Publications by authors named "Humaira Ayub"

16Publications

MicroRNA biogenesis, gene silencing mechanisms and role in breast, ovarian and prostate cancer.

Authors:
Sanna Khan Humaira Ayub Taous Khan Fazli Wahid

Biochimie 2019 Dec 4;167:12-24. Epub 2019 Sep 4.

Department of Biotechnology, COMSATS University Islamabad, Abbottabad Campus, 22060, Pakistan. Electronic address:

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December 2019

Molecular Mechanisms of Complement System Proteins and Matrix Metalloproteinases in the Pathogenesis of Age-Related Macular Degeneration.

Authors:
Naima Mansoor Fazli Wahid Maleeha Azam Khadim Shah Anneke I den Hollander Raheel Qamar Humaira Ayub

Curr Mol Med 2019 ;19(10):705-718

Department of Biotechnology, COMSATS University Islamabad, Abbottabad Campus, 22060, Pakistan.

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January 2019

The protective variant rs7173049 at LOXL1 locus impacts on retinoic acid signaling pathway in pseudoexfoliation syndrome.

Authors:
Daniel Berner Ursula Hoja Matthias Zenkel James Julian Ross Steffen Uebe Daniela Paoli Paolo Frezzotti Robyn M Rautenbach Ari Ziskind Susan E Williams Trevor R Carmichael Michele Ramsay Fotis Topouzis Anthi Chatzikyriakidou Alexandros Lambropoulos Periasamy Sundaresan Humaira Ayub Farah Akhtar Raheel Qamar Juan C Zenteno Marisa Cruz-Aguilar Yury S Astakhov Michael Dubina Janey Wiggs Mineo Ozaki Friedrich E Kruse Tin Aung André Reis Chiea Chuen Khor Francesca Pasutto Ursula Schlötzer-Schrehardt

Hum Mol Genet 2019 Aug;28(15):2531-2548

Department of Ophthalmology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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August 2019

Association of rs10490924 in ARMS2/HTRA1 with age-related macular degeneration in the Pakistani population.

Authors:
Humaira Ayub Sobia Shafique Aisha Azam Irfan Muslim Nauman A Qazi Farah Akhtar Muhammad Asim Khan Adil Ayub Shaheena Bashir Bjorn Bakker Shakil Ahmed Maleeha Azam Anneke I den Hollander Raheel Qamar

Ann Hum Genet 2019 07 20;83(4):285-290. Epub 2019 Mar 20.

Transalational Genomics Laboratory, Department of Biosciences, COMSATS University Islamabad, Pakistan.

