Publications by authors named "Hugues de Thé"

147Publications

JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML.

Authors:
Tracy Dagher Nabih Maslah Valérie Edmond Bruno Cassinat William Vainchenker Stéphane Giraudier Florence Pasquier Emmanuelle Verger Michiko Niwa-Kawakita Valérie Lallemand-Breitenbach Isabelle Plo Jean-Jacques Kiladjian Jean-Luc Villeval Hugues de Thé

J Exp Med 2021 Feb;218(2)

INSERM U944, Centre National de la Recherche Scientifique (CNRS) UMR7212, IRSL, Hôpital Saint-Louis, Paris, France.

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February 2021

Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway.

Authors:
Ruimeng Yang Ming Zhan Miaomiao Guo Hao Yuan Yiqin Wang Yiyue Zhang Wenqing Zhang Saijuan Chen Hugues de The Zhu Chen Jun Zhou Jun Zhu

Cell Death Differ 2021 Jan 24;28(1):170-183. Epub 2020 Jul 24.

CNRS-LIA Hematology and Cancer, Sino-French Research Center for Life Sciences and Genomics, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, PR China.

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January 2021

Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress.

Authors:
Juliette Humeau Allan Sauvat Giulia Cerrato Wei Xie Friedemann Loos Francesca Iannantuoni Lucillia Bezu Sarah Lévesque Juliette Paillet Jonathan Pol Marion Leduc Laurence Zitvogel Hugues de Thé Oliver Kepp Guido Kroemer

EMBO Mol Med 2020 05 23;12(5):e11622. Epub 2020 Apr 23.

Equipe labellisée par la Ligue contre le Cancer, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Université de Paris, Paris, France.

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May 2020

Classic and Variants APLs, as Viewed from a Therapy Response.

Authors:
Marie-Claude Geoffroy Hugues de Thé

Cancers (Basel) 2020 Apr 14;12(4). Epub 2020 Apr 14.

Institut National de la Santé et de la Recherche Médicale (INSERM) U944, Equipe Labellisée par la Ligue Nationale contre le Cancer, 75010 Paris, France.

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April 2020

Arsenic trioxide (AsO) as a maintenance therapy for adult T cell leukemia/lymphoma.

Authors:
Ambroise Marçais Lucy Cook Aviva Witkover Vahid Asnafi Véronique Avettand-Fenoel Richard Delarue Morgane Cheminant David Sibon Laurent Frenzel Hugues de Thé Charles R M Bangham Ali Bazarbachi Olivier Hermine Felipe Suarez

Retrovirology 2020 03 21;17(1). Epub 2020 Mar 21.

Service d'Hématologie Adultes, Institut Imagine, Hôpital Universitaire Necker Enfants Malades, APHP, Université de Paris, 149-161 rue de Sèvres, 75743, Paris Cedex 15, France.

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March 2020

A molecule inducing androgen receptor degradation and selectively targeting prostate cancer cells.

Authors:
Serge Auvin Harun Öztürk Yusuf T Abaci Gisele Mautino Florence Meyer-Losic Florence Jollivet Tarig Bashir Hugues de Thé Umut Sahin

Life Sci Alliance 2019 08 20;2(4). Epub 2019 Aug 20.

Université de Paris, Hôpital St. Louis, Paris, France

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August 2019

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia.

Authors:
Mark D McKenzie Margherita Ghisi Ethan P Oxley Steven Ngo Luisa Cimmino Cécile Esnault Ruijie Liu Jessica M Salmon Charles C Bell Nouraiz Ahmed Michael Erlichster Matthew T Witkowski Grace J Liu Michael Chopin Aleksandar Dakic Emilia Simankowicz Giovanna Pomilio Tina Vu Pavle Krsmanovic Shian Su Luyi Tian Tracey M Baldwin Daniela A Zalcenstein Ladina DiRago Shu Wang Donald Metcalf Ricky W Johnstone Ben A Croker Graeme I Lancaster Andrew J Murphy Shalin H Naik Stephen L Nutt Vitek Pospisil Timm Schroeder Meaghan Wall Mark A Dawson Andrew H Wei Hugues de Thé Matthew E Ritchie Johannes Zuber Ross A Dickins

Cell Stem Cell 2019 08;25(2):258-272.e9

Australian Centre for Blood Diseases, Monash University, Commercial Road, Melbourne, VIC 3004, Australia. Electronic address:

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August 2019

Primitive macrophages are dispensable for HSPC mobilization and definitive hematopoiesis.

