Huafang Lai

Huafang Lai

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Huafang Lai

Huafang Lai

Publications by authors named "Huafang Lai"

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Role of contacts in long-range protein conductance.

Proc Natl Acad Sci U S A 2019 03 7;116(13):5886-5891. Epub 2019 Mar 7.

Biodesign Institute, Arizona State University, Tempe, AZ 85287;

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http://dx.doi.org/10.1073/pnas.1819674116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442609PMC
March 2019

A plant-produced vaccine protects mice against lethal West Nile virus infection without enhancing Zika or dengue virus infectivity.

Vaccine 2018 03 26;36(14):1846-1852. Epub 2018 Feb 26.

The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2018.02.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851867PMC
March 2018

Plant-produced Zika virus envelope protein elicits neutralizing immune responses that correlate with protective immunity against Zika virus in mice.

Plant Biotechnol J 2018 02 23;16(2):572-580. Epub 2017 Aug 23.

The Biodesign Institute, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1111/pbi.12796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768464PMC
February 2018

Development of Antibody Therapeutics against Flaviviruses.

Int J Mol Sci 2017 Dec 25;19(1). Epub 2017 Dec 25.

The Biodesign Institute, School of Life Sciences, Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.3390/ijms19010054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796004PMC
December 2017

Virus-like particles that display Zika virus envelope protein domain III induce potent neutralizing immune responses in mice.

Sci Rep 2017 08 9;7(1):7679. Epub 2017 Aug 9.

The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.

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http://dx.doi.org/10.1038/s41598-017-08247-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550446PMC
August 2017

Immunization of Zika virus envelope protein domain III induces specific and neutralizing immune responses against Zika virus.

Vaccine 2017 07 29;35(33):4287-4294. Epub 2017 Jun 29.

The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA; School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.04.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546088PMC
July 2017

Plant-produced anti-dengue virus monoclonal antibodies exhibit reduced antibody-dependent enhancement of infection activity.

J Gen Virol 2016 Dec 20;97(12):3280-3290. Epub 2016 Oct 20.

The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1099/jgv.0.000635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756494PMC
December 2016

Transient Protein Expression by Agroinfiltration in Lettuce.

Methods Mol Biol 2016 ;1385:55-67

The Biodesign Institute, Arizona State University, Tempe, AZ, 85225, USA.

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http://dx.doi.org/10.1007/978-1-4939-3289-4_4DOI Listing
October 2016

Corrigendum to "Purification of monoclonal antibody against Ebola GP1 protein expressed in Nicotiana benthamiana" [J. Chromatogr. A 1389 (2015) 128-132].

J Chromatogr A 2016 May 27;1448:127. Epub 2016 Apr 27.

Department of Biological Systems Engineering, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2016.04.050DOI Listing
May 2016

Gene delivery into plant cells for recombinant protein production.

Biomed Res Int 2015 17;2015:932161. Epub 2015 May 17.

Center for Infectious Disease and Vaccinology, The Biodesign Institute, Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1155/2015/932161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449920PMC
March 2016

Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile virus.

PLoS One 2014 27;9(3):e93541. Epub 2014 Mar 27.

The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America; College of Technology and Innovation, Arizona State University, Mesa, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093541PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968140PMC
May 2015

Purification of monoclonal antibody against Ebola GP1 protein expressed in Nicotiana benthamiana.

J Chromatogr A 2015 Apr 11;1389:128-32. Epub 2015 Feb 11.

Department of Biological Systems Engineering, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2015.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843992PMC
April 2015

A plant-produced antigen elicits potent immune responses against West Nile virus in mice.

Biomed Res Int 2014 3;2014:952865. Epub 2014 Apr 3.

The Biodesign Institute, Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287, USA ; School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1155/2014/952865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996298PMC
January 2015

Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins.

J Vis Exp 2013 Jul 23(77). Epub 2013 Jul 23.

The College of Technology and Innovation, Center for Infectious Disease and Vaccinology, The Biodesign Institute, Arizona State University, Arizona, USA.

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http://dx.doi.org/10.3791/50521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846102PMC
July 2013

Plant-derived virus-like particles as vaccines.

Hum Vaccin Immunother 2013 Jan 20;9(1):26-49. Epub 2012 Sep 20.

Center for Infectious Diseases and Vaccinology, Biodesign Institute at Arizona State University, Tempe, AZ USA.

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http://dx.doi.org/10.4161/hv.22218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667944PMC
January 2013

A novel system for rapid and cost-effective production of detection and diagnostic reagents of West Nile virus in plants.

J Biomed Biotechnol 2012 4;2012:106783. Epub 2011 Dec 4.

The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1155/2012/106783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236498PMC
May 2012

Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations.

Plant Cell Rep 2012 Mar 2;31(3):573-84. Epub 2011 Dec 2.

The Center for Infectious Diseases and Vaccinology, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1007/s00299-011-1196-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278561PMC
March 2012

Robust production of virus-like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce.

Plant Biotechnol J 2012 Jan 26;10(1):95-104. Epub 2011 Aug 26.

The Biodesign Institute and College of Technology and Innovation, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1111/j.1467-7652.2011.00649.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232331PMC
January 2012

Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana.

Plant Biotechnol J 2011 Sep 1;9(7):807-16. Epub 2011 Feb 1.

Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1111/j.1467-7652.2011.00593.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022790PMC
September 2011

Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice.

Proc Natl Acad Sci U S A 2010 Feb 1;107(6):2419-24. Epub 2010 Feb 1.

The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1073/pnas.0914503107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823901PMC
February 2010

Identification of pyruvate carboxylase genes in Pseudomonas aeruginosa PAO1 and development of a P. aeruginosa-based overexpression system for alpha4- and alpha4beta4-type pyruvate carboxylases.

Appl Environ Microbiol 2006 Dec 22;72(12):7785-92. Epub 2006 Sep 22.

Virginia Bioinformatics Institute, Department of Biochemistry, Virginia Polytechnic Institute and State University, Washington Street, MC 0477, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1128/AEM.01564-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1694264PMC
December 2006