Hua Ling

Hua Ling

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Hua Ling

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Alkaloids of dendrobium nobile lindl. Altered hepatic lipid homeostasis via regulation of bile acids.

J Ethnopharmacol 2019 Sep 24;241:111976. Epub 2019 May 24.

Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi City, Guizhou, 563009, China. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2019.111976DOI Listing
September 2019

A novel synchronization approach using synthetic magnetic .

Synth Syst Biotechnol 2019 Sep 15;4(3):130-131. Epub 2019 Jun 15.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore.

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http://dx.doi.org/10.1016/j.synbio.2019.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582162PMC
September 2019

A rare case of purpuric rash caused by Saprochaete clavata in a pediatric patient with acute leukemia.

Pediatr Dermatol 2019 Aug 18. Epub 2019 Aug 18.

Dermatology Service, KK Women's and Children's Hospital, Singapore City, Singapore.

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http://dx.doi.org/10.1111/pde.13963DOI Listing
August 2019

Engineering Yarrowia lipolytica towards food waste bioremediation: Production of fatty acid ethyl esters from vegetable cooking oil.

J Biosci Bioeng 2019 Jul 15. Epub 2019 Jul 15.

NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), Centre for Life Sciences, National University of Singapore, 28 Medical Drive, 117456, Singapore; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, 117596, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jbiosc.2019.06.009DOI Listing
July 2019

The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopenia.

Am J Hematol 2019 Jul 26. Epub 2019 Jul 26.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/ajh.25592DOI Listing
July 2019

Synthetic Biology Toolkits for Metabolic Engineering of Cyanobacteria.

Biotechnol J 2019 Jun 17;14(6):e1800496. Epub 2019 May 17.

Department of Biochemistry Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, Singapore, 117597, Singapore.

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http://dx.doi.org/10.1002/biot.201800496DOI Listing
June 2019

Meta-Omics- and Metabolic Modeling-Assisted Deciphering of Human Microbiota Metabolism.

Biotechnol J 2019 May 30:e1800445. Epub 2019 May 30.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, Singapore, 117597, Singapore.

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http://dx.doi.org/10.1002/biot.201800445DOI Listing
May 2019

Influenza A(H7N9) virus emerged and resulted in human infections in Chongqing, southwestern China since 2017.

Int J Infect Dis 2019 Apr 21;81:244-250. Epub 2019 Feb 21.

Department of Epidemiology, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing 400038, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2019.02.011DOI Listing
April 2019

The effect of parity on longitudinal maternal hemodynamics.

Am J Obstet Gynecol 2019 Apr 2. Epub 2019 Apr 2.

Fetal Medicine Research Institute, London UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2019.03.027DOI Listing
April 2019

Synthetic genetic circuits for programmable biological functionalities.

Biotechnol Adv 2019 Apr 30:107393. Epub 2019 Apr 30.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, Singapore 117597, Singapore; NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), National University of Singapore, 28 Medical Drive, Singapore 117456, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.biotechadv.2019.04.015DOI Listing
April 2019

Discovery of common and rare genetic risk variants for colorectal cancer.