Authors:
Hao Yuan Shuo Gao Huiqiao Chen Xiaohui Liu Jun Zhou Hugues de The Jun Zhu

Blood 2019 08 16;134(9):782-784. Epub 2019 Jul 16.

Centre National de la Recherche Scientifique-Laboratoire International Associé (CNRS-LIA) Hematology and Cancer, Sino-French Research Center for Life Sciences and Genomics, State Key Laboratory of Medical Genomics, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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August 2019

Interferon regulatory factor 2 binding protein 2b regulates neutrophil macrophage fate during zebrafish definitive myelopoiesis.

Authors:
Luxiang Wang Shuo Gao Haihong Wang Chang Xue Xiaohui Liu Hao Yuan Zixuan Wang Saijuan Chen Zhu Chen Hugues de Thé Yiyue Zhang Wenqing Zhang Jun Zhu Jun Zhou

Haematologica 2020 31;105(2):325-337. Epub 2020 Jan 31.

CNRS-LIA Hematology and Cancer, Sino-French Research Center for Life Sciences and Genomics, State Key Laboratory of Medical Genomics, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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January 2020

TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy.

Authors:
Rui Meng Yang Jiong Tao Ming Zhan Hao Yuan Hai Hong Wang Sai Juan Chen Zhu Chen Hugues de Thé Jun Zhou Ying Guo Jun Zhu

Cell Death Differ 2019 Nov 1;26(11):2430-2446. Epub 2019 Mar 1.

CNRS-LIA Hematology and Cancer, Sino-French Research Center for Life Sciences and Genomics, State Key Laboratory of Medical Genomics, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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November 2019

-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias.

Authors:
Cécile Esnault Ramy Rahmé Kim L Rice Caroline Berthier Coline Gaillard Samuel Quentin Anne-Lise Maubert Scott Kogan Hugues de Thé

Blood 2019 03 23;133(13):1495-1506. Epub 2019 Jan 23.

INSERM U944, Equipe Labellisée par la Ligue Nationale contre le Cancer, Paris, France.

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March 2019

Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia.

Authors:
Coline Gaillard Sangeetha Surianarayanan Trevor Bentley Matthew R Warr Briana Fitch Huimin Geng Emmanuelle Passegué Hugues de Thé Scott C Kogan

Blood Adv 2018 10;2(19):2462-2466

Department of Laboratory Medicine and Helen Diller Family Comprehensive Cancer Center and.

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October 2018

Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation.

Authors:
Stéphanie Gachet Tiama El-Chaar David Avran Eulalia Genesca Frédéric Catez Samuel Quentin Marc Delord Gabriel Thérizols Delphine Briot Godelieve Meunier Lucie Hernandez Marika Pla Willem K Smits Jessica G Buijs-Gladdines Wouter Van Loocke Gerben Menschaert Isabelle André-Schmutz Tom Taghon Pieter Van Vlierberghe Jules P Meijerink André Baruchel Hervé Dombret Emmanuelle Clappier Jean-Jacques Diaz Claude Gazin Hugues de Thé François Sigaux Jean Soulier

Cancer Discov 2018 12 28;8(12):1614-1631. Epub 2018 Sep 28.

INSERM UMR944 and CNRS UMR7212, Hôpital Saint-Louis, Paris, France.

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December 2018

PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers.

Authors:
Géraldine Gentric Yann Kieffer Virginie Mieulet Oumou Goundiam Claire Bonneau Fariba Nemati Ilse Hurbain Graca Raposo Tatiana Popova Marc-Henri Stern Valérie Lallemand-Breitenbach Sebastian Müller Tatiana Cañeque Raphaël Rodriguez Anne Vincent-Salomon Hugues de Thé Rodrigue Rossignol Fatima Mechta-Grigoriou

Cell Metab 2019 01 20;29(1):156-173.e10. Epub 2018 Sep 20.

