Publications by authors named "Howard Riezman"

100Publications

HaloFlippers: A General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living Cells.

ACS Cent Sci 2020 Aug 20;6(8):1376-1385. Epub 2020 Jul 20.

School of Chemistry and Biochemistry and National Centre of Competence in Research (NCCR) Chemical Biology, University of Geneva, Geneva 1211, Switzerland.

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http://dx.doi.org/10.1021/acscentsci.0c00666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453570PMC
August 2020

Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway.

Curr Biol 2020 Oct 27;30(19):3775-3787.e7. Epub 2020 Aug 27.

NCCR Chemical Biology, Department of Biochemistry, University of Geneva, 1211 Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2020.07.059DOI Listing
October 2020

Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex.

Cell Chem Biol 2020 05 23;27(5):586-597.e12. Epub 2020 Apr 23.

Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2020.03.008DOI Listing
May 2020

Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in .

Mol Biol Cell 2019 10 11;30(22):2814-2826. Epub 2019 Sep 11.

NCCR Chemical Biology and Department of Biochemistry, University of Geneva, 1211 Geneva, Switzerland.

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https://www.molbiolcell.org/doi/10.1091/mbc.E19-07-0364
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http://dx.doi.org/10.1091/mbc.E19-07-0364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789163PMC
October 2019

Author Correction: Understanding the diversity of membrane lipid composition.

Nat Rev Mol Cell Biol 2019 Nov;20(11):715

Department of Biochemistry and National Centre for Competence in Research in Chemical Biology, Sciences II, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1038/s41580-019-0171-xDOI Listing
November 2019

Luciferase-Induced Photouncaging: Bioluminolysis.

Angew Chem Int Ed Engl 2019 11 20;58(45):16033-16037. Epub 2019 Sep 20.

School of Chemistry and Biochemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, 30 quai Ernest-Ansermet, Geneva, Switzerland.

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http://dx.doi.org/10.1002/anie.201907734DOI Listing
November 2019

On the road to unraveling the molecular functions of ether lipids.

FEBS Lett 2019 09 13;593(17):2378-2389. Epub 2019 Jun 13.

NCCR Chemical Biology, Department of Biochemistry, University of Geneva, Switzerland.

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http://dx.doi.org/10.1002/1873-3468.13465DOI Listing
September 2019

Vesicular and non-vesicular lipid export from the ER to the secretory pathway.

Biochim Biophys Acta Mol Cell Biol Lipids 2020 01 2;1865(1):158453. Epub 2019 May 2.

Department of Cell Biology, University of Seville, 41012 Seville, Spain; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2019.04.013DOI Listing
January 2020

Sphingolipids and membrane targets for therapeutics.

Curr Opin Chem Biol 2019 06 18;50:19-28. Epub 2019 Mar 18.

Department of Organic Chemistry, NCCR Chemical Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1205 Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cbpa.2019.02.015DOI Listing
June 2019

Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures.

Chem Sci 2019 Feb 26;10(8):2253-2258. Epub 2018 Dec 26.

Department of Biochemistry , NCCR Chemical Biology , University of Geneva , Quai Ernest-Ansermet 30 , 1211 , Geneva , Switzerland . Email:

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http://dx.doi.org/10.1039/c8sc03614dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385812PMC
February 2019

A Chemogenetic Approach for the Optical Monitoring of Voltage in Neurons.

Angew Chem Int Ed Engl 2019 02 25;58(8):2341-2344. Epub 2019 Jan 25.

Molecular Medicine Partnership Unit (MMPU), 69117, Heidelberg, Germany.

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http://dx.doi.org/10.1002/anie.201812967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391943PMC
February 2019

Lysophospholipids Facilitate COPII Vesicle Formation.

Curr Biol 2018 06 7;28(12):1950-1958.e6. Epub 2018 Jun 7.

Department of Biochemistry, University of Geneva, 1211 Geneva, Switzerland; Swiss National Centre for Competence in Research in Chemical Biology, 1211 Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2018.04.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013297PMC
June 2018

Understanding the diversity of membrane lipid composition.

