Hua-Li Qin - Boston University

Hua-Li Qin

Boston University

United States

Hua-Li Qin - Boston University

Hua-Li Qin

Introduction

Primary Affiliation: Boston University - United States

Publications

25Publications

454Reads

1640Profile Views

50PubMed Central Citations

Synthesis and mechanistic studies of curcumin analog-based oximes as potential anticancer agents.

Chem Biol Drug Des 2017 Sep 6;90(3):443-449. Epub 2017 Mar 6.

Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, China.

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http://dx.doi.org/10.1111/cbdd.12964DOI Listing
September 2017
49 Reads
3 Citations
2.485 Impact Factor

Coumarins scaffolds as COX inhibitors.

Bioorg Chem 2017 04 9;71:146-159. Epub 2017 Feb 9.

School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, China. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2017.02.001DOI Listing
April 2017
6 Reads
1 Citation
2.152 Impact Factor

Synthesis of new arylisoxazole-oxindole conjugates as potent antiproliferative agents.

Chem Biol Drug Des 2017 04 19;89(4):634-638. Epub 2016 Nov 19.

Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, China.

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http://dx.doi.org/10.1111/cbdd.12884DOI Listing
April 2017
7 Reads
1 Citation
2.485 Impact Factor

Cooperativity of axial and centre chirality in the biaryl disulfoxide/Rh(i)-catalysed asymmetric 1,4-addition of arylboronic aids to 2-cyclohexenone: a DFT study.

Org Biomol Chem 2017 Mar;15(10):2226-2233

School of Chemistry and Chemical Engineering, Hefei University of Technology, 193 Tunxi Rd, 23009 Hefei, China.

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http://dx.doi.org/10.1039/c6ob02651fDOI Listing
March 2017
11 Reads
3.562 Impact Factor

Evaluation of multifunctional synthetic tetralone derivatives for treatment of Alzheimer's disease.

Chem Biol Drug Des 2016 Dec 17;88(6):889-898. Epub 2016 Aug 17.

Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, China.

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http://dx.doi.org/10.1111/cbdd.12822DOI Listing
December 2016
15 Reads
2.485 Impact Factor

A Heck-Matsuda Process for the Synthesis of β-Arylethenesulfonyl Fluorides: Selectively Addressable Bis-electrophiles for SuFEx Click Chemistry.

Angew Chem Int Ed Engl 2016 11 10;55(45):14155-14158. Epub 2016 Oct 10.

Department of Chemistry, The Scripps Research Institute, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1002/anie.201608807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102157PMC
November 2016
37 Reads
6 Citations
11.261 Impact Factor

Drug nanocarrier, the future of atopic diseases: Advanced drug delivery systems and smart management of disease.

Colloids Surf B Biointerfaces 2016 Nov 20;147:475-491. Epub 2016 Aug 20.

Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan, 430070, PR China.

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http://dx.doi.org/10.1016/j.colsurfb.2016.08.027DOI Listing
November 2016
14 Reads
4.152 Impact Factor

Natural Proline-Rich Cyclopolypeptides from Marine Organisms: Chemistry, Synthetic Methodologies and Biological Status.

Mar Drugs 2016 Oct 26;14(11). Epub 2016 Oct 26.

Laboratory of Peptide Research and Development, School of Pharmacy, Faculty of Medical Sciences, The University of the West Indies, Saint Augustine, Trinidad and Tobago, West Indies.

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http://dx.doi.org/10.3390/md14110194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128737PMC
October 2016
11 Reads
8 Citations
2.853 Impact Factor

Palladium-catalyzed Mizoroki-Heck-type reactions of [PhSR][OTf] with alkenes at room temperature.

Chem Commun (Camb) 2016 Sep;52(80):11893-11896

School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan 430070, China.

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http://dx.doi.org/10.1039/c6cc06089gDOI Listing
September 2016
21 Reads
6.834 Impact Factor

Pd-catalyzed divergent trifluoroethylation and arylation of arylboronic acids by aryl(2,2,2-trifluoroethyl)iodonium triflates.

Org Biomol Chem 2016 Aug;14(32):7654-8

School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan, 430070, China.

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http://dx.doi.org/10.1039/c6ob01384hDOI Listing
August 2016
30 Reads
1 Citation
3.562 Impact Factor

Silver-mediated direct trifluoromethoxylation of α-diazo esters via the (-)OCF3 anion.

Chem Commun (Camb) 2016 Jun 28;52(47):7458-61. Epub 2016 Apr 28.

School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan, 40003, China.

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http://dx.doi.org/10.1039/c6cc03040hDOI Listing
June 2016
14 Reads
2 Citations
6.834 Impact Factor

Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.

Bioorg Med Chem 2016 05 8;24(10):2352-9. Epub 2016 Apr 8.

Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.04.015DOI Listing
May 2016
22 Reads
2.793 Impact Factor

Palladium-Catalyzed Arylation of Arylboronic Acids with Yagupolskii-Umemoto Reagents.

