Hugh Gurling

Hugh Gurling

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Hugh Gurling

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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Authors:
Christian R Marshall Daniel P Howrigan Daniele Merico Bhooma Thiruvahindrapuram Wenting Wu Douglas S Greer Danny Antaki Aniket Shetty Peter A Holmans Dalila Pinto Madhusudan Gujral William M Brandler Dheeraj Malhotra Zhouzhi Wang Karin V Fuentes Fajarado Michelle S Maile Stephan Ripke Ingrid Agartz Margot Albus Madeline Alexander Farooq Amin Joshua Atkins Silviu A Bacanu Richard A Belliveau Sarah E Bergen Marcelo Bertalan Elizabeth Bevilacqua Tim B Bigdeli Donald W Black Richard Bruggeman Nancy G Buccola Randy L Buckner Brendan Bulik-Sullivan William Byerley Wiepke Cahn Guiqing Cai Murray J Cairns Dominique Campion Rita M Cantor Vaughan J Carr Noa Carrera Stanley V Catts Kimberley D Chambert Wei Cheng C Robert Cloninger David Cohen Paul Cormican Nick Craddock Benedicto Crespo-Facorro James J Crowley David Curtis Michael Davidson Kenneth L Davis Franziska Degenhardt Jurgen Del Favero Lynn E DeLisi Dimitris Dikeos Timothy Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Peter Eichhammer Johan Eriksson Valentina Escott-Price Laurent Essioux Ayman H Fanous Kai-How Farh Martilias S Farrell Josef Frank Lude Franke Robert Freedman Nelson B Freimer Joseph I Friedman Andreas J Forstner Menachem Fromer Giulio Genovese Lyudmila Georgieva Elliot S Gershon Ina Giegling Paola Giusti-Rodríguez Stephanie Godard Jacqueline I Goldstein Jacob Gratten Lieuwe de Haan Marian L Hamshere Mark Hansen Thomas Hansen Vahram Haroutunian Annette M Hartmann Frans A Henskens Stefan Herms Joel N Hirschhorn Per Hoffmann Andrea Hofman Hailiang Huang Masashi Ikeda Inge Joa Anna K Kähler René S Kahn Luba Kalaydjieva Juha Karjalainen David Kavanagh Matthew C Keller Brian J Kelly James L Kennedy Yunjung Kim James A Knowles Bettina Konte Claudine Laurent Phil Lee S Hong Lee Sophie E Legge Bernard Lerer Deborah L Levy Kung-Yee Liang Jeffrey Lieberman Jouko Lönnqvist Carmel M Loughland Patrik K E Magnusson Brion S Maher Wolfgang Maier Jacques Mallet Manuel Mattheisen Morten Mattingsdal Robert W McCarley Colm McDonald Andrew M McIntosh Sandra Meier Carin J Meijer Ingrid Melle Raquelle I Mesholam-Gately Andres Metspalu Patricia T Michie Lili Milani Vihra Milanova Younes Mokrab Derek W Morris Bertram Müller-Myhsok Kieran C Murphy Robin M Murray Inez Myin-Germeys Igor Nenadic Deborah A Nertney Gerald Nestadt Kristin K Nicodemus Laura Nisenbaum Annelie Nordin Eadbhard O'Callaghan Colm O'Dushlaine Sang-Yun Oh Ann Olincy Line Olsen F Anthony O'Neill Jim Van Os Christos Pantelis George N Papadimitriou Elena Parkhomenko Michele T Pato Tiina Paunio Diana O Perkins Tune H Pers Olli Pietiläinen Jonathan Pimm Andrew J Pocklington John Powell Alkes Price Ann E Pulver Shaun M Purcell Digby Quested Henrik B Rasmussen Abraham Reichenberg Mark A Reimers Alexander L Richards Joshua L Roffman Panos Roussos Douglas M Ruderfer Veikko Salomaa Alan R Sanders Adam Savitz Ulrich Schall Thomas G Schulze Sibylle G Schwab Edward M Scolnick Rodney J Scott Larry J Seidman Jianxin Shi Jeremy M Silverman Jordan W Smoller Erik Söderman Chris C A Spencer Eli A Stahl Eric Strengman Jana Strohmaier T Scott Stroup Jaana Suvisaari Dragan M Svrakic Jin P Szatkiewicz Srinivas Thirumalai Paul A Tooney Juha Veijola Peter M Visscher John Waddington Dermot Walsh Bradley T Webb Mark Weiser Dieter B Wildenauer Nigel M Williams Stephanie Williams Stephanie H Witt Aaron R Wolen Brandon K Wormley Naomi R Wray Jing Qin Wu Clement C Zai Rolf Adolfsson Ole A Andreassen Douglas H R Blackwood Elvira Bramon Joseph D Buxbaum Sven Cichon David A Collier Aiden Corvin Mark J Daly Ariel Darvasi Enrico Domenici Tõnu Esko Pablo V Gejman Michael Gill Hugh Gurling Christina M Hultman Nakao Iwata Assen V Jablensky Erik G Jönsson Kenneth S Kendler George Kirov Jo Knight Douglas F Levinson Qingqin S Li Steven A McCarroll Andrew McQuillin Jennifer L Moran Bryan J Mowry Markus M Nöthen Roel A Ophoff Michael J Owen Aarno Palotie Carlos N Pato Tracey L Petryshen Danielle Posthuma Marcella Rietschel Brien P Riley Dan Rujescu Pamela Sklar David St Clair James T R Walters Thomas Werge Patrick F Sullivan Michael C O'Donovan Stephen W Scherer Benjamin M Neale Jonathan Sebat

