Hubert Thierens

Hubert Thierens

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Hubert Thierens

Publications by authors named "Hubert Thierens"

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DNA double strand breaks induced by low dose mammography X-rays in breast tissue: A pilot study.

Authors:
Julie Depuydt Tanguy Viaene Phillip Blondeel Nathalie Roche Rudy Van den Broecke Hubert Thierens Anne Vral

Oncol Lett 2018 Sep 26;16(3):3394-3400. Epub 2018 Jun 26.

Department of Basic Medical Sciences, University of Ghent, 9000 Ghent, Belgium.

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http://www.spandidos-publications.com/10.3892/ol.2018.9024
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http://dx.doi.org/10.3892/ol.2018.9024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096109PMC
September 2018

A new approach for modeling patient overall radiosensitivity and predicting multiple toxicity endpoints for breast cancer patients.

Authors:
Chamberlain Mbah Kim De Ruyck Silke De Schrijver Charlotte De Sutter Kimberly Schiettecatte Chris Monten Leen Paelinck Wilfried De Neve Hubert Thierens Catharine West Gustavo Amorim Olivier Thas Liv Veldeman

Acta Oncol 2018 May 4;57(5):604-612. Epub 2018 Jan 4.

d Department of Radiation Oncology , Ghent University Hospital , Ghent , Belgium.

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http://dx.doi.org/10.1080/0284186X.2017.1417633DOI Listing
May 2018

Screen-detected versus interval cancers: Effect of imaging modality and breast density in the Flemish Breast Cancer Screening Programme.

Authors:
Lore Timmermans Luc Bleyen Klaus Bacher Koen Van Herck Kim Lemmens Chantal Van Ongeval Andre Van Steen Patrick Martens Isabel De Brabander Mathieu Goossens Hubert Thierens

Eur Radiol 2017 Sep 13;27(9):3810-3819. Epub 2017 Mar 13.

Department of Basic Medical Sciences, QCC-Gent, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00330-017-4757-4DOI Listing
September 2017

Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era.

Authors:
David Azria Ariane Lapierre Sophie Gourgou Dirk De Ruysscher Jacques Colinge Philippe Lambin Muriel Brengues Tim Ward Søren M Bentzen Hubert Thierens Tiziana Rancati Christopher J Talbot Ana Vega Sarah L Kerns Christian Nicolaj Andreassen Jenny Chang-Claude Catharine M L West Corey M Gill Barry S Rosenstein

Front Oncol 2017 27;7:83. Epub 2017 Apr 27.

Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.3389/fonc.2017.00083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406456PMC
April 2017

Uncertainty of fast biological radiation dose assessment for emergency response scenarios.

Authors:
Elizabeth A Ainsbury Manuel Higueras Pedro Puig Jochen Einbeck Daniel Samaga Joan Francesc Barquinero Lleonard Barrios Beata Brzozowska Paola Fattibene Eric Gregoire Alicja Jaworska David Lloyd Ursula Oestreicher Horst Romm Kai Rothkamm Laurence Roy Sylwester Sommer Georgia Terzoudi Hubert Thierens Francois Trompier Anne Vral Clemens Woda

Int J Radiat Biol 2017 01 26;93(1):127-135. Epub 2016 Sep 26.

n Helmholtz Zentrum München (HMGU) , Neuherberg , Germany.

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http://dx.doi.org/10.1080/09553002.2016.1227106DOI Listing
January 2017

RENEB intercomparison exercises analyzing micronuclei (Cytokinesis-block Micronucleus Assay).

Authors:
Julie Depuydt Ans Baeyens Stephen Barnard Christina Beinke Anett Benedek Philip Beukes Iwona Buraczewska Firouz Darroudi Stefania De Sanctis Inmaculada Dominguez Octávia Monteiro Gil Valeria Hadjidekova Enikő Kis Ulrike Kulka Florigio Lista Katalin Lumniczky Radhia M'kacher Jayne Moquet Doina Obreja Ursula Oestreicher Jelena Pajic Nuria Pastor Ljubomira Popova Elisa Regalbuto Michelle Ricoul Laure Sabatier Jacobus Slabbert Sylwester Sommer Antonella Testa Hubert Thierens Andrzej Wojcik Anne Vral

Int J Radiat Biol 2017 01 15;93(1):36-47. Epub 2016 Aug 15.

a Faculty of Medicine and Health Sciences , Ghent University , Gent , Belgium.

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http://dx.doi.org/10.1080/09553002.2016.1206231DOI Listing
January 2017

RENEB - Running the European Network of biological dosimetry and physical retrospective dosimetry.

Authors:
Ulrike Kulka Michael Abend Elizabeth Ainsbury Christophe Badie Joan Francesc Barquinero Lleonard Barrios Christina Beinke Emanuela Bortolin Alexandra Cucu Andrea De Amicis Inmaculada Domínguez Paola Fattibene Anne Marie Frøvig Eric Gregoire Kamile Guogyte Valeria Hadjidekova Alicja Jaworska Ralf Kriehuber Carita Lindholm David Lloyd Katalin Lumniczky Fiona Lyng Roberta Meschini Simone Mörtl Sara Della Monaca Octávia Monteiro Gil Alegria Montoro Jayne Moquet Mercedes Moreno Ursula Oestreicher Fabrizio Palitti Gabriel Pantelias Clarice Patrono Laure Piqueret-Stephan Matthias Port María Jesus Prieto Roel Quintens Michelle Ricoul Horst Romm Laurence Roy Géza Sáfrány Laure Sabatier Natividad Sebastià Sylwester Sommer Georgia Terzoudi Antonella Testa Hubert Thierens Istvan Turai François Trompier Marco Valente Pedro Vaz Philippe Voisin Anne Vral Clemens Woda Demetre Zafiropoulos Andrzej Wojcik

Int J Radiat Biol 2017 01 6;93(1):2-14. Epub 2016 Oct 6.

ag Stockholm University, Centre for Radiation Protection Research , Stockholm , Sweden.

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http://dx.doi.org/10.1080/09553002.2016.1230239DOI Listing
January 2017

Investigation of the influence of calibration practices on cytogenetic laboratory performance for dose estimation.

Authors:
François Trompier Marion Baumann Lleonard Barrios Eric Gregoire Michael Abend Elizabeth Ainsbury Stephen Barnard Joan Francesc Barquinero Juan Antonio Bautista Beata Brzozowska Jose Perez-Calatayud Cinzia De Angelis Inmaculada Domínguez Valeria Hadjidekova Ulrike Kulka Juan Carlos Mateos Roberta Meschini Octávia Monteiro Gil Jayne Moquet Ursula Oestreicher Alegria Montoro Pastor Roel Quintens Natividad Sebastià Sylwester Sommer Orlin Stoyanov Hubert Thierens Georgia Terzoudi Juan Ignacio Villaescusa Anne Vral Andrzej Wojcik Demetre Zafiropoulos Laurence Roy

Int J Radiat Biol 2017 01 13;93(1):118-126. Epub 2016 Oct 13.

a Institut de Radioprotection et de Sûreté Nucléaire (IRSN) , Fontenay-aux-roses, France.

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http://dx.doi.org/10.1080/09553002.2016.1213455DOI Listing
January 2017

Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients.