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July 2019

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

Authors:
Tin Aung Mineo Ozaki Mei Chin Lee Ursula Schlötzer-Schrehardt Gudmar Thorleifsson Takanori Mizoguchi Robert P Igo Aravind Haripriya Susan E Williams Yury S Astakhov Andrew C Orr Kathryn P Burdon Satoko Nakano Kazuhiko Mori Khaled Abu-Amero Michael Hauser Zheng Li Gopalakrishnan Prakadeeswari Jessica N Cooke Bailey Alina Popa Cherecheanu Jae H Kang Sarah Nelson Ken Hayashi Shin-Ichi Manabe Shigeyasu Kazama Tomasz Zarnowski Kenji Inoue Murat Irkec Miguel Coca-Prados Kazuhisa Sugiyama Irma Järvelä Patricio Schlottmann S Fabian Lerner Hasnaa Lamari Yildirim Nilgün Mukharram Bikbov Ki Ho Park Soon Cheol Cha Kenji Yamashiro Juan C Zenteno Jost B Jonas Rajesh S Kumar Shamira A Perera Anita S Y Chan Nino Kobakhidze Ronnie George Lingam Vijaya Tan Do Deepak P Edward Lourdes de Juan Marcos Mohammad Pakravan Sasan Moghimi Ryuichi Ideta Daniella Bach-Holm Per Kappelgaard Barbara Wirostko Samuel Thomas Daniel Gaston Karen Bedard Wenda L Greer Zhenglin Yang Xueyi Chen Lulin Huang Jinghong Sang Hongyan Jia Liyun Jia Chunyan Qiao Hui Zhang Xuyang Liu Bowen Zhao Ya-Xing Wang Liang Xu Stéphanie Leruez Pascal Reynier George Chichua Sergo Tabagari Steffen Uebe Matthias Zenkel Daniel Berner Georg Mossböck Nicole Weisschuh Ursula Hoja Ulrich-Christoph Welge-Luessen Christian Mardin Panayiota Founti Anthi Chatzikyriakidou Theofanis Pappas Eleftherios Anastasopoulos Alexandros Lambropoulos Arkasubhra Ghosh Rohit Shetty Natalia Porporato Vijayan Saravanan Rengaraj Venkatesh Chandrashekaran Shivkumar Narendran Kalpana Sripriya Sarangapani Mozhgan R Kanavi Afsaneh Naderi Beni Shahin Yazdani Alireza Lashay Homa Naderifar Nassim Khatibi Antonio Fea Carlo Lavia Laura Dallorto Teresa Rolle Paolo Frezzotti Daniela Paoli Erika Salvi Paolo Manunta Yosai Mori Kazunori Miyata Tomomi Higashide Etsuo Chihara Satoshi Ishiko Akitoshi Yoshida Masahide Yanagi Yoshiaki Kiuchi Tsutomu Ohashi Toshiya Sakurai Takako Sugimoto Hideki Chuman Makoto Aihara Masaru Inatani Masahiro Miyake Norimoto Gotoh Fumihiko Matsuda Nagahisa Yoshimura Yoko Ikeda Morio Ueno Chie Sotozono Jin Wook Jeoung Min Sagong Kyu Hyung Park Jeeyun Ahn Marisa Cruz-Aguilar Sidi M Ezzouhairi Abderrahman Rafei Yaan Fun Chong Xiao Yu Ng Shuang Ru Goh Yueming Chen Victor H K Yong Muhammad Imran Khan Olusola O Olawoye Adeyinka O Ashaye Idakwo Ugbede Adeola Onakoya Nkiru Kizor-Akaraiwe Chaiwat Teekhasaenee Yanin Suwan Wasu Supakontanasan Suhanya Okeke Nkechi J Uche Ifeoma Asimadu Humaira Ayub Farah Akhtar Ewa Kosior-Jarecka Urszula Lukasik Ignacio Lischinsky Vania Castro Rodolfo Perez Grossmann Gordana Sunaric Megevand Sylvain Roy Edward Dervan Eoin Silke Aparna Rao Priti Sahay Pablo Fornero Osvaldo Cuello Delia Sivori Tamara Zompa Richard A Mills Emmanuelle Souzeau Paul Mitchell Jie Jin Wang Alex W Hewitt Michael Coote Jonathan G Crowston Sergei Y Astakhov Eugeny L Akopov Anton Emelyanov Vera Vysochinskaya Gyulli Kazakbaeva Rinat Fayzrakhmanov Saleh A Al-Obeidan Ohoud Owaidhah Leyla Ali Aljasim Balram Chowbay Jia Nee Foo Raphael Q Soh Kar Seng Sim Zhicheng Xie Augustine W O Cheong Shi Qi Mok Hui Meng Soo Xiao Yin Chen Su Qin Peh Khai Koon Heng Rahat Husain Su-Ling Ho Axel M Hillmer Ching-Yu Cheng Francisco A Escudero-Domínguez Rogelio González-Sarmiento Frederico Martinon-Torres Antonio Salas Kessara Pathanapitoon Linda Hansapinyo Boonsong Wanichwecharugruang Naris Kitnarong Anavaj Sakuntabhai Hip X Nguyn Giang T T Nguyn Trình V Nguyn Werner Zenz Alexander Binder Daniela S Klobassa Martin L Hibberd Sonia Davila Stefan Herms Markus M Nöthen Susanne Moebus Robyn M Rautenbach Ari Ziskind Trevor R Carmichael Michele Ramsay Lydia Álvarez Montserrat García Héctor González-Iglesias Pedro P Rodríguez-Calvo Luis Fernández-Vega Cueto Çilingir Oguz Nevbahar Tamcelik Eray Atalay Bilge Batu Dilek Aktas Burcu Kasım M Roy Wilson Anne L Coleman Yutao Liu Pratap Challa Leon Herndon Rachel W Kuchtey John Kuchtey Karen Curtin Craig J Chaya Alan Crandall Linda M Zangwill Tien Yin Wong Masakazu Nakano Shigeru Kinoshita Anneke I den Hollander Eija Vesti John H Fingert Richard K Lee Arthur J Sit Bradford J Shingleton Ningli Wang Daniele Cusi Raheel Qamar Peter Kraft Margaret A Pericak-Vance Soumya Raychaudhuri Steffen Heegaard Tero Kivelä André Reis Friedrich E Kruse Robert N Weinreb Louis R Pasquale Jonathan L Haines Unnur Thorsteinsdottir Fridbert Jonasson R Rand Allingham Dan Milea Robert Ritch Toshiaki Kubota Kei Tashiro Eranga N Vithana Shazia Micheal Fotis Topouzis Jamie E Craig Michael Dubina Periasamy Sundaresan Kari Stefansson Janey L Wiggs Francesca Pasutto Chiea Chuen Khor