Authors:
Jeroen R Huyghe Stephanie A Bien Tabitha A Harrison Hyun Min Kang Sai Chen Stephanie L Schmit David V Conti Conghui Qu Jihyoun Jeon Christopher K Edlund Peyton Greenside Michael Wainberg Fredrick R Schumacher Joshua D Smith David M Levine Sarah C Nelson Nasa A Sinnott-Armstrong Demetrius Albanes M Henar Alonso Kristin Anderson Coral Arnau-Collell Volker Arndt Christina Bamia Barbara L Banbury John A Baron Sonja I Berndt Stéphane Bézieau D Timothy Bishop Juergen Boehm Heiner Boeing Hermann Brenner Stefanie Brezina Stephan Buch Daniel D Buchanan Andrea Burnett-Hartman Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Sergi Castellví-Bel Andrew T Chan Jenny Chang-Claude Stephen J Chanock Maria-Dolores Chirlaque Sang Hee Cho Charles M Connolly Amanda J Cross Katarina Cuk Keith R Curtis Albert de la Chapelle Kimberly F Doheny David Duggan Douglas F Easton Sjoerd G Elias Faye Elliott Dallas R English Edith J M Feskens Jane C Figueiredo Rocky Fischer Liesel M FitzGerald David Forman Manish Gala Steven Gallinger W James Gauderman Graham G Giles Elizabeth Gillanders Jian Gong Phyllis J Goodman William M Grady John S Grove Andrea Gsur Marc J Gunter Robert W Haile Jochen Hampe Heather Hampel Sophia Harlid Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Wan-Ling Hsu Wen-Yi Huang Thomas J Hudson David J Hunter Gemma Ibañez-Sanz Gregory E Idos Roxann Ingersoll Rebecca D Jackson Eric J Jacobs Mark A Jenkins Amit D Joshi Corinne E Joshu Temitope O Keku Timothy J Key Hyeong Rok Kim Emiko Kobayashi Laurence N Kolonel Charles Kooperberg Tilman Kühn Sébastien Küry Sun-Seog Kweon Susanna C Larsson Cecelia A Laurie Loic Le Marchand Suzanne M Leal Soo Chin Lee Flavio Lejbkowicz Mathieu Lemire Christopher I Li Li Li Wolfgang Lieb Yi Lin Annika Lindblom Noralane M Lindor Hua Ling Tin L Louie Satu Männistö Sanford D Markowitz Vicente Martín Giovanna Masala Caroline E McNeil Marilena Melas Roger L Milne Lorena Moreno Neil Murphy Robin Myte Alessio Naccarati Polly A Newcomb Kenneth Offit Shuji Ogino N Charlotte Onland-Moret Barbara Pardini Patrick S Parfrey Rachel Pearlman Vittorio Perduca Paul D P Pharoah Mila Pinchev Elizabeth A Platz Ross L Prentice Elizabeth Pugh Leon Raskin Gad Rennert Hedy S Rennert Elio Riboli Miguel Rodríguez-Barranco Jane Romm Lori C Sakoda Clemens Schafmayer Robert E Schoen Daniela Seminara Mitul Shah Tameka Shelford Min-Ho Shin Katerina Shulman Sabina Sieri Martha L Slattery Melissa C Southey Zsofia K Stadler Christa Stegmaier Yu-Ru Su Catherine M Tangen Stephen N Thibodeau Duncan C Thomas Sushma S Thomas Amanda E Toland Antonia Trichopoulou Cornelia M Ulrich David J Van Den Berg Franzel J B van Duijnhoven Bethany Van Guelpen Henk van Kranen Joseph Vijai Kala Visvanathan Pavel Vodicka Ludmila Vodickova Veronika Vymetalkova Korbinian Weigl Stephanie J Weinstein Emily White Aung Ko Win C Roland Wolf Alicja Wolk Michael O Woods Anna H Wu Syed H Zaidi Brent W Zanke Qing Zhang Wei Zheng Peter C Scacheri John D Potter Michael C Bassik Anshul Kundaje Graham Casey Victor Moreno Goncalo R Abecasis Deborah A Nickerson Stephen B Gruber Li Hsu Ulrike Peters

Nat Genet 2019 01 3;51(1):76-87. Epub 2018 Dec 3.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41588-018-0286-6
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http://dx.doi.org/10.1038/s41588-018-0286-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437PMC
January 2019

Outbreak of Acute Gastroenteritis Caused by Norovirus Genogroup II Attributed to Contaminated Cold Dishes on a Cruise Ship in Chongqing, China, 2017.

Int J Environ Res Public Health 2018 12 11;15(12). Epub 2018 Dec 11.

Chongqing Municipal Center for Disease Control and Prevention, Chongqing, No. 8, Changjiang 2nd Road, Yuzhong District, Chongqing 400042, China.

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http://dx.doi.org/10.3390/ijerph15122823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314004PMC
December 2018

WITHDRAWN: CRISPR/Cas9 mediated HPV and PD1 inhibition produces a synergistic anti-tumor effect on cervical cancer.

Arch Biochem Biophys 2018 Oct 11. Epub 2018 Oct 11.

Center for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China; Key Laboratory for Tumor Precision Medicine of Shaanxi Province, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.1016/j.abb.2018.10.004DOI Listing
October 2018

Targeted Approaches for In Situ Gut Microbiome Manipulation.

Genes (Basel) 2018 Jul 12;9(7). Epub 2018 Jul 12.

Department of Biochemistry, Yong Loo Lin School of Medicine, 8 Medical Drive, Singapore 117596, Singapore.

