Publications

Gray matter regions statistically mediating the cross-sectional association of eotaxin and set-shifting among older adults with major depressive disorder.
Int J Geriatr Psychiatry 2017 Dec 19;32(12):1226-1232. Epub 2016 Sep 19.
Department of Psychiatry, Western Psychiatric Institute and Clinic of University of Pittsburgh Medical Center, Pittsburgh, PA, USA.


Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults.
Neurobiol Aging 2017 Sep 6;57:153-161. Epub 2017 Jun 6.
Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada; Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Hip Health and Mobility, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.

Slowing gait and risk for cognitive impairment: The hippocampus as a shared neural substrate.
Neurology 2017 Jul 28;89(4):336-342. Epub 2017 Jun 28.
From the Department of Epidemiology (A.L.R., A.L.M., R.M.B., C.R.), School of Public Health, and Departments of Psychiatry and Bioengineering (H.J.A.), University of Pittsburgh, PA; Department of Neurology and Medicine (J.V.), Albert Einstein College of Medicine, Bronx, NY; Sticht Center for Healthy Aging and Alzheimer's Prevention (S.B.K.), Wake Forest School of Medicine, Winston-Salem, NC; Laboratory of Epidemiology and Population Sciences (T.B.H.), IRP, National Institute on Aging, NIH, Bethesda, MD; Departments of Psychiatry, Neurology, and Epidemiology (K.Y.), University of California, San Francisco; Department of Preventive Medicine (S. Satterfield), University of Tennessee Health Science Center, Memphis; and Longitudinal Studies Section (S. Studenski), National Institute on Aging, Baltimore, MD.

Immunological biomarkers associated with brain structure and executive function in late-life depression: exploratory pilot study.
Int J Geriatr Psychiatry 2017 Jun 10;32(6):692-699. Epub 2016 Jun 10.
Healthy Mind Lab, Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.

Regional Gray Matter Volumes as Related to Psychomotor Slowing in Adults with Type 1 Diabetes.
Psychosom Med 2017 Jun;79(5):533-540
From the Department of Epidemiology, University of Pittsburgh Graduate School of Public Health (Nunley, Orchard, Rosano), Pittsburgh, PA; Human Research Protection Program, University of California San Francisco (Ryan), San Francisco, CA; Departments of Psychology and Psychiatry, University of Pittsburgh (Jennings); and Department of Psychiatry, School of Medicine, University of Pittsburgh (Aizenstein, MacCloud), Pittsburgh, PA.

Physical activity and hippocampal volume in middle-aged patients with type 1 diabetes.
Neurology 2017 Apr 10;88(16):1564-1570. Epub 2017 Mar 10.
From the Department of Epidemiology, Graduate School of Public Health (K.A.N., T.J.O., T.C., C.R.), Department of Psychology (R.L.L., J.R.J., K.I.E.), and Department of Psychiatry, School of Medicine (H.J.A., J.R.J.), University of Pittsburgh, PA.



The effects of white matter disease on the accuracy of automated segmentation.
Psychiatry Res 2016 Jul 19;253:7-14. Epub 2016 May 19.
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Biostatistics, Graduate School of Public Health, Pittsburgh, PA, USA. Electronic address:


Predictors and Moderators of Remission With Aripiprazole Augmentation in Treatment-Resistant Late-Life Depression: An Analysis of the IRL-GRey Randomized Clinical Trial.
JAMA Psychiatry 2016 Apr;73(4):329-36
Department of Psychiatry, Western Psychiatric Institute and Clinic of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania12Department of Behavioral and Community Health Sciences, Graduate School of Public Health, University of Pittsburgh, Pi.

Menopausal hot flashes and white matter hyperintensities.
Menopause 2016 Jan;23(1):27-32
1Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 2Department of Neurology, Albert Einstein College of Medicine, Bronx, NY 3Department of Electrical and Computer Engineering, University of Pittsburgh, Pittsburgh, PA 4Department of Psychiatry, University of Illinois at Chicago, Chicago, IL.