Authors:
Christian Nicolaj Andreassen Barry S Rosenstein Sarah L Kerns Harry Ostrer Dirk De Ruysscher Jamie A Cesaretti Gillian C Barnett Alison M Dunning Leila Dorling Catharine M L West Neil G Burnet Rebecca Elliott Charlotte Coles Emma Hall Laura Fachal Ana Vega Antonio Gómez-Caamaño Christopher J Talbot R Paul Symonds Kim De Ruyck Hubert Thierens Piet Ost Jenny Chang-Claude Petra Seibold Odilia Popanda Marie Overgaard David Dearnaley Matthew R Sydes David Azria Christine Anne Koch Matthew Parliament Michael Blackshaw Michael Sia Maria J Fuentes-Raspall Teresa Ramon Y Cajal Agustin Barnadas Danny Vesprini Sara Gutiérrez-Enríquez Meritxell Mollà Orland Díez John R Yarnold Jens Overgaard Søren M Bentzen Jan Alsner

Radiother Oncol 2016 12 18;121(3):431-439. Epub 2016 Jul 18.

Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark.

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http://dx.doi.org/10.1016/j.radonc.2016.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559879PMC
December 2016

In vitro cellular radiosensitivity in relationship to late normal tissue reactions in breast cancer patients: a multi-endpoint case-control study.

Authors:
Charlot Vandevoorde Julie Depuydt Liv Veldeman Wilfried De Neve Natividad Sebastià Greet Wieme Annelot Baert Sofie De Langhe Jan Philippé Hubert Thierens Anne Vral

Int J Radiat Biol 2016 12 17;92(12):823-836. Epub 2016 Oct 17.

a Ghent University , Department of Basic Medical Sciences , Ghent , Belgium.

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http://dx.doi.org/10.1080/09553002.2016.1230238DOI Listing
December 2016

The role of Size-Specific Dose Estimate (SSDE) in patient-specific organ dose and cancer risk estimation in paediatric chest and abdominopelvic CT examinations.

Authors:
Caro Franck Charlot Vandevoorde Ingeborg Goethals Peter Smeets Eric Achten Koenraad Verstraete Hubert Thierens Klaus Bacher

Eur Radiol 2016 Aug 15;26(8):2646-55. Epub 2015 Dec 15.

Department of Basic Medical Sciences, Ghent University, Proeftuinstraat 86, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00330-015-4091-7DOI Listing
August 2016

Pitfalls in Prediction Modeling for Normal Tissue Toxicity in Radiation Therapy: An Illustration With the Individual Radiation Sensitivity and Mammary Carcinoma Risk Factor Investigation Cohorts.

Authors:
Chamberlain Mbah Hubert Thierens Olivier Thas Jan De Neve Jenny Chang-Claude Petra Seibold Akke Botma Catharine West Kim De Ruyck

Int J Radiat Oncol Biol Phys 2016 08 1;95(5):1466-1476. Epub 2016 Apr 1.

Department of Basic Medical Sciences, Faculty of Health Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2016.03.034DOI Listing
August 2016

A semi‑automated FISH‑based micronucleus‑centromere assay for biomonitoring of hospital workers exposed to low doses of ionizing radiation.

Authors:
Anne Vral Veerle Decorte Julie Depuydt André Wambersie Hubert Thierens

Mol Med Rep 2016 Jul 13;14(1):103-10. Epub 2016 May 13.

Department of Basic Medical Sciences, Ghent University, B‑9000 Ghent, Belgium.

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http://dx.doi.org/10.3892/mmr.2016.5265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918626PMC
July 2016

Novel X-ray imaging technology enables significant patient dose reduction in interventional cardiology while maintaining diagnostic image quality.

Authors:
Liesbeth Eloot Hubert Thierens Yves Taeymans Benny Drieghe Jan De Pooter Sylvie Van Peteghem Dimitri Buytaert Thomas Gijs Régine Lapere Klaus Bacher

Catheter Cardiovasc Interv 2015 Nov 30;86(5):E205-12. Epub 2015 Mar 30.

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1002/ccd.25913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680340PMC
November 2015

Organ Doses and Radiation Risk of Computed Tomographic Coronary Angiography in a Clinical Patient Population: How Do Low-Dose Acquisition Modes Compare?

Authors:
Liesbeth Eloot Daniel Devos Stephen Van Meerbeeck Eric Achten Koenraad Verstraete Hubert Thierens Klaus Bacher

J Comput Assist Tomogr 2015 Jul-Aug;39(4):591-7

From the *Department of Basic Medical Sciences, Ghent University, Ghent, Belgium; and †Department of Radiology, University Hospital Ghent, Ghent, Belgium.

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http://dx.doi.org/10.1097/RCT.0000000000000253DOI Listing
September 2015

Analysis of metal artifact reduction tools for dental hardware in CT scans of the oral cavity: kVp, iterative reconstruction, dual-energy CT, metal artifact reduction software: does it make a difference?

Authors:
An De Crop Jan Casselman Tom Van Hoof Melissa Dierens Elke Vereecke Nicolas Bossu Jaime Pamplona Katharina D'Herde Hubert Thierens Klaus Bacher

Neuroradiology 2015 Aug 1;57(8):841-9. Epub 2015 May 1.

Ghent University, Department of Basic Medical Sciences, Proeftuinstraat 86, B-9000, Gent, Belgium,

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http://link.springer.com/10.1007/s00234-015-1537-1
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http://dx.doi.org/10.1007/s00234-015-1537-1DOI Listing
August 2015

EPI-CT: in vitro assessment of the applicability of the γ-H2AX-foci assay as cellular biomarker for exposure in a multicentre study of children in diagnostic radiology.

Authors:
Charlot Vandevoorde Maria Gomolka Ute Roessler Daniel Samaga Carita Lindholm Marie Fernet Janet Hall Eileen Pernot Houssein El-Saghire Sarah Baatout Ausrele Kesminiene Hubert Thierens

Int J Radiat Biol 2015 Aug 8;91(8):653-63. Epub 2015 Jul 8.

a Ghent University , UGent , Belgium.

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http://dx.doi.org/10.3109/09553002.2015.1047987DOI Listing
August 2015

Correlation of clinical and physical-technical image quality in chest CT: a human cadaver study applied on iterative reconstruction.

Authors:
An De Crop Peter Smeets Tom Van Hoof Merel Vergauwen Tom Dewaele Mathias Van Borsel Eric Achten Koenraad Verstraete Katharina D'Herde Hubert Thierens Klaus Bacher

BMC Med Imaging 2015 Aug 19;15:32. Epub 2015 Aug 19.

Department of Basic Medical Sciences, Ghent University, Proeftuinstraat 86, B-9000, Ghent, Belgium.

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http://dx.doi.org/10.1186/s12880-015-0075-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541737PMC
August 2015

Operational guidance for radiation emergency response organisations in Europe for using biodosimetric tools developed in EU MULTIBIODOSE project.

Authors:
Alicja Jaworska Elizabeth A Ainsbury Paola Fattibene Carita Lindholm Ursula Oestreicher Kai Rothkamm Horst Romm Hubert Thierens Francois Trompier Philippe Voisin Anne Vral Clemens Woda Andrzej Wojcik

Radiat Prot Dosimetry 2015 Apr 1;164(1-2):165-9. Epub 2014 Oct 1.

