Howard Safran

Howard Safran

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Howard Safran

Howard Safran

Publications by authors named "Howard Safran"

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: a novel gene fusion in hepatic angiosarcoma.

Oncotarget 2019 Jan 4;10(2):245-251. Epub 2019 Jan 4.

Division of Hematology-Oncology, Lifespan Cancer Institute, Warren-Alpert Medical School of Brown University, Providence, RI, USA.

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http://dx.doi.org/10.18632/oncotarget.26521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349438PMC
January 2019

Prognostic significance of IgG4+ plasma cell infiltrates following neoadjuvant chemoradiation therapy for esophageal adenocarcinoma.

Hum Pathol 2017 08 28;66:126-135. Epub 2017 Jun 28.

Department of Pathology, Rhode Island Hospital, and Alpert Medical School at Brown University, Providence, RI 02903.

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http://dx.doi.org/10.1016/j.humpath.2017.06.009DOI Listing
August 2017

Avelumab, an Anti-Programmed Death-Ligand 1 Antibody, In Patients With Refractory Metastatic Urothelial Carcinoma: Results From a Multicenter, Phase Ib Study.

J Clin Oncol 2017 Jul 4;35(19):2117-2124. Epub 2017 Apr 4.

Andrea B. Apolo and James L. Gulley, National Institutes of Health, Bethesda, MD; Jeffrey R. Infante, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Ani Balmanoukian, The Angeles Clinic & Research Institute; Alain C. Mita, Cedars Sinai Medical Center, Los Angeles; Karen Kelly, University of California-Davis, Sacramento; Marko Srdanov, Dako North America, Carpinteria, CA; Manish R. Patel, Florida Cancer Specialists & Research Institute, Sarasota, FL; Ding Wang, Henry Ford Hospital, Detroit, MI; Anthony E. Mega, The Warren Alpert Medical School at Brown University; Howard Safran, The Miriam Hospital, Providence; Howard Safran, Newport Hospital, Newport, RI; Carolyn D. Britten, Medical University of South Carolina, Charleston, SC; Alain Ravaud, CHU de Bordeaux, Bordeaux, France; Thomas E. Stinchcombe, Duke University Medical Center, Durham, NC; Arnold B. Gelb and Kevin Chin, EMD Serono, Billerica, MA; and Michael Schlichting, Merck, Darmstadt, Germany.

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http://ascopubs.org/doi/10.1200/JCO.2016.71.6795
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http://dx.doi.org/10.1200/JCO.2016.71.6795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493051PMC
July 2017

Therapeutic options for treatment of human papillomavirus-associated cancers - novel immunologic vaccines: ADXS11-001.

Gynecol Oncol Res Pract 2017 14;4:10. Epub 2017 Jul 14.

Division of Gynecologic Oncology, Arizona Oncology (US Oncology Network), University of Arizona College of Medicine, Creighton University School of Medicine at St. Joseph's Hospital, 2222 E. Highland Ave, Suite 400, Phoenix, AZ 85016 USA.

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http://dx.doi.org/10.1186/s40661-017-0047-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512733PMC
July 2017

Longitudinal DSC-MRI for Distinguishing Tumor Recurrence From Pseudoprogression in Patients With a High-grade Glioma.

Am J Clin Oncol 2017 Jun;40(3):228-234

*Department of Diagnostic Imaging Divisions of ¶Neuro-Oncology #Hematology/Oncology, Rhode Island Hospital †Warren Alpert Medical School, Brown University, Providence, RI Departments of ‡Radiological Sciences §Biomedical Physics, David Geffen School of Medicine at UCLA ∥Department of Bioengineering, Henry Samueli School of Engineering and Applied Science at UCLA, Los Angeles, CA.

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http://dx.doi.org/10.1097/COC.0000000000000156DOI Listing
June 2017

Mechanistic insights into ADXS11-001 human papillomavirus-associated cancer immunotherapy.

Gynecol Oncol Res Pract 2017 2;4. Epub 2017 Jun 2.

Brown University Oncology Research Group, Providence, RI USA.

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http://dx.doi.org/10.1186/s40661-017-0046-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455112PMC
June 2017

Stereotactic Body Radiation Therapy Boost After Concurrent Chemoradiation for Locally Advanced Non-Small Cell Lung Cancer: A Phase 1 Dose Escalation Study.

Int J Radiat Oncol Biol Phys 2016 12 31;96(5):1021-1027. Epub 2016 Aug 31.

