Hugo R Rosen

Hugo R Rosen

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Hugo R Rosen

Publications by authors named "Hugo R Rosen"

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Diet associations with nonalcoholic fatty liver disease in an ethnically diverse population: the Multiethnic Cohort.

Hepatology 2019 Sep 25. Epub 2019 Sep 25.

Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1002/hep.30967DOI Listing
September 2019

Chronic Liver Disease in Humans Causes Expansion and Differentiation of Liver Lymphatic Endothelial Cells.

Front Immunol 2019 15;10:1036. Epub 2019 May 15.

Division of Gastroenterology and Hepatology, Department of Medicine, School of Medicine, University of Colorado, Aurora, CO, United States.

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http://dx.doi.org/10.3389/fimmu.2019.01036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530422PMC
May 2019

Functional Microbiomics in Liver Transplantation: Identifying Novel Targets for Improving Allograft Outcomes.

Transplantation 2019 04;103(4):668-678

GI and Liver Innate Immune Program, University of Colorado School of Medicine, Aurora, CO.

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http://dx.doi.org/10.1097/TP.0000000000002568DOI Listing
April 2019

Revisiting the Paradox of Interferon-Stimulated Gene Expression as a Predictor of Hepatitis C Virus Treatment Response, a Decade Later.

Hepatology 2018 12 13;68(6):2053-2055. Epub 2018 Nov 13.

Division of Gastroenterology & Hepatology, Department of Medicine, USC Research Center for Liver Diseases, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1002/hep.30195DOI Listing
December 2018

Early and late changes in natural killer cells in response to ledipasvir/sofosbuvir treatment.

Hepatol Commun 2018 04 1;2(4):364-375. Epub 2018 Mar 1.

Division of Gastroenterology and Hepatology University of Colorado Denver Aurora CO.

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http://dx.doi.org/10.1002/hep4.1166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880201PMC
April 2018

Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection.

Hepatology 2018 01 15;67(1):71-85. Epub 2017 Nov 15.

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA.

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http://dx.doi.org/10.1002/hep.29409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739980PMC
January 2018

Hepatic Complications of Anorexia Nervosa.

Dig Dis Sci 2017 11 20;62(11):2977-2981. Epub 2017 Sep 20.

Department of Medicine, University of Colorado, School of Medicine, 12631 E 17th Ave B178, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s10620-017-4766-9DOI Listing
November 2017

NAM 2017 report: A national plan to eliminate hepatitis B and C in the United States by 2030 and the AASLD's response.

Hepatology 2017 10 30;66(4):1020-1022. Epub 2017 Aug 30.

Division of Gastroenterology, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1002/hep.29361DOI Listing
October 2017

Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy.

PLoS One 2017 17;12(10):e0186213. Epub 2017 Oct 17.

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186213PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645093PMC
October 2017

Free Fatty Acids Differentially Downregulate Chemokines in Liver Sinusoidal Endothelial Cells: Insights into Non-Alcoholic Fatty Liver Disease.

PLoS One 2016 25;11(7):e0159217. Epub 2016 Jul 25.

Department of Medicine, Division of Gastroenterology and Hepatology, University of Colorado Denver, Aurora, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159217PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959750PMC
July 2017

Galectin-9: Diverse roles in hepatic immune homeostasis and inflammation.

Hepatology 2017 07 27;66(1):271-279. Epub 2017 May 27.

Division of Gastroenterology & Hepatology, University of Colorado Denver Medical Center, Aurora, CO.

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http://dx.doi.org/10.1002/hep.29106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521806PMC
July 2017

How an alloreactive T-cell receptor achieves peptide and MHC specificity.

Proc Natl Acad Sci U S A 2017 06 1;114(24):E4792-E4801. Epub 2017 Jun 1.

Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556;

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http://dx.doi.org/10.1073/pnas.1700459114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474831PMC
June 2017

Predicting renal recovery after liver transplant with severe pretransplant subacute kidney injury: The impact of warm ischemia time.