Centre for Radiation Protection Research, MBW Department, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1093/rpd/ncu294DOI Listing
April 2015

A let-7 microRNA polymorphism in the KRAS 3'-UTR is prognostic in oropharyngeal cancer.

Authors:
Kim De Ruyck Fréderic Duprez Liesbeth Ferdinande Chamberlain Mbah Emmanuel Rios-Velazquez Frank Hoebers Marleen Praet Philippe Deron Katrien Bonte Ernst-Jan Speel Louis Libbrecht Wilfried De Neve Philippe Lambin Hubert Thierens

Cancer Epidemiol 2014 Oct 12;38(5):591-8. Epub 2014 Aug 12.

Department of Basic Medical Sciences, Ghent University, Proeftuinstraat 86, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1016/j.canep.2014.07.008DOI Listing
October 2014

Factors modifying the risk for developing acute skin toxicity after whole-breast intensity modulated radiotherapy.

Authors:
Sofie De Langhe Thomas Mulliez Liv Veldeman Vincent Remouchamps Annick van Greveling Monique Gilsoul Eline De Schepper Kim De Ruyck Wilfried De Neve Hubert Thierens

BMC Cancer 2014 Sep 25;14:711. Epub 2014 Sep 25.

Department of Basic Medical Sciences, Ghent University, Proeftuinstraat 86, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1186/1471-2407-14-711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192342PMC
September 2014

Impact of the digitalisation of mammography on performance parameters and breast dose in the Flemish Breast Cancer Screening Programme.

Authors:
Lore Timmermans An De Hauwere Klaus Bacher Hilde Bosmans Kim Lemmens Luc Bleyen Erik Van Limbergen Patrick Martens Andre Van Steen Griet Mortier Koen Van Herck Hubert Thierens

Eur Radiol 2014 Aug 10;24(8):1808-19. Epub 2014 May 10.

Department of Basic Medical Sciences, QCC-Gent, Ghent University, Ghent, Belgium,

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http://dx.doi.org/10.1007/s00330-014-3169-yDOI Listing
August 2014

Multibiodose radiation emergency triage categorization software.

Authors:
Elizabeth A Ainsbury Stephen Barnard Lleonard Barrios Paola Fattibene Virginie de Gelder Eric Gregoire Carita Lindholm David Lloyd Inger Nergaard Kai Rothkamm Horst Romm Harry Scherthan Hubert Thierens Charlot Vandevoorde Clemens Woda Andrzej Wojcik

Health Phys 2014 Jul;107(1):83-9

*Public Health England Centre for Radiation, Chemical and Environmental Hazards, Chilton, Didcot, Oxford OX11 0RQ; †Universitat Autònoma de Barcelona, Spain; ‡Istituto Superiore di Sanità, Italy; §Universiteit Gent, Belgium; **Institut de radioprotection et de sûreté nucléaire, France; ††Radiation and Nuclear Safety Authority, Finland; ‡‡Bundesamt fuer Strahlenschutz, Germany; §§Inst. für Radiobiologie der Bundeswehr in Verb. mit der Univ. Ulm, Germany; ***Helmholtz Zentrum München, Germany; †††Stockholm University, Sweden.

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http://dx.doi.org/10.1097/HP.0000000000000049DOI Listing
July 2014

Integrated models for the prediction of late genitourinary complaints after high-dose intensity modulated radiotherapy for prostate cancer: making informed decisions.

Authors:
Sofie De Langhe Gert De Meerleer Kim De Ruyck Piet Ost Valérie Fonteyne Wilfried De Neve Hubert Thierens

Radiother Oncol 2014 Jul 17;112(1):95-9. Epub 2014 Jun 17.

Department of Basic Medical Sciences, Ghent University, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2014.04.005DOI Listing
July 2014

Radiogenomics: radiobiology enters the era of big data and team science.

Authors:
Barry S Rosenstein Catharine M West Søren M Bentzen Jan Alsner Christian Nicolaj Andreassen David Azria Gillian C Barnett Michael Baumann Neil Burnet Jenny Chang-Claude Eric Y Chuang Charlotte E Coles Andre Dekker Kim De Ruyck Dirk De Ruysscher Karen Drumea Alison M Dunning Douglas Easton Rosalind Eeles Laura Fachal Sara Gutiérrez-Enríquez Karin Haustermans Luis Alberto Henríquez-Hernández Takashi Imai George D D Jones Sarah L Kerns Zhongxing Liao Kenan Onel Harry Ostrer Matthew Parliament Paul D P Pharoah Timothy R Rebbeck Christopher J Talbot Hubert Thierens Ana Vega John S Witte Philip Wong Frederic Zenhausern

Int J Radiat Oncol Biol Phys 2014 Jul;89(4):709-13

Department of Basic Medical Sciences, Center for Applied Nanobioscience and Medicine, College of Medicine Phoenix, University of Arizona, Phoenix, Arizona.

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http://dx.doi.org/10.1016/j.ijrobp.2014.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119272PMC
July 2014

Intensity modulated radiotherapy induces pro-inflammatory and pro-survival responses in prostate cancer patients.

Authors:
Houssein El-Saghire Charlot Vandevoorde Piet Ost Pieter Monsieurs Arlette Michaux Gert De Meerleer Sarah Baatout Hubert Thierens

Int J Oncol 2014 Apr 17;44(4):1073-83. Epub 2014 Jan 17.

Department of Basic Medical Sciences, Ghent University, Gent, Belgium.

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http://dx.doi.org/10.3892/ijo.2014.2260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977809PMC
April 2014

Inter- and intra-laboratory comparison of a multibiodosimetric approach to triage in a simulated, large scale radiation emergency.

Authors:
Elizabeth A Ainsbury Jenna Al-Hafidh Ainars Bajinskis Stephen Barnard Joan Francesc Barquinero Christina Beinke Virginie de Gelder Eric Gregoire Alicja Jaworska Carita Lindholm David Lloyd Jayne Moquet Reetta Nylund Ursula Oestreicher Sandrine Roch-Lefévre Kai Rothkamm Horst Romm Harry Scherthan Sylwester Sommer Hubert Thierens Charlot Vandevoorde Anne Vral Andrzej Wojcik

Int J Radiat Biol 2014 Feb;90(2):193-202

Public Health England Centre for Radiation, Chemical and Environmental Hazards , Chilton, Didcot, Oxon , UK.

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http://www.tandfonline.com/doi/full/10.3109/09553002.2014.86
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http://dx.doi.org/10.3109/09553002.2014.868616DOI Listing
February 2014

Low doses of ionizing radiation induce immune-stimulatory responses in isolated human primary monocytes.

Authors:
Houssein El-Saghire Arlette Michaux Hubert Thierens Sarah Baatout

Int J Mol Med 2013 Dec 30;32(6):1407-14. Epub 2013 Sep 30.

Radiobiology Unit, Molecular and Cellular Biology, Belgian Nuclear Research Centre (SCK‑CEN), 2400 Mol, Belgium.

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http://dx.doi.org/10.3892/ijmm.2013.1514DOI Listing
December 2013

Three-dimensional rotational X-ray acquisition technique is reducing patients' cancer risk in coronary angiography.

Authors:
Liesbeth Eloot Klaus Bacher Femke Steenbeke Benny Drieghe Peter Gheeraert Yves Taeymans Hubert Thierens

Catheter Cardiovasc Interv 2013 Oct 1;82(4):E419-27. Epub 2013 Jul 1.