Department of Radiation Oncology, Rhode Island Hospital, Brown University, Providence, Rhode Island; Department of Radiation Oncology, Tufts Medical Center, Tufts University, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ijrobp.2016.08.032DOI Listing
December 2016

Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target.

Clin Cancer Res 2016 08 1;22(15):3831-40. Epub 2016 Mar 1.

Oncology Division, Department of Internal Medicine, Rhode Island Hospital, and Alpert Medical School at Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-3000DOI Listing
August 2016

Optimizing initial chemotherapy for metastatic pancreatic cancer.

Future Oncol 2016 May 4;12(9):1125-33. Epub 2016 Mar 4.

The Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI 02903, USA.

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https://www.futuremedicine.com/doi/10.2217/fon-2015-0006
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http://dx.doi.org/10.2217/fon-2015-0006DOI Listing
May 2016

Mutation Profiling of Clinically Advanced Cancers Using Next-Generation Sequencing for Targeted Therapy: A Lifespan Experience.

R I Med J (2013) 2015 Oct 1;98(10):16-20. Epub 2015 Oct 1.

Director of the Brown University Oncology Group and Professor of Medicine at the Alpert Medical School of Brown University.

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October 2015

Updates in Tumor Profiling in Gastrointestinal Cancers.

R I Med J (2013) 2015 Oct 1;98(10):21-4. Epub 2015 Oct 1.

Research Director of the Comprehensive Cancer Center at Rhode Island, The Miriam and Newport hospitals and the medical director for the Brown University Oncology Group. He is a Professor of Medicine at The Warren Alpert Medical School of Brown University.

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October 2015

A Novel SDHA-deficient Renal Cell Carcinoma Revealed by Comprehensive Genomic Profiling.

Am J Surg Pathol 2015 Jun;39(6):858-63

Departments of *Pathology ‡Internal Medicine, Oncology Division, Rhode Island Hospital, and Alpert Medical School at Brown University, Providence, RI †Foundation Medicine Inc., Cambridge, MA §Department of Pathology and Laboratory Medicine, Albany Medical College, Albany, NY.

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http://dx.doi.org/10.1097/PAS.0000000000000403DOI Listing
June 2015

Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma.

Vaccine 2015 Mar 25;33(10):1256-66. Epub 2015 Jan 25.

Liver Research Center, Rhode Island Hospital and the Warren Alpert Medical School of Brown University, Providence, RI 02903, USA; Department of Medicine, Rhode Island Hospital and the Warren Alpert Medical School of Brown University, Providence, RI 02903, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331251PMC
March 2015

Cellular immunotherapy for refractory hematological malignancies.

J Transl Med 2013 Jun 19;11:150. Epub 2013 Jun 19.

Division of Hematology/Oncology, Rhode Island Hospital/The Miriam Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1186/1479-5876-11-150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689050PMC
June 2013

Addition of algenpantucel-L immunotherapy to standard adjuvant therapy for pancreatic cancer: a phase 2 study.

J Gastrointest Surg 2013 Jan 15;17(1):94-100; discussion p. 100-1. Epub 2012 Nov 15.

Department of Surgery, University Hospitals Seidman Cancer Center and Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1007/s11605-012-2064-6DOI Listing
January 2013

Dosimetric Feasibility of Dose Escalation Using SBRT Boost for Stage III Non-Small Cell Lung Cancer.

Front Oncol 2012 26;2:124. Epub 2012 Sep 26.

Department of Radiation Oncology, Rhode Island Hospital, Brown University Providence, RI, USA.

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http://dx.doi.org/10.3389/fonc.2012.00124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458262PMC
October 2012

Nonengraftment haploidentical cellular therapy for hematologic malignancies.

Adv Hematol 2012 18;2012:784213. Epub 2012 Jan 18.

Division of Hematology and Oncology, Rhode Island Hospital, The Warren Alpert Medical School, Providence, RI 02903, USA.

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http://dx.doi.org/10.1155/2012/784213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270515PMC
August 2012

Pathologic response after neoadjuvant carboplatin and weekly paclitaxel for early-stage lung cancer: a Brown University oncology group phase II study.

J Thorac Oncol 2011 Aug;6(8):1432-4

Brown University Oncology Group, Alpert Medical School of Brown University, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1097/JTO.0b013e3182209043DOI Listing
August 2011

Pneumonectomy after neoadjuvant chemotherapy and radiation for advanced-stage lung cancer.

Ann Surg Oncol 2010 Feb;17(2):476-82

Brown University Oncology Group, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1245/s10434-009-0810-0DOI Listing
February 2010

Phase I and pharmacokinetic study of gimatecan given orally once a week for 3 of 4 weeks in patients with advanced solid tumors.