Liver Transpl 2016 08 12;22(8):1085-91. Epub 2016 Jul 12.

Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Aurora, CO.

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http://doi.wiley.com/10.1002/lt.24488
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http://dx.doi.org/10.1002/lt.24488DOI Listing
August 2016

Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol.

Clin Gastroenterol Hepatol 2016 May 18;14(5):762-8.e1. Epub 2015 Nov 18.

Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.cgh.2015.11.005DOI Listing
May 2016

Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure.

Clin Gastroenterol Hepatol 2016 Apr 20;14(4):606-612.e3. Epub 2015 Oct 20.

Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1016/j.cgh.2015.09.040DOI Listing
April 2016

Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner.

Nat Commun 2016 Apr 21;7:11291. Epub 2016 Apr 21.

Department of Immunology and Microbiology, University of Colorado Denver at Anschutz Medical Campus, School of Medicine, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1038/ncomms11291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844673PMC
April 2016

HCV-infected cells and differentiation increase monocyte immunoregulatory galectin-9 production.

J Leukoc Biol 2016 Mar 16;99(3):495-503. Epub 2015 Oct 16.

Division of Gastroenterology and Hepatology, University of Colorado School of Medicine, Denver VA Medical Center, Denver, Colorado, USA

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http://dx.doi.org/10.1189/jlb.5A1214-582RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608045PMC
March 2016

CD4+ and CD8+ T Cell Activation in Children with Hepatitis C.

J Pediatr 2016 Mar 30;170:142-8.e1. Epub 2015 Dec 30.

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver, Aurora, CO; Eastern Colorado Veteran's Affairs Medical Center, Denver, CO. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2015.11.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833455PMC
March 2016

Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-γ Production by Altering Cellular Metabolism via Arginase-1.

J Immunol 2016 Mar 29;196(5):2283-92. Epub 2016 Jan 29.

Beirne Carter Center for Immunology Research, University of Virginia School of Medicine, Charlottesville, VA 22908; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, VA 22908;

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http://dx.doi.org/10.4049/jimmunol.1501881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761460PMC
March 2016

Consensus Interferon for Recurrent Hepatitis C Infection in Nonresponders to Peginterferon and Ribavirin After Liver Transplant.

Exp Clin Transplant 2015 Dec;13(6):543-9

Divisions of Gastroenterology, Department of Medicine, University of Colorado, Denver, Aurora, Colorado 80045, USA.

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December 2015

Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection.

PLoS One 2014 30;9(7):e103219. Epub 2014 Jul 30.

Division of Gastroenterology & Hepatology & Hepatitis C Center, University of Colorado, Aurora, Colorado, United States of America; Denver Veterans Affairs (VA), Denver, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103219PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116173PMC
November 2015

Optimizing repeat liver transplant graft utility through strategic matching of donor and recipient characteristics.

Liver Transpl 2015 Nov;21(11):1365-73

Division of Gastroenterology and Hepatology, Anschutz Medical Campus, University of Colorado, Aurora, CO.

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http://dx.doi.org/10.1002/lt.24138DOI Listing
November 2015

Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission.

J Immunol 2015 10 4;195(8):3737-47. Epub 2015 Sep 4.

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver, Aurora, CO 80045; Eastern Colorado Veteran's Affairs Medical Center, Denver, CO 80220

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http://dx.doi.org/10.4049/jimmunol.1500409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592818PMC
October 2015

The corrected donor age for hepatitis C virus-infected liver transplant recipients.

Liver Transpl 2015 Aug;21(8):1022-30

University of Colorado, Division of Gastroenterology and Hepatology, Anschutz Medical Campus, Aurora, CO.

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http://dx.doi.org/10.1002/lt.24194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809736PMC
August 2015

Hepatitis C viral infection is associated with activated cytolytic natural killer cells expressing high levels of T cell immunoglobulin- and mucin-domain-containing molecule-3.