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1002/ccd.24879DOI Listing
October 2013

Technical and clinical breast cancer screening performance indicators for computed radiography versus direct digital radiography.

Authors:
Hilde Bosmans An De Hauwere Kim Lemmens Federica Zanca Hubert Thierens Chantal Van Ongeval Koen Van Herck Andre Van Steen Patrick Martens Luc Bleyen Gretel Vande Putte Eliane Kellen Griet Mortier Erik Van Limbergen

Eur Radiol 2013 Oct 21;23(10):2891-8. Epub 2013 May 21.

Department of Radiology, University Hospitals Leuven, Leuven, Belgium,

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http://dx.doi.org/10.1007/s00330-013-2876-0DOI Listing
October 2013

Gene set enrichment analysis highlights different gene expression profiles in whole blood samples X-irradiated with low and high doses.

Authors:
Houssein El-Saghire Hubert Thierens Pieter Monsieurs Arlette Michaux Charlot Vandevoorde Sarah Baatout

Int J Radiat Biol 2013 Aug 16;89(8):628-38. Epub 2013 Apr 16.

Radiobiology Unit, Molecular and Cellular Biology, Belgian Nuclear Research Centre (SCK•CEN), Mol, Belgium.

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http://dx.doi.org/10.3109/09553002.2013.782448DOI Listing
August 2013

Manual versus automated γ-H2AX foci analysis across five European laboratories: can this assay be used for rapid biodosimetry in a large scale radiation accident?

Authors:
Kai Rothkamm Stephen Barnard Elizabeth A Ainsbury Jenna Al-Hafidh Joan-Francesc Barquinero Carita Lindholm Jayne Moquet Marjo Perälä Sandrine Roch-Lefèvre Harry Scherthan Hubert Thierens Anne Vral Veerle Vandersickel

Mutat Res 2013 Aug 3;756(1-2):170-3. Epub 2013 May 3.

Public Health England, Centre for Radiation, Chemical and Environmental Hazards, Chilton, Didcot, Oxon OX11 0RQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2013.04.012DOI Listing
August 2013

Relative biological effectiveness of mammography X-rays at the level of DNA and chromosomes in lymphocytes.

Authors:
Julie Depuydt Annelot Baert Veerle Vandersickel Hubert Thierens Anne Vral

Int J Radiat Biol 2013 Jul 16;89(7):532-8. Epub 2013 Apr 16.

Department of Basic Medical Sciences, University of Ghent, Belgium.

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http://dx.doi.org/10.3109/09553002.2013.782447DOI Listing
July 2013

A predictive model for dysphagia following IMRT for head and neck cancer: introduction of the EMLasso technique.

Authors:
Kim De Ruyck Fréderic Duprez Joke Werbrouck Nick Sabbe De Langhe Sofie Tom Boterberg Indira Madani Olivier Thas De Neve Wilfried Hubert Thierens

Radiother Oncol 2013 Jun 22;107(3):295-9. Epub 2013 Apr 22.

Department of Basic Medical Sciences, Ghent University, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2013.03.021DOI Listing
June 2013

Early biomarkers related to secondary primary cancer risk in radiotherapy treated prostate cancer patients: IMRT versus IMAT.

Authors:
Joke Werbrouck Piet Ost Valerie Fonteyne Gert De Meerleer Wilfried De Neve Evelien Bogaert Laurence Beels Klaus Bacher Anne Vral Hubert Thierens

Radiother Oncol 2013 Jun 19;107(3):377-81. Epub 2013 Jun 19.

Department of Basic Medical Sciences, Ghent University, Gent, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2013.05.014DOI Listing
June 2013

Acute radiation-induced nocturia in prostate cancer patients is associated with pretreatment symptoms, radical prostatectomy, and genetic markers in the TGFβ1 gene.

Authors:
Sofie De Langhe Kim De Ruyck Piet Ost Valérie Fonteyne Joke Werbrouck Gert De Meerleer Wilfried De Neve Hubert Thierens

Int J Radiat Oncol Biol Phys 2013 Feb 2;85(2):393-9. Epub 2012 Jun 2.

Department of Basic Medical Sciences, Ghent University, Gent, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2012.02.061DOI Listing
February 2013

No association between TGF-β1 polymorphisms and radiation-induced lung toxicity in a European cohort of lung cancer patients.

Authors:
An M Voets Cary Oberije Robin B Struijk Bart Reymen Kim De Ruyck Hubert Thierens Katrien Vandecasteele Wilfried De Neve Ruud Houben Dirk De Ruysscher Hubert J M Smeets Philippe Lambin

Radiother Oncol 2012 Dec 3;105(3):296-8. Epub 2012 Nov 3.

Maastricht University, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S01678140120043
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http://dx.doi.org/10.1016/j.radonc.2012.09.016DOI Listing
December 2012

Discrepancies between in silico and in vitro data in the functional analysis of a breast cancer-associated polymorphism in the XRCC6/Ku70 gene.

Authors:
Emanuela Marras Petra Willems Veerle Vandersickel Isabella Ceriani Hubert Thierens Anne Vral Gianpaolo Perletti

Mol Med Rep 2008 Nov-Dec;1(6):805-12

Department of Structural and Functional Biology, Laboratory of Toxicology and Pharmacology, Università degli Studi dell'Insubria, Varese, Italy.

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http://dx.doi.org/10.3892/mmr_00000032DOI Listing
October 2012

Dose-length product of scanners correlates with DNA damage in patients undergoing contrast CT.

Authors:
Laurence Beels Klaus Bacher Peter Smeets Koenraad Verstraete Anne Vral Hubert Thierens

Eur J Radiol 2012 Jul 18;81(7):1495-9. Epub 2011 May 18.

Department of Basic Medical Sciences, Ghent University, Proeftuinstraat 86, 9000 Gent, Belgium.

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http://dx.doi.org/10.1016/j.ejrad.2011.04.063DOI Listing
July 2012

Bioactive porcine matrices in heart valve tissue engineering.

Authors:
Pamela Somers Filip de Somer Maria Cornelissen Hubert Thierens Guido Van Nooten

J Heart Valve Dis 2012 Jul;21(4):535-43

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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July 2012

Epigenetic changes in lymphocytes of solvent-exposed individuals.

Authors:
Lode Godderis Karel De Raedt Ali M Tabish Katrien Poels Nathalie Maertens Kim De Ruyck Simon Bulterys Hubert Thierens Maria K Viaene

Epigenomics 2012 Jun;4(3):269-77

Katholieke Universiteit Leuven, Occupational, Environmental & Insurance Medicine, Kapucijnenvoer 35/5, Leuven, Belgium.

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http://dx.doi.org/10.2217/epi.12.23DOI Listing
June 2012

An optimized growth factor cocktail for ovine mesenchymal stem cells.

Authors:
Pamela Somers Ria Cornelissen Hubert Thierens Guido Van Nooten

Growth Factors 2012 Feb 11;30(1):37-48. Epub 2011 Nov 11.

Department of Basic Medical Sciences, Ghent University, Belgium.

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http://dx.doi.org/10.3109/08977194.2011.634411DOI Listing
February 2012

Decellularization of heart valve matrices: search for the ideal balance.

Authors:
Pamela Somers Filip De Somer Maria Cornelissen Hubert Thierens Guido Van Nooten

Artif Cells Blood Substit Immobil Biotechnol 2012 Feb 22;40(1-2):151-62. Epub 2011 Dec 22.