Nat Genet 2017 01 21;49(1):27-35. Epub 2016 Nov 21.

Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ng.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737772PMC
January 2017

Genetic variant analysis of the putative regulatory regions of the LRRC7 gene in bipolar disorder.

Psychiatr Genet 2016 Apr;26(2):99-100

Molecular Psychiatry Laboratory, Mental Health Neuroscience Department, Division of Psychiatry, University College London, London, UK.

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http://dx.doi.org/10.1097/YPG.0000000000000119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766723PMC
April 2016

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.

Authors:
S Hong Lee Enda M Byrne Christina M Hultman Anna Kähler Anna A E Vinkhuyzen Stephan Ripke Ole A Andreassen Thomas Frisell Alexander Gusev Xinli Hu Robert Karlsson Vasilis X Mantzioris John J McGrath Divya Mehta Eli A Stahl Qiongyi Zhao Kenneth S Kendler Patrick F Sullivan Alkes L Price Michael O'Donovan Yukinori Okada Bryan J Mowry Soumya Raychaudhuri Naomi R Wray William Byerley Wiepke Cahn Rita M Cantor Sven Cichon Paul Cormican David Curtis Srdjan Djurovic Valentina Escott-Price Pablo V Gejman Lyudmila Georgieva Ina Giegling Thomas F Hansen Andrés Ingason Yunjung Kim Bettina Konte Phil H Lee Andrew McIntosh Andrew McQuillin Derek W Morris Markus M Nöthen Colm O'Dushlaine Ann Olincy Line Olsen Carlos N Pato Michele T Pato Benjamin S Pickard Danielle Posthuma Henrik B Rasmussen Marcella Rietschel Dan Rujescu Thomas G Schulze Jeremy M Silverman Srinivasa Thirumalai Thomas Werge Ingrid Agartz Farooq Amin Maria H Azevedo Nicholas Bass Donald W Black Douglas H R Blackwood Richard Bruggeman Nancy G Buccola Khalid Choudhury Robert C Cloninger Aiden Corvin Nicholas Craddock Mark J Daly Susmita Datta Gary J Donohoe Jubao Duan Frank Dudbridge Ayman Fanous Robert Freedman Nelson B Freimer Marion Friedl Michael Gill Hugh Gurling Lieuwe De Haan Marian L Hamshere Annette M Hartmann Peter A Holmans René S Kahn Matthew C Keller Elaine Kenny George K Kirov Lydia Krabbendam Robert Krasucki Jacob Lawrence Todd Lencz Douglas F Levinson Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Patrik K E Magnusson Wolfgang Maier Anil K Malhotra Manuel Mattheisen Morten Mattingsdal Steven A McCarroll Helena Medeiros Ingrid Melle Vihra Milanova Inez Myin-Germeys Benjamin M Neale Roel A Ophoff Michael J Owen Jonathan Pimm Shaun M Purcell Vinay Puri Digby J Quested Lizzy Rossin Douglas Ruderfer Alan R Sanders Jianxin Shi Pamela Sklar David St Clair T Scott Stroup Jim Van Os Peter M Visscher Durk Wiersma Stanley Zammit S Louis Bridges Hyon K Choi Marieke J H Coenen Niek de Vries Philippe Dieud Jeffrey D Greenberg Tom W J Huizinga Leonid Padyukov Katherine A Siminovitch Paul P Tak Jane Worthington Philip L De Jager Joshua C Denny Peter K Gregersen Lars Klareskog Xavier Mariette Robert M Plenge Mart van Laar Piet van Riel

Int J Epidemiol 2015 Oct;44(5):1706-21

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http://dx.doi.org/10.1093/ije/dyv136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881824PMC
October 2015

Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder.

Bipolar Disord 2015 Mar 23;17(2):205-11. Epub 2014 Jul 23.

Department of Biomedicine, Institute of Human Genetics, Aarhus University, Aarhus, Denmark; Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Risskov, Denmark; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark; Centre for Integrative Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1111/bdi.12239DOI Listing
March 2015

Quantitative and molecular genetics of ADHD.

