Howard Y Chang

Howard Y Chang

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Howard Y Chang

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Chromatin accessibility dynamics in a model of human forebrain development.

Science 2020 Jan;367(6476)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1126/science.aay1645DOI Listing
January 2020

Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia.

Nat Biotechnol 2019 12 2;37(12):1458-1465. Epub 2019 Dec 2.

Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41587-019-0332-7DOI Listing
December 2019

Tracking the immune response with single-cell genomics.

Vaccine 2019 Dec 16. Epub 2019 Dec 16.

Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2019.11.035DOI Listing
December 2019

PIRCh-seq: functional classification of non-coding RNAs associated with distinct histone modifications.

Genome Biol 2019 12 20;20(1):292. Epub 2019 Dec 20.

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, CCSR 2155c, 269 Campus Drive, Stanford, CA, 94305-5168, USA.

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http://dx.doi.org/10.1186/s13059-019-1880-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924075PMC
December 2019

The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation.

EMBO Rep 2019 10 27;20(10):e48019. Epub 2019 Aug 27.

Mammalian Developmental Epigenetics Group, Institut Curie, CNRS UMR3215, INSERM U934, PSL University, Paris, France.

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http://dx.doi.org/10.15252/embr.201948019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776897PMC
October 2019

N6-Methyladenosine Modification Controls Circular RNA Immunity.

Mol Cell 2019 Oct 29;76(1):96-109.e9. Epub 2019 Aug 29.

Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778039PMC
October 2019

Atlas of Subcellular RNA Localization Revealed by APEX-Seq.

Cell 2019 Jul 20;178(2):473-490.e26. Epub 2019 Jun 20.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Chemistry, Stanford University, Stanford, CA 94305, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786773PMC
July 2019

ChIRP-MS: RNA-Directed Proteomic Discovery.

Methods Mol Biol 2018 ;1861:37-45

Stanford University School of Medicine, Stanford, CA, USA.

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http://link.springer.com/10.1007/978-1-4939-8766-5_3
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http://dx.doi.org/10.1007/978-1-4939-8766-5_3DOI Listing
June 2019

RNA structure maps across mammalian cellular compartments.

Nat Struct Mol Biol 2019 04 18;26(4):322-330. Epub 2019 Mar 18.

MOE Key Laboratory of Bioinformatics, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

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http://www.nature.com/articles/s41594-019-0200-7
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http://dx.doi.org/10.1038/s41594-019-0200-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640855PMC
April 2019

Enhancer Connectome Nominates Target Genes of Inherited Risk Variants from Inflammatory Skin Disorders.

J Invest Dermatol 2019 Mar 10;139(3):605-614. Epub 2018 Oct 10.

Department of Dermatology, Stanford University School of Medicine, Redwood City, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.09.011DOI Listing
March 2019

TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.

Cell Stem Cell 2019 02 24;24(2):271-284.e8. Epub 2019 Jan 24.

Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, USA; Center for Definitive and Curative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909183060
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http://dx.doi.org/10.1016/j.stem.2018.12.012DOI Listing
February 2019

A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.

Immunity 2019 02 29;50(2):362-377.e6. Epub 2019 Jan 29.

Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Sean N. Parker Autoimmune Research Laboratory, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183056
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http://dx.doi.org/10.1016/j.immuni.2018.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476426PMC
February 2019

Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks.

Cell 2019 01 20;176(1-2):361-376.e17. Epub 2018 Dec 20.

Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA 94304, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329648PMC
January 2019

The RNA Base-Pairing Problem and Base-Pairing Solutions.

Cold Spring Harb Perspect Biol 2018 12 3;10(12). Epub 2018 Dec 3.

Center for Personal Dynamic Regulomes, Stanford University, Stanford, California 94305.

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http://dx.doi.org/10.1101/cshperspect.a034926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280703PMC
December 2018

A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas.

Cell Syst 2018 09 22;7(3):310-322.e4. Epub 2018 Aug 22.

Department of Developmental Biology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA; Department of Medicine, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA; Stanford Diabetes Research Center, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2018.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347013PMC
September 2018

Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations.

Proc Natl Acad Sci U S A 2018 07 9;115(30):7723-7728. Epub 2018 Jul 9.

Department of Statistics, Stanford University, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1805681115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065048PMC
July 2018

An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1.

Cell 2018 06 24;174(1):218-230.e13. Epub 2018 May 24.

Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.04.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063371PMC
June 2018

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation.

Cell 2018 05 26;173(6):1535-1548.e16. Epub 2018 Apr 26.

Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Applied Physics, Stanford University, Stanford, CA 94025, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989727PMC
May 2018

Epigenomics: Technologies and Applications.

Circ Res 2018 04;122(9):1191-1199

From the Program in Epithelial Biology (K.C.W., H.Y.C.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.310998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929475PMC
April 2018

ATAC Primer Tool for targeted analysis of accessible chromatin.

