Huayue Li

Bacillaenes: Decomposition Trigger Point and Biofilm Enhancement in .

Authors:

Huayue Li Xiao Han Yujing Dong Shanshan Xu Chao Chen Yingang Feng Qiu Cui Wenli Li

ACS Omega 2021 Jan 8;6(2):1093-1098. Epub 2021 Jan 8.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

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January 2021

The ubiquitin ligase E6AP facilitates HDAC6-mediated deacetylation and degradation of tumor suppressors.

Authors:

Yanan Zhang Zhida Chen Jing Lin Jie Liu Yahong Lin Huayue Li Yongyi Xi Bo Wei Lihua Ding Qinong Ye

Signal Transduct Target Ther 2020 10 19;5(1):243. Epub 2020 Oct 19.

Department of Medical Molecular Biology, Beijing Institute of Biotechnology, Collaborative Innovation Center for Cancer Medicine, Beijing, 100850, PR China.

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October 2020

Correction to Genetic Manipulation of an Aminotransferase Family Gene Activates Youssoufenes in Marine-derived .

Authors:

Huayue Li Jing Liu Zirong Deng Tong Li Zengzhi Liu Qian Che Wenli Li

Org Lett 2020 Oct 15;22(19):7773. Epub 2020 Sep 15.

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October 2020

An Unusual Type II Polyketide Synthase System Involved in Cinnamoyl Lipid Biosynthesis.

Authors:

Zirong Deng Jing Liu Tong Li Huayue Li Zengzhi Liu Yujing Dong Wenli Li

Angew Chem Int Ed Engl 2021 01 28;60(1):153-158. Epub 2020 Oct 28.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.

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January 2021

Structural Basis of Specificity for Carboxyl-Terminated Acyl Donors in a Bacterial Acyltransferase.

Authors:

Fei Xiao Sheng Dong Yang Liu Yingang Feng Huayue Li Cai-Hong Yun Qiu Cui Wenli Li

J Am Chem Soc 2020 09 1;142(37):16031-16038. Epub 2020 Sep 1.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 266003 Qingdao, China.

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September 2020

Expanding the Structural Diversity of Drimentines by Exploring the Promiscuity of Two N-methyltransferases.

Authors:

Tingting Yao Jing Liu Enjing Jin Zengzhi Liu Huayue Li Qian Che Tianjiao Zhu Dehai Li Wenli Li

iScience 2020 Jul 28;23(7):101323. Epub 2020 Jun 28.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. Electronic address:

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July 2020

Snail promotes the generation of vascular endothelium by breast cancer cells.

Authors:

Zhenyu Chang Yanan Zhang Jie Liu Yiqiong Zheng Huayue Li Yanjun Kong Pengyun Li Haiwen Peng Yajiao Shi Bo Cao Fang Ran Yingjie Chen Yuhua Song Qinong Ye Lihua Ding

Cell Death Dis 2020 06 15;11(6):457. Epub 2020 Jun 15.

Department of Medical Molecular Biology, Beijing Institute of Biotechnology, Collaborative Innovation Center for Cancer Medicine, 100850, Beijing, China.

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June 2020

Targeted isolation of new polycyclic tetramate macrolactams from the deepsea-derived Streptomyces somaliensis SCSIO ZH66.

Authors:

Lukuan Hou Zengzhi Liu Dongqi Yu Huayue Li Jianhua Ju Wenli Li

Bioorg Chem 2020 08 24;101:103954. Epub 2020 May 24.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China. Electronic address:

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August 2020

Genetic Manipulation of an Aminotransferase Family Gene Activates Youssoufenes in Marine-Derived .

Authors:

Huayue Li Jing Liu Zirong Deng Tong Li Zengzhi Liu Qian Che Wenli Li

Org Lett 2020 01 31;22(2):729-733. Epub 2019 Dec 31.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy , Ocean University of China , Qingdao 266003 , China.

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January 2020

An Effective Strategy for Identification of Highly Unstable Bacillaenes.

