Huafeng Zhang

Huafeng Zhang

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Serum Phosphorylated Neurofilament Heavy Subunit-H, a Potential Predictive Biomarker for Postoperative Cognitive Dysfunction in Elderly Subjects Undergoing Hip Joint Arthroplasty.

J Arthroplasty 2019 Aug 4;34(8):1602-1605. Epub 2019 Apr 4.

Department of anesthesiology, HwaMei Hospital, University of Chinese Academy of Sciences (Ningbo No.2 Hospital), Ningbo City, Zhejiang Province, China.

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http://dx.doi.org/10.1016/j.arth.2019.03.073DOI Listing
August 2019

Hypoxia and Metabolism in Metastasis.

Adv Exp Med Biol 2019 ;1136:87-95

Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, China.

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http://dx.doi.org/10.1007/978-3-030-12734-3_6DOI Listing
August 2019

Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.

EMBO Rep 2019 Aug 5:e48115. Epub 2019 Aug 5.

Anhui Key Laboratory of Hepatopancreatobiliary Surgery, Department of General Surgery, Anhui Provincial Hospital, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, China.

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http://dx.doi.org/10.15252/embr.201948115DOI Listing
August 2019

Hypoxia-reprogrammed tricarboxylic acid cycle promotes the growth of human breast tumorigenic cells.

Oncogene 2019 Aug 13. Epub 2019 Aug 13.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

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http://dx.doi.org/10.1038/s41388-019-0932-1DOI Listing
August 2019

Capital assets framework for analyzing household vulnerability during disaster.

Disasters 2019 Jul 23. Epub 2019 Jul 23.

The Fafo Institute for Labour and Social Research.

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http://dx.doi.org/10.1111/disa.12393DOI Listing
July 2019

Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells.

Cell Metab 2019 Apr 6;29(4):979-992.e4. Epub 2018 Dec 6.

Guangzhou First People's Hospital, School of Medicine and Institutes for Life Sciences, South China University of Technology, Guangzhou 510006, China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, China; Division of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei 230027, China; Key Laboratory of Biomedical Engineering of Guangdong Province, South China University of Technology, Guangzhou 510006, China; Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education, South China University of Technology, Guangzhou 510006, China; Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou 510005, China. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.11.007DOI Listing
April 2019

, a Dehydrin Gene from Pepper, Plays an Important Role in Salt and Osmotic Stress Responses.

Int J Mol Sci 2019 Apr 23;20(8). Epub 2019 Apr 23.

College of Horticulture, Northwest A&F University, Yangling 712100, China.

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http://dx.doi.org/10.3390/ijms20081989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514665PMC
April 2019

CaMADS, a MADS-box transcription factor from pepper, plays an important role in the response to cold, salt, and osmotic stress.

Plant Sci 2019 Mar 1;280:164-174. Epub 2018 Dec 1.

College of Horticulture, Northwest A&F University, Yangling, Shaanxi, 712100, China.

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http://dx.doi.org/10.1016/j.plantsci.2018.11.020DOI Listing
March 2019

Knockdown of lncRNA BDNF-AS suppresses neuronal cell apoptosis via downregulating miR-130b-5p target gene PRDM5 in acute spinal cord injury.

RNA Biol 2018 10;15(8):1071-1080. Epub 2018 Sep 10.

a Department of Orthopedics , The First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan Province , China.

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http://dx.doi.org/10.1080/15476286.2018.1493333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161672PMC
November 2018

Circulating Tumor Microparticles Promote Lung Metastasis by Reprogramming Inflammatory and Mechanical Niches via a Macrophage-Dependent Pathway.

Cancer Immunol Res 2018 09 12;6(9):1046-1056. Epub 2018 Jul 12.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0574DOI Listing
September 2018

Mechanisms by Which Dendritic Cells Present Tumor Microparticle Antigens to CD8 T Cells.

Cancer Immunol Res 2018 09 17;6(9):1057-1068. Epub 2018 Jul 17.

Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0716DOI Listing
September 2018

Morin protects glucocorticoid-induced osteoporosis through regulating the mitogen-activated protein kinase signaling pathway.

J Nat Med 2018 Sep 24;72(4):929-936. Epub 2018 Jul 24.