Nat Genet 2017 07 29;49(7):993-1004. Epub 2017 May 29.

Singapore Eye Research Institute, Singapore.

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July 2017

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.

Authors:
Chiea Chuen Khor Tan Do Hongyan Jia Masakazu Nakano Ronnie George Khaled Abu-Amero Roopam Duvesh Li Jia Chen Zheng Li Monisha E Nongpiur Shamira A Perera Chunyan Qiao Hon-Tym Wong Hiroshi Sakai Mônica Barbosa de Melo Mei-Chin Lee Anita S Chan Yaakub Azhany Thi Lam Huong Dao Yoko Ikeda Rodolfo A Perez-Grossmann Tomasz Zarnowski Alexander C Day Jost B Jonas Pancy O S Tam Tuan Anh Tran Humaira Ayub Farah Akhtar Shazia Micheal Paul T K Chew Leyla A Aljasim Tanuj Dada Tam Thi Luu Mona S Awadalla Naris Kitnarong Boonsong Wanichwecharungruang Yee Yee Aung Jelinar Mohamed-Noor Saravanan Vijayan Sripriya Sarangapani Rahat Husain Aliza Jap Mani Baskaran David Goh Daniel H Su Huaizhou Wang Vernon K Yong Leonard W Yip Tuyet Bach Trinh Manchima Makornwattana Thanh Thu Nguyen Edgar U Leuenberger Ki-Ho Park Widya Artini Wiyogo Rajesh S Kumar Celso Tello Yasuo Kurimoto Suman S Thapa Kessara Pathanapitoon John F Salmon Yong Ho Sohn Antonio Fea Mineo Ozaki Jimmy S M Lai Visanee Tantisevi Chaw Chaw Khaing Takanori Mizoguchi Satoko Nakano Chan-Yun Kim Guangxian Tang Sujie Fan Renyi Wu Hailin Meng Thi Thuy Giang Nguyen Tien Dat Tran Morio Ueno Jose Maria Martinez Norlina Ramli Yin Mon Aung Rigo Daniel Reyes Stephen A Vernon Seng Kheong Fang Zhicheng Xie Xiao Yin Chen Jia Nee Foo Kar Seng Sim Tina T Wong Desmond T Quek Rengaraj Venkatesh Srinivasan Kavitha Subbiah R Krishnadas Nagaswamy Soumittra Balekudaru Shantha Boon-Ang Lim Jeanne Ogle José P C de Vasconcellos Vital P Costa Ricardo Y Abe Bruno B de Souza Chelvin C Sng Maria C Aquino Ewa Kosior-Jarecka Guillermo Barreto Fong Vania Castro Tamanaja Ricardo Fujita Yuzhen Jiang Naushin Waseem Sancy Low Huan Nguyen Pham Sami Al-Shahwan E Randy Craven Muhammad Imran Khan Rrima Dada Kuldeep Mohanty Muneeb A Faiq Alex W Hewitt Kathryn P Burdon Eng Hui Gan Anuwat Prutthipongsit Thipnapa Patthanathamrongkasem Mary Ann T Catacutan Irene R Felarca Chona S Liao Emma Rusmayani Vira Wardhana Istiantoro Giulia Consolandi Giulia Pignata Carlo Lavia Prin Rojanapongpun Lerprat Mangkornkanokpong Sunee Chansangpetch Jonathan C H Chan Bonnie N K Choy Jennifer W H Shum Hlaing May Than Khin Thida Oo Aye Thi Han Victor H Yong Xiao-Yu Ng Shuang Ru Goh Yaan Fun Chong Martin L Hibberd Mark Seielstad Eileen Png Sarah J Dunstan Nguyen Van Vinh Chau Jinxin Bei Yi Xin Zeng Abhilasha Karkey Buddha Basnyat Francesca Pasutto Daniela Paoli Paolo Frezzotti Jie Jin Wang Paul Mitchell John H Fingert R Rand Allingham Michael A Hauser Soon Thye Lim Soo Hong Chew Richard P Ebstein Anavaj Sakuntabhai Kyu Hyung Park Jeeyun Ahn Greet Boland Harm Snippe Richard Stead Raquel Quino Su Nyunt Zaw Urszula Lukasik Rohit Shetty Mimiwati Zahari Hyoung Won Bae Nay Lin Oo Toshiaki Kubota Anita Manassakorn Wing Lau Ho Laura Dallorto Young Hoon Hwang Christine A Kiire Masako Kuroda Zeiras Eka Djamal Jovell Ian M Peregrino Arkasubhra Ghosh Jin Wook Jeoung Tung S Hoan Nuttamon Srisamran Thayanithi Sandragasu Saw Htoo Set Vi Huyen Doan Shomi S Bhattacharya Ching-Lin Ho Donald T Tan Ramanjit Sihota Seng-Chee Loon Kazuhiko Mori Shigeru Kinoshita Anneke I den Hollander Raheel Qamar Ya-Xing Wang Yik Y Teo E-Shyong Tai Curt Hartleben-Matkin David Lozano-Giral Seang Mei Saw Ching-Yu Cheng Juan C Zenteno Chi Pui Pang Huong T T Bui Owen Hee Jamie E Craig Deepak P Edward Michiko Yonahara Jamil Miguel Neto Maria L Guevara-Fujita Liang Xu Robert Ritch Ahmad Tajudin Liza-Sharmini Tien Y Wong Saleh Al-Obeidan Nhu Hon Do Periasamy Sundaresan Clement C Tham Paul J Foster Lingam Vijaya Kei Tashiro Eranga N Vithana Ningli Wang Tin Aung