Clin Cancer Res 2009 Jan;15(1):374-81

Massachusetts General Hospital, Dana-Farber/Harvard Cancer Center, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1024DOI Listing
January 2009

Pulmonary radiofrequency ablation: long-term safety and efficacy in 153 patients.

Radiology 2007 Apr;243(1):268-75

Department of Diagnostic Imaging, Brown Medical School/Rhode Island Hospital, Providence, RI 02903, USA.

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http://dx.doi.org/10.1148/radiol.2431060088DOI Listing
April 2007

HER family inhibitors in pancreatic cancer: current status and future directions.

Expert Opin Ther Targets 2007 Mar;11(3):337-47

The Brown University Oncology Group, 164 Summit Avenue, Providence, RI 02906, USA.

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http://dx.doi.org/10.1517/14728222.11.3.337DOI Listing
March 2007

Phase II trial of weekly paclitaxel and gemcitabine for previously untreated, stage IIIB-IV nonsmall cell lung cancer.

Cancer 2006 Sep;107(5):1050-4

Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84115, USA.

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http://dx.doi.org/10.1002/cncr.22095DOI Listing
September 2006

Multimodality treatment of esophageal cancer: a review of the current status and future directions.

Curr Oncol Rep 2006 May;8(3):174-82

Department of Medicine, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, USA.

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http://dx.doi.org/10.1007/s11912-006-0017-5DOI Listing
May 2006

Chemotherapy for pancreatic cancer.

Med Health R I 2004 May;87(5):132-4

Department of Medicine, Brown Medical School, USA.

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May 2004

Paclitaxel and concurrent radiation in upper gastrointestinal cancers.

Cancer Invest 2003 ;21(6):887-96

Brown University Oncology Group, Providence, Rhode Island, USA.

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http://dx.doi.org/10.1081/cnv-120025092DOI Listing
February 2004

Clinical research in pancreatic cancer: the Radiation Therapy Oncology Group trials.

Int J Radiat Oncol Biol Phys 2003 ;56(4 Suppl):31-7

Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/s0360-3016(03)00446-2DOI Listing
August 2003

Combined modality therapy for pancreatic cancer.

Semin Oncol 2003 Aug;30(4 Suppl 9):71-9

Brown University Oncology Group, Providence, RI, USA.

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http://dx.doi.org/10.1016/s0093-7754(03)00273-2DOI Listing
August 2003

Status of treatment for advanced gastric carcinoma.

Curr Oncol Rep 2003 May;5(3):210-8

Department of Medicine, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, USA.

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http://dx.doi.org/10.1007/s11912-003-0112-9DOI Listing
May 2003

ErbB2 degradation mediated by the co-chaperone protein CHIP.

J Biol Chem 2003 Apr 6;278(16):13829-37. Epub 2003 Feb 6.

Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M209640200DOI Listing
April 2003

A phase I study of a weekly schedule of paclitaxel and carboplatin in patients with advanced carcinoma.

Cancer 2002 Nov;95(9):2000-5

Department of Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, USA.

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http://dx.doi.org/10.1002/cncr.10902DOI Listing
November 2002

Gemcitabine, paclitaxel, and radiation for locally advanced pancreatic cancer: a Phase I trial.

Int J Radiat Oncol Biol Phys 2002 Sep;54(1):137-41

The Brown University Oncology Group, Department of Medicine, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, USA.

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http://dx.doi.org/10.1016/s0360-3016(02)02902-4DOI Listing
September 2002

Paclitaxel as a radiation sensitizer for locally advanced pancreatic cancer.

Crit Rev Oncol Hematol 2002 Jul;43(1):57-62

The Brown University Oncology Group, Department of Medicine, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906, USA.

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http://dx.doi.org/10.1016/s1040-8428(01)00184-6DOI Listing
July 2002

Human aspartyl (asparaginyl) beta-hydroxylase monoclonal antibodies: potential biomarkers for pancreatic carcinoma.

Pancreas 2002 Jul;25(1):39-44

Department of Medicine, Rhode Island Hospital, Brown University School of Medicine, Providence, Rhode Island 02903, USA.

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http://dx.doi.org/10.1097/00006676-200207000-00010DOI Listing
July 2002

Evaluation and treatment of hepatic metastases from unknown GI primary.

Med Health R I 2002 Jun;85(6):181-3

Department of Hematology/Oncology, The Miriam Hospital, 168 Summit Ave, Providence, RI 02908, USA.

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June 2002