The Department of Orthopedics, Tianjin Medical University Metabolic Disease Hospital, Heping District, Tianjin, China.

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http://dx.doi.org/10.1007/s11418-018-1228-4DOI Listing
September 2018

LncRNA DGCR5 suppresses neuronal apoptosis to improve acute spinal cord injury through targeting PRDM5.

Cell Cycle 2018 11;17(16):1992-2000. Epub 2018 Sep 11.

a Department of Orthopedics , the First Affiliated Hospital of Zhengzhou University , Zhengzhou , China.

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http://dx.doi.org/10.1080/15384101.2018.1509622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224267PMC
September 2018

Metabolic reprogramming for cancer cells and their microenvironment: Beyond the Warburg Effect.

Biochim Biophys Acta Rev Cancer 2018 08 28;1870(1):51-66. Epub 2018 Jun 28.

Laboratory of Cancer and Stem Cell metabolism, Guangzhou First Hospital, School of Medicine, South China University of Technology, Guangzhou 510006, China; CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei 230027, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2018.06.005DOI Listing
August 2018

Autosomal dominant retinitis pigmentosa-associated gene PRPF8 is essential for hypoxia-induced mitophagy through regulating ULK1 mRNA splicing.

Autophagy 2018 13;14(10):1818-1830. Epub 2018 Aug 13.

a State Key Laboratory of Proteomics, Institute of Basic Medical Sciences , National Center of Biomedical Analysis , Beijing , China.

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http://dx.doi.org/10.1080/15548627.2018.1501251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135625PMC
August 2018

Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program.

Cancer Res 2018 07 15;78(14):3926-3937. Epub 2018 May 15.

National Key Laboratory of Medical Molecular Biology and Department of Immunology, Institute of Basic Medical Sciences, Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, China.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-17-3719DOI Listing
July 2018

Publisher Correction: Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.

Nat Commun 2018 05 1;9(1):1808. Epub 2018 May 1.

Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 100005, Beijing, China.

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http://www.nature.com/articles/s41467-018-04169-w
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http://dx.doi.org/10.1038/s41467-018-04169-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931583PMC
May 2018

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.

EMBO Mol Med 2018 04;10(4)

Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease, CAS Center for Excellence in Molecular Cell Sciences, Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei, China

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http://embomolmed.embopress.org/lookup/doi/10.15252/emmm.201
Publisher Site
http://dx.doi.org/10.15252/emmm.201708689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887903PMC
April 2018

Tumor-Repopulating Cells Induce PD-1 Expression in CD8 T Cells by Transferring Kynurenine and AhR Activation.

Cancer Cell 2018 03;33(3):480-494.e7

Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing 100005, China; Clinical Immunology Center, CAMS, Beijing 100005, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.02.005DOI Listing
March 2018

IL6 blockade potentiates the anti-tumor effects of γ-secretase inhibitors in Notch3-expressing breast cancer.

Cell Death Differ 2018 02 13;25(2):330-339. Epub 2017 Oct 13.

Key Laboratory of Breast Cancer in Shanghai, Cancer Institute, Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China.

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http://dx.doi.org/10.1038/cdd.2017.162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762847PMC
February 2018

Alkaline phosphatase-triggered assembly of etoposide enhances its anticancer effect.

Chem Commun (Camb) 2018 Feb;54(15):1853-1856

CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China.

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http://dx.doi.org/10.1039/c7cc09365aDOI Listing
February 2018

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.

Nat Commun 2018 02 28;9(1):873. Epub 2018 Feb 28.

Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, 100005, China.

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http://dx.doi.org/10.1038/s41467-018-03225-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830447PMC
February 2018

A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8 T cells.

Nat Cell Biol 2018 01 11;20(1):21-27. Epub 2017 Dec 11.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1038/s41556-017-0002-2DOI Listing
January 2018

CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.

Oncotarget 2017 Dec 7;8(69):114328-114343. Epub 2017 Dec 7.

Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

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http://dx.doi.org/10.18632/oncotarget.23107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768407PMC
December 2017

[Application of modified adjustable skin stretching and secure wound-closure system in repairing of skin and soft tissue defect].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 12;31(12):1481-1484

The Third Department of Surgery, Zhengzhou Renji Hospital, Zhengzhou Henan, 450000, P.R.China.