Curr Top Behav Neurosci 2012 ;9:239-72

MRC Social Genetic and Developmental Psychiatry, Institute of Psychiatry, Kings College London, London, UK,

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http://dx.doi.org/10.1007/7854_2011_155DOI Listing
January 2015

A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder.

Am J Hum Genet 2014 Dec 26;95(6):744-53. Epub 2014 Nov 26.

Center for Psychiatric Genetics, Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, IL 60201, USA; Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ajhg.2014.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259974PMC
December 2014

Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition.

Nat Commun 2013 ;4:2816

1] Institute of Cellular Medicine, The Medical School, Newcastle University, 4th Floor William Leech Building, Framlington Place, Newcastle Upon Tyne NE2 4HH, UK [2] Mammalian Genetics Unit, MRC Harwell, Oxford OX11 0RD, UK [3] Department of Gastroenterology and Hepatology, Imperial College, St Mary's Hospital Campus, Praed Street, London W2 1NY, UK [4].

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http://dx.doi.org/10.1038/ncomms3816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843143PMC
July 2014

Evidence for genetic susceptibility to the alcohol dependence syndrome from the thiamine transporter 2 gene solute carrier SLC19A3.

Psychiatr Genet 2014 Jun;24(3):122-3

aMolecular Psychiatry Laboratory, Division of Psychiatry, Faculty of Brain Sciences, University College London bUCL Institute for Liver & Digestive Health, Royal Free Campus, University College London cNational Addiction Centre and Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry dCity and Hackney Centre for Mental Health, East London NHS Foundation Trust, Homerton Row, London eBexley Substance Misuse Services, South London & Maudsley NHS Trust, Erith Health Centre, Kent fGatehouse Alcohol Clinic and Max Glatt Unit, Central and North West London NHS Foundation Trust, St Bernards Hospital, Middlesex gGartnavel Royal Hospital hHomeless Addictions Team, NHS Greater Glasgow and Clyde, Glasgow iNewcastle and North Tyneside Addictions Service, Plummer Court, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1097/YPG.0000000000000025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004634PMC
June 2014

Allelic association, DNA resequencing and copy number variation at the metabotropic glutamate receptor GRM7 gene locus in bipolar disorder.

Am J Med Genet B Neuropsychiatr Genet 2014 Jun 8;165B(4):365-72. Epub 2014 May 8.

Molecular Psychiatry Laboratory, Mental Health Sciences Unit, Faculty of Brain Sciences, University College London, London, UK.

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http://dx.doi.org/10.1002/ajmg.b.32239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231221PMC
June 2014

