Hubert Serve

Hubert Serve

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Hubert Serve

Publications by authors named "Hubert Serve"

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Proteomic Comparison of Malignant Human Germ Cell Tumor Cell Lines.

Dis Markers 2019 3;2019:8298524. Epub 2019 Sep 3.

Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1155/2019/8298524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745167PMC
September 2019

Metabolic Plasticity of Acute Myeloid Leukemia.

Cells 2019 Jul 31;8(8). Epub 2019 Jul 31.

Department of Medicine 2, Hematology/Oncology, Goethe University, 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.3390/cells8080805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721808PMC
July 2019

Functional Dominance of CHIP-Mutated Hematopoietic Stem Cells in Patients Undergoing Autologous Transplantation.

Cell Rep 2019 May;27(7):2022-2028.e3

Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt am Main 60590, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193053
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http://dx.doi.org/10.1016/j.celrep.2019.04.064DOI Listing
May 2019

[Digital Medicine in Oncology: Clinical Decision Support, Real World Data and Patient Involvement].

Dtsch Med Wochenschr 2019 04 29;144(7):430-434. Epub 2019 Mar 29.

Medizinische Klinik 2, Hämatologie/Onkologie, Goethe-Universität Frankfurt.

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0740-8480
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http://dx.doi.org/10.1055/a-0740-8480DOI Listing
April 2019

Clinical and genetic characterization of de novo double-hit B cell precursor leukemia/lymphoma.

Ann Hematol 2019 Mar 6;98(3):647-656. Epub 2019 Jan 6.

Department of Hematology and Oncology, Johann Wolfgang Goethe University of Frankfurt, Theodor Stern Kai 7, 60596, Frankfurt am Main, Germany.

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http://link.springer.com/10.1007/s00277-018-03590-x
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http://dx.doi.org/10.1007/s00277-018-03590-xDOI Listing
March 2019

CMR imaging biosignature of cardiac involvement due to cancer-related treatment by T1 and T2 mapping.

Int J Cardiol 2019 Jan 11;275:179-186. Epub 2018 Oct 11.

Institute of Experimental and Translational Cardiac Imaging, DZHK Centre for Cardiovascular Imaging, Goethe University Hospital Frankfurt, Frankfurt am Main, Germany; Department of Cardiology, Goethe University Hospital Frankfurt, Frankfurt am Main, Germany; Department of Cardiology, Guys and St Thomas' NHS Trust, London, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273183499
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http://dx.doi.org/10.1016/j.ijcard.2018.10.023DOI Listing
January 2019

Loss of DEP-1 (Ptprj) promotes myeloproliferative disease in -ITD acute myeloid leukemia.

Haematologica 2018 11 7;103(11):e505-e509. Epub 2018 Jun 7.

Institute of Molecular Cell Biology, Center for Molecular Biomedicine (CMB), Jena University Hospital

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http://dx.doi.org/10.3324/haematol.2017.185306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278956PMC
November 2018

Bloodstream infections with gram-negative organisms and the impact of multidrug resistance in patients with hematological malignancies.

Ann Hematol 2018 Nov 4;97(11):2225-2234. Epub 2018 Jul 4.

Department of Hematology and Oncology, University Hospital Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00277-018-3423-5DOI Listing
November 2018

Samply.MDR - A Metadata Repository and Its Application in Various Research Networks.

Stud Health Technol Inform 2018 ;253:50-54

Chair of Medical Informatics, Friedrich-Alexander-University Erlangen-Nuernberg, Erlangen, Germany.

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November 2018

Clinical Impact of Colonization with Multidrug-Resistant Organisms on Outcome after Autologous Stem Cell Transplantation: A Retrospective Single-Center Study.

Biol Blood Marrow Transplant 2017 Sep 18;23(9):1455-1462. Epub 2017 May 18.

Department of Hematology and Oncology, Johann Wolfgang Goethe University of Frankfurt, Frankfurt am Main, Germany; University Center for Infectious Diseases, University Hospital Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2017.05.016DOI Listing
September 2017

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation.

N Engl J Med 2017 08 23;377(5):454-464. Epub 2017 Jun 23.