Nat Rev Mol Cell Biol 2018 05 7;19(5):281-296. Epub 2018 Feb 7.

Department of Biochemistry and National Centre for Competence in Research in Chemical Biology, Sciences II, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1038/nrm.2017.138DOI Listing
May 2018

mTORC2 Promotes Tumorigenesis via Lipid Synthesis.

Cancer Cell 2017 Dec;32(6):807-823.e12

Biozentrum, University of Basel, 4056 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.11.011DOI Listing
December 2017

Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites.

Mitochondrion 2018 03 1;39:51-59. Epub 2017 Sep 1.

KU Leuven - University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Laboratory of Cell Metabolism, B-3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2017.08.013DOI Listing
March 2018

Membrane Phosphoproteomics of Yeast Early Response to Acetic Acid: Role of Hrk1 Kinase and Lipid Biosynthetic Pathways, in Particular Sphingolipids.

Front Microbiol 2017 12;8:1302. Epub 2017 Jul 12.

Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, Universidade de LisboaLisbon, Portugal.

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http://dx.doi.org/10.3389/fmicb.2017.01302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506226PMC
July 2017

Detection of genome-edited mutant clones by a simple competition-based PCR method.

PLoS One 2017 6;12(6):e0179165. Epub 2017 Jun 6.

Department of Biochemistry and NCCR Chemical Biology, Sciences II, University of Geneva, Geneva, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179165PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460891PMC
September 2017

Structure and conserved function of iso-branched sphingoid bases from the nematode .

Chem Sci 2017 May 6;8(5):3676-3686. Epub 2017 Mar 6.

Department of Biochemistry , University of Geneva , CH-1205 Geneva , Switzerland . Email:

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http://xlink.rsc.org/?DOI=C6SC04831E
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http://dx.doi.org/10.1039/c6sc04831eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094178PMC
May 2017

Making Sense of the Yeast Sphingolipid Pathway.

J Mol Biol 2016 12 21;428(24 Pt A):4765-4775. Epub 2016 Sep 21.

Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.

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http://dx.doi.org/10.1016/j.jmb.2016.09.010DOI Listing
December 2016

A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolism.

Metab Eng 2016 09 23;37:46-62. Epub 2016 Apr 23.

Laboratory of Computational Systems Biology, Department of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2016.04.002DOI Listing
September 2016

D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage.

J Biomed Opt 2016 Jun;21(6):61003

University of California, Irvine, Department of Chemistry, Irvine, California 92697, United States.

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http://dx.doi.org/10.1117/1.JBO.21.6.061003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681884PMC
June 2016

Intracellular sphingosine releases calcium from lysosomes.

Elife 2015 Nov 27;4. Epub 2015 Nov 27.

Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.7554/eLife.10616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744193PMC
November 2015

Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surface.

J Lipid Res 2016 Mar 8;57(3):352-60. Epub 2015 Oct 8.

National Centre of Competence in Research (NCCR) Chemical Biology, Department of Biochemistry, University of Geneva, Geneva, Switzerland.

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http://www.jlr.org/lookup/doi/10.1194/jlr.R062760
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http://dx.doi.org/10.1194/jlr.R062760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767001PMC
March 2016

LAPTM4B facilitates late endosomal ceramide export to control cell death pathways.

Nat Chem Biol 2015 Oct 17;11(10):799-806. Epub 2015 Aug 17.

Department of Anatomy, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/nchembio.1889DOI Listing
October 2015

Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour.

Nature 2015 Jul 25;523(7558):88-91. Epub 2015 May 25.

Faculty of Sciences, Institute of Molecular Life Sciences, University of Zurich, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1038/nature14429DOI Listing
July 2015

The SwissLipids knowledgebase for lipid biology.

Bioinformatics 2015 Sep 5;31(17):2860-6. Epub 2015 May 5.

Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, CMU, 1 rue Michel-Servet, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1093/bioinformatics/btv285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547616PMC
September 2015

Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae.

Mol Biol Cell 2015 May 11;26(9):1601-15. Epub 2015 Mar 11.