Clin Immunol 2015 May 19;158(1):114-25. Epub 2015 Mar 19.

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, CO 80045, USA; Denver VA Medical Center, Denver, CO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.03.008DOI Listing
May 2015

Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication.

Gastroenterology 2015 Feb 4;148(2):392-402.e13. Epub 2014 Nov 4.

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado, Denver, Aurora, Colorado; Integrated Department in Immunology: University of Colorado Denver and National Jewish Health, Denver, Colorado; Eastern Colorado Veteran's Affairs Medical Center, Denver, Colorado. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765499PMC
February 2015

Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression.

PLoS One 2014 1;9(5):e95627. Epub 2014 May 1.

Integrated Department in Immunology, University of Colorado Denver and National Jewish Health, Denver, Colorado, United States of America; Division of Gastroenterology & Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America; Denver Veteran's Affairs Medical Center, Denver, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095627PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006833PMC
December 2014

Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells.

PLoS Pathog 2013 18;9(4):e1003316. Epub 2013 Apr 18.

Integrated Department in Immunology, University of Colorado Denver and National Jewish Health, Denver, Colorado, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630164PMC
January 2014

Independent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes.

J Hepatol 2013 Oct 12;59(4):701-8. Epub 2013 Jun 12.

Department of Global Health, Pathobiology Program, University of Washington, Seattle, WA, United States.

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http://dx.doi.org/10.1016/j.jhep.2013.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779522PMC
October 2013

Emerging concepts in immunity to hepatitis C virus infection.

Authors:
Hugo R Rosen

J Clin Invest 2013 Oct 1;123(10):4121-30. Epub 2013 Oct 1.

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http://dx.doi.org/10.1172/JCI67714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784533PMC
October 2013

Natural killer cells: multifaceted players with key roles in hepatitis C immunity.

Immunol Rev 2013 Sep;255(1):68-81

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, CO, USA.

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http://dx.doi.org/10.1111/imr.12090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765000PMC
September 2013

Galectin-9 functionally impairs natural killer cells in humans and mice.

J Virol 2013 May 13;87(9):4835-45. Epub 2013 Feb 13.

Division of Gastroenterology & Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver (UCD), Aurora, Colorado, USA.

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http://dx.doi.org/10.1128/JVI.01085-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624298PMC
May 2013

Race- and gender-related variation in natural killer p46 expression associated with differential anti-hepatitis C virus immunity.

Hepatology 2012 Oct;56(4):1214-22

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1002/hep.25771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458134PMC
October 2012

A novel monoclonal antibody for detection of galectin-9 in tissue sections: application to human tissues infected by oncogenic viruses.

Infect Agent Cancer 2012 Jul 17;7(1):16. Epub 2012 Jul 17.

University Paris-Sud 11, CNRS-UMR 8126, Institut de Cancérologie Gustave Roussy, 114 rue Edouard Vaillant, 94805, Villejuif cedex, France.

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http://dx.doi.org/10.1186/1750-9378-7-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464730PMC
July 2012

Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species.

Hepatology 2012 Feb;55(2):343-53

Department of Microbiology & Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1002/hep.24700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358038PMC
February 2012

Identification of osteopontin as a novel marker for early hepatocellular carcinoma.

Hepatology 2012 Feb 19;55(2):483-90. Epub 2011 Dec 19.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1002/hep.24703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914762PMC
February 2012

Interleukin (IL)-17/IL-22-producing T cells enriched within the liver of patients with chronic hepatitis C viral (HCV) infection.

Dig Dis Sci 2012 Feb 20;57(2):381-9. Epub 2011 Dec 20.

Division of Gastroenterology and Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver and National Jewish Hospital, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1007/s10620-011-1997-zDOI Listing
February 2012

Of mice and men, calcineurin inhibitors and hepatitis C.