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http://dx.doi.org/10.7507/1002-1892.201707103DOI Listing
December 2017

Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway.

Nat Commun 2017 11 15;8(1):1506. Epub 2017 Nov 15.

Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Sciences, University of Science and Technology of China, Hefei, 230027, China.

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http://dx.doi.org/10.1038/s41467-017-01647-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686148PMC
November 2017

A 53-year-old man with a sclerosing rib lesion: A case report.

Medicine (Baltimore) 2017 Nov;96(47):e8692

Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1097/MD.0000000000008692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708949PMC
November 2017

[Application of shortened replantation combined with limb lengthening in treatment of severe amputation of middle and distal lower leg].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 08;31(8):936-940

Department of Trauma Orthopedics, Zhengzhou Renji Hospital, Zhengzhou Henan, 450000, P.R.China.

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http://dx.doi.org/10.7507/1002-1892.201703069DOI Listing
August 2017

Bioluminescence Sensing of γ-Glutamyltranspeptidase Activity In Vitro and In Vivo.

Anal Chem 2017 07 20;89(13):7017-7021. Epub 2017 Jun 20.

CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China , Hefei, Anhui 230026, China.

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http://dx.doi.org/10.1021/acs.analchem.7b00567DOI Listing
July 2017

CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.

EMBO Rep 2017 05 21;18(5):809-825. Epub 2017 Mar 21.

Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Sciences, University of Science and Technology of China, Hefei, China

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http://dx.doi.org/10.15252/embr.201643617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412808PMC
May 2017

Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.

EMBO J 2017 05 4;36(10):1330-1347. Epub 2017 Apr 4.

CAS Key Laboratory of Innate Immunity and Chronic Disease, Hefei National Laboratory for Physical Sciences at Microscale, Innovation Center for Cell Signaling Network, School of Life Science, University of Science and Technology of China, Hefei, China

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http://dx.doi.org/10.15252/embj.201695417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430220PMC
May 2017

Menin enhances c-Myc-mediated transcription to promote cancer progression.

Nat Commun 2017 05 5;8:15278. Epub 2017 May 5.

CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Science, University of Science and Technology of China, Hefei, Anhui 230027, China.

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http://dx.doi.org/10.1038/ncomms15278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424160PMC
May 2017

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells.

Nat Commun 2017 05 10;8:15207. Epub 2017 May 10.

National Key Laboratory of Medical Molecular Biology &Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China.

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http://dx.doi.org/10.1038/ncomms15207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436221PMC
May 2017

Microparticles mediate human papillomavirus type 6 or 11 infection of human macrophages.

Cell Mol Immunol 2017 04 20;14(4):395-397. Epub 2015 Apr 20.

State Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1038/cmi.2015.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380938PMC
April 2017

Adenosine effectively restores endotoxin-induced inhibition of human neutrophil chemotaxis via A1 receptor-p38 pathway.

Inflamm Res 2017 Apr 10;66(4):353-364. Epub 2017 Jan 10.

Department of Burn and Plastic Surgery, Affiliated Hospital, Jiangsu University, Zhenjiang, Jiangsu, China.

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http://dx.doi.org/10.1007/s00011-016-1021-3DOI Listing
April 2017

Endotoxin-induced autocrine ATP signaling inhibits neutrophil chemotaxis through enhancing myosin light chain phosphorylation.

Proc Natl Acad Sci U S A 2017 04 10;114(17):4483-4488. Epub 2017 Apr 10.

Department of Burn and Plastic Surgery, Affiliated Hospital, Jiangsu University, Zhenjiang 212001, Jiangsu Province, China;

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http://dx.doi.org/10.1073/pnas.1616752114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410827PMC
April 2017

Pleiotropic regulations of neutrophil receptors response to sepsis.

Inflamm Res 2017 Mar 30;66(3):197-207. Epub 2016 Sep 30.

Department of Burns and Plastic Surgery, Affiliated Hospital, Jiangsu University, Zhenjiang, 212001, Jiangsu, China.

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http://dx.doi.org/10.1007/s00011-016-0993-3DOI Listing
March 2017

Pre-instillation of tumor microparticles enhances intravesical chemotherapy of nonmuscle-invasive bladder cancer through a lysosomal pathway.