Center for Molecular Biology of the University of Heidelberg (ZMBH) and German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1091/mbc.E14-11-1559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436773PMC
May 2015

COPII coat composition is actively regulated by luminal cargo maturation.

Curr Biol 2015 Jan 31;25(2):152-162. Epub 2014 Dec 31.

Department of Cell Biology, University of Seville, 41012 Seville, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2014.11.039DOI Listing
January 2015

HCV 3a core protein increases lipid droplet cholesteryl ester content via a mechanism dependent on sphingolipid biosynthesis.

PLoS One 2014 18;9(12):e115309. Epub 2014 Dec 18.

Division of Clinical Pathology, University Hospital, University of Geneva School of Medicine, Geneva, Switzerland; Divisions of Gastroenterology and Hepatology, University Hospital, University of Geneva School of Medicine, Geneva, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115309PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270764PMC
December 2015

Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis.

Mol Biol Cell 2014 Oct 20;25(20):3234-46. Epub 2014 Aug 20.

Department of Biochemistry, University of Geneva, Geneva CH-1211, Switzerland National Centre of Competence in Research "Chemical Biology,", University of Geneva, Geneva CH-1211, Switzerland

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http://dx.doi.org/10.1091/mbc.E14-03-0851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196872PMC
October 2014

Synthetic multivalent antifungal peptides effective against fungi.

PLoS One 2014 3;9(2):e87730. Epub 2014 Feb 3.

Singapore Eye Research Institute, Singapore, Singapore ; Department of Neuroscience and Behavioural Disorders, Duke-NUS Graduate Medical School, Singapore, Singapore ; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087730PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912015PMC
October 2014

A fluorogenic probe for SNAP-tagged plasma membrane proteins based on the solvatochromic molecule Nile Red.

ACS Chem Biol 2014 Mar 29;9(3):606-12. Epub 2014 Jan 29.

École Polytechnique Fédérale de Lausanne (EPFL) , Institute of Chemical Sciences and Engineering, National Centre of Competence in Research (NCCR) in Chemical Biology, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1021/cb400819cDOI Listing
March 2014

Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast.

J Cell Sci 2014 Jan 8;127(Pt 2):376-87. Epub 2013 Nov 8.

Department of Biofunctional Science and Technology, Graduate School of Biosphere Science, Hiroshima University, Hiroshima 739-8528, Japan.

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http://dx.doi.org/10.1242/jcs.132001DOI Listing
January 2014

Sphingolipid homeostasis in the web of metabolic routes.

Biochim Biophys Acta 2014 May 1;1841(5):647-56. Epub 2013 Nov 1.

Department of Biochemistry and NCCR Chemical Biology, University of Geneva, CH-1211 Geneva 4, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2013.10.014DOI Listing
May 2014

The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium-chain fatty acids.

Cell Rep 2013 Oct 26;5(1):248-58. Epub 2013 Sep 26.

Center for Integrative Genomics, University of Lausanne, Lausanne 1015, Switzerland.

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http://dx.doi.org/10.1016/j.celrep.2013.08.032DOI Listing
October 2013

Dynamic amphiphile libraries to screen for the "fragrant" delivery of siRNA into HeLa cells and human primary fibroblasts.

J Am Chem Soc 2013 Jun 14;135(25):9295-8. Epub 2013 Jun 14.

School of Chemistry and Biochemistry, National Centre of Competence in Research (NCCR) Chemical Biology, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1021/ja404153mDOI Listing
June 2013

Sphingolipid signaling in yeast: potential implications for understanding disease.

Front Biosci (Elite Ed) 2013 Jan 1;5:97-108. Epub 2013 Jan 1.

Department of Biochemistry, University of Geneva, Sciences II, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.2741/e599DOI Listing
January 2013

Yeast as a model system for studying lipid homeostasis and function.

FEBS Lett 2012 Aug 21;586(18):2858-67. Epub 2012 Jul 21.

