Publications by authors named "Huali Shen"

45Publications

Quantitative proteomics reveals stage-specific protein regulation of triple negative breast cancer.

Breast Cancer Res Treat 2020 Sep 12. Epub 2020 Sep 12.

Institutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1007/s10549-020-05916-8DOI Listing
September 2020

Fast and precise quantification of serum biomarkers and simultaneous recognition of multiple diseases enabled by a stable isotope-labelled peptides assisted high-throughput MRM strategy.

Analyst 2020 Aug 17;145(15):5299-5306. Epub 2020 Jul 17.

Minhang Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, 201199, China.

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http://dx.doi.org/10.1039/d0an01100bDOI Listing
August 2020

Protein-protein correlations based variable dimension expansion algorithm for high efficient serum biomarker discovery.

Anal Chim Acta 2020 Jul 12;1119:25-34. Epub 2020 Apr 12.

Minhang Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, 201199, China; Department of Systems Biology for Medicine and School of Basic Medical Sciences, Fudan University, Shanghai, China; NHC Key Laboratory of Glycoconjugates Research, Fudan University, Shanghai, 200032, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.aca.2020.04.013DOI Listing
July 2020

Aperture-controllable nano-electrospray emitter and its application in cardiac proteome analysis.

Talanta 2020 Jan 9;207:120340. Epub 2019 Sep 9.

Department of Chemistry and Zhongshan Hospital, Fudan University, Shanghai, 200433, China; Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1016/j.talanta.2019.120340DOI Listing
January 2020

In Situ Synthesis of Magnetic Mesoporous Phenolic Resin for the Selective Enrichment of Glycopeptides.

Anal Chem 2018 06 8;90(12):7357-7363. Epub 2018 Jun 8.

The Fifth People's Hospital of Shanghai and Institutes of Biomedical Sciences , Fudan University , Shanghai 200032 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.analchem.8b00708DOI Listing
June 2018

Study on behaviors and performances of universal N-glycopeptide enrichment methods.

Analyst 2018 Apr;143(8):1870-1880

Department of Chemistry, Fudan University, Shanghai, 200433, P.R. China and Minhang Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, 201199, P.R. China.

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http://dx.doi.org/10.1039/C7AN02062GDOI Listing
April 2018

Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer.

Cell Chem Biol 2018 05 1;25(5):619-633.e5. Epub 2018 Mar 1.

Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Chemistry & Institute of Biomedical Sciences, Fudan University, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2018.01.016DOI Listing
May 2018

A new panel of pancreatic cancer biomarkers discovered using a mass spectrometry-based pipeline.

Br J Cancer 2018 03 13;118(6):e15. Epub 2018 Feb 13.

The Fifth People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.

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http://dx.doi.org/10.1038/bjc.2018.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908675PMC
March 2018

A new panel of pancreatic cancer biomarkers discovered using a mass spectrometry-based pipeline.

Br J Cancer 2017 Dec 9;117(12):1846-1854. Epub 2017 Nov 9.

The Fifth People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.

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http://dx.doi.org/10.1038/bjc.2017.365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729477PMC
December 2017

Facile preparation of 3-D floor-like ordered mesoporous carbon functionalized graphene composites and its application for selective enrichment of N-glycans from human serum.

Talanta 2017 Nov 15;174:689-695. Epub 2017 Jun 15.

Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2017.06.008DOI Listing
November 2017

In-depth proteomic profiling of left ventricular tissues in human end-stage dilated cardiomyopathy.

Oncotarget 2017 Jul;8(29):48321-48332

Institutes of Biomedical Sciences of Shanghai Medical School and Minhang Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.15689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564650PMC
July 2017

Quantitative profiling of glycerophospholipids during mouse and human macrophage differentiation using targeted mass spectrometry.

Sci Rep 2017 03 24;7(1):412. Epub 2017 Mar 24.

Department of Systems Biology for Medicine and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1038/s41598-017-00341-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428309PMC
March 2017

Functional lipidomics: Palmitic acid impairs hepatocellular carcinoma development by modulating membrane fluidity and glucose metabolism.

Hepatology 2017 08 16;66(2):432-448. Epub 2017 Jun 16.