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http://dx.doi.org/10.3390/genes9070351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071227PMC
July 2018

Gypenosides Altered Hepatic Bile Acids Homeostasis in Mice Treated with High Fat Diet.

Evid Based Complement Alternat Med 2018 12;2018:8098059. Epub 2018 Jul 12.

Key Lab of the Basic Pharmacology of the Ministry of Education, Zunyi Medical University, 6 West Xue-Fu Road, Zunyi City, Guizhou 563009, China.

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http://dx.doi.org/10.1155/2018/8098059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076974PMC
July 2018

Epidemiological Characteristics and Spatial-Temporal Distribution of Hand, Foot, and Mouth Disease in Chongqing, China, 2009-2016.

Int J Environ Res Public Health 2018 02 5;15(2). Epub 2018 Feb 5.

Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, No. 27, Nanwei Road, Xicheng District, Beijing 100050, China.

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http://dx.doi.org/10.3390/ijerph15020270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858339PMC
February 2018

Rewriting the Metabolic Blueprint: Advances in Pathway Diversification in Microorganisms.

Front Microbiol 2018 12;9:155. Epub 2018 Feb 12.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.3389/fmicb.2018.00155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816047PMC
February 2018

Ca2+/Mg2+ homeostasis‑related TRPM7 channel mediates chondrocyte hypertrophy via regulation of the PI3K‑Akt signaling pathway.

Mol Med Rep 2017 Oct 21;16(4):5699-5705. Epub 2017 Aug 21.

Department of Orthopedics and Trauma, Xi'an Honghui Hospital, Affiliated to School of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, P.R. China.

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http://dx.doi.org/10.3892/mmr.2017.7300DOI Listing
October 2017

Ethnicity of Patients With Germline -Activating Variants and Primary Hyperparathyroidism.

J Endocr Soc 2017 May 23;1(5):488-499. Epub 2017 Mar 23.

The National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1210/js.2017-00043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686704PMC
May 2017

Microbiome engineering: Current applications and its future.

Biotechnol J 2017 Mar 30;12(3). Epub 2017 Jan 30.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1002/biot.201600099DOI Listing
March 2017

Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer.

Oncotarget 2017 Feb;8(6):9634-9646

Center for Translational Medicine, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, P.R. China.

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http://dx.doi.org/10.18632/oncotarget.14176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354759PMC
February 2017

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.

Authors:
Christopher I Amos Joe Dennis Zhaoming Wang Jinyoung Byun Fredrick R Schumacher Simon A Gayther Graham Casey David J Hunter Thomas A Sellers Stephen B Gruber Alison M Dunning Kyriaki Michailidou Laura Fachal Kimberly Doheny Amanda B Spurdle Yafang Li Xiangjun Xiao Jane Romm Elizabeth Pugh Gerhard A Coetzee Dennis J Hazelett Stig E Bojesen Charlisse Caga-Anan Christopher A Haiman Ahsan Kamal Craig Luccarini Daniel Tessier Daniel Vincent François Bacot David J Van Den Berg Stefanie Nelson Stephen Demetriades David E Goldgar Fergus J Couch Judith L Forman Graham G Giles David V Conti Heike Bickeböller Angela Risch Melanie Waldenberger Irene Brüske-Hohlfeld Belynda D Hicks Hua Ling Lesley McGuffog Andrew Lee Karoline Kuchenbaecker Penny Soucy Judith Manz Julie M Cunningham Katja Butterbach Zsofia Kote-Jarai Peter Kraft Liesel FitzGerald Sara Lindström Marcia Adams James D McKay Catherine M Phelan Sara Benlloch Linda E Kelemen Paul Brennan Marjorie Riggan Tracy A O'Mara Hongbing Shen Yongyong Shi Deborah J Thompson Marc T Goodman Sune F Nielsen Andrew Berchuck Sylvie Laboissiere Stephanie L Schmit Tameka Shelford Christopher K Edlund Jack A Taylor John K Field Sue K Park Kenneth Offit Mads Thomassen Rita Schmutzler Laura Ottini Rayjean J Hung Jonathan Marchini Ali Amin Al Olama Ulrike Peters Rosalind A Eeles Michael F Seldin Elizabeth Gillanders Daniela Seminara Antonis C Antoniou Paul D P Pharoah Georgia Chenevix-Trench Stephen J Chanock Jacques Simard Douglas F Easton

Cancer Epidemiol Biomarkers Prev 2017 01 3;26(1):126-135. Epub 2016 Oct 3.

Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224974PMC
January 2017

Generating Exome Enriched Sequencing Libraries from Formalin-Fixed, Paraffin-Embedded Tissue DNA for Next-Generation Sequencing.

Curr Protoc Hum Genet 2017 01 11;92:18.10.1-18.10.25. Epub 2017 Jan 11.

Center for Inherited Disease Research, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1002/cphg.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228582PMC
January 2017

[Analysis of epidemiological characteristics of imported malaria cases in Chongqing Municipality in 2015].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2016 Dec;29(3):374-376

Chongqing Municipal Center for Disease Control and Prevention, Chongqing 400042, China.

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http://dx.doi.org/10.16250/j.32.1374.2016202DOI Listing
December 2016

Clinical efficacy and safety of evolocumab for low-density lipoprotein cholesterol reduction.

Vasc Health Risk Manag 2016 19;12:163-9. Epub 2016 Apr 19.

Department of Pharmacy Practice, School of Pharmacy, Hampton University, Hampton, VA, USA.

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https://pdfs.semanticscholar.org/bd00/0b44c6fc95ebdbabc248e5
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https://www.dovepress.com/clinical-efficacy-and-safety-of-ev
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http://dx.doi.org/10.2147/VHRM.S82387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844254PMC
November 2016

GCM2-Activating Mutations in Familial Isolated Hyperparathyroidism.

Am J Hum Genet 2016 Nov 13;99(5):1034-1044. Epub 2016 Oct 13.

The National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.08.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097944PMC
November 2016

Comparison of parametric and machine methods for variable selection in simulated Genetic Analysis Workshop 19 data.

BMC Proc 2016 18;10(Suppl 7):147-152. Epub 2016 Oct 18.

Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Drive, Suite 1200, Baltimore, MD 21224 USA.

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http://dx.doi.org/10.1186/s12919-016-0021-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133476PMC
October 2016

Genetic Engineering of an Unconventional Yeast for Renewable Biofuel and Biochemical Production.

J Vis Exp 2016 09 20(115). Epub 2016 Sep 20.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore; NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), Life Sciences Institute, National University of Singapore;

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http://www.jove.com/video/54371/genetic-engineering-an-uncon
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http://dx.doi.org/10.3791/54371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092062PMC
September 2016

Engineering transcription factors to improve tolerance against alkane biofuels in Saccharomyces cerevisiae.

Biotechnol Biofuels 2015 30;8:231. Epub 2015 Dec 30.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, 117597 Singapore, Singapore ; NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), Life Sciences Institute, National University of Singapore, 28 Medical Drive, 117456 Singapore, Singapore.

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http://dx.doi.org/10.1186/s13068-015-0411-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696261PMC
December 2015

Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid short- and branched-chain alkyl esters biodiesel.

Biotechnol Biofuels 2015 4;8:177. Epub 2015 Nov 4.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore, 117597 Singapore ; NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), Life Sciences Institute, National University of Singapore, 28 Medical Drive, Singapore, 117456 Singapore.

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http://dx.doi.org/10.1186/s13068-015-0361-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634726PMC
November 2015

Assessment of incidental findings in 232 whole-exome sequences from the Baylor-Hopkins Center for Mendelian Genomics.

Genet Med 2015 Oct 8;17(10):782-8. Epub 2015 Jan 8.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/gim.2014.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496331PMC
October 2015

Virological outcomes and drug resistance in Chinese patients after 12 months of 3TC-based first-line antiretroviral treatment, 2011-2012.

PLoS One 2014 7;9(2):e88305. Epub 2014 Feb 7.

State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088305PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917868PMC
May 2015

Therapeutic microbes for infectious disease.

Methods Mol Biol 2014 ;1151:117-33

School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, Singapore.

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http://dx.doi.org/10.1007/978-1-4939-0554-6_9DOI Listing
January 2015

Microbial tolerance engineering toward biochemical production: from lignocellulose to products.

Curr Opin Biotechnol 2014 Oct 17;29:99-106. Epub 2014 Apr 17.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, 117599, Singapore; Synthetic Biology Research Consortium, National University of Singapore, 28 Medical Drive, 117456, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2014.03.005DOI Listing
October 2014

Expression and biochemical characterization of recombinant human epididymis protein 4.