Department of Biochemistry, University of Geneva, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1016/j.febslet.2012.07.033DOI Listing
August 2012

Rsp5 ubiquitin ligase is required for protein trafficking in Saccharomyces cerevisiae COPI mutants.

PLoS One 2012 26;7(6):e39582. Epub 2012 Jun 26.

Department of Genetics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039582PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383674PMC
March 2013

Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels.

J Lipid Res 2012 Aug 24;53(8):1522-34. Epub 2012 May 24.

Department of Biochemistry, NCCR Chemical Biology, University of Geneva, CH-1211 Geneva, Switzerland.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M025692
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http://dx.doi.org/10.1194/jlr.M025692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540855PMC
August 2012

An essential function of sphingolipids in yeast cell division.

Mol Microbiol 2012 Jun 23;84(6):1018-32. Epub 2012 May 23.

Department of Biochemistry and NCCR Chemical Biology, University of Geneva, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1111/j.1365-2958.2012.08087.xDOI Listing
June 2012

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis.

Nat Cell Biol 2012 Apr 15;14(5):542-7. Epub 2012 Apr 15.

Max Planck Institute of Biochemistry, Organelle Architecture and Dynamics, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1038/ncb2480DOI Listing
April 2012

Amphiphilic dynamic NDI and PDI probes: imaging microdomains in giant unilamellar vesicles.

Org Biomol Chem 2012 Aug 13;10(30):6087-93. Epub 2012 Apr 13.

School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland.

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http://www.rsc.org/suppdata/ob/c2/c2ob25119a/c2ob25119a.pdf
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http://xlink.rsc.org/?DOI=c2ob25119a
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http://dx.doi.org/10.1039/c2ob25119aDOI Listing
August 2012

Conceptually new entries into cells.

Chimia (Aarau) 2011 ;65(11):853-8

School of Chemistry and Biochemistry, University of Geneva, CH-1211 Geneva, Switzerland.

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http://dx.doi.org/10.2533/chimia.2011.853DOI Listing
February 2012

Chemical biology approaches to membrane homeostasis and function.

Chimia (Aarau) 2011 ;65(11):849-52

Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.2533/chimia.2011.849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289194PMC
February 2012

Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae.

PLoS One 2011 14;6(12):e28344. Epub 2011 Dec 14.

Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028344PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237449PMC
August 2012

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

Hum Mol Genet 2012 Feb 28;21(3):586-608. Epub 2011 Oct 28.

Cellular & Molecular Pathology, German Cancer Research Center, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/hmg/ddr494DOI Listing
February 2012

Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thaliana.

New Phytol 2011 Dec 22;192(4):841-54. Epub 2011 Aug 22.

Department of Plant Biochemistry, Albrecht von Haller Institute for Plant Sciences, Georg August University, D-37077 Göttingen, Germany.

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http://dx.doi.org/10.1111/j.1469-8137.2011.03852.xDOI Listing
December 2011

A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance.

Metab Eng 2011 Sep 30;13(5):555-69. Epub 2011 Jun 30.

Department of Biochemistry, University of Geneva, 30 Quai Ernest Ansermet, CH-1211 Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.ymben.2011.06.006DOI Listing
September 2011

Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI.

J Cell Biol 2011 Jul 4;194(1):61-75. Epub 2011 Jul 4.

Research Institute for Microbial Diseases and WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1083/jcb.201012074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135397PMC
July 2011

Distribution and functions of sterols and sphingolipids.

Cold Spring Harb Perspect Biol 2011 May 1;3(5). Epub 2011 May 1.

Department of Biochemistry, University of Geneva, Geneva 4, Switzerland.

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http://dx.doi.org/10.1101/cshperspect.a004762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101845PMC
May 2011

An efficient method for the production of isotopically enriched cholesterol for NMR.

J Lipid Res 2011 May 26;52(5):1062-5. Epub 2011 Feb 26.

Department of Organic Chemistry, University of Geneva, 1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1194/jlr.D014209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073474PMC
May 2011

Two pathways of sphingolipid biosynthesis are separated in the yeast Pichia pastoris.

J Biol Chem 2011 Apr 8;286(13):11401-14. Epub 2011 Feb 8.