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Authors:
S Hong Lee Stephan Ripke Benjamin M Neale Stephen V Faraone Shaun M Purcell Roy H Perlis Bryan J Mowry Anita Thapar Michael E Goddard John S Witte Devin Absher Ingrid Agartz Huda Akil Farooq Amin Ole A Andreassen Adebayo Anjorin Richard Anney Verneri Anttila Dan E Arking Philip Asherson Maria H Azevedo Lena Backlund Judith A Badner Anthony J Bailey Tobias Banaschewski Jack D Barchas Michael R Barnes Thomas B Barrett Nicholas Bass Agatino Battaglia Michael Bauer Mònica Bayés Frank Bellivier Sarah E Bergen Wade Berrettini Catalina Betancur Thomas Bettecken Joseph Biederman Elisabeth B Binder Donald W Black Douglas H R Blackwood Cinnamon S Bloss Michael Boehnke Dorret I Boomsma Gerome Breen René Breuer Richard Bruggeman Paul Cormican Nancy G Buccola Jan K Buitelaar William E Bunney Joseph D Buxbaum William F Byerley Enda M Byrne Sian Caesar Wiepke Cahn Rita M Cantor Miguel Casas Aravinda Chakravarti Kimberly Chambert Khalid Choudhury Sven Cichon C Robert Cloninger David A Collier Edwin H Cook Hilary Coon Bru Cormand Aiden Corvin William H Coryell David W Craig Ian W Craig Jennifer Crosbie Michael L Cuccaro David Curtis Darina Czamara Susmita Datta Geraldine Dawson Richard Day Eco J De Geus Franziska Degenhardt Srdjan Djurovic Gary J Donohoe Alysa E Doyle Jubao Duan Frank Dudbridge Eftichia Duketis Richard P Ebstein Howard J Edenberg Josephine Elia Sean Ennis Bruno Etain Ayman Fanous Anne E Farmer I Nicol Ferrier Matthew Flickinger Eric Fombonne Tatiana Foroud Josef Frank Barbara Franke Christine Fraser Robert Freedman Nelson B Freimer Christine M Freitag Marion Friedl Louise Frisén Louise Gallagher Pablo V Gejman Lyudmila Georgieva Elliot S Gershon Daniel H Geschwind Ina Giegling Michael Gill Scott D Gordon Katherine Gordon-Smith Elaine K Green Tiffany A Greenwood Dorothy E Grice Magdalena Gross Detelina Grozeva Weihua Guan Hugh Gurling Lieuwe De Haan Jonathan L Haines Hakon Hakonarson Joachim Hallmayer Steven P Hamilton Marian L Hamshere Thomas F Hansen Annette M Hartmann Martin Hautzinger Andrew C Heath Anjali K Henders Stefan Herms Ian B Hickie Maria Hipolito Susanne Hoefels Peter A Holmans Florian Holsboer Witte J Hoogendijk Jouke-Jan Hottenga Christina M Hultman Vanessa Hus Andrés Ingason Marcus Ising Stéphane Jamain Edward G Jones Ian Jones Lisa Jones Jung-Ying Tzeng Anna K Kähler René S Kahn Radhika Kandaswamy Matthew C Keller James L Kennedy Elaine Kenny Lindsey Kent Yunjung Kim George K Kirov Sabine M Klauck Lambertus Klei James A Knowles Martin A Kohli Daniel L Koller Bettina Konte Ania Korszun Lydia Krabbendam Robert Krasucki Jonna Kuntsi Phoenix Kwan Mikael Landén Niklas Långström Mark Lathrop Jacob Lawrence William B Lawson Marion Leboyer David H Ledbetter Phil H Lee Todd Lencz Klaus-Peter Lesch Douglas F Levinson Cathryn M Lewis Jun Li Paul Lichtenstein Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Chunyu Liu Falk W Lohoff Sandra K Loo Catherine Lord Jennifer K Lowe Susanne Lucae Donald J MacIntyre Pamela A F Madden Elena Maestrini Patrik K E Magnusson Pamela B Mahon Wolfgang Maier Anil K Malhotra Shrikant M Mane Christa L Martin Nicholas G Martin Manuel Mattheisen Keith Matthews Morten Mattingsdal Steven A McCarroll Kevin A McGhee James J McGough Patrick J McGrath Peter McGuffin Melvin G McInnis Andrew McIntosh Rebecca McKinney Alan W McLean Francis J McMahon William M McMahon Andrew McQuillin Helena Medeiros Sarah E Medland Sandra Meier Ingrid Melle Fan Meng Jobst Meyer Christel M Middeldorp Lefkos Middleton Vihra Milanova Ana Miranda Anthony P Monaco Grant W Montgomery Jennifer L Moran Daniel Moreno-De-Luca Gunnar Morken Derek W Morris Eric M Morrow Valentina Moskvina Pierandrea Muglia Thomas W Mühleisen Walter J Muir Bertram Müller-Myhsok Michael Murtha Richard M Myers Inez Myin-Germeys Michael C Neale Stan F Nelson Caroline M Nievergelt Ivan Nikolov Vishwajit Nimgaonkar Willem A Nolen Markus M Nöthen John I Nurnberger Evaristus A Nwulia Dale R Nyholt Colm O'Dushlaine Robert D Oades Ann Olincy Guiomar Oliveira Line Olsen Roel A Ophoff Urban Osby Michael J Owen Aarno Palotie Jeremy R Parr Andrew D Paterson Carlos N Pato Michele T Pato Brenda W Penninx Michele L Pergadia Margaret A Pericak-Vance Benjamin S Pickard Jonathan Pimm Joseph Piven Danielle Posthuma James B Potash Fritz Poustka Peter Propping Vinay Puri Digby J Quested Emma M Quinn Josep Antoni Ramos-Quiroga Henrik B Rasmussen Soumya Raychaudhuri Karola Rehnström Andreas Reif Marta Ribasés John P Rice Marcella Rietschel Kathryn Roeder Herbert Roeyers Lizzy Rossin Aribert Rothenberger Guy Rouleau Douglas Ruderfer Dan Rujescu Alan R Sanders Stephan J Sanders Susan L Santangelo Joseph A Sergeant Russell Schachar Martin Schalling Alan F Schatzberg William A Scheftner Gerard D Schellenberg Stephen W Scherer Nicholas J Schork Thomas G Schulze Johannes Schumacher Markus Schwarz Edward Scolnick Laura J Scott Jianxin Shi Paul D Shilling Stanley I Shyn Jeremy M Silverman Susan L Slager Susan L Smalley Johannes H Smit Erin N Smith Edmund J S Sonuga-Barke David St Clair Matthew State Michael Steffens Hans-Christoph Steinhausen John S Strauss Jana Strohmaier T Scott Stroup James S Sutcliffe Peter Szatmari Szabocls Szelinger Srinivasa Thirumalai Robert C Thompson Alexandre A Todorov Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Jim Van Os Astrid M Vicente Veronica J Vieland John B Vincent Peter M Visscher Christopher A Walsh Thomas H Wassink Stanley J Watson Myrna M Weissman Thomas Werge Thomas F Wienker Ellen M Wijsman Gonneke Willemsen Nigel Williams A Jeremy Willsey Stephanie H Witt Wei Xu Allan H Young Timothy W Yu Stanley Zammit Peter P Zandi Peng Zhang Frans G Zitman Sebastian Zöllner Bernie Devlin John R Kelsoe Pamela Sklar Mark J Daly Michael C O'Donovan Nicholas Craddock Patrick F Sullivan Jordan W Smoller Kenneth S Kendler Naomi R Wray

