Publications by authors named "Hugh S Gannon"

7Publications

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells.

Authors:
Hugh S Gannon Tao Zou Michael K Kiessling Galen F Gao Diana Cai Peter S Choi Alexandru P Ivan Ilana Buchumenski Ashton C Berger Jonathan T Goldstein Andrew D Cherniack Francisca Vazquez Aviad Tsherniak Erez Y Levanon William C Hahn Matthew Meyerson

Nat Commun 2018 12 21;9(1):5450. Epub 2018 Dec 21.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.

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December 2018

Mutational processes shape the landscape of TP53 mutations in human cancer.

Authors:
Andrew O Giacomelli Xiaoping Yang Robert E Lintner James M McFarland Marc Duby Jaegil Kim Thomas P Howard David Y Takeda Seav Huong Ly Eejung Kim Hugh S Gannon Brian Hurhula Ted Sharpe Amy Goodale Briana Fritchman Scott Steelman Francisca Vazquez Aviad Tsherniak Andrew J Aguirre John G Doench Federica Piccioni Charles W M Roberts Matthew Meyerson Gad Getz Cory M Johannessen David E Root William C Hahn

Nat Genet 2018 10 17;50(10):1381-1387. Epub 2018 Sep 17.

Dana-Farber Cancer Institute, Boston, MA, USA.

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October 2018

Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.

Authors:
Michael I Carr Justine E Roderick Hugh S Gannon Michelle A Kelliher Stephen N Jones

Cell Rep 2016 09 25;16(10):2618-2629. Epub 2016 Aug 25.

Department of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA. Electronic address:

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September 2016

Identification of an "Exceptional Responder" Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy.

Authors:
Hugh S Gannon Nathan Kaplan Aviad Tsherniak Francisca Vazquez Barbara A Weir William C Hahn Matthew Meyerson

Mol Cancer Res 2016 Feb 18;14(2):207-15. Epub 2015 Nov 18.

Broad Institute of Harvard and MIT, Cambridge, Massachusetts. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Harvard Medical School, Boston, Massachusetts.

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February 2016

Using Mouse Models to Explore MDM-p53 Signaling in Development, Cell Growth, and Tumorigenesis.

Authors:
Hugh S Gannon Stephen N Jones

Genes Cancer 2012 Mar;3(3-4):209-18

University of Massachusetts Medical School, Worcester, MA, USA.

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March 2012

ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice.

Authors:
Hugh S Gannon Bruce A Woda Stephen N Jones

Cancer Cell 2012 May;21(5):668-79

Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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May 2012

Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin.

Authors:
Hugh S Gannon Lawrence A Donehower Stephen Lyle Stephen N Jones

Dev Biol 2011 May 17;353(1):1-9. Epub 2011 Feb 17.

Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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May 2011