Institut Curie, Stress and Cancer Laboratory, Equipe Labelisée par la Ligue Nationale contre le Cancer, PSL Research University, 26, rue d'Ulm, 75005 Paris, France; Inserm, U830, 26, rue d'Ulm, Paris 75005, France. Electronic address:

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January 2019

Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia.

Authors:
Jacqueline Lehmann-Che Cécile Bally Eric Letouzé Caroline Berthier Hao Yuan Florence Jollivet Lionel Ades Bruno Cassinat Pierre Hirsch Arnaud Pigneux Marie-Joelle Mozziconacci Scott Kogan Pierre Fenaux Hugues de Thé

Nat Commun 2018 05 24;9(1):2047. Epub 2018 May 24.

INSERM U944, Equipe Labellisée par la Ligue Nationale contre le Cancer, Institut Universitaire d'Hématologie (IUH), 75010, Paris, France.

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May 2018

Publisher Correction: RING tetramerization is required for nuclear body biogenesis and PML sumoylation.

Authors:
Pengran Wang Shirine Benhenda Haiyan Wu Valérie Lallemand-Breitenbach Tao Zhen Florence Jollivet Laurent Peres Yuwen Li Sai-Juan Chen Zhu Chen Hugues de Thé Guoyu Meng

Nat Commun 2018 05 4;9(1):1841. Epub 2018 May 4.

State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, China.

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May 2018

PML nuclear bodies: from architecture to function.

Authors:
Valérie Lallemand-Breitenbach Hugues de Thé

Curr Opin Cell Biol 2018 06 30;52:154-161. Epub 2018 Apr 30.

INSERM U944-CNRS UMR 7212, Equipe labellisée par la Ligue Nationale contre le Cancer, France; Université Paris Diderot, Sorbonne Paris Cité, Hôpital St. Louis, 1 Avenue Claude Vellefaux, 75475 Paris cedex 10, France; Collège de France, PSL Research University, 11 Place Marcelin Berthelot, 75231 Paris Cedex 05, France; Service de Biochimie, Hôpital St. Louis, AP-HP, Paris, France.

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June 2018

RNF4 regulates zebrafish granulopoiesis through the DNMT1-C/EBPα axis.

Authors:
Luxiang Wang Xiaohui Liu Haihong Wang Hao Yuan Saijuan Chen Zhu Chen Hugues de The Jun Zhou Jun Zhu

FASEB J 2018 09 10;32(9):4930-4940. Epub 2018 Apr 10.

CNRS-LIA Hematology and Cancer, Sino-French Research Center for Life Sciences and Genomics, State Key Laboratory of Medical Genomics, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; and.

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September 2018

RING tetramerization is required for nuclear body biogenesis and PML sumoylation.

Authors:
Pengran Wang Shirine Benhenda Haiyan Wu Valérie Lallemand-Breitenbach Tao Zhen Florence Jollivet Laurent Peres Yuwen Li Sai-Juan Chen Zhu Chen Hugues de Thé Guoyu Meng

Nat Commun 2018 03 29;9(1):1277. Epub 2018 Mar 29.

State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, China.

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March 2018

Stability of HTLV-2 antisense protein is controlled by PML nuclear bodies in a SUMO-dependent manner.

Authors:
Louise Dubuisson Florence Lormières Stefania Fochi Jocelyn Turpin Amandine Pasquier Estelle Douceron Anaïs Oliva Ali Bazarbachi Valérie Lallemand-Breitenbach Hugues De Thé Chloé Journo Renaud Mahieux

Oncogene 2018 05 6;37(21):2806-2816. Epub 2018 Mar 6.

International Center for Research in Infectiology, Retroviral Oncogenesis Laboratory, INSERM U1111 - Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Lyon, F-69007, Lyon, France.

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May 2018