Biomaterials 2017 01 24;113:93-104. Epub 2016 Oct 24.

National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.10.036DOI Listing
January 2017

Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.

Oncoimmunology 2017 19;6(3):e1282589. Epub 2017 Jan 19.

Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China; Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, China.

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http://dx.doi.org/10.1080/2162402X.2017.1282589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384362PMC
January 2017

Endotoxin promotes neutrophil hierarchical chemotaxis via the p38-membrane receptor pathway.

Oncotarget 2016 Nov;7(45):74247-74258

Department of Burn and Plastic Surgery, Affiliated Hospital, Jiangsu University, Zhenjiang, Jiangsu Province, China.

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http://dx.doi.org/10.18632/oncotarget.12093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342050PMC
November 2016

Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.

Cell Res 2016 Oct 20;26(10):1112-1130. Epub 2016 Sep 20.

CAS Key laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Science, Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei, Anhui 230027, China.

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http://dx.doi.org/10.1038/cr.2016.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113304PMC
October 2016

Hydrazide d-luciferin for in vitro selective detection and intratumoral imaging of Cu(2.).

Biosens Bioelectron 2016 Sep 22;83:200-4. Epub 2016 Apr 22.

CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2016.04.067DOI Listing
September 2016

Intracellular Self-Assembly of Cyclic d-Luciferin Nanoparticles for Persistent Bioluminescence Imaging of Fatty Acid Amide Hydrolase.

ACS Nano 2016 07 29;10(7):7147-53. Epub 2016 Jun 29.

CAS Key Laboratory of Soft Matter Chemistry, Hefei Science Center CAS, Department of Chemistry, University of Science and Technology of China , 96 Jinzhai Road, Hefei, Anhui 230026, China.

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http://dx.doi.org/10.1021/acsnano.6b03412DOI Listing
July 2016

Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles.

Cell Res 2016 06 10;26(6):713-27. Epub 2016 May 10.

National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China.

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http://dx.doi.org/10.1038/cr.2016.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897183PMC
June 2016

HIF-1 suppresses lipid catabolism to promote cancer progression.

Authors:
Huafeng Zhang

Mol Cell Oncol 2015 Oct-Dec;2(4):e980184. Epub 2015 Jul 7.

CAS Key Laboratory of Innate Immunity and Chronic Disease; School of Life Sciences ; University of Science and Technology of China ; Hefei, China.

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http://dx.doi.org/10.4161/23723556.2014.980184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905416PMC
June 2016

Inequity in level of healthcare utilization before and after universal health coverage reforms in China: evidence from household surveys in Sichuan Province.

Int J Equity Health 2016 Jun 22;15:96. Epub 2016 Jun 22.

Fafo Research Foundation, PO Box 2947, Tøyen, NO-0608, Oslo, Norway.

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http://dx.doi.org/10.1186/s12939-016-0385-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917991PMC
June 2016

Delivery of oncolytic adenovirus into the nucleus of tumorigenic cells by tumor microparticles for virotherapy.

Biomaterials 2016 May 23;89:56-66. Epub 2016 Feb 23.

National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, 100005, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430030, China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.02.025DOI Listing
May 2016

Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression.

Oncoimmunology 2016 Apr 18;5(4):e1118599. Epub 2016 Feb 18.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; State Key Laboratory of Medical Molecular Biology and Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1080/2162402X.2015.1118599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839324PMC
April 2016

Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression.

Cell Mol Life Sci 2016 Jan 23;73(2):377-92. Epub 2015 Oct 23.

Hefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, 230027, China.

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http://dx.doi.org/10.1007/s00018-015-2070-4DOI Listing
January 2016

Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma.

Oncotarget 2016 Jan;7(3):3267-82

The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, China.

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http://dx.doi.org/10.18632/oncotarget.6572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823105PMC
January 2016

Efficient extravasation of tumor-repopulating cells depends on cell deformability.

Sci Rep 2016 Jan 20;6:19304. Epub 2016 Jan 20.

Laboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, School of Life Sciences, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.

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http://dx.doi.org/10.1038/srep19304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726408PMC
January 2016

Analysis for clinical effect of virtual windowing and poking reduction treatment for Schatzker III tibial plateau fracture based on 3D CT data.