Nat Genet 2013 Sep 11;45(9):984-94. Epub 2013 Aug 11.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.2711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800159PMC
September 2013

Act now against new NHS competition regulations: an open letter to the BMA and the Academy of Medical Royal Colleges calls on them to make a joint public statement of opposition to the amended section 75 regulations.

Authors:
Jacky Davis Ian Banks David Wrigley Clive Peedell Alyson Pollock Klim McPherson Martin McKee William L Irving Peter Crome Trisha Greenhalgh Walter Holland David Evans Alan Maryon-Davis Alan Smyth Peter Fleming Michel Coleman Deborah J Sharp Peter Whincup Stuart Logan Derek Cook Robert Moore Salman Rawaf J McEewen Robert West John S Yudkin Aileen Clarke Nick Finer Paola Domizio Clare Bambra Anna Jones Gene Feder Alex Scott-Samuel Louise Irvine Ajay Sharma Mike Fitchett Kambiz Boomla Jonathan Folb Ashish Paul David McCoy Ray Tallis Jilla Burgess-Allen Mark Edwards Jonathon Tomlinson Deborah Colvin Jonathan Gore Kirsten Brown Sarah Mitchel Alice Lau Mel Sayer Leon Clark Ruth Silverman Saul Marmot Daniel Rainbow Lucy Carter Nick Mann Richard Fielding Jane Logan Louise Tebboth Natasha Arnold Kate Stobbart Kate Cabot Sarah Finer Martin Edwards David Davies Helen Buttivant Sebastian Kraemer Jo Newell Alun Griffiths Richard Fitzgerald Robert Macgibbon Alan Lee A F Macklon Esther Hobson David Jenner Bobbie Jacobson Alison Timmis Asad Salim John Evans-Jones Woody Caan Ninaad Awsare Neil Pride Ruth Suckling Catherine Bratty Brian Rossiter David Hawkins Jonny Currie Corinne Camilleri-Ferrante Jonathan Fluxman Osman Bhatti James Anson Robert Etherington David Lawrence Henry Fell Edward Clarke Julian Ormerod Oliver Ormerod Maggie Ireland John A T Duncan Rajiv Chandy Jennifer Mindell Paul Mullen Phillip Bennett-Richards Julie Hirst E Murphy P Martin Simon Lowes Peter Fleming Richard Grunewald Joanne Reeve Martin Schweiger Jonathan Coates George Farrelly M A Chamberlain Geoffrey Lewis Jane Young Brian Scott John Gibbs Aileen Landers Pete Deveson Grant Ingrams Martha Leigh Jeff Gawler Amy Ford Jonathan Nixon Margaret McCartney David Bareford Surinder Singh Kate Lockwood Michael Cripwell Peter Ehrhardt David Bell Pam Wortley Laurie Tomlinson Julie Hotchkiss Steven Ford Gill Turner Gerard Reissman David Lewis Chris Johnstone Mike Tomson Payam Torabi David Bell D Tomson Alex Tulloch Sally Johnston Jane Dickinson Elisabeth McElderry Wendy Ross Kim Holt Mary Logan Hilary Klonin David Jenner Jude Danby V Goodger John Puntis Harriet Dickson Derek A Gould Anna Livingstone Dianne Lefevre Bryony Kendall G Singh Peter Hall Jonathan Darling Adrian N Hamlyn Anita Patel Jonathan Erskine Brian Fisher Richard Hughes Clare Highton Helen Venning Ron Singer Steve Brearey Jim Sikorski David Paintin John Feehally Wendy Savage Kathy McAdam Freud Victoria J Holt Alison Gill Tony Waterston Richard de Souza Nicholas Hopkinson Mike Beadsworth Andrea Franks Helen Daley Paul Cullinan Adriana Basarab Jonathan Folb Hugh Gurling Pam Zinkin Simon Kirwin Ernst Buhrs Raymond Brown Andrew West Gary Marlowe Griffith Fellows John Main Jackie Applebee M Koperski Phil Jones Alison Macfarlane Naomi Beer Rebecca Mason Robert West Maggie Eisner Alison Smailes Philip Timms David Knight Coral Jones Barbara Wesby Laura Lyttelton Richard Morrison David Bossano Jonathan Walker Gerry Davies Peter Godfrey Ingrid Wolfe Emmanuel Nsutebu Nicola Stevenson Sheila Cheeroth Jo Miller Guy Johnson R Noor Alyson Hall David Bostock Benedict Michael John Sharvill Jamie Macpherson David Lewis Richard Ma John Middleton Anne Jeffreys Jim Cole John P Boswell Bob Bury Sally Mitchison Ann-Louise Kinmonth Gail Young Iain Maclennan Pat Munday

BMJ 2013 Mar 20;346:f1819. Epub 2013 Mar 20.