From the Department of Medical Oncology, Dana-Farber Cancer Institute, Boston (R.M.S.); the Division of Biomedical Statistics and Informatics (S.J.M., K.L.) and the Alliance Statistics and Data Center (S.J.M., K.L., S.G.), Mayo Clinic, Rochester, MN; the Alliance Statistics and Data Center, Duke University, Durham, NC (B.L.S.); the Ohio State University Comprehensive Cancer Center, Columbus (S.G., C.D.B., T.W.P., G.M., R.B.K.); Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden (C.T., G.E.), Department of Internal Medicine III, University Hospital of Ulm, Ulm (K.D., R.F.S., H.D.), Hematology and Oncology, University of Leipzig, Leipzig (D.N.), Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover (J.K., A.G.), and Department of Medicine II, Hematology-Oncology, Goethe University Hospital Frankfurt, Frankfurt am Main (H.S.) - all in Germany; the Department of Biomedicine and Prevention, University Tor Vergata, Rome (F.L.-C., S.A.); the Department of Clinical Haematology, Alfred Hospital and Monash University, Melbourne, VIC, Australia (A.W.); Hospital de la Santa Creu i Sant Pau, Hematology Department, Autonomous University of Barcelona, Barcelona (J.S.), and Hospital Universitario la Fe, Hematology Department, Department of Medicine, University of Valencia, Valencia (M.A.S.) - both in Spain; the Department of Medical Oncology and Hematology, Princess Margaret Hospital, Toronto (J.M.B.); Radboud Institute Molecular Studies, Radboud University Medical Center, Nijmegen, the Netherlands (T.W.); the Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle (F.R.A.); the Division of Hematology-Oncology, Stanford Comprehensive Cancer Center, Stanford University, Stanford, CA (B.C.M.); the Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York (M.S.T.); and the Department of Medicine, University of Chicago, Chicago (R.A.L.).

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http://dx.doi.org/10.1056/NEJMoa1614359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754190PMC
August 2017

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia.

Cancer Cell 2017 04;31(4):549-562.e11

Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; Department of Haematology, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK; Cambridge Institute for Medical Research, Wellcome Trust/MRC Stem Cell Institute, Cambridge CB2 0XY, UK; German Cancer Research Center and German Cancer Consortium, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389883PMC
April 2017

RUNX1 cooperates with FLT3-ITD to induce leukemia.

J Exp Med 2017 03 17;214(3):737-752. Epub 2017 Feb 17.

Retroviral Pathogenesis, Heinrich-Pette-Institute, Leibniz Institute for Experimental Virology, 20251 Hamburg, Germany

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http://dx.doi.org/10.1084/jem.20160927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339673PMC
March 2017

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

Ann Surg Oncol 2016 09 8;23(9):2849-57. Epub 2016 Apr 8.

LOEWE Center for Cell and Gene Therapy Frankfurt and Department of Medicine, Hematology/Oncology, Goethe University Hospital Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1245/s10434-016-5218-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972858PMC
September 2016

A high BMI is a risk factor in younger patients with de novo acute myelogenous leukemia.

Eur J Haematol 2016 Jul 17;97(1):17-24. Epub 2015 Sep 17.

Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1111/ejh.12675DOI Listing
July 2016

Mismatched unrelated hematopoietic stem cell transplantation with post-transplant cyclophosphamide for high-risk acute myeloid leukemia.

Ann Hematol 2016 May 8;95(6):1023-5. Epub 2016 Apr 8.

Department of Medicine II, Hematology and Oncology, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00277-016-2652-8DOI Listing
May 2016

Elucidation of tonic and activated B-cell receptor signaling in Burkitt's lymphoma provides insights into regulation of cell survival.

Proc Natl Acad Sci U S A 2016 May 6;113(20):5688-93. Epub 2016 May 6.

Hematology/Oncology, Department of Medicine, Johann Wolfgang Goethe University, 60590 Frankfurt, Germany; Department of Haematology, Cambridge Institute of Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom; German Cancer Consortium/German Cancer Research Center, 69120 Heidelberg, Germany;

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http://dx.doi.org/10.1073/pnas.1601053113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878517PMC
May 2016

STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling.

Nat Commun 2015 Nov 25;6:8928. Epub 2015 Nov 25.

LOEWE Center for Cell and Gene Therapy and Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, Theodor-Stern-Kai 7, Frankfurt 60590, Germany.

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http://dx.doi.org/10.1038/ncomms9928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674773PMC
November 2015

The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

Stem Cell Reports 2015 Oct 10;5(4):633-46. Epub 2015 Sep 10.

Department of Medicine, Hematology/Oncology, Goethe University, 60590 Frankfurt, Germany; German Cancer Consortium, 69120 Heidelberg, Germany; German Cancer Research Center, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624938PMC
October 2015

FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation.

Blood 2015 Mar 20;125(12):1936-47. Epub 2015 Jan 20.

Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt, Germany; German Cancer Consortium, Heidelberg, Germany; German Cancer Research Center, Heidelberg, Germany;

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http://dx.doi.org/10.1182/blood-2014-06-585216DOI Listing
March 2015

Allogeneic stem-cell transplantation in patients with NPM1-mutated acute myeloid leukemia: results from a prospective donor versus no-donor analysis of patients after upfront HLA typing within the SAL-AML 2003 trial.