Authors:

Huayue Li Xiao Han Jun Zhang Yujing Dong Shanshan Xu Yilei Bao Chao Chen Yingang Feng Qiu Cui Wenli Li

J Nat Prod 2019 12 27;82(12):3340-3346. Epub 2019 Nov 27.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy , Ocean University of China , Qingdao 266003 , China.

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December 2019

Antibiotic angucycline derivatives from the deepsea-derived .

Authors:

Lu Yang Lukuan Hou Huayue Li Wenli Li

Nat Prod Res 2020 Dec 5;34(24):3444-3450. Epub 2019 Mar 5.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

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December 2020

Discovery of an Unusual Fatty Acid Amide from the Gene Mutant of Marine-Derived .

Authors:

Jing Hou Jing Liu Lu Yang Zengzhi Liu Huayue Li Qian Che Tianjiao Zhu Dehai Li Wenli Li

Mar Drugs 2018 Dec 28;17(1). Epub 2018 Dec 28.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

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December 2018

Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery.

Authors:

Tingting Yao Jing Liu Zengzhi Liu Tong Li Huayue Li Qian Che Tianjiao Zhu Dehai Li Qianqun Gu Wenli Li

Nat Commun 2018 10 5;9(1):4091. Epub 2018 Oct 5.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, 266003, Qingdao, China.

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October 2018

Staurosporine Derivatives Generated by Pathway Engineering in a Heterologous Host and Their Cytotoxic Selectivity.

Authors:

Fei Xiao Huayue Li Mingyuan Xu Tong Li Ju Wang Chaomin Sun Kui Hong Wenli Li

J Nat Prod 2018 08 14;81(8):1745-1751. Epub 2018 Aug 14.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy , Ocean University of China , Qingdao 266003 , People's Republic of China.

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August 2018

Generation of methylated violapyrones with improved anti-influenza A virus activity by heterologous expression of a type III PKS gene in a marine Streptomyces strain.

Authors:

Lukuan Hou Shuyao Wang Huiming Huang Huayue Li Wei Wang Wenli Li

Bioorg Med Chem Lett 2018 09 18;28(17):2865-2868. Epub 2018 Jul 18.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao 266273, China. Electronic address:

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September 2018

Developing a database for pedestrians' earthquake emergency evacuation in indoor scenarios.

Authors:

Junxue Zhou Sha Li Gaozhong Nie Xiwei Fan Jinxian Tan Huayue Li Xiaoke Pang

PLoS One 2018 20;13(6):e0197964. Epub 2018 Jun 20.

Institute of Geology, China Earthquake Administration, Beijing, China.

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December 2018

Characterization of the biosynthetic gene cluster of the polyene macrolide antibiotic reedsmycins from a marine-derived Streptomyces strain.

Authors:

Tingting Yao Zengzhi Liu Tong Li Hui Zhang Jing Liu Huayue Li Qian Che Tianjiao Zhu Dehai Li Wenli Li

Microb Cell Fact 2018 Jun 19;17(1):98. Epub 2018 Jun 19.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.

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June 2018

Heterologous Expression of a VioA Variant Activates Cryptic Compounds in a Marine-Derived Strain.

Authors:

Xiao Han Lukuan Hou Jing Hou Yongyu Zhang Huayue Li Wenli Li

Mar Drugs 2018 Jun 2;16(6). Epub 2018 Jun 2.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

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June 2018

Exploration of the Glycosyltransferase BmmGT1 from a Marine-Derived Strain as a Potential Enzyme Tool for Compound Glycol-Diversification.

Authors:

Quanquan Liu Pengfei Ren Yang Liu Wen Qin Huayue Li Wenli Li

J Microbiol Biotechnol 2018 Jun;28(6):931-937

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, P.R. China.

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June 2018

Overexpression of a type III PKS gene affording novel violapyrones with enhanced anti-influenza A virus activity.