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http://dx.doi.org/10.1136/bmj.f1819DOI Listing
March 2013

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease.

J Alzheimers Dis 2012 ;28(2):377-87

MRC Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.3233/JAD-2011-110824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118466PMC
May 2012

Sequencing of the ANKYRIN 3 gene (ANK3) encoding ankyrin G in bipolar disorder reveals a non-conservative amino acid change in a short isoform of ankyrin G.

Am J Med Genet B Neuropsychiatr Genet 2012 Apr 10;159B(3):328-35. Epub 2012 Feb 10.

Molecular Psychiatry Laboratory, Mental Health Sciences Unit, University College London, London, UK.

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http://doi.wiley.com/10.1002/ajmg.b.32030
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http://dx.doi.org/10.1002/ajmg.b.32030DOI Listing
April 2012

Tests of linkage and allelic association between markers in the 1p36 PRKCZ (protein kinase C zeta) gene region and bipolar affective disorder.

Am J Med Genet B Neuropsychiatr Genet 2012 Mar 9;159B(2):201-9. Epub 2012 Jan 9.

Molecular Psychiatry Laboratory, Research Department of Mental Health Sciences, University College London, UK.

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http://dx.doi.org/10.1002/ajmg.b.32014DOI Listing
March 2012

Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample.

Eur J Hum Genet 2011 May 5;19(5):588-92. Epub 2011 Jan 5.

Molecular Psychiatry Laboratory, Windeyer Institute of Medical Sciences, Research Department of Mental Health Sciences, University College London, London, UK.

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http://www.nature.com/articles/ejhg2010221
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http://dx.doi.org/10.1038/ejhg.2010.221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083610PMC
May 2011

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

Authors:
Paul Hollingworth Denise Harold Rebecca Sims Amy Gerrish Jean-Charles Lambert Minerva M Carrasquillo Richard Abraham Marian L Hamshere Jaspreet Singh Pahwa Valentina Moskvina Kimberley Dowzell Nicola Jones Alexandra Stretton Charlene Thomas Alex Richards Dobril Ivanov Caroline Widdowson Jade Chapman Simon Lovestone John Powell Petroula Proitsi Michelle K Lupton Carol Brayne David C Rubinsztein Michael Gill Brian Lawlor Aoibhinn Lynch Kristelle S Brown Peter A Passmore David Craig Bernadette McGuinness Stephen Todd Clive Holmes David Mann A David Smith Helen Beaumont Donald Warden Gordon Wilcock Seth Love Patrick G Kehoe Nigel M Hooper Emma R L C Vardy John Hardy Simon Mead Nick C Fox Martin Rossor John Collinge Wolfgang Maier Frank Jessen Eckart Rüther Britta Schürmann Reiner Heun Heike Kölsch Hendrik van den Bussche Isabella Heuser Johannes Kornhuber Jens Wiltfang Martin Dichgans Lutz Frölich Harald Hampel John Gallacher Michael Hüll Dan Rujescu Ina Giegling Alison M Goate John S K Kauwe Carlos Cruchaga Petra Nowotny John C Morris Kevin Mayo Kristel Sleegers Karolien Bettens Sebastiaan Engelborghs Peter P De Deyn Christine Van Broeckhoven Gill Livingston Nicholas J Bass Hugh Gurling Andrew McQuillin Rhian Gwilliam Panagiotis Deloukas Ammar Al-Chalabi Christopher E Shaw Magda Tsolaki Andrew B Singleton Rita Guerreiro Thomas W Mühleisen Markus M Nöthen Susanne Moebus Karl-Heinz Jöckel Norman Klopp H-Erich Wichmann V Shane Pankratz Sigrid B Sando Jan O Aasly Maria Barcikowska Zbigniew K Wszolek Dennis W Dickson Neill R Graff-Radford Ronald C Petersen Cornelia M van Duijn Monique M B Breteler M Arfan Ikram Anita L DeStefano Annette L Fitzpatrick Oscar Lopez Lenore J Launer Sudha Seshadri Claudine Berr Dominique Campion Jacques Epelbaum Jean-François Dartigues Christophe Tzourio Annick Alpérovitch Mark Lathrop Thomas M Feulner Patricia Friedrich Caterina Riehle Michael Krawczak Stefan Schreiber Manuel Mayhaus S Nicolhaus Stefan Wagenpfeil Stacy Steinberg Hreinn Stefansson Kari Stefansson Jon Snaedal Sigurbjörn Björnsson Palmi V Jonsson Vincent Chouraki Benjamin Genier-Boley Mikko Hiltunen Hilkka Soininen Onofre Combarros Diana Zelenika Marc Delepine Maria J Bullido Florence Pasquier Ignacio Mateo Ana Frank-Garcia Elisa Porcellini Olivier Hanon Eliecer Coto Victoria Alvarez Paolo Bosco Gabriele Siciliano Michelangelo Mancuso Francesco Panza Vincenzo Solfrizzi Benedetta Nacmias Sandro Sorbi Paola Bossù Paola Piccardi Beatrice Arosio Giorgio Annoni Davide Seripa Alberto Pilotto Elio Scarpini Daniela Galimberti Alexis Brice Didier Hannequin Federico Licastro Lesley Jones Peter A Holmans Thorlakur Jonsson Matthias Riemenschneider Kevin Morgan Steven G Younkin Michael J Owen Michael O'Donovan Philippe Amouyel Julie Williams