Biomed Res Int 2015 12;2015:231820. Epub 2015 Feb 12.

Department of Orthopedics, Tianjin Medical University General Hospital, No. 154 Anshan Road, Tianjin 300052, China ; Tianjin Hospital, No. 406 South JieFang Road, Tianjin 300210, China.

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http://dx.doi.org/10.1155/2015/231820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341848PMC
November 2015

Brief Report: Human Mesenchymal Stem-Like Cells Facilitate Floating Tumorigenic Cell Growth via Glutamine-Ammonium Cycle.

Stem Cells 2015 Sep 23;33(9):2877-84. Epub 2015 Jun 23.

State Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.

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http://dx.doi.org/10.1002/stem.2076DOI Listing
September 2015

Lipid mediator lipoxin A4 inhibits tumor growth by targeting IL-10-producing regulatory B (Breg) cells.

Cancer Lett 2015 Aug 12;364(2):118-24. Epub 2015 May 12.

Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China; State Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.04.030DOI Listing
August 2015

Intracellular Self-Assembly of Taxol Nanoparticles for Overcoming Multidrug Resistance.

Angew Chem Int Ed Engl 2015 Aug 26;54(33):9700-4. Epub 2015 Jun 26.

CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026 (China) http://lianglab.ustc.edu.cn.

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http://dx.doi.org/10.1002/anie.201504329DOI Listing
August 2015

Tumor cell-derived microparticles: a new form of cancer vaccine.

Oncoimmunology 2015 Aug 27;4(8):e1017704. Epub 2015 May 27.

State Key Laboratory of Medical Molecular Biology & Department of Immunology; Institute of Basic Medical Sciences; Chinese Academy of Medical Sciences & Peking Union Medical College ; Beijing, China.

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http://dx.doi.org/10.1080/2162402X.2015.1017704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570097PMC
August 2015

Influenza virus aggravates the ox-LDL-induced apoptosis of human endothelial cells via promoting p53 signaling.

J Med Virol 2015 Jul 16;87(7):1113-23. Epub 2015 Mar 16.

Department of Obstetrics and Gynecology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.

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http://doi.wiley.com/10.1002/jmv.24166
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July 2015

Human fibroblast reprogramming to pluripotent stem cells regulated by the miR19a/b-PTEN axis.

PLoS One 2014 16;9(4):e95213. Epub 2014 Apr 16.

Innovation Center for Cell Biology, School of Life Science, University of Science and Technology of China, Hefei, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095213PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989277PMC
June 2015

Analysis of hypoxia-induced metabolic reprogramming.

Methods Enzymol 2014 ;542:425-55

Vascular Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Departments of Pediatrics, Medicine, Oncology, Radiation Oncology, and Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-416618-9.00022-4DOI Listing
May 2015

Upregulation of cytosolic phosphoenolpyruvate carboxykinase is a critical metabolic event in melanoma cells that repopulate tumors.

Cancer Res 2015 Apr 24;75(7):1191-6. Epub 2015 Feb 24.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. State Key Laboratory of Medical Molecular Biology and Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629827PMC
April 2015

cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.

Cell Res 2015 Apr 20;25(4):429-44. Epub 2015 Mar 20.

CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Science, University of Science and Technology of China, Hefei, Anhui 230027, China.

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http://www.nature.com/articles/cr201533
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http://dx.doi.org/10.1038/cr.2015.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387561PMC
April 2015

miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency.

EMBO J 2015 Mar 20;34(5):609-23. Epub 2015 Jan 20.

The CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Biology, School of Life Sciences, University of Science and Technology of China, Hefei, China

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http://dx.doi.org/10.15252/embj.201490441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365031PMC
March 2015

Cell-free tumor microparticle vaccines stimulate dendritic cells via cGAS/STING signaling.

Cancer Immunol Res 2015 Feb 4;3(2):196-205. Epub 2014 Dec 4.

State Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0177DOI Listing
February 2015

LASP1 is a HIF1α target gene critical for metastasis of pancreatic cancer.

Cancer Res 2015 Jan 10;75(1):111-9. Epub 2014 Nov 10.

Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. Department of Pancreatic Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286473PMC
January 2015

Controlled intracellular self-assembly and disassembly of 19F nanoparticles for MR imaging of caspase 3/7 in zebrafish.

ACS Nano 2015 Jan 30;9(1):761-8. Epub 2014 Dec 30.

CAS Key Laboratory of Soft Matter Chemistry, University of Science and Technology of China , 96 Jinzhai Road, Hefei, Anhui 230026, China.

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http://dx.doi.org/10.1021/nn5062657DOI Listing
January 2015

Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor.

Nat Commun 2015 Jan 23;6:5988. Epub 2015 Jan 23.

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China and Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100190, China.

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http://dx.doi.org/10.1038/ncomms6988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354030PMC
January 2015

Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.

Nat Commun 2014 Oct 10;5:5212. Epub 2014 Oct 10.

Institute for Cancer Research and CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Biology, School of Life Science, University of Science and Technology of China, Hefei 230027, China.

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http://dx.doi.org/10.1038/ncomms6212DOI Listing
October 2014

HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.

Cell Rep 2014 Sep 18;8(6):1930-1942. Epub 2014 Sep 18.

Institute for Cancer Research and CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Biology, School of Life Science, University of Science and Technology of China, Hefei 230027, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.08.028DOI Listing
September 2014

Switch of glycolysis to gluconeogenesis by dexamethasone for treatment of hepatocarcinoma.

Nat Commun 2013 ;4:2508

1] Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China [2].

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http://dx.doi.org/10.1038/ncomms3508DOI Listing
May 2014

Hypoxia and cancer cell metabolism.

Acta Biochim Biophys Sin (Shanghai) 2014 Mar 3;46(3):214-9. Epub 2014 Jan 3.

Innovation Center for Cell Biology, School of Life Science, University of Science and Technology of China, Hefei 230027, China.

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http://dx.doi.org/10.1093/abbs/gmt148DOI Listing
March 2014

Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect.

Mol Cell 2014 Jan 5;53(1):88-100. Epub 2013 Dec 5.

Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2013.11.004DOI Listing
January 2014

[Alcohol dependence mediated by monoamine neurotransmitters in the central nervous system].

Yi Chuan 2014 Jan;36(1):11-20

Key Laboratory of Ministry of Health for Forensic Sciences, School of Medicine, Xi'an.

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January 2014

Th17 cell plays a role in the pathogenesis of Hashimoto's thyroiditis in patients.

Clin Immunol 2013 Dec 11;149(3):411-20. Epub 2013 Oct 11.

Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, PR China.

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http://dx.doi.org/10.1016/j.clim.2013.10.001DOI Listing
December 2013

Innate immune cell-derived microparticles facilitate hepatocarcinoma metastasis by transferring integrin α(M)β₂ to tumor cells.

J Immunol 2013 Sep 16;191(6):3453-61. Epub 2013 Aug 16.

Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, People's Republic of China.

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http://dx.doi.org/10.4049/jimmunol.1300171DOI Listing
September 2013

[Effectiveness of penile ventral scrotum cohesion place wedge cutting and improved Brisson technique for congenital buried penis].

Authors:
Huafeng Zhang

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2013 Sep;27(9):1102-5

Department of Pediatric Surgery, Yishui Central Hospital of Linyi, Linyi Shandong, 276400, P.R.China.

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September 2013

Delivery of chemotherapeutic drugs in tumour cell-derived microparticles.

Nat Commun 2012 ;3:1282

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

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http://dx.doi.org/10.1038/ncomms2282DOI Listing
June 2013

Spontaneous miscarriages are explained by the stress/glucocorticoid/lipoxin A4 axis.

J Immunol 2013 Jun 15;190(12):6051-8. Epub 2013 May 15.

Department of Gynecology and Obstetrics, First Affiliated Hospital, Wenzhou Medical College, Wenzhou 325003, People's Republic of China.

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http://dx.doi.org/10.4049/jimmunol.1202807DOI Listing
June 2013

Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis.

J Clin Invest 2013 Jan 17;123(1):189-205. Epub 2012 Dec 17.

Vascular Program, Johns Hopkins Institute for Cell Engineering, 733 North Broadway, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1172/JCI64993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533298PMC
January 2013

Microparticles released by Listeria monocytogenes-infected macrophages are required for dendritic cell-elicited protective immunity.