Authors:

Lukuan Hou Huiming Huang Huayue Li Shuyao Wang Jianhua Ju Wenli Li

Microb Cell Fact 2018 Apr 12;17(1):61. Epub 2018 Apr 12.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.

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April 2018

Discovery of Antimycin-Type Depsipeptides from a Gene Mutant Strain of Deepsea-Derived SCSIO ZH66 and Their Effects on Pro-inflammatory Cytokine Production.

Authors:

Huayue Li Huiming Huang Lukuan Hou Jianhua Ju Wenli Li

Front Microbiol 2017 19;8:678. Epub 2017 Apr 19.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of ChinaQingdao, China.

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April 2017

Two Distinct α-l-Arabinofuranosidases in Caldicellulosiruptor Species Drive Degradation of Arabinose-Based Polysaccharides.

Authors:

Mohammad Abu Saleh Wen-Jie Han Ming Lu Bing Wang Huayue Li Robert M Kelly Fu-Li Li

Appl Environ Microbiol 2017 07 16;83(13). Epub 2017 Jun 16.

Shandong Provincial Key Laboratory of Energy Genetics, Key Laboratory of Biofuel, Qingdao Engineering Laboratory of Single Cell Oil, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, and University of Chinese Academy of Sciences, Beijing, People's Republic of China

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July 2017

A New Dioic Acid from a wbl Gene Mutant of Deepsea-Derived Streptomyces somaliensis SCSIO ZH66.

Authors:

Huiming Huang Huayue Li Yanhong Qiu Lukuan Hou Jianhua Ju Wenli Li

Mar Drugs 2016 Oct 17;14(10). Epub 2016 Oct 17.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

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October 2016

Activation of a plasmid-situated type III PKS gene cluster by deletion of a wbl gene in deepsea-derived Streptomyces somaliensis SCSIO ZH66.

Authors:

Huiming Huang Lukuan Hou Huayue Li Yanhong Qiu Jianhua Ju Wenli Li

Microb Cell Fact 2016 Jun 27;15(1):116. Epub 2016 Jun 27.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.

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June 2016

Stable and biocompatible cystine knot peptides from the marine sponge Asteropus sp.

Authors:

Mingzhi Su Huayue Li Haibo Wang Eun La Kim Hyung Sik Kim Eun-Hee Kim Jaewon Lee Jee H Jung

Bioorg Med Chem 2016 07 6;24(13):2979-2987. Epub 2016 May 6.

College of Pharmacy, Pusan National University, Busan 609-735, Republic of Korea. Electronic address:

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July 2016

Genome-wide identification and characterization of macrolide glycosyltransferases from a marine-derived Bacillus strain and their phylogenetic distribution.

Authors:

Yang Liu Wen Qin Quanquan Liu Jun Zhang Huayue Li Shanshan Xu Pengfei Ren Li Tian Wenli Li

Environ Microbiol 2016 12 8;18(12):4770-4781. Epub 2016 Jun 8.

Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.

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December 2016

Production of disulfide bond-rich peptides by fusion expression using small transmembrane proteins of Escherichia coli.

Authors:

Ziwei Chang Ming Lu Yunqi Ma Dong-Geon Kwag Seo-Hyun Kim Ji-Min Park Bo-Hye Nam Young-Ok Kim Cheul-Min An Huayue Li Jee H Jung Jang-Su Park

Amino Acids 2015 Mar 16;47(3):579-87. Epub 2014 Dec 16.

Department of Chemistry and Chemistry Institute of Functional Materials, Pusan National University, Busan, 609-735, Korea.

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March 2015

Uncovering a glycosyltransferase provides insights into the glycosylation step during macrolactin and bacillaene biosynthesis.

Authors:

Wen Qin Yang Liu Pengfei Ren Jun Zhang Huayue Li Li Tian Wenli Li

Chembiochem 2014 Dec 29;15(18):2747-53. Epub 2014 Oct 29.

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, No. 5 Yushan Road Qingdao, SD 266003 (China).

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December 2014