Department of Systems Biology for Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/hep.29033DOI Listing
August 2017

Self-aspiration sampling extractive electrospray ionization mass spectrometry (EESI-MS) for high-throughput analysis of liquid samples.

Rapid Commun Mass Spectrom 2016 08;30 Suppl 1:56-61

Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200433, China.

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http://dx.doi.org/10.1002/rcm.7616DOI Listing
August 2016

Mapping and analyzing the human liver proteome: progress and potential.

Expert Rev Proteomics 2016 09 2;13(9):833-43. Epub 2016 Aug 2.

a Department of Systems Biology for Medicine, School of Basic Medical Sciences , Fudan University , Shanghai , China.

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http://dx.doi.org/10.1080/14789450.2016.1213132DOI Listing
September 2016

Controlling nonspecific trypsin cleavages in LC-MS/MS-based shotgun proteomics using optimized experimental conditions.

Analyst 2015 Nov;140(22):7613-21

Minhang Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, 201199, P. R. China. and Department of Chemistry, Fudan University, Shanghai, 200433, P. R. China.

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http://dx.doi.org/10.1039/c5an01505gDOI Listing
November 2015

Transcriptome and proteome of human hepatocellular carcinoma reveal shared metastatic pathways with significant genes.

Proteomics 2015 Jun 18;15(11):1793-800. Epub 2015 Mar 18.

Department of Systems Biology for Medicine and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, P. R. China.

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http://dx.doi.org/10.1002/pmic.201400275DOI Listing
June 2015

Systematic comparison between SDS-PAGE/RPLC and high-/low-pH RPLC coupled tandem mass spectrometry strategies in a whole proteome analysis.

Analyst 2015 Feb;140(4):1314-22

Department of Chemistry and Institutes of Biomedical Science Shanghai Medical School, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1039/c4an02119cDOI Listing
February 2015

Site-specific structural characterization of O-glycosylation and identification of phosphorylation sites of recombinant osteopontin.

Biochim Biophys Acta 2015 Jun 17;1854(6):581-91. Epub 2014 Oct 17.

Department of Chemistry, Fudan University, Shanghai 200032, PR China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2014.09.025DOI Listing
June 2015

CAV1 promotes HCC cell progression and metastasis through Wnt/β-catenin pathway.

PLoS One 2014 2;9(9):e106451. Epub 2014 Sep 2.

Institutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai, P. R. China; Department of Chemistry, Fudan University, Shanghai, P. R. China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106451PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152279PMC
May 2015

Rapid and sensitive profiling and quantification of the human cell line proteome by LC-MS/MS without prefractionation.

Proteomics 2014 Sep 13;14(17-18):2008-16. Epub 2014 Aug 13.

Department of Chemistry and Institutes of Biomedical Sciences Shanghai Medical School, Fudan University, Shanghai, P. R. China.

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http://dx.doi.org/10.1002/pmic.201300510DOI Listing
September 2014

Efficient and accurate glycopeptide identification pipeline for high-throughput site-specific N-glycosylation analysis.

J Proteome Res 2014 Jun 8;13(6):3121-9. Epub 2014 May 8.

Department of Chemistry, Fudan University , 220 Han Dan Road, Shanghai 200433, P. R. China.

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http://pubs.acs.org/doi/10.1021/pr500238v
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http://dx.doi.org/10.1021/pr500238vDOI Listing
June 2014

A highly parallel microfluidic droplet method enabling single-molecule counting for digital enzyme detection.

Biomicrofluidics 2014 Jan 25;8(1):014110. Epub 2014 Feb 25.

State Key Laboratory of Physical Chemistry of Solid Surfaces, the Key Laboratory for Chemical Biology of Fujian Province, The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, People's Republic of China.

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http://dx.doi.org/10.1063/1.4866766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977795PMC
January 2014

Systematic analysis of missing proteins provides clues to help define all of the protein-coding genes on human chromosome 1.

J Proteome Res 2014 Jan 25;13(1):114-25. Epub 2013 Nov 25.

State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Engineering Research Center for Protein Drugs, National Center for Protein Sciences, Beijing Institute of Radiation Medicine , 27 Taiping Road, Beijing 102206, P. R. China.

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http://dx.doi.org/10.1021/pr400900jDOI Listing
January 2014

Systematic analyses of the transcriptome, translatome, and proteome provide a global view and potential strategy for the C-HPP.