Nat Genet 2011 May 3;43(5):429-35. Epub 2011 Apr 3.

Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Neurosciences and Mental Health Research Institute, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1038/ng.803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084173PMC
May 2011

Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder.

Am J Med Genet B Neuropsychiatr Genet 2011 Mar 13;156(2):177-87. Epub 2011 Jan 13.

Molecular Psychiatry Laboratory, Department of Mental Health Sciences, Windeyer Institute of Medical Sciences, University College London, 46 Cleveland Street, London, UK.

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http://doi.wiley.com/10.1002/ajmg.b.31153
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http://dx.doi.org/10.1002/ajmg.b.31153DOI Listing
March 2011

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

PLoS One 2010 Nov 15;5(11):e13950. Epub 2010 Nov 15.

Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Cardiff, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013950PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981526PMC
November 2010

Three-dimensional textural analysis of brain images reveals distributed grey-matter abnormalities in schizophrenia.

Eur Radiol 2010 Apr 16;20(4):941-8. Epub 2009 Sep 16.

Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, UK.

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http://dx.doi.org/10.1007/s00330-009-1605-1DOI Listing
April 2010

Genetics of attention-deficit hyperactivity disorder (ADHD).

Neuropharmacology 2009 Dec 26;57(7-8):590-600. Epub 2009 Aug 26.

Molecular Psychiatry Laboratory, Research Department of Mental Health Sciences, Windeyer Institute of Medical Sciences, University College London Medical School, 46 Cleveland Street, London W1T 4JF, UK.

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http://dx.doi.org/10.1016/j.neuropharm.2009.08.011DOI Listing
December 2009

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.

Nat Genet 2009 Oct 6;41(10):1088-93. Epub 2009 Sep 6.

Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1038/ng.440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845877PMC
October 2009

Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia.

Behav Brain Funct 2009 Jul 8;5:28. Epub 2009 Jul 8.

Molecular Psychiatry Laboratory, Research Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, 46 Cleveland Street, London, W1T 4JF, UK.

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http://dx.doi.org/10.1186/1744-9081-5-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717980PMC
July 2009

Molecular genetics of alcohol-related brain damage.

Alcohol Alcohol 2009 Mar-Apr;44(2):166-70. Epub 2008 Dec 18.

Bexley Substance Misuse Service, South London and Mausdley NHS Trust, London, UK.

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http://dx.doi.org/10.1093/alcalc/agn101DOI Listing
April 2009

Confirmation of the genetic association between the U2AF homology motif (UHM) kinase 1 (UHMK1) gene and schizophrenia on chromosome 1q23.3.

Eur J Hum Genet 2008 Oct 16;16(10):1275-82. Epub 2008 Apr 16.

Molecular Psychiatry Laboratory, Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, London, UK.

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http://dx.doi.org/10.1038/ejhg.2008.76DOI Listing
October 2008

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

Nat Genet 2008 Sep;40(9):1056-8

Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://research.mssm.edu/statgen/library/ferreira-2008-bipol
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http://www.nature.com/doifinder/10.1038/ng.209
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703780PMC
September 2008

A microarray gene expression study of the molecular pharmacology of lithium carbonate on mouse brain mRNA to understand the neurobiology of mood stabilization and treatment of bipolar affective disorder.

Pharmacogenet Genomics 2007 Aug;17(8):605-17

Molecular Psychiatry Laboratory, Department of Mental Health Sciences, Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, London, UK.

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http://dx.doi.org/10.1097/FPC.0b013e328011b5b2DOI Listing
August 2007

The importance of alcohol misuse, malnutrition and genetic susceptibility on brain growth and plasticity.