Protein Expr Purif 2014 Oct 13;102:52-62. Epub 2014 Aug 13.

Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.pep.2014.08.004DOI Listing
October 2014

Pfit is a structurally novel Crohn's disease-associated superantigen.

PLoS Pathog 2013 26;9(12):e1003837. Epub 2013 Dec 26.

Wadsworth Center, New York State Department of Health, Albany, New York, United States of America ; Department of Biomedical Sciences, School of Public Health, State University of New York, Albany, New York, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873459PMC
September 2014

Serum albumin changes and multivariate dynamic risk modelling in chronic heart failure.

Int J Cardiol 2014 Sep 1;176(2):437-43. Epub 2014 Aug 1.

International Centre for Circulatory Health, NHLI, Imperial College, London, UK; University College London Hospital, London, UK; The Heart Hospital, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2014.07.096DOI Listing
September 2014

In vitro and in vivo growth suppression of human papillomavirus 16-positive cervical cancer cells by CRISPR/Cas9.

Biochem Biophys Res Commun 2014 Aug 17;450(4):1422-6. Epub 2014 Jul 17.

Baoji Hospital of Traditional Chinese Medicine, No 43, BaoFu Road, Baoji City, Shanxi Province, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X140122
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http://dx.doi.org/10.1016/j.bbrc.2014.07.014DOI Listing
August 2014

Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.

Front Public Health 2014 6;2:112. Epub 2014 Aug 6.

Center for Public Health Genomics, University of Virginia , Charlottesville, VA , USA ; Department of Public Health Sciences, University of Virginia , Charlottesville, VA , USA ; Department of Biochemistry & Molecular Genetics, University of Virginia , Charlottesville, VA , USA.

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http://dx.doi.org/10.3389/fpubh.2014.00112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123605PMC
August 2014

Influence of Cofactor Regeneration Strategies on Preparative-Scale, Asymmetric Carbonyl Reductions by Engineered

Org Process Res Dev 2014 Jun 17;18(6):793-800. Epub 2014 Feb 17.

Department of Chemistry, University of Florida , 126 Sisler Hall, Gainesville, Florida 32611, United States.

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http://dx.doi.org/10.1021/op400312nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105172PMC
June 2014

Highly efficient production of peptides: N-glycosidase F for N-glycomics analysis.

Protein Expr Purif 2014 May 26;97:17-22. Epub 2014 Feb 26.

Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.pep.2014.02.004DOI Listing
May 2014

Characterization of the genomic architecture and mutational spectrum of a small cell prostate carcinoma.

Genes (Basel) 2014 May 12;5(2):366-84. Epub 2014 May 12.

Department of Pediatrics, SUNY Upstate Medical Center, Golisano Children's Hospital, Syracuse, NY 13210, USA.

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http://dx.doi.org/10.3390/genes5020366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094938PMC
May 2014

[Construction and identification of a full-length human secretory antibody library in Pichia pastoris].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2014 Jan;30(1):58-62

Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, PLA Academy of Military Medicine, Beijing 100850, China.

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January 2014

Reducing the risk of obesity: defining the role of weight loss drugs.

Pharmacotherapy 2013 Dec 26;33(12):1308-21. Epub 2013 May 26.

Creighton University Cardiac Center, Creighton University School of Medicine, Omaha, Nebraska.

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https://www.researchgate.net/profile/Hua_Ling4/publication/2
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http://dx.doi.org/10.1002/phar.1277DOI Listing
December 2013

A predicted immunity protein confers resistance to pyocin S5 in a sensitive strain of Pseudomonas aeruginosa.

Chembiochem 2013 Dec 12;14(18):2444-6. Epub 2013 Nov 12.

School of Chemical and Biomedical Engineering, Nanyang Technological University (NTU), 62 Nanyang Drive, 637459 (Singapore).

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http://dx.doi.org/10.1002/cbic.201300410DOI Listing
December 2013

Microbial engineering strategies to improve cell viability for biochemical production.

Biotechnol Adv 2013 Nov 10;31(6):903-14. Epub 2013 Feb 10.

School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore.

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http://dx.doi.org/10.1016/j.biotechadv.2013.02.001DOI Listing
November 2013

Study of drug resistance and molecular typing of 59 cholerae01 clinical isolates from 1984 to 2002 in Chongqing, China.