Nat Methods 2018 04;15(5):304-305

Center for Personal Dynamic Regulomes, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/nmeth.4663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942889PMC
April 2018

mA mRNA methylation sustains Treg suppressive functions.

Cell Res 2018 Feb 5;28(2):253-256. Epub 2018 Jan 5.

Shanghai Institute of Immunology, Department of Microbiology and Immunology, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China.

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http://www.nature.com/doifinder/10.1038/cr.2018.7
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http://dx.doi.org/10.1038/cr.2018.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799823PMC
February 2018

Rapid chromatin repression by Aire provides precise control of immune tolerance.

Nat Immunol 2018 02 15;19(2):162-172. Epub 2018 Jan 15.

Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41590-017-0032-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049828PMC
February 2018

Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders.

Nature 2018 02 24;554(7690):112-117. Epub 2018 Jan 24.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature25449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927778PMC
February 2018

Understanding RNA-Chromatin Interactions Using Chromatin Isolation by RNA Purification (ChIRP).

Methods Mol Biol 2016 ;1480:115-23

Center for Personal Dynamic Regulomes, Stanford University, 269 Campus Drive, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1007/978-1-4939-6380-5_10DOI Listing
January 2018

LncRNA Seduction of GOT2 Goes Viral.

Immunity 2017 12;47(6):1021-1023

Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.12.006DOI Listing
December 2017

Mechanistic insights in X-chromosome inactivation.

Philos Trans R Soc Lond B Biol Sci 2017 Nov;372(1733)

Center for Dynamic Personal Regulomes, Stanford University, Stanford, CA 94305, USA

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http://dx.doi.org/10.1098/rstb.2016.0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627158PMC
November 2017

Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia.

Front Oncol 2017 6;7:263. Epub 2017 Nov 6.

Program in Cancer Biology, Cancer Institute, Institute for Stem Cell Biology and Regenerative Medicine, Ludwig Center, Stanford University School of Medicine, Stanford, CA, United States.

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http://journal.frontiersin.org/article/10.3389/fonc.2017.002
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http://dx.doi.org/10.3389/fonc.2017.00263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681525PMC
November 2017

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.

Elife 2017 10 31;6. Epub 2017 Oct 31.

Department of Developmental Biology, Stanford University School of Medicine, Stanford, United States.

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http://dx.doi.org/10.7554/eLife.26116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703642PMC
October 2017

Two-Stage Explantation of a Magnetic Lower Esophageal Sphincter Augmentation Device Due to Esophageal Erosion.

J Laparoendosc Adv Surg Tech A 2017 Aug 10;27(8):829-833. Epub 2017 May 10.

2 Department of Surgery, Kaiser Permanente Oakland Medical Center , Oakland, California.

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http://dx.doi.org/10.1089/lap.2017.0153DOI Listing
August 2017

Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs.

Circ Res 2017 Aug 29;121(4):376-391. Epub 2017 Jun 29.

From the Department of Genetics (Q.L., C.J., K.V.B., M.P.S.), Center for Personal Dynamic Regulomes (J.X., H.Y.C.), Stanford Cardiovascular Institute (M.T.Z., J.C.W.), and Stem Cell Core Facility, Department of Genetics (X.C., G.W.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.310456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576565PMC
August 2017

Gene regulation in the immune system by long noncoding RNAs.

Nat Immunol 2017 Aug;18(9):962-972

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/ni.3771DOI Listing
August 2017

Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology.

Cold Spring Harb Perspect Med 2017 Jul 5;7(7). Epub 2017 Jul 5.

Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, California 94305.

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http://dx.doi.org/10.1101/cshperspect.a026492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495049PMC
July 2017

Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors.

Cancer Cell 2017 07 15;32(1):27-41.e4. Epub 2017 Jun 15.

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, CCSR 2155c, 269 Campus Drive, Stanford, CA 94305-5168, USA; Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559384PMC
July 2017

Sensing Self and Foreign Circular RNAs by Intron Identity.

Mol Cell 2017 Jul 15;67(2):228-238.e5. Epub 2017 Jun 15.

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610545PMC
July 2017

IL-4Rα Inhibitor for Atopic Disease.

Cell 2017 Jul;170(2):222

Stanford University School of Medicine, Stanford University, Stanford, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.06.046DOI Listing
July 2017

Generation of pure GABAergic neurons by transcription factor programming.

Nat Methods 2017 Jun 15;14(6):621-628. Epub 2017 May 15.

Institute for Stem Cell Biology and Regenerative Medicine and Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nmeth.4291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567689PMC
June 2017

The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.

Cell 2017 Jun;169(6):1051-1065.e18

Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548193PMC
June 2017

Transcription coactivator and lncRNA duet evoke Hox genes.

PLoS Genet 2017 06 29;13(6):e1006797. Epub 2017 Jun 29.

Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490938PMC
June 2017

Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.

Nat Genet 2017 Mar 23;49(3):377-386. Epub 2017 Jan 23.

