering, Seoul National University, Gwanak-Gu Sillim-Dong San 56-1, Seoul 151-744, Korea.

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https://www.degruyter.com/view/j/bchm.2006.387.issue-1/bc.20
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http://dx.doi.org/10.1515/BC.2006.009DOI Listing
January 2006

Piezoelectric olfactory biosensor: ligand specificity and dose-dependence of an olfactory receptor expressed in a heterologous cell system.

Biosens Bioelectron 2005 Jan;20(7):1327-32

School of Chemical Engineering and Institute of Chemical Processes, Seoul National University, Kwanak-Gu Shilim-Dong San 56-1, Seoul 151-744, South Korea.

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http://linkinghub.elsevier.com/retrieve/pii/S095656630400234
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http://dx.doi.org/10.1016/j.bios.2004.05.002DOI Listing
January 2005