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.3109/10731199.2011.637925DOI Listing
February 2012

Correlation of contrast-detail analysis and clinical image quality assessment in chest radiography with a human cadaver study.

Authors:
An De Crop Klaus Bacher Tom Van Hoof Peter V Smeets Barbara S Smet Merel Vergauwen Urszula Kiendys Philippe Duyck Koenraad Verstraete Katharina D'Herde Hubert Thierens

Radiology 2012 Jan 4;262(1):298-304. Epub 2011 Nov 4.

Department of Basic Medical Sciences, Ghent University, Proeftuinstraat 86, B-9000 Ghent, Belgium.

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http://pubs.rsna.org/doi/10.1148/radiol.11110447
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January 2012

Development of a multicomponent prediction model for acute esophagitis in lung cancer patients receiving chemoradiotherapy.

Authors:
Kim De Ruyck Nick Sabbe Cary Oberije Katrien Vandecasteele Olivier Thas Dirk De Ruysscher Phillipe Lambin Jan Van Meerbeeck Wilfried De Neve Hubert Thierens

Int J Radiat Oncol Biol Phys 2011 Oct 24;81(2):537-44. Epub 2011 May 24.

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2011.03.012DOI Listing
October 2011

A semi-automated micronucleus-centromere assay to assess low-dose radiation exposure in human lymphocytes.

Authors:
Ans Baeyens Rosemary Swanson Olivia Herd Elizabeth Ainsbury Thulani Mabhengu Pascale Willem Hubert Thierens Jacobus P Slabbert Anne Vral

Int J Radiat Biol 2011 Sep 1;87(9):923-31. Epub 2011 Jun 1.

National Research Foundation - iThemba LABS, Somerset West, South Africa.

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http://dx.doi.org/10.3109/09553002.2011.577508DOI Listing
September 2011

Virtual electron microscopy in cell biology.

Authors:
Sylvia Mione Klaus Bacher Hubert Thierens Maria Cornelissen

Microsc Res Tech 2011 Mar;74(3):251-6

Department of Basic Medical Sciences, Ghent University, De Pintelaan 185, Gent B-9000, Belgium.

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http://doi.wiley.com/10.1002/jemt.20898
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March 2011

Early increase of radiation-induced γH2AX foci in a human Ku70/80 knockdown cell line characterized by an enhanced radiosensitivity.

Authors:
Veerle Vandersickel Julie Depuydt Bram Van Bockstaele Gianpaolo Perletti Jan Philippe Hubert Thierens Anne Vral

J Radiat Res 2010 ;51(6):633-41

Department of Basic Medical Sciences, Ghent University, Gent, Belgium.

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http://dx.doi.org/10.1269/jrr.10033DOI Listing
March 2011

Lack of a correlation between γH2AX foci kinetics in lymphocytes and the severity of acute normal tissue reactions during IMRT treatment for head and neck cancer.

Authors:
Joke Werbrouck Fréderic Duprez Wilfried De Neve Hubert Thierens

Int J Radiat Biol 2011 Jan;87(1):46-56

Department of Basic Medical Sciences, Ghent University, Gent, Belgium.

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http://www.tandfonline.com/doi/full/10.3109/09553002.2010.51
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January 2011

The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure.

Authors:
Anne Vral Michael Fenech Hubert Thierens

Mutagenesis 2011 Jan;26(1):11-7

Department of Basic Medical Sciences, Ghent University, De Pintelaan 185, 9000 Gent, Belgium.

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http://dx.doi.org/10.1093/mutage/geq078DOI Listing
January 2011

Dose response and repair kinetics of gamma-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and gamma-radiation.

Authors:
Laurence Beels Joke Werbrouck Hubert Thierens

Int J Radiat Biol 2010 Sep;86(9):760-8

Department of Basic Medical Sciences, Faculty of Medicine and Health Sciences, Gent, Belgium.

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https://www.tandfonline.com/doi/full/10.3109/09553002.2010.4
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September 2010

Genetic variation in three candidate genes and nicotine dependence, withdrawal and smoking cessation in hospitalized patients.

Authors:
Kim De Ruyck Kristiaan Nackaerts Laurence Beels Joke Werbrouck Annick De Volder Marc Meysman Bihiyga Salhi Jan Van Meerbeeck Hubert Thierens

Pharmacogenomics 2010 Aug;11(8):1053-63

Department of Basic Medical Sciences, Ghent University, Proeftuinstraat 86, Gent, Belgium.

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http://dx.doi.org/10.2217/pgs.10.75DOI Listing
August 2010

Association of TGFbeta1 polymorphisms involved in radiation toxicity with TGFbeta1 secretion in vitro.

Authors:
De Ruyck Kim Beels Laurence Van Meerbeeck Jan De Neve Wilfried Thierens Hubert

Cytokine 2010 Apr 9;50(1):37-41. Epub 2010 Feb 9.

Department of Basic Medical Sciences, Ghent University, Belgium.

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http://dx.doi.org/10.1016/j.cyto.2009.12.013DOI Listing
April 2010

Establishment of a Radiogenomics Consortium.

Authors:
Catharine West Barry S Rosenstein Jan Alsner David Azria Gillian Barnett Adrian Begg Søren Bentzen Neil Burnet Jenny Chang-Claude Eric Chuang Charlotte Coles Kim De Ruyck Dirk De Ruysscher Alison Dunning Rebecca Elliott Laura Fachal Janet Hall Karin Haustermans Carsten Herskind Tobias Hoelscher Takashi Imai Mayumi Iwakawa Don Jones Cecilia Kulich Jan-Hans Langendijk Peter O'Neils Mahmut Ozsahin Matthew Parliament Andrzej Polanski Barry Rosenstein Daniela Seminara Paul Symonds Chris Talbot Hubert Thierens Ana Vega Catherine West John Yarnold

Int J Radiat Oncol Biol Phys 2010 Apr;76(5):1295-6

School of Cancer and Imaging Sciences, The University of Manchester, The Chrisite Hospital, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.ijrobp.2009.12.017DOI Listing
April 2010

The radiosensitizing effect of Ku70/80 knockdown in MCF10A cells irradiated with X-rays and p(66)+Be(40) neutrons.

Authors:
Veerle Vandersickel Monica Mancini Jacobus Slabbert Emanuela Marras Hubert Thierens Gianpaolo Perletti Anne Vral

Radiat Oncol 2010 Apr 27;5:30. Epub 2010 Apr 27.

Department of Structural and Functional Biology, Laboratory of Toxicology and Pharmacology, Università degli Studi dell' Insubria, via A, Da Guissano 10, 21052 Busto Arsizio, Italy.

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http://dx.doi.org/10.1186/1748-717X-5-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877562PMC
April 2010

Prediction of late normal tissue complications in RT treated gynaecological cancer patients: potential of the gamma-H2AX foci assay and association with chromosomal radiosensitivity.

Authors:
Joke Werbrouck Kim De Ruyck Laurence Beels Anne Vral Marc Van Eijkeren Wilfried De Neve Hubert Thierens

Oncol Rep 2010 Feb;23(2):571-8

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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February 2010

Lentivirus-mediated RNA interference of Ku70 to enhance radiosensitivity of human mammary epithelial cells.