Center for Personal Dynamic Regulomes, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/ng.3769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357084PMC
March 2017

Comparison of SHAPE reagents for mapping RNA structures inside living cells.

RNA 2017 02 22;23(2):169-174. Epub 2016 Nov 22.

Center for Personal Dynamic Regulomes, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1261/rna.058784.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238792PMC
February 2017

Single-cell epigenomic variability reveals functional cancer heterogeneity.

Genome Biol 2017 01 24;18(1):15. Epub 2017 Jan 24.

Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1186/s13059-016-1133-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259890PMC
January 2017

Comment on "Hotair Is Dispensable for Mouse Development".

PLoS Genet 2016 12 15;12(12):e1006406. Epub 2016 Dec 15.

Program in Epithelial Biology Stanford University School of Medicine, Stanford, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157954PMC
December 2016

An inducible long noncoding RNA amplifies DNA damage signaling.

Nat Genet 2016 11 26;48(11):1370-1376. Epub 2016 Sep 26.

Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083181PMC
http://dx.doi.org/10.1038/ng.3673DOI Listing
November 2016

HiChIP: efficient and sensitive analysis of protein-directed genome architecture.

Nat Methods 2016 Nov 19;13(11):919-922. Epub 2016 Sep 19.

Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nmeth.3999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501173PMC
November 2016

lncRNA Structure: Message to the Heart.

Mol Cell 2016 10;64(1):1-2

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.09.030DOI Listing
October 2016

Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome.

Neuron 2016 Oct 29;92(2):392-406. Epub 2016 Sep 29.

Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA; Neurosciences Program, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098476PMC
October 2016

Factors That May Promote an Effective Local Research Environment.

J Invest Dermatol 2016 08;136(8):1529-1531

Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA; Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA; Veterans Affairs Palo Alto Healthcare System, Palo Alto, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873952PMC
August 2016

CD44+ Cells in Head and Neck Squamous Cell Carcinoma Suppress T-Cell-Mediated Immunity by Selective Constitutive and Inducible Expression of PD-L1.

Clin Cancer Res 2016 07 10;22(14):3571-81. Epub 2016 Feb 10.

Division of Head and Neck Surgery, Department of Otolaryngology, Stanford Cancer Institute, Stanford, California. Program in Immunology, Stanford University School of Medicine, Stanford, California. Stanford Cancer Institute, Stanford, California. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623594PMC
July 2016

irCLIP platform for efficient characterization of protein-RNA interactions.

Nat Methods 2016 06 25;13(6):489-92. Epub 2016 Apr 25.

Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA.

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http://www.nature.com/articles/nmeth.3840
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http://dx.doi.org/10.1038/nmeth.3840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477425PMC
June 2016

A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation.

Cell 2016 Jun;165(7):1672-1685

Program in Innate Immunity, University of Massachusetts Medical School, Worcester, MA 01605, USA; Centre for Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, NTNU, 7491 Trondheim, Norway. Electronic address:

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http://www.cell.com/cell/pdf/S0092-8674(16)30722-X.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S009286741630722
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http://dx.doi.org/10.1016/j.cell.2016.05.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289747PMC
June 2016

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.

Cell Metab 2016 05 28;23(5):909-20. Epub 2016 Apr 28.

Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine (Oncology Division), Stanford University School of Medicine, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864151PMC
May 2016

Systematic Characterization of Long Noncoding RNAs Reveals the Contrasting Coordination of Cis- and Trans-Molecular Regulation in Human Fetal and Adult Hearts.

Circ Cardiovasc Genet 2016 Apr 19;9(2):110-8. Epub 2016 Feb 19.

From the Stanford Cardiovascular Institute (C.H., K.D.W., H.W., J.C., J.C.W.), Division of Cardiology, Department of Medicine (C.H., H.W., J.C., J.C.W.), Department of Pathology (K.D.W.), and Program in Epithelial Biology (K.Q., H.Y.C.), Stanford University, CA; and School of Basic Medical Science (C.H., H.H., S.X.) and International School of Software (J.F.), Wuhan University, Wuhan, China.

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http://dx.doi.org/10.1161/CIRCGENETICS.115.001264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862831PMC
April 2016

Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

Mol Cell 2016 Apr;62(1):34-46

Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836061PMC
April 2016

Long Noncoding RNAs in Cancer Pathways.

Cancer Cell 2016 Apr;29(4):452-463

Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831138PMC
April 2016

Single-cell profiling of lncRNAs in the developing human brain.

Genome Biol 2016 04 14;17:68. Epub 2016 Apr 14.

Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1186/s13059-016-0933-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831122PMC
April 2016

7SK-BAF axis controls pervasive transcription at enhancers.

Nat Struct Mol Biol 2016 Mar 15;23(3):231-8. Epub 2016 Feb 15.

Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nsmb.3176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982704PMC
March 2016

Decoding the RNA structurome.

Curr Opin Struct Biol 2016 Feb 26;36:142-8. Epub 2016 Feb 26.

Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA 94305, United States. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2016.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785074PMC
February 2016