Liver Transpl 2012 Jan;18(1):1-4

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http://dx.doi.org/10.1002/lt.22458DOI Listing
January 2012

Novel biomarker candidates to predict hepatic fibrosis in hepatitis C identified by serum proteomics.

Dig Dis Sci 2011 Nov 17;56(11):3305-15. Epub 2011 May 17.

Department of Pediatrics, University of Minnesota, 420 Delaware St. SE, MMC 185, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1007/s10620-011-1745-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181275PMC
November 2011

Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C.

Hepatology 2011 Nov 24;54(5):1559-69. Epub 2011 Aug 24.

Division of Gastroenterology & Hepatology, Hepatitis C Center, Department of Medicine, University of Colorado Denver & National Jewish Hospital, Denver, CO, USA.

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http://doi.wiley.com/10.1002/hep.24556
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http://dx.doi.org/10.1002/hep.24556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206734PMC
November 2011

Clinical practice. Chronic hepatitis C infection.

Authors:
Hugo R Rosen

N Engl J Med 2011 Jun;364(25):2429-38

Division of Gastroenterology and Hepatology, Department of Medicine, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMcp1006613
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http://dx.doi.org/10.1056/NEJMcp1006613DOI Listing
June 2011

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity.

J Clin Invest 2010 Dec 15;120(12):4546-57. Epub 2010 Nov 15.

Department of Medicine, Division of Gastroenterology and Hepatology, University of Colorado Denver, Denver, Colorado, USA.

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http://dx.doi.org/10.1172/JCI43127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994339PMC
December 2010

Innate immune function in placenta and cord blood of hepatitis C--seropositive mother-infant dyads.

PLoS One 2010 Aug 30;5(8):e12232. Epub 2010 Aug 30.

Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics Digestive Health Institute, University of Colorado School of Medicine, The Children's Hospital, Aurora, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012232PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923602PMC
August 2010

Transduction of human T cells with a novel T-cell receptor confers anti-HCV reactivity.

PLoS Pathog 2010 Jul 29;6(7):e1001018. Epub 2010 Jul 29.

Division of Transplantation, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, USA.

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http://dx.doi.org/10.1371/journal.ppat.1001018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912399PMC
July 2010

Adverse outcomes in Alaska natives who recovered from or have chronic hepatitis C infection.

Gastroenterology 2010 Mar 10;138(3):922-31.e1. Epub 2009 Nov 10.

Liver Disease and Hepatitis Program, Alaska Native Tribal Health Consortium, 4315 Diplomacy Drive, Anchorage, Alaska 99508, USA.

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http://dx.doi.org/10.1053/j.gastro.2009.10.056DOI Listing
March 2010

Functional characterization of core genes from patients with acute hepatitis C virus infection.

J Infect Dis 2010 Mar;201(6):912-22

Departments of Laboratory Medicine, University of Washington, Seattle, WA 98104, USA.

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http://dx.doi.org/10.1086/650699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827820PMC
March 2010

Comprehensive assessment of chemokine expression profiles by flow cytometry.

J Clin Invest 2010 Mar 8;120(3):907-23. Epub 2010 Feb 8.

Barbara Davis Center for Childhood Diabetes, Department of Medicine, University of Colorado Denver, Aurora, 80045-0511, USA.

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http://dx.doi.org/10.1172/JCI40645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827956PMC
March 2010

Human liver transplantation as a model to study hepatitis C virus pathogenesis.

Liver Transpl 2009 Nov;15(11):1395-411

Department of Surgery, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1002/lt.21866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954677PMC
November 2009

Frequency of gC1qR+CD4+ T cells increases during acute hepatitis C virus infection and remains elevated in patients with chronic infection.

Clin Immunol 2009 Sep 26;132(3):401-11. Epub 2009 May 26.

Beirne Carter Center for Immunology Research and Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.clim.2009.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720442PMC
September 2009

Polymorphism in the human major histocompatibility complex and early viral decline during treatment of chronic hepatitis C.