Int J Clin Exp Med 2013 25;6(10):930-6. Epub 2013 Oct 25.

Center for Disease Control and Prevention No.8 Changjiang 2nd Rd, Yuzhong District, 400042, Chongqing, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832330PMC
November 2013

Cyclin D1-dependent induction of luminal inflammatory breast tumors by activated notch3.

Cancer Res 2013 Oct 8;73(19):5963-73. Epub 2013 Aug 8.

Authors' Affiliations: Laboratory of Molecular Biology, Clinical Research Institute of Montreal; Department of Microbiology and Immunology Université de Montréal; and Division of Experimental Medicine, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0409DOI Listing
October 2013

Imputation-based genomic coverage assessments of current human genotyping arrays.

G3 (Bethesda) 2013 Oct 3;3(10):1795-807. Epub 2013 Oct 3.

Department of Biostatistics, University of Washington, Seattle, Washington, 98195.

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http://dx.doi.org/10.1534/g3.113.007161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789804PMC
October 2013

Transcriptome response to alkane biofuels in Saccharomyces cerevisiae: identification of efflux pumps involved in alkane tolerance.

Biotechnol Biofuels 2013 Jul 5;6(1):95. Epub 2013 Jul 5.

School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Nanyang 637459, Singapore.

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http://dx.doi.org/10.1186/1754-6834-6-95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717029PMC
July 2013

Ablative hypofractionated radiotherapy normalizes tumor vasculature in lewis lung carcinoma mice model.

Radiat Res 2013 Apr 12;179(4):458-64. Epub 2013 Mar 12.

Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1667/RR3116.1DOI Listing
April 2013

Th17-relevant cytokines vary with sera of different ANA staining patterns.

Int Immunopharmacol 2013 Apr 16;15(4):679-84. Epub 2013 Mar 16.

Department of Laboratory Medicine, Gongli Hospital, Second Military Medicine University, Pudong New Area, Shanghai, 200135, China.

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http://dx.doi.org/10.1016/j.intimp.2013.03.001DOI Listing
April 2013

A Review of Currently Available Fenofibrate and Fenofibric Acid Formulations.

Cardiol Res 2013 Apr 9;4(2):47-55. Epub 2013 May 9.

School of Pharmacy and Health Professions, Cardiac Center of Creighton University, Omaha, NE, USA.

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http://dx.doi.org/10.4021/cr270wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358213PMC
April 2013

Genomic analysis of a newly isolated of Japanese encephalitis virus strain, CQ11-66, from a pediatric patient in China.

Virol J 2013 Apr 1;10:101. Epub 2013 Apr 1.

Department of Infectious diseases and Gastroenterology, Children's Hospital of Chongqing Medical University, No. 136 Zhongshan Er Road, Yuzhong District, Chongqing 400014, PR China.

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http://dx.doi.org/10.1186/1743-422X-10-101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637482PMC
April 2013

Systems-level characterization and engineering of oxidative stress tolerance in Escherichia coli under anaerobic conditions.

Mol Biosyst 2013 Feb 7;9(2):285-95. Epub 2012 Dec 7.

Division of Chemical and Biomolecular Engineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore.

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http://dx.doi.org/10.1039/c2mb25259gDOI Listing
February 2013

Transporter engineering for improved tolerance against alkane biofuels in Saccharomyces cerevisiae.

Biotechnol Biofuels 2013 Feb 13;6(1):21. Epub 2013 Feb 13.

Division of Chemical and Biomolecular Engineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Nanyang 637459, Singapore.

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http://dx.doi.org/10.1186/1754-6834-6-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598725PMC
February 2013

Short communication: emerging transmitted HIV type 1 drug resistance mutations among patients prior to start of first-line antiretroviral therapy in middle and low prevalence sites in China.

AIDS Res Hum Retroviruses 2012 Dec 27;28(12):1637-9. Epub 2012 Aug 27.

State Key Laboratory for Infectious Disease Prevention and Control, and National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

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http://dx.doi.org/10.1089/aid.2012.0164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505058PMC
December 2012

A novel meso-Diaminopimelate dehydrogenase from Symbiobacterium thermophilum: overexpression, characterization, and potential for D-amino acid synthesis.