Neurosci Biobehav Rev 2007 5;31(2):212-20. Epub 2006 Sep 5.

Molecular Psychiatry Laboratory, Windeyer Institute of Medical Sciences, Department of Mental Health Sciences, Royal Free and University College London Medical School, 46 Cleveland Street, London W1T 4JF, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S014976340600066
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http://dx.doi.org/10.1016/j.neubiorev.2006.06.022DOI Listing
April 2007

Identification of the Slynar gene (AY070435) and related brain expressed sequences as a candidate gene for susceptibility to affective disorders through allelic and haplotypic association with bipolar disorder on chromosome 12q24.

Am J Psychiatry 2006 Oct;163(10):1767-76

Molecular Psychiatry Laboratory, Windeyer Institute for Medical Science, Department of Psychiatry and Behavioral Sciences, Royal Free and University College Medical School, University College London, 46 Cleveland St., London W1T 4JF, United Kingdom.

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http://dx.doi.org/10.1176/ajp.2006.163.10.1767DOI Listing
October 2006

Estimation of haplotypes at DRD2 may have produced misleading results.

Arch Gen Psychiatry 2006 Aug;63(8):939; author reply 939-40

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http://dx.doi.org/10.1001/archpsyc.63.8.939-aDOI Listing
August 2006

Failure to confirm allelic association between markers at the CAPON gene locus and schizophrenia in a British sample.

Biol Psychiatry 2006 Jan 3;59(2):195-7. Epub 2005 Oct 3.

Molecular Psychiatry Laboratory, Department of Mental Health Sciences, Royal Free and University College London Medical School, Windeyer Institute of Medical Sciences, London, W1T 4JF, UK.

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http://dx.doi.org/10.1016/j.biopsych.2005.08.015DOI Listing
January 2006

Direct genomic PCR sequencing of the high affinity thiamine transporter (SLC19A2) gene identifies three genetic variants in Wernicke Korsakoff syndrome (WKS).

Am J Med Genet B Neuropsychiatr Genet 2005 Aug;137B(1):17-9

Molecular Psychiatry Laboratory, Windeyer Institute of Medical Sciences, Department of Mental Health Sciences, Royal Free and University College London Medical School, 46 Cleveland Street, London W1T 4JF, United Kingdom.

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http://doi.wiley.com/10.1002/ajmg.b.30194
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August 2005

Genetic linkage analysis of the X chromosome in autism, with emphasis on the fragile X region.

Psychiatr Genet 2005 Jun;15(2):83-90

Molecular Psychiatry Laboratory, Department of Psychiatry and Behavioural Sciences, Windeyer Institute of Medical Science, University College London, London.

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June 2005

The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia.

Am J Hum Genet 2005 May 25;76(5):902-7. Epub 2005 Mar 25.

Molecular Psychiatry Laboratory, Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, London, United Kingdom.

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http://dx.doi.org/10.1086/430095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199380PMC
May 2005

Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2.

BMC Genet 2005 Mar 1;6:11. Epub 2005 Mar 1.

Molecular Psychiatry Laboratory, Windeyer Institute for Medical Sciences, Department of Mental Health Sciences, Royal Free and University College London Medical School, 46 Cleveland Street, London, W1T 4JF, UK.

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http://dx.doi.org/10.1186/1471-2156-6-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC554783PMC
March 2005

Mutation screening of X-chromosomal neuroligin genes: no mutations in 196 autism probands.

Am J Med Genet B Neuropsychiatr Genet 2004 Aug;129B(1):82-4

Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/ajmg.b.30069DOI Listing
August 2004

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.

Am J Hum Genet 2003 Jul 11;73(1):49-62. Epub 2003 Jun 11.

Neuropsychiatric Genetics Unit, Department of Genetics, Trinity College, Dublin 2, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180589PMC
http://dx.doi.org/10.1086/376547DOI Listing
July 2003

A novel polymorphism in exon 11 of the WKL1 gene, shows no association with schizophrenia.

Eur J Hum Genet 2002 Aug;10(8):491-4

Molecular Psychiatry Laboratory, University College London, Department of Psychiatry & Behavioural Sciences, Windeyer Institute of Medical Sciences, 46 Cleveland Street, London W1T 4JF, UK.

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http://dx.doi.org/10.1038/sj.ejhg.5200837DOI Listing
August 2002

Linkage disequilibrium and demographic history of the isolated population of the Faroe Islands.

Eur J Hum Genet 2002 Jun;10(6):381-7

Institute for Basic Psychiatric Research, Department of Psychiatric Demography, Psychiatric Hospital in Aarhus, Aarhus University Hospital, Denmark.

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http://dx.doi.org/10.1038/sj.ejhg.5200816DOI Listing
June 2002