Department of Plant Biochemistry, Albrecht von Haller Institute for Plant Sciences, Georg August University, Göttingen, Germany.

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http://dx.doi.org/10.1074/jbc.M110.193094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064196PMC
April 2011

Yeast lipid analysis and quantification by mass spectrometry.

Methods Enzymol 2010 1;470:369-91. Epub 2010 Mar 1.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1016/S0076-6879(10)70015-XDOI Listing
January 2011

Survival strategies of a sterol auxotroph.

Development 2010 Nov;137(21):3675-85

Max-Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse-108, 01307 Dresden, Germany.

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http://dx.doi.org/10.1242/dev.044560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964098PMC
November 2010

Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism.

Structure 2010 Aug;18(8):1054-65

Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.

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http://linkinghub.elsevier.com/retrieve/pii/S096921261000224
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http://dx.doi.org/10.1016/j.str.2010.05.011DOI Listing
August 2010

Concentration of GPI-anchored proteins upon ER exit in yeast.

Traffic 2009 Feb 20;10(2):186-200. Epub 2008 Nov 20.

Department of Biochemistry, University of Geneva, Sciences II, 30 quai Ernest Ansermet, CH-1211 Geneva, Switzerland.

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http://doi.wiley.com/10.1111/j.1600-0854.2008.00857.x
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http://dx.doi.org/10.1111/j.1600-0854.2008.00857.xDOI Listing
February 2009

Identifying key residues of sphinganine-1-phosphate lyase for function in vivo and in vitro.

J Biol Chem 2008 Jul 17;283(29):20159-69. Epub 2008 May 17.

Department of Biochemistry, University of Geneva, Geneva 4, Switzerland.

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http://dx.doi.org/10.1074/jbc.M709753200DOI Listing
July 2008

The presence of an ER exit signal determines the protein sorting upon ER exit in yeast.

Biochem J 2008 Sep;414(2):237-45

Department of Biochemistry, University of Geneva, Sciences II, 30 quai Ernest Ansermet, CH-1211 Geneva, Switzerland.

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http://dx.doi.org/10.1042/BJ20080715DOI Listing
September 2008

Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membrane.

J Cell Biol 2008 Mar 17;180(6):1219-32. Epub 2008 Mar 17.

Instituto de Biología Molecular de Barcelona, Consejo Superior de Investigaciones Científicas, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1083/jcb.200708060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290847PMC
March 2008

The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus.

J Cell Biol 2008 Feb 18;180(4):713-20. Epub 2008 Feb 18.

Department of Cell Biology. University of Seville, 41012 Seville, Spain.

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http://dx.doi.org/10.1083/jcb.200710025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265561PMC
February 2008

Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane.

J Biol Chem 2008 Mar 29;283(10):6393-401. Epub 2007 Dec 29.

Department Biochemistry of Membranes, Bijvoet Center, Institute of Biomembranes, Utrecht University, Utrecht, The Netherlands.

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March 2008

The long and short of fatty acid synthesis.

Authors:
Howard Riezman

Cell 2007 Aug;130(4):587-8

Department of Biochemistry, University of Geneva, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1016/j.cell.2007.08.008DOI Listing
August 2007

Proteasome-independent functions of ubiquitin in endocytosis and signaling.

Science 2007 Jan;315(5809):201-5

Department of Biochemistry, University of Geneva, 30 Quai Ernest Ansermet, CH-1211 Geneva, Switzerland.

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http://dx.doi.org/10.1126/science.1127085DOI Listing
January 2007

Transmembrane topology of ceramide synthase in yeast.

Biochem J 2006 Sep;398(3):585-93

Department of Biochemistry, University of Geneva, Sciences II, 30, quai E. Ansermet, CH-1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1042/BJ20060697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559446PMC
September 2006

Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae.

Mol Biol Cell 2006 Mar 28;17(3):1164-75. Epub 2005 Dec 28.

Department of Biochemistry, Biozentrum of the University of Basel, CH-4056 Basel, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382306PMC
March 2006