Antimicrob Agents Chemother 2009 Feb 13;53(2):615-21. Epub 2008 Oct 13.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1128/AAC.00947-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630649PMC
February 2009

Genetic markers of IgG influence the outcome of infection with hepatitis C virus.

J Infect Dis 2008 Nov;198(9):1334-6

Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1086/592282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677690PMC
November 2008

Prospective analysis of effector and regulatory CD4+ T cells in chronic HCV patients undergoing combination antiviral therapy.

J Hepatol 2008 Sep 23;49(3):329-38. Epub 2008 Jun 23.

University of Colorado Denver, School of Medicine, Division Gastroenterology & Hepatology, Hepatitis C Research Center, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1016/j.jhep.2008.05.020DOI Listing
September 2008

Transplantation immunology: what the clinician needs to know for immunotherapy.

Authors:
Hugo R Rosen

Gastroenterology 2008 May;134(6):1789-801

Division of Gastroenterology & Hepatology, Liver Transplantation, Hepatitis C Center, Department of Medicine, University of Colorado Health Sciences Center, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.02.062DOI Listing
May 2008

Cutting edge: programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: race-dependent differences.

J Immunol 2008 Mar;180(6):3637-41

Division of Gastroenterology and Hepatology, Hepatitis C Center, University of Colorado Health Sciences Center and National Jewish Hospital, Aurora, Co 80045, USA.

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http://dx.doi.org/10.4049/jimmunol.180.6.3637DOI Listing
March 2008

Spontaneous recovery in acute human hepatitis C virus infection: functional T-cell thresholds and relative importance of CD4 help.

J Virol 2008 Feb 28;82(4):1827-37. Epub 2007 Nov 28.

GI and Hepatology Division, B-158, Academic Office Building 1, 12631 East 17th Ave., Room 7614, P.O. Box 6511, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1128/JVI.01581-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258714PMC
February 2008

Pretransplantation CD56(+) innate lymphocyte populations associated with severity of hepatitis C virus recurrence.

Liver Transpl 2008 Jan;14(1):31-40

Division of Gastroenterology and Hepatology, Liver Transplantation Program Hepatitis C Research Center, University of Colorado Health Sciences Center, Denver, CO 80262, USA.

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http://dx.doi.org/10.1002/lt.21265DOI Listing
January 2008

Functional suppression by FoxP3+CD4+CD25(high) regulatory T cells during acute hepatitis C virus infection.

J Infect Dis 2008 Jan;197(1):46-57

Division of Gastroenterology and Hepatology, Hepatitis C Center, University of Colorado Health Sciences Center, GI Division, 4200 E. 9th Ave., B-158, Denver, CO 80262, USA.

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http://dx.doi.org/10.1086/523651DOI Listing
January 2008

Mechanisms of Disease: HCV-induced liver injury.

Nat Clin Pract Gastroenterol Hepatol 2007 Nov;4(11):622-34

Division of Gastroenterology and Hepatology, Department of Medicine, and Integrated Program in Immunology, University of Colorado Health Sciences Center, Denver, CO 80045, USA.

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http://www.nature.com/articles/ncpgasthep0961
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http://dx.doi.org/10.1038/ncpgasthep0961DOI Listing
November 2007

Acute hepatitis C in a contemporary US cohort: modes of acquisition and factors influencing viral clearance.

J Infect Dis 2007 Nov 31;196(10):1474-82. Epub 2007 Oct 31.

Department of Medicine, Division of Infectious Diseases, University of Washington, 325 Ninth Avenue, Seattle, WA 98104, USA.

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http://dx.doi.org/10.1086/522608DOI Listing
November 2007

Phenotypic and functional changes of cytotoxic CD56pos natural T cells determine outcome of acute hepatitis C virus infection.

J Virol 2007 Sep 6;81(17):9292-8. Epub 2007 Jun 6.