Nat Genet 2016 May 4;48(5):556-62. Epub 2016 Apr 4.

Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.

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May 2016

Variants in the ASB10 Gene Are Associated with Primary Open Angle Glaucoma.

Authors:
Shazia Micheal Humaira Ayub Farrah Islam Sorath Noorani Siddiqui Wajid Ali Khan Farah Akhtar Raheel Qamar Muhammad Imran Khan Anneke I den Hollander

PLoS One 2015 29;10(12):e0145005. Epub 2015 Dec 29.

Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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June 2016

Homozygosity mapping and targeted sanger sequencing reveal genetic defects underlying inherited retinal disease in families from pakistan.

Authors:
Maleeha Maria Muhammad Ajmal Maleeha Azam Nadia Khalida Waheed Sorath Noorani Siddiqui Bilal Mustafa Humaira Ayub Liaqat Ali Shakeel Ahmad Shazia Micheal Alamdar Hussain Syed Tahir Abbas Shah Syeda Hafiza Benish Ali Waqas Ahmed Yar Muhammad Khan Anneke I den Hollander Lonneke Haer-Wigman Rob W J Collin Muhammad Imran Khan Raheel Qamar Frans P M Cremers

PLoS One 2015 16;10(3):e0119806. Epub 2015 Mar 16.

Department of Biosciences, Commission on Science and Technology for Sustainable Development in the South Institute of Information Technology, Islamabad, Pakistan; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands; Radboud Institute for Molecular Life sciences, Radboud University Nijmegen, Nijmegen, the Netherlands.

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January 2016

Association of known common genetic variants with primary open angle, primary angle closure, and pseudoexfoliation glaucoma in Pakistani cohorts.

Authors:
Shazia Micheal Humaira Ayub Muhammad Imran Khan Bjorn Bakker Frederieke E Schoenmaker-Koller Mahmood Ali Farah Akhtar Wajid Ali Khan Raheel Qamar Anneke I den Hollander

Mol Vis 2014 4;20:1471-9. Epub 2014 Nov 4.

Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, the Netherlands ; Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.

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June 2015

Exome sequencing identifies three novel candidate genes implicated in intellectual disability.

Authors:
Zehra Agha Zafar Iqbal Maleeha Azam Humaira Ayub Lisenka E L M Vissers Christian Gilissen Syeda Hafiza Benish Ali Moeen Riaz Joris A Veltman Rolph Pfundt Hans van Bokhoven Raheel Qamar

PLoS One 2014 18;9(11):e112687. Epub 2014 Nov 18.

Department of Biosciences, Faculty of Science, COMSATS Institute of Information Technology, Islamabad, Pakistan; Department of Biochemistry, Al-Nafees Medical College & Hospital, Isra University, Islamabad, Pakistan.

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July 2015

Association of a polymorphism in the BIRC6 gene with pseudoexfoliative glaucoma.

Authors:
Humaira Ayub Shazia Micheal Farah Akhtar Muhammad Imran Khan Shaheena Bashir Nadia K Waheed Mahmood Ali Frederieke E Schoenmaker-Koller Sobia Shafique Raheel Qamar Anneke I den Hollander

PLoS One 2014 13;9(8):e105023. Epub 2014 Aug 13.

Department of Ophthalmology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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December 2015

Identification of novel CYP1B1 gene mutations in patients with primary congenital and primary open-angle glaucoma.

Authors:
Shazia Micheal Humaira Ayub Saemah N Zafar Bjorn Bakker Mahmood Ali Farah Akhtar Farrah Islam Muhammad I Khan Raheel Qamar Anneke I den Hollander

Clin Exp Ophthalmol 2015 Jan-Feb;43(1):31-9. Epub 2014 Sep 23.

Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, The Netherlands.

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July 2015

Genetic spectrum of autosomal recessive non-syndromic hearing loss in Pakistani families.

Authors:
Sobia Shafique Saima Siddiqi Margit Schraders Jaap Oostrik Humaira Ayub Ammad Bilal Muhammad Ajmal Celia Zazo Seco Tim M Strom Atika Mansoor Kehkashan Mazhar Syed Tahir A Shah Alamdar Hussain Maleeha Azam Hannie Kremer Raheel Qamar

PLoS One 2014 20;9(6):e100146. Epub 2014 Jun 20.

COMSATS Institute of Information Technology, Park Road, Islamabad, Pakistan; Al-Nafees Medical College & Hospital, Isra University, Islamabad, Pakistan.

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February 2015

Exome sequencing identifies a novel and a recurrent BBS1 mutation in Pakistani families with Bardet-Biedl syndrome.

Authors:
Muhammad Ajmal Muhammad Imran Khan Kornelia Neveling Ali Tayyab Sulman Jaffar Ahmed Sadeque Humaira Ayub Nasir Mahmood Abbasi Moeen Riaz Shazia Micheal Christian Gilissen Syeda Hafiza Benish Ali Maleeha Azam Rob W J Collin Frans P M Cremers Raheel Qamar

Mol Vis 2013 21;19:644-53. Epub 2013 Mar 21.

Department of Biosciences, Faculty of Science, COMSATS Institute of Information Technology, Islamabad, Pakistan.

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September 2013

The genetic spectrum of familial hypercholesterolemia in Pakistan.

Authors:
Waqas Ahmed Ros Whittall Moeen Riaz Muhammad Ajmal Ahmed Sadeque Humaira Ayub Raheel Qamar Steve E Humphries

Clin Chim Acta 2013 Jun 25;421:219-25. Epub 2013 Mar 25.

COMSATS Institute of Information Technology, Islamabad, Pakistan.

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June 2013

Association of eNOS and HSP70 gene polymorphisms with glaucoma in Pakistani cohorts.

Authors:
Humaira Ayub Muhammad Imran Khan Shazia Micheal Farah Akhtar Muhammad Ajmal Sobia Shafique Syeda Hafiza Benish Ali Anneke I den Hollander Asifa Ahmed Raheel Qamar

Mol Vis 2010 Jan 11;16:18-25. Epub 2010 Jan 11.

Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan.

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January 2010