Authors:
Veerle Vandersickel Monica Mancini Emanuela Marras Petra Willems Jacobus Slabbert Jan Philippé Ellen Deschepper Hubert Thierens Gianpoalo Perletti Anne Vral

Int J Radiat Biol 2010 Feb;86(2):114-24

Department of Basic Medical Sciences, Ghent University, B-9000Gent, Belgium.

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http://dx.doi.org/10.3109/09553000903419940DOI Listing
February 2010

The micronucleus assay in radiation accidents.

Authors:
Hubert Thierens Anne Vral

Ann Ist Super Sanita 2009 ;45(3):260-4

Department of Basic Medical Sciences, Faculty of Medicine, University of Ghent, Belgium.

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January 2010

Automated micronucleus (MN) scoring for population triage in case of large scale radiation events.

Authors:
Petra Willems Liezel August Jacobus Slabbert Horst Romm Ursula Oestreicher Hubert Thierens Anne Vral

Int J Radiat Biol 2010 Jan;86(1):2-11

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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http://www.tandfonline.com/doi/full/10.3109/0955300090326448
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http://dx.doi.org/10.3109/09553000903264481DOI Listing
January 2010

gamma-H2AX foci as a biomarker for patient X-ray exposure in pediatric cardiac catheterization: are we underestimating radiation risks?

Authors:
Laurence Beels Klaus Bacher Daniël De Wolf Joke Werbrouck Hubert Thierens

Circulation 2009 Nov 26;120(19):1903-9. Epub 2009 Oct 26.

Ghent University, Department of Basic Medical Sciences, Proeftuinstraat 86, 9000 Gent, Belgium.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.109.880385DOI Listing
November 2009

A polymorphism in the promoter region of Ku70/XRCC6, associated with breast cancer risk and oestrogen exposure.

Authors:
Petra Willems Kim De Ruyck Rudy Van den Broecke Amin Makar Gianpaolo Perletti Hubert Thierens Anne Vral

J Cancer Res Clin Oncol 2009 Sep 15;135(9):1159-68. Epub 2009 Feb 15.

Department of Basic Medical Science, Ghent University, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1007/s00432-009-0556-xDOI Listing
September 2009

Typetesting of physical characteristics of digital mammography systems for screening within the Flemish breast cancer screening programme.

Authors:
Hubert Thierens Hilde Bosmans Nico Buls An De Hauwere Klaus Bacher Jurgen Jacobs Peter Clerinx

Eur J Radiol 2009 Jun 18;70(3):539-48. Epub 2008 Apr 18.

Department of Medical Physics and Radiation Protection, QCC, Ghent University, Proeftuinstraat 86, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ejrad.2008.01.046DOI Listing
June 2009

Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes.

Authors:
Joke Werbrouck Kim De Ruyck Fréderic Duprez Liv Veldeman Kathleen Claes Marc Van Eijkeren Tom Boterberg Petra Willems Anne Vral Wilfried De Neve Hubert Thierens

Int J Radiat Oncol Biol Phys 2009 Mar;73(4):1187-95

Department of Basic Medical Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2008.08.073DOI Listing
March 2009

Single-nucleotide polymorphisms in DNA double-strand break repair genes: association with head and neck cancer and interaction with tobacco use and alcohol consumption.

Authors:
Joke Werbrouck Kim De Ruyck Fréderic Duprez Marc Van Eijkeren Ernst Rietzschel Sofie Bekaert Anne Vral Wilfried De Neve Hubert Thierens

Mutat Res 2008 Oct 13;656(1-2):74-81. Epub 2008 Aug 13.

Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University, and Department of Radiation Oncology, Ghent University Hospital, Proeftuinstraat 86, B-9000 Gent, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S138357180800232
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http://dx.doi.org/10.1016/j.mrgentox.2008.07.013DOI Listing
October 2008

In vitro and in vivo evaluation of direct rhenium-188-labeled anti-CD52 monoclonal antibody alemtuzumab for radioimmunotherapy of B-cell chronic lymphocytic leukemia.

Authors:
Mario De Decker Klaus Bacher Hubert Thierens Guido Slegers Rudi A Dierckx Filip De Vos

Nucl Med Biol 2008 Jul;35(5):599-604

Department of Radiopharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.nucmedbio.2008.03.001DOI Listing
July 2008

mBAND analysis of chromosome aberrations in lymphocytes exposed in vitro to alpha-particles and gamma-rays.

Authors:
E Janet Tawn E Janet Caroline A Whitehouse Duncan Holdsworth Kim De Ruyck Katia Vandenbulcke Hubert Thierens

Int J Radiat Biol 2008 Jun;84(6):447-53

Westlakes Research Institute, Moor Row, Cumbria, UK.

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http://dx.doi.org/10.1080/09553000802078412DOI Listing
June 2008

The use of [123I]-2-iodo-L-phenylalanine as an early radiotherapy evaluation tool: in vitro R1M rabdomyosarcoma cell and in vivo mouse experiments.

Authors:
Veerle Kersemans Valentijn Vergote Virginie de Gelder Indira Madani Hubert Thierens Wilfried De Neve John Mertens Guido Slegers Christian Burvenich Kathelijne Peremans Bart De Spiegeleer

Cancer Biother Radiopharm 2008 Apr;23(2):192-201

Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1089/cbr.2007.0362DOI Listing
April 2008

Polymorphisms in nonhomologous end-joining genes associated with breast cancer risk and chromosomal radiosensitivity.

Authors:
Petra Willems Kathleen Claes Ans Baeyens Veerle Vandersickel Joke Werbrouck Kim De Ruyck Bruce Poppe Rudy Van den Broecke Amin Makar Emanuela Marras Gianpaolo Perletti Hubert Thierens Anne Vral

Genes Chromosomes Cancer 2008 Feb;47(2):137-48

Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1002/gcc.20515DOI Listing
February 2008

The characterization and transmissibility of chromosome aberrations induced in peripheral blood lymphocytes by in vitro alpha-particle radiation.

Authors:
E Janet Tawn Caroline A Whitehouse Kim De Ruyck Leanne Hodgson Katia Vandenbulcke Hubert Thierens

Radiat Res 2007 Dec;168(6):666-74

Westlakes Research Institute, Moor Row, Cumbria, United Kingdom.

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http://dx.doi.org/10.1667/RR0969.1DOI Listing
December 2007

Evaluation of uncertainty-based stopping criteria for monte carlo calculations of intensity-modulated radiotherapy and arc therapy patient dose distributions.

Authors:
Barbara Vanderstraeten Ana Maria Luiza Olteanu Nick Reynaert Antonio Leal Wilfried De Neve Hubert Thierens

Int J Radiat Oncol Biol Phys 2007 Oct;69(2):628-37

Department of Medical Physics, Ghent University, Gent, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2007.06.036DOI Listing
October 2007

Predicting risk of radiation-induced lung injury.

Authors:
Indira Madani Kim De Ruyck Hannelore Goeminne Wilfried De Neve Hubert Thierens Jan Van Meerbeeck

J Thorac Oncol 2007 Sep;2(9):864-74

Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1097/JTO.0b013e318145b2c6DOI Listing
September 2007

Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk.

Authors:
Kim De Ruyck Marcin Szaumkessel Isabelle De Rudder Annelore Dehoorne Anne Vral Kathleen Claes Anja Velghe Jan Van Meerbeeck Hubert Thierens

Mutat Res 2007 Jul 21;631(2):101-10. Epub 2007 Apr 21.

Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University, Proeftuinstraat 86, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1016/j.mrgentox.2007.03.010DOI Listing
July 2007

Positron emission tomography-guided, focal-dose escalation using intensity-modulated radiotherapy for head and neck cancer.

Authors:
Indira Madani Wim Duthoy Cristina Derie Werner De Gersem Tom Boterberg Micky Saerens Filip Jacobs Vincent Grégoire Max Lonneux Luc Vakaet Barbara Vanderstraeten Wouter Bauters Katrien Bonte Hubert Thierens Wilfried De Neve

Int J Radiat Oncol Biol Phys 2007 May;68(1):126-35

Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2006.12.070DOI Listing
May 2007

Conversion of CT numbers into tissue parameters for Monte Carlo dose calculations: a multi-centre study.

Authors:
Barbara Vanderstraeten Pik Wai Chin Michael Fix Antonio Leal Grisel Mora Nick Reynaert Joao Seco Martin Soukup Emiliano Spezi Wilfried De Neve Hubert Thierens

Phys Med Biol 2007 Feb 5;52(3):539-62. Epub 2007 Jan 5.

Department of Medical Physics, Ghent University, Gent, Belgium.

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http://dx.doi.org/10.1088/0031-9155/52/3/001DOI Listing
February 2007

Comparison of 6 MV and 18 MV photons for IMRT treatment of lung cancer.

Authors:
Indira Madani Barbara Vanderstraeten Samuel Bral Marc Coghe Werner De Gersem Carlos De Wagter Hubert Thierens Wilfried De Neve

Radiother Oncol 2007 Jan 19;82(1):63-9. Epub 2006 Dec 19.

Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2006.11.016DOI Listing
January 2007

Comparison of dose-volume histograms of IMRT treatment plans for ethmoid sinus cancer computed by advanced treatment planning systems including Monte Carlo.

Authors:
Leen Paelinck Bart De Smedt Nick Reynaert Marc Coghe Werner De Gersem Carlos De Wagter Barbara Vanderstraeten Hubert Thierens Wilfried De Neve

Radiother Oncol 2006 Dec 20;81(3):250-6. Epub 2006 Nov 20.

Department of Radiotherapy and Nuclear Medicine, University Hospital Ghent, Gent, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2006.10.023DOI Listing
December 2006

In vitro radiosensitivity of peripheral blood lymphocytes in multiple sclerosis patients.

Authors:
Ileana Petcu Diana Savu Hubert Thierens Guy Nagels Anne Vral

Int J Radiat Biol 2006 Nov;82(11):793-803

Department of Environmental and Life Physics, National Institute for Physics and Nuclear Engineering Horia Hulubei, Bucharest, Romania.

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http://dx.doi.org/10.1080/09553000600932976DOI Listing
November 2006

Assessment of supra-additive effects of cytotoxic drugs and low dose rate irradiation in an in vitro model for hepatocellular carcinoma.

Authors:
Bieke Lambert Leo De Ridder Filip De Vos Guido Slegers Virginie de Gelder Christophe Van de Wiele Hubert Thierens

Can J Physiol Pharmacol 2006 Oct;84(10):1021-8

Department of Nuclear Medicine, De Pintelaan 185, Ghent University Hospital, 9000 Ghent, Belgium.

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http://www.nrcresearchpress.com/doi/10.1139/y06-055
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http://dx.doi.org/10.1139/y06-055DOI Listing
October 2006

Image quality and radiation dose on digital chest imaging: comparison of amorphous silicon and amorphous selenium flat-panel systems.

Authors:
Klaus Bacher Peter Smeets Ludo Vereecken An De Hauwere Philippe Duyck Robert De Man Koenraad Verstraete Hubert Thierens

AJR Am J Roentgenol 2006 Sep;187(3):630-7

Department of Medical Physics and Radiation Protection, Ghent University, Proeftuinstraat 86, Gent B9000, Belgium.

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http://dx.doi.org/10.2214/AJR.05.0400DOI Listing
September 2006

Accuracy of patient dose calculation for lung IMRT: A comparison of Monte Carlo, convolution/superposition, and pencil beam computations.

Authors:
Barbara Vanderstraeten Nick Reynaert Leen Paelinck Indira Madani Carlos De Wagter Werner De Gersem Wilfried De Neve Hubert Thierens

Med Phys 2006 Sep;33(9):3149-58

Department of Medical Physics, Ghent University, Proeftuinstraat 86, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1118/1.2241992DOI Listing
September 2006

Implementation of biologically conformal radiation therapy (BCRT) in an algorithmic segmentation-based inverse planning approach.

Authors:
Barbara Vanderstraeten Werner De Gersem Wim Duthoy Wilfried De Neve Hubert Thierens

Phys Med Biol 2006 Aug 26;51(16):N277-86. Epub 2006 Jul 26.

Department of Medical Physics, Ghent University, Proeftuinstraat 86, 9000 Gent, Belgium.

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http://dx.doi.org/10.1088/0031-9155/51/16/N02DOI Listing
August 2006

In vitro screening for synergism of high-linear energy transfer 213Bi-radiotherapy with other therapeutic agents for the treatment of B-cell chronic lymphocytic leukemia.

Authors:
Katia Vandenbulcke Hubert Thierens Filip De Vos Jan Philippé Fritz Offner Ann Janssens Christos Apostolidis Alfred Morgenstern Klaus Bacher Virginie de Gelder Rudi A Dierckx Guido Slegers

Cancer Biother Radiopharm 2006 Aug;21(4):364-72

Department of Radiopharmacy, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1089/cbr.2006.21.364DOI Listing
August 2006

TGFbeta1 polymorphisms and late clinical radiosensitivity in patients treated for gynecologic tumors.

Authors:
Kim De Ruyck Marc Van Eijkeren Kathleen Claes Klaus Bacher Anne Vral Wilfried De Neve Hubert Thierens

Int J Radiat Oncol Biol Phys 2006 Jul;65(4):1240-8

Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University, and Department of Radiation Oncology, Gent University Hospital, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2006.03.047DOI Listing
July 2006

Image quality performance of liquid crystal display systems: influence of display resolution, magnification and window settings on contrast-detail detection.

Authors:
Klaus Bacher Peter Smeets An De Hauwere Tony Voet Philippe Duyck Koenraad Verstraete Hubert Thierens

Eur J Radiol 2006 Jun 25;58(3):471-9. Epub 2006 Jan 25.

Department of Medical Physics and Radiation Protection, Ghent University, Proeftuinstraat 86, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1016/j.ejrad.2005.12.016DOI Listing
June 2006

[18F]fluoro-deoxy-glucose positron emission tomography ([18F]FDG-PET) voxel intensity-based intensity-modulated radiation therapy (IMRT) for head and neck cancer.

Authors:
Barbara Vanderstraeten Wim Duthoy Werner De Gersem Wilfried De Neve Hubert Thierens

Radiother Oncol 2006 Jun 29;79(3):249-58. Epub 2006 Mar 29.

Department of Radiotherapy, Ghent University Hospital, Belgium.

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http://dx.doi.org/10.1016/j.radonc.2006.03.003DOI Listing
June 2006

(188)Re-HDD/lipiodol therapy for hepatocellular carcinoma: an activity escalation study.