Cell Mol Immunol 2012 Nov 8;9(6):489-96. Epub 2012 Oct 8.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1038/cmi.2012.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002214PMC
November 2012

Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells.

Proc Natl Acad Sci U S A 2012 Oct 10;109(40):E2707-16. Epub 2012 Sep 10.

Vascular Program, Institute for Cell Engineering, McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1214019109
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http://dx.doi.org/10.1073/pnas.1214019109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479586PMC
October 2012

MicroRNAs and the Warburg Effect: new players in an old arena.

Curr Gene Ther 2012 Aug;12(4):285-91

School of Life Science, University of Science and Technology of China, Hefei, China.

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August 2012

TLR4 signaling induces the release of microparticles by tumor cells that regulate inflammatory cytokine IL-6 of macrophages via microRNA let-7b.

Oncoimmunology 2012 Aug;1(5):687-693

Department of Biochemistry and Molecular Biology; Tongji Medical College; Huazhong University of Science and Technology; Wuhan, China ; Department of Breast and Thyroid Surgery; Union Hospital; Tongji Medical College; Huazhong University of Science and Technology; Wuhan, China.

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http://dx.doi.org/10.4161/onci.19854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429572PMC
August 2012

Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.

J Mol Med (Berl) 2012 Jul 10;90(7):803-15. Epub 2012 Jan 10.

Vascular Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1007/s00109-011-0855-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437551PMC
July 2012

Soft fibrin gels promote selection and growth of tumorigenic cells.

Nat Mater 2012 Jul 1;11(8):734-41. Epub 2012 Jul 1.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.

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http://dx.doi.org/10.1038/nmat3361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405191PMC
July 2012

Epidemiological characteristics of adult SCIWORA in Tianjin, China: a preliminary study.

Eur Spine J 2012 Jan 27;21(1):165-71. Epub 2011 Oct 27.

Department of Orthopaedic Surgery, General Hospital of Tianjin Medical University, 154 Anshan Avenue, Tianjin, 300052, China. [corrected]

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http://dx.doi.org/10.1007/s00586-011-2041-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252444PMC
January 2012

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.

Proc Natl Acad Sci U S A 2011 Sep 12;108(39):16369-74. Epub 2011 Sep 12.

Institute for Cell Engineering, McKusick-Nathans Institute of Genetic Medicine, and Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1113483108
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http://dx.doi.org/10.1073/pnas.1113483108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182724PMC
September 2011

Microparticles mediate enzyme transfer from platelets to mast cells: a new pathway for lipoxin A4 biosynthesis.

Biochem Biophys Res Commun 2010 Sep 27;400(3):432-6. Epub 2010 Aug 27.

Department of Pathophysiology, Tonji Medical College, Huazhong University of Science & Technology, Wuhan 430030, PR China.

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http://dx.doi.org/10.1016/j.bbrc.2010.08.095DOI Listing
September 2010

Digoxin inhibits retinal ischemia-induced HIF-1alpha expression and ocular neovascularization.

FASEB J 2010 Jun 11;24(6):1759-67. Epub 2010 Jan 11.

Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://www.fasebj.org/doi/10.1096/fj.09-145664
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874483PMC
June 2010

N4BP1 is a newly identified nucleolar protein that undergoes SUMO-regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodies.

J Cell Sci 2010 Apr 16;123(Pt 8):1227-34. Epub 2010 Mar 16.

Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute, NCI-Frederick, Frederick, MD 21702, USA.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.060160
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http://dx.doi.org/10.1242/jcs.060160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848111PMC
April 2010

Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization.

Proc Natl Acad Sci U S A 2009 Oct 1;106(42):17910-5. Epub 2009 Oct 1.

Vascular Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0909353106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764905PMC
October 2009

Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth.

Proc Natl Acad Sci U S A 2008 Dec 19;105(50):19579-86. Epub 2008 Nov 19.

Vascular Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0809763105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604945PMC
December 2008

The expanding universe of hypoxia.

J Mol Med (Berl) 2008 Jul 13;86(7):739-46. Epub 2008 Jun 13.

Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1007/s00109-008-0364-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720566PMC
July 2008