Division of Gastroenterology and Hepatology, Hepatitis C Center, University of Colorado at Denver Health Sciences Center, and National Jewish Hospital, Denver, Colorado, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.00834-07
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951454PMC
September 2007

Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction.

J Virol 2007 Sep 13;81(17):9249-58. Epub 2007 Jun 13.

Division of Gastroenterology/Hepatology, Hepatitis C Center, University of Colorado Health Sciences Center and National Jewish Hospital, Denver, CO 80262, USA.

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http://dx.doi.org/10.1128/JVI.00409-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951397PMC
September 2007

Liver retransplantation for hepatitis C: seeing is believing.

Authors:
Hugo R Rosen

Liver Transpl 2007 Sep;13(9):1217-8

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http://dx.doi.org/10.1002/lt.21191DOI Listing
September 2007

Selective decrease in hepatitis C virus-specific immunity among African Americans and outcome of antiviral therapy.

Hepatology 2007 Aug;46(2):350-8

Integrated Program in Immunology and Hepatitis C Research Center, Division of Gastroenterology and Hepatology, University of Colorado, Denver, CO, USA.

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http://dx.doi.org/10.1002/hep.21714DOI Listing
August 2007

Engulfment of apoptotic cells expressing HCV proteins leads to differential chemokine expression and STAT signaling in human dendritic cells.

Hepatology 2007 Jun;45(6):1422-32

Department of Medicine, Portland VAMC and Oregon Health & Science University, Portland, OR, USA.

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http://dx.doi.org/10.1002/hep.21637DOI Listing
June 2007

Assessment of FIBROSpect II to detect hepatic fibrosis in chronic hepatitis C patients.

Am J Med 2007 Mar;120(3):280.e9-14

Division of Gastroenterology and Hepatology, Oregon Health & Science University, Portland, Oregon 97201, USA.

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March 2007

A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection.

Proc Natl Acad Sci U S A 2007 Jan 10;104(3):985-90. Epub 2007 Jan 10.

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0609954104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783426PMC
January 2007

Acute rejection in HCV-infected liver transplant recipients: The great conundrum.

Liver Transpl 2006 Nov;12(11 Suppl 2):S38-47

Division of Gastroenterology and Hepatology, Liver Transplantation Program and Hepatitis C Research Center, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA.

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http://dx.doi.org/10.1002/lt.20944DOI Listing
November 2006

Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence.

Hepatology 2006 Nov;44(5):1098-109

Division of Gastroenterology & Hepatology, Hepatitis C Center, and Integrated Program in Immunology, University of Colorado Health Sciences Center & National Jewish Hospital, Denver, CO, USA.

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http://dx.doi.org/10.1002/hep.21365DOI Listing
November 2006

Differential antigenic hierarchy associated with spontaneous recovery from hepatitis C virus infection: implications for vaccine design.

J Infect Dis 2006 Aug 12;194(4):454-63. Epub 2006 Jul 12.

Division of Gastroenterology and Hepatology, Hepatitis C Center, and Integrated Program in Immunology, University of Colorado Health Sciences Center and National Jewish Hospital, Denver, 80262, USA.

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http://dx.doi.org/10.1086/505714DOI Listing
August 2006

Liver transplantation for hepatocellular carcinoma: a survey of practices.

J Clin Gastroenterol 2006 Aug;40(7):643-7

Department of Internal Medicine, Oregon Health and Sciences University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1097/00004836-200608000-00018DOI Listing
August 2006

Treatment of HCV recurrence: do the pretransplantation rules apply?

Liver Transpl 2006 Jul;12(7):1044-8

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http://dx.doi.org/10.1002/lt.20783DOI Listing
July 2006

Diagnosis and management of allograft failure.

Clin Liver Dis 2006 May;10(2):407-35, x

Division of Gastroenterology and Hepatology, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, B154, Denver, CO 80262, USA.

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May 2006