Authors:
Bieke Lambert Klaus Bacher Luc Defreyne Hans Van Vlierberghe Jae Min Jeong Rong Fu Wang Jan van Meerbeeck Peter Smeets Roberto Troisi Hubert Thierens Filip De Vos Christophe Van de Wiele

Eur J Nucl Med Mol Imaging 2006 Mar 7;33(3):344-52. Epub 2005 Dec 7.

Nuclear Medicine Division, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium.

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http://dx.doi.org/10.1007/s00259-005-1954-1DOI Listing
March 2006

In vivo evaluation and dosimetry of 123I-2-iodo-D-phenylalanine, a new potential tumor-specific tracer for SPECT, in an R1M rhabdomyosarcoma athymic mouse model.

Authors:
Veerle Kersemans Bart Cornelissen Klaus Bacher Ken Kersemans Hubert Thierens Rudi A Dierckx Bart De Spiegeleer Guido Slegers John Mertens

J Nucl Med 2005 Dec;46(12):2104-11

Laboratory for Radiopharmacy, Universiteit Gent, Gent, Belgium.

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December 2005

Pulsatile tinnitus and the intrameatal vascular loop: why do we not hear our carotids?

Authors:
Dirk De Ridder Leo De Ridder Vicky Nowé Hubert Thierens Paul Van de Heyning Aage Møller

Neurosurgery 2005 Dec;57(6):1213-7; discussion 1213-7

Department of Neurosurgery, University Hospital Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1227/01.neu.0000186035.73828.34DOI Listing
December 2005

Chromosomal radiosensitivity of breast cancer with a CHEK2 mutation.

Authors:
Ans Baeyens Kathleen Claes Petra Willems Kim De Ruyck Hubert Thierens Anne Vral

Cancer Genet Cytogenet 2005 Dec;163(2):106-12

Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University, and Center for Medical Genetics, Gent University Hospital, Belgium.

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http://dx.doi.org/10.1016/j.cancergencyto.2005.04.017DOI Listing
December 2005

Effects of estradiol and progesterone on the variability of the micronucleus assay.

Authors:
Ans Baeyens Veerle Vandersickel Hubert Thierens Leo De Ridder Anne Vral

Mutat Res 2005 Oct 11;578(1-2):308-16. Epub 2005 Jul 11.

Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University, L. Pasteurlaan 2, 9000 Gent, Belgium.

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http://dx.doi.org/10.1016/j.mrfmmm.2005.05.013DOI Listing
October 2005

188Re-HDD/lipiodol for treatment of hepatocellular carcinoma: a feasibility study in patients with advanced cirrhosis.

Authors:
Bieke Lambert Klaus Bacher Katrien De Keukeleire Peter Smeets Isabelle Colle Jae Min Jeong Hubert Thierens Roberto Troisi Filip De Vos Christophe Van de Wiele

J Nucl Med 2005 Aug;46(8):1326-32

Nuclear Medicine Division, Ghent University Hospital, Belgium.

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August 2005

Accurate dosimetry: an essential step towards good clinical practice in nuclear medicine.

Authors:
Klaus Bacher Hubert M Thierens

Nucl Med Commun 2005 Jul;26(7):581-6

Department of Medical Physics and Radiation Protection, Ghent University, Belgium.

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http://dx.doi.org/10.1097/01.mnm.0000169204.13754.e2DOI Listing
July 2005

Patient dosimetry in radionuclide therapy: the whys and the wherefores.

Authors:
Hubert M Thierens Myriam A Monsieurs Klaus Bacher

Nucl Med Commun 2005 Jul;26(7):593-9

Department of Medical Physics and Radiation Protection, University of Ghent, Belgium.

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http://dx.doi.org/10.1097/01.mnm.0000167910.76718.adDOI Listing
July 2005

Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: association with single nucleotide polymorphisms in XRCC1, XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes.

Authors:
Kim De Ruyck Marc Van Eijkeren Kathleen Claes Rudy Morthier Anne De Paepe Anne Vral Leo De Ridder Hubert Thierens

Int J Radiat Oncol Biol Phys 2005 Jul;62(4):1140-9

Department of Anatomy, Embryology, Histology and Medical Physics, Ghent University, Proeftuinstraat 86, Gent B-9000, Belgium.

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http://dx.doi.org/10.1016/j.ijrobp.2004.12.027DOI Listing
July 2005

Chromosomal radiosensitivity in breast cancer patients: influence of age of onset of the disease.

Authors:
Ans Baeyens Rudy Van Den Broecke Amin Makar Hubert Thierens Leo De Ridder Anne Vral

Oncol Rep 2005 Feb;13(2):347-53

Department of Anatomy, Embryology, Histology and Medical Physics, University of Ghent, L. Pasteurlaan 2, 9000 Ghent, Belgium.

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February 2005

Patient-specific dose and radiation risk estimation in pediatric cardiac catheterization.

Authors:
Klaus Bacher Evelien Bogaert Régine Lapere Daniël De Wolf Hubert Thierens

Circulation 2005 Jan 20;111(1):83-9. Epub 2004 Dec 20.

Department of Medical Physics and Radiation Protection, Ghent University, Proeftuinstraat 86, B-9000 Gent, Belgium.

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http://dx.doi.org/10.1161/01.CIR.0000151098.52656.3ADOI Listing
January 2005

188Re-HDD/lipiodol therapy for hepatocellular carcinoma: a phase I clinical trial.

Authors:
Bieke Lambert Klaus Bacher Luc Defreyne Filip Gemmel Hans Van Vlierberghe Jae Min Jeong Rudi A Dierckx Christophe Van de Wiele Hubert Thierens Filip De Vos

J Nucl Med 2005 Jan;46(1):60-6

Nuclear Medicine Division, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium.

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January 2005

Biodistribution and dosimetry of (99m)Tc-depreotide (P829) in patients suffering from breast carcinoma.

Authors:
Bieke Van Den Bossche Eveline D'haeninck Klaus Bacher Hubert Thierens Simon Van Belle Rudi Andre Dierckx Christophe Van de Wiele

Cancer Biother Radiopharm 2004 Dec;19(6):776-83

Division of Nuclear Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1089/cbr.2004.19.776DOI Listing
December 2004

Importance of receptor density in alpha radioimmunotherapy in B cell malignancies: an in-vitro study.

Authors:
Katia Vandenbulcke Hubert Thierens Fritz Offner Ann Janssens Virginie de Gelder Klaus Bacher Jan Philippé Filip De Vos Rudi Dierckx Christos Apostolidis Alfred Morgenstern Guido Slegers

Nucl Med Commun 2004 Nov;25(11):1131-6

Department of Radiopharmacy, Ghent University, Belgium.

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http://dx.doi.org/10.1097/00006231-200411000-00011DOI Listing
November 2004

Chromosomal radiosensitivity in secondary-progressive multiple sclerosis patients.

Authors:
Ileana Petcu Diana Savu Anne Vral Hubert Thierens Guy Nagels Leo De Ridder

Int J Radiat Biol 2004 Sep;80(9):663-72

Department of Environmental and Life Physics, National Institute for Physics and Nuclear Engineering Horia Hulubei, 407 Atomistilor St., R-76900 Bucharest-Magurele, Romania.

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http://dx.doi.org/10.1080/09553000400007664DOI Listing
September 2004