Appl Environ Microbiol 2012 Dec 28;78(24):8595-600. Epub 2012 Sep 28.

National Engineering Laboratory for Industrial Enzymes, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.

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http://aem.asm.org/lookup/doi/10.1128/AEM.02234-12
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http://dx.doi.org/10.1128/AEM.02234-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502910PMC
December 2012

Novel strategies for managing dyslipidemia: treatment beyond statins.

Postgrad Med 2012 Nov;124(6):43-54

The Cardiac Center of Creighton University, Omaha, NE 68131, USA.

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http://dx.doi.org/10.3810/pgm.2012.11.2612DOI Listing
November 2012

Prevalence and trend of HIV infection among voluntary blood donors in China since implementation of the Blood Donation Law: a systematic review and meta-analysis.

Trop Med Int Health 2012 Aug 12;17(8):978-88. Epub 2012 Jun 12.

Department of Social and Behavioral Health, School of Rural Public Health, Texas A&M Health Science Center, College Station, TX 77843, USA.

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http://dx.doi.org/10.1111/j.1365-3156.2012.03019.xDOI Listing
August 2012

Aliskiren in Patients Failing to Achieve Blood Pressure Targets With Angiotensin Converting Enzyme Inhibitors or Angiotensin Receptor Blockers.

Cardiol Res 2012 Aug 20;3(4):147-153. Epub 2012 Jul 20.

Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, NE, USA.

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http://dx.doi.org/10.4021/cr201wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358205PMC
August 2012

Detectable clonal mosaicism from birth to old age and its relationship to cancer.

Nat Genet 2012 May 6;44(6):642-50. Epub 2012 May 6.

Department of Biostatistics, University of Washington, Seattle, Washington, USA.

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http://www.nature.com/articles/ng.2271
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http://dx.doi.org/10.1038/ng.2271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366033PMC
May 2012

Accelerating haplotype-based genome-wide association study using perfect phylogeny and phase-known reference data.

PLoS One 2011 15;6(7):e22097. Epub 2011 Jul 15.

Department of Computational Genomics, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022097PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137625PMC
November 2011

[An outbreak of human orf disease caused by introduced black goats].

Zhonghua Liu Xing Bing Xue Za Zhi 2011 Sep;32(9):905-7

Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China.

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September 2011

Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen.

Mol Syst Biol 2011 Aug 16;7:521. Epub 2011 Aug 16.

School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore.

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http://dx.doi.org/10.1038/msb.2011.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202794PMC
August 2011

Vaccinia-related kinase 1 is required for the maintenance of undifferentiated spermatogonia in mouse male germ cells.

PLoS One 2010 Dec 13;5(12):e15254. Epub 2010 Dec 13.

Division of Molecular and Life Science, Department of Life Science, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001494PMC
December 2010

Highly enantioselective mutant carbonyl reductases created via structure-based site-saturation mutagenesis.

J Org Chem 2010 Nov 22;75(22):7559-64. Epub 2010 Oct 22.

State Engineering Laboratory for Industrial Enzymes, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.

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http://pubs.acs.org/doi/abs/10.1021/jo101541n
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November 2010

The absence of the luxS gene increases swimming motility and flagella synthesis in Escherichia coli K12.

Biochem Biophys Res Commun 2010 Oct 25;401(4):521-6. Epub 2010 Sep 25.

School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637459, Singapore.

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http://dx.doi.org/10.1016/j.bbrc.2010.09.080DOI Listing
October 2010

Hepatitis B virus-induced liver fibrosis and cirrhosis: the value of liver and spleen volumetry with multi-detector spiral computed tomography.

J Dig Dis 2010 Aug;11(4):215-23

Department of Radiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1111/j.1751-2980.2010.00441.xDOI Listing
August 2010

Flavivirus RNA cap methyltransferase: structure, function, and inhibition.

Front Biol (Beijing) 2010 Aug;5(4):286-303

Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA.

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http://dx.doi.org/10.1007/s11515-010-0660-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172701PMC
August 2010

Novel short antibacterial and antifungal peptides with low cytotoxicity: Efficacy and action mechanisms.

Biochem Biophys Res Commun 2010 Jul 11;398(3):594-600. Epub 2010 Jul 11.

School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, 637459 Singapore, Singapore.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1001288
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http://dx.doi.org/10.1016/j.bbrc.2010.06.131DOI Listing
July 2010