Chemistry 2016 May 23;22(19):6542-6. Epub 2016 Mar 23.

School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan, 430070, P. R. China.

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http://dx.doi.org/10.1002/chem.201600991DOI Listing
May 2016
10 Reads
5.731 Impact Factor

Synthesis of α,β-Unsaturated Carbonyl-Based Compounds, Oxime and Oxime Ether Analogs as Potential Anticancer Agents for Overcoming Cancer Multidrug Resistance by Modulation of Efflux Pumps in Tumor Cells.

J Med Chem 2016 Apr 4;59(7):3549-61. Epub 2016 Apr 4.

Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia , Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1021/acs.jmedchem.6b00276DOI Listing
April 2016
39 Reads
3 Citations
5.450 Impact Factor

A Metal-Free Diverse Synthesis of Difluoromethylthioethers and Difluorobis(arylthio)methanes from RSX (X = SR, Cl, SO2Ph) and TMSCF2H.

J Org Chem 2016 Mar 9;81(6):2506-12. Epub 2016 Mar 9.

School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology , 205 Luoshi Road, Wuhan, 430070, China.

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http://dx.doi.org/10.1021/acs.joc.6b00089DOI Listing
March 2016
7 Reads
1 Citation
4.721 Impact Factor

Transmetalation from B to Rh in the course of the catalytic asymmetric 1,4-addition reaction of phenylboronic acid to enones: a computational comparison of diphosphane and diene ligands.

Dalton Trans 2015 Feb;44(6):2737-46

School of Chemistry and Chemical Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei 230009, China.

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http://dx.doi.org/10.1039/c4dt03147dDOI Listing
February 2015
62 Reads
4.200 Impact Factor

The challenge of linear (E)-enones in the Rh-catalyzed, asymmetric 1,4-addition reaction of phenylboronic acid: a DFT computational analysis.

Chemistry 2015 Feb 29;21(7):3079-86. Epub 2014 Dec 29.

Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan, 430070 (P. R. China).

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http://dx.doi.org/10.1002/chem.201405189DOI Listing
February 2015
25 Reads
5.731 Impact Factor

TfOH-catalyzed synthesis of 3-aryl isoindolinones via a tandem reaction.

Chem Commun (Camb) 2014 Dec 5;50(99):15780-3. Epub 2014 Nov 5.

Department of Pharmaceutical Engineering, Wuhan University of Technology, Wuhan, 430070, China.

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http://dx.doi.org/10.1039/c4cc06653gDOI Listing
December 2014
10 Reads
6.834 Impact Factor

A first-principles examination of the asymmetric induction model in the binap/Rh(I)-catalysed 1,4-addition of phenylboronic acid to cyclic enones by density functional theory calculations.

Chemistry 2014 Sep 28;20(40):12982-7. Epub 2014 Aug 28.

Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Rd., Wuhan 430070 (P. R. China), Fax: (+86) 2787749379.

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http://dx.doi.org/10.1002/chem.201402451DOI Listing
September 2014
22 Reads
5.731 Impact Factor

Biological activity and molecular docking studies of curcumin-related α,β-unsaturated carbonyl-based synthetic compounds as anticancer agents and mushroom tyrosinase inhibitors.

J Agric Food Chem 2014 Jun 10;62(24):5538-47. Epub 2014 Jun 10.

Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia , Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1021/jf501145bDOI Listing
June 2014
18 Reads
6 Citations
2.912 Impact Factor

Total synthesis of the Hsp90 inhibitor geldanamycin.

Org Lett 2008 Jun 20;10(12):2477-9. Epub 2008 May 20.

Department of Chemistry and Center for Chemical Methodology and Library Development, Metcalf Center for Science and Engineering, Boston University, Boston, MA 02215, USA.

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http://dx.doi.org/10.1021/ol800749wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430885PMC
June 2008
7 Reads
13 Citations

Mild reductive opening of aryl pyranosides promoted by scandium(III) triflate.

J Am Chem Soc 2007 Jan;129(1):38-9

Department of Chemistry and Center for Chemical Methodology and Library Development, Metcalf Center for Science and Engineering, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1021/ja067234oDOI Listing
January 2007
4 Reads
3 Citations
12.113 Impact Factor

Effect of environment on extremely severe road traffic crashes: retrospective epidemic analysis during 2000-2001.

Chin J Traumatol 2004 Dec;7(6):323-9

Institute for Traffic Medicine, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, China.

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December 2004
6 Reads
1 Citation

[Expressional change of nitric oxide synthases in dorsal root ganglia of cats after selective dorsal rhizotomy].

Sichuan Da Xue Xue Bao Yi Xue Ban 2004 Jan;35(1):29-31

Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Foresic Medicine, Sichuan University, Chengdu 610041, China.

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January 2004
5 Reads
1 Citation

Regioselective synthesis of 1,2,3-triazole derivatives via 1,3-dipolar cycloaddition reactions in water.

Chem Commun (Camb) 2003 Oct(19):2450-1

Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, PR China.

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October 2003
2 Reads
6.834 Impact Factor