J Clin Oncol 2015 Feb 29;33(5):403-10. Epub 2014 Dec 29.

Christoph Röllig, Martin Bornhäuser, Michael Kramer, Christian Thiede, Uwe Platzbecker, Martin Wermke, Friedrich Stölzel, Malte von Bonin, Markus Schaich, Johannes Schetelig, and Gerhard Ehninger, Medizinische Klinik und Poliklinik I, Universitätsklinikum der Technischen Universität Dresden; Johannes Schetelig, DKMS, German Bone Marrow Donor Center, Dresden; Anthony D. Ho and Alwin Krämer, Medizinische Universitätsklinik, Abteilung Innere Medizin V, Heidelberg; Kerstin Schäfer-Eckart and Hannes Wandt, 5. Medizinische Klinik, Klinikum Nürnberg, Nürnberg; Mathias Hänel, Klinik für Innere Medizin III, Klinikum Chemnitz, Chemnitz; Hermann Einsele, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg; Walter E. Aulitzky, Robert-Bosch-Krankenhaus, Stuttgart; Norbert Schmitz, Abteilung für Hämatologie, Onkologie und Stammzelltransplantation, ASKLEPIOS Klinik St Georg, Hamburg; Wolfgang E. Berdel, Matthias Stelljes, and Utz Krug, Medizinische Klinik A, Universitätsklinikum Münster, Münster; Carsten Müller-Tidow, Universitätsklinik und Poliklinik für Innere Medizin IV, Universitätsklinikum Halle, Halle (Saale); Claudia D. Baldus, Medizinische Klinik III, Charité-Universitätsmedizin Berlin, Charité Centrum 14, Campus Benjamin Franklin, Berlin; Stefan W. Krause, Medizinische Klinik 5, Universitätsklinikum Erlangen, Erlangen; and Hubert Serve, Medizinische Klinik II, Universitätsklinikum Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1200/JCO.2013.54.4973DOI Listing
February 2015

Quantitative mass spectrometric profiling of cancer-cell proteomes derived from liquid and solid tumors.

J Vis Exp 2015 Feb 27(96):e52435. Epub 2015 Feb 27.

Department of Hematology/Oncology, Goethe University of Frankfurt; German Cancer Consortium; German Cancer Research Center;

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http://dx.doi.org/10.3791/52435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401153PMC
February 2015

Smac mimetic primes apoptosis-resistant acute myeloid leukaemia cells for cytarabine-induced cell death by triggering necroptosis.

Cancer Lett 2014 Mar 30;344(1):101-109. Epub 2013 Oct 30.

Institute for Experimental Cancer Research in Pediatrics, Goethe-University, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2013.10.018DOI Listing
March 2014

Cutting edge: feed-forward activation of phospholipase Cγ2 via C2 domain-mediated binding to SLP65.

J Immunol 2013 Dec 28;191(11):5354-8. Epub 2013 Oct 28.

Institute of Cellular and Molecular Immunology, Georg August University of Göttingen, 37073 Göttingen, Germany;

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http://dx.doi.org/10.4049/jimmunol.1301326DOI Listing
December 2013

Deacetylase inhibitors modulate proliferation and self-renewal properties of leukemic stem and progenitor cells.

Cell Cycle 2012 Sep 16;11(17):3219-26. Epub 2012 Aug 16.

Department of Medicine II, Hematology and Oncology, Johann Wolfgang Goethe-University, Frankfurt/Main, Germany.

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http://dx.doi.org/10.4161/cc.21565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466521PMC
September 2012

Enhanced immune response after a second dose of an AS03-adjuvanted H1N1 influenza A vaccine in patients after hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2011 Oct 13;17(10):1546-50. Epub 2011 Feb 13.

Department of Medicine, Hematology/Oncology, Goethe-University of Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2011.02.004DOI Listing
October 2011

Adaptor protein Lnk binds to PDGF receptor and inhibits PDGF-dependent signaling.

Exp Hematol 2011 May 1;39(5):591-600. Epub 2011 Mar 1.

Department of Medicine, Hematology/Oncology, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.exphem.2011.02.001DOI Listing
May 2011

The deacetylase inhibitor LAQ824 induces notch signalling in haematopoietic progenitor cells.

Leuk Res 2011 Jan 31;35(1):119-25. Epub 2010 Jul 31.

Department of Medicine II, Hematology and Oncology, Goethe Universität Frankfurt, Theodor-Stern-Kai 7, Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.leukres.2010.06.024DOI Listing
January 2011

Adaptor protein Lnk inhibits c-Fms-mediated macrophage function.

J Leukoc Biol 2010 Oct 22;88(4):699-706. Epub 2010 Jun 22.

Department of Hematology and Oncology, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1189/jlb.0309185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218676PMC
October 2010