Age of Childhood Onset in Type 1 Diabetes and Functional Brain Connectivity in Midlife.
Psychosom Med 2015 Jul-Aug;77(6):622-30
From the Departments of Psychiatry (J.P. Ryan, Aizenstein, C.M. Ryan, Fine) and Neurology (Saxton), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and Departments of Epidemiology (Orchard) and Epidemiology (Nunley, Rosano), University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.



White matter hyperintensities in middle-aged adults with childhood-onset type 1 diabetes.
Neurology 2015 May 22;84(20):2062-9. Epub 2015 Apr 22.
From the Department of Epidemiology, Graduate School of Public Health (K.A.N., T.J.O., J.C.Z., R.M.B., T.C., R.G.M., C.R.) and Department of Psychiatry, School of Medicine (C.M.R., H.J.A., J.R.J., J.R.), University of Pittsburgh, Pittsburgh, PA; and VeraLight Inc. (J.D.M.), Albuquerque, NM.

Multimodal MRI markers support a model of small vessel ischemia for depressive symptoms in very old adults.
Psychiatry Res 2014 Nov 23;224(2):73-80. Epub 2014 Aug 23.
Geriatric Psychiatric Neuroimaging, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, USA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

Amyloid, neurodegeneration, and small vessel disease as predictors of dementia in the oldest-old.
Neurology 2014 Nov 10;83(20):1804-11. Epub 2014 Oct 10.
From the Departments of Neurology (O.L.L., J.T.B., B.S., M.I., E.M.), Psychiatry (O.L.L., W.E.K., J.T.B., H.J.A.), Radiology (C.M., R.L.C., J.P., A.C.), Pharmaceutical Sciences (C.M.), Psychology (J.T.B.), Biostatistics (L.W.), and Epidemiology, Graduate School of Public Health (L.H.K.), University of Pittsburgh, School of Medicine, PA; and Department of Neurology (S.T.D.), University of Virginia School of Medicine, Charlottesville.

Frontal gray matter atrophy in middle aged adults with type 1 diabetes is independent of cardiovascular risk factors and diabetes complications.
J Diabetes Complications 2013 Nov-Dec;27(6):558-64. Epub 2013 Aug 30.
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

Aging, the central nervous system, and mobility.
J Gerontol A Biol Sci Med Sci 2013 Nov 10;68(11):1379-86. Epub 2013 Jul 10.
Center for Aging and Population Health, Graduate School of Public Health, 130 North Bellefield Street, Room 507, Pittsburgh, PA 15213.

Pulse wave velocity is associated with β-amyloid deposition in the brains of very elderly adults.
Neurology 2013 Nov 16;81(19):1711-8. Epub 2013 Oct 16.
From the Department of Epidemiology, Graduate School of Public Health (T.M.H., L.H.K., E.J.M.B.-M., R.H.M.), and the Departments of Neurology (E.M.M., B.E.S., O.L.L.), Psychiatry (W.E.K., H.J.A., A.D.C.), and Radiology (C.A.M.), School of Medicine, University of Pittsburgh, PA; and the Office of the Dean and Department of Neurology (S.T.D.), School of Medicine, University of Virginia, Charlottesville.






fMRI activation in late-life anxious depression: a potential biomarker.
Int J Geriatr Psychiatry 2009 Aug;24(8):820-8
Department of Psychiatry, The Advanced Center in Interventions and Services Research for Late-Life Mood Disorders, University of Pittsburgh School of Medicine and the John A. Hartford Center of Excellence in Geriatric Psychiatry, Pittsburgh, PA, USA.

Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease.
Proc Natl Acad Sci U S A 2009 Apr 3;106(16):6820-5. Epub 2009 Apr 3.
Banner Alzheimer's Institute and the Positron Emission Tomography Center, Good Samaritan Regional Medical Center, Phoenix, AZ 85006, USA.

Altered functioning of the executive control circuit in late-life depression: episodic and persistent phenomena.
Am J Geriatr Psychiatry 2009 Jan;17(1):30-42
Department of Psychiatry, University of Pittsburgh, and Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

OF