J Proteome Res 2014 Jan 16;13(1):38-49. Epub 2013 Dec 16.

State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Engineering Research Center for Protein Drugs, National Center for Protein Sciences, Beijing Institute of Radiation Medicine , 27 Taiping Road, Beijing 102206, P. R. China.

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http://dx.doi.org/10.1021/pr4009018DOI Listing
January 2014

An iTRAQ based quantitative proteomic strategy to explore novel secreted proteins in metastatic hepatocellular carcinoma cell lines.

Analyst 2013 Aug 10;138(16):4505-11. Epub 2013 Jun 10.

Department of Chemistry and Institutes of Biomedical Sciences of Shanghai Medical School, Fudan University, 138 Yi Xueyuan Road, Shanghai, 200032, PR China.

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http://dx.doi.org/10.1039/c3an00517hDOI Listing
August 2013

Nuclear proteome profile of C57BL/6J mouse liver.

Sci China Life Sci 2013 Jun 5;56(6):513-23. Epub 2013 Jun 5.

School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.

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http://dx.doi.org/10.1007/s11427-013-4488-yDOI Listing
June 2013

A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans.

Elife 2013 May 21;2:e00429. Epub 2013 May 21.

Howard Hughes Medical Institute, University of Colorado, Boulder , Boulder , United States ; Department of Molecular, Cellular and Developmental Biology , University of Colorado, Boulder , Boulder , United States.

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http://dx.doi.org/10.7554/eLife.00429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660743PMC
May 2013

Proteomic study explores AGR2 as pro-metastatic protein in HCC.

Mol Biosyst 2012 Oct;8(10):2710-8

Institutes of Biomedical Sciences, Fudan University, 130 Dong'an Road, Shanghai, P. R. China 200032.

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http://dx.doi.org/10.1039/c2mb25160dDOI Listing
October 2012

Global profiling of proteolytically modified proteins in human metastatic hepatocellular carcinoma cell lines reveals CAPN2 centered network.

Proteomics 2012 Jun;12(12):1917-27

Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, P. R. China.

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http://doi.wiley.com/10.1002/pmic.201200027
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http://dx.doi.org/10.1002/pmic.201200027DOI Listing
June 2012

Regulation of maternal phospholipid composition and IP(3)-dependent embryonic membrane dynamics by a specific fatty acid metabolic event in C. elegans.

Genes Dev 2012 Mar;26(6):554-66

Howard Hughes Medical Institute, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado 80309, USA.

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http://dx.doi.org/10.1101/gad.187054.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315117PMC
March 2012

Systematic proteomic analysis of human hepotacellular carcinoma cells reveals molecular pathways and networks involved in metastasis.

Mol Biosyst 2011 Jun 6;7(6):1908-16. Epub 2011 Apr 6.

Department of Chemistry, Fudan University, Shanghai 200433, China.

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http://dx.doi.org/10.1039/c0mb00265hDOI Listing
June 2011

Comparison of alternative extraction methods for secretome profiling in human hepatocellular carcinoma cells.

Sci China Life Sci 2011 Jan 21;54(1):34-8. Epub 2011 Jan 21.

Institutes of Biomedical Sciences and Department of Chemistry, Fudan University, Shanghai, 200032, China.

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http://link.springer.com/content/pdf/10.1007/s11427-010-4122
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http://link.springer.com/10.1007/s11427-010-4122-1
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http://dx.doi.org/10.1007/s11427-010-4122-1DOI Listing
January 2011

Nanozeolite-driven approach for enrichment of secretory proteins in human hepatocellular carcinoma cells.

Proteomics 2009 Nov;9(21):4881-8

Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai, PR China.

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http://dx.doi.org/10.1002/pmic.200800877DOI Listing
November 2009

[Sample pre-processing for mass spectrometric analysis of glycoprotein structure].

Se Pu 2007 Sep;25(5):623-7

Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.

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September 2007

Analysis of nuclear proteome in C57 mouse liver tissue by a nano-flow 2-D-LC-ESI-MS/MS approach.

J Sep Sci 2006 Nov;29(17):2635-46

Department of Chemistry, Research Center for Proteome, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/jssc.200600065DOI Listing
November 2006