Dr. Howard Casey Cromwell, PhD - Bowling Green State University - Associate Professor

Dr. Howard Casey Cromwell

PhD

Bowling Green State University

Associate Professor

Bowling Green, Ohio | United States

Main Specialties: Addiction Psychiatry, Biology, Neuropathology

Additional Specialties: Neuroscience

ORCID logohttps://orcid.org/0000-0003-0464-7082


Top Author

Dr. Howard Casey Cromwell, PhD - Bowling Green State University - Associate Professor

Dr. Howard Casey Cromwell

PhD

Introduction

Dr. Cromwell has worked on the brain basis of motivation since his graduate studies at the University of Michigan. Currently, the lab is interested in studying the neural basis of reward relativity and especially how neurons show rapid plasticity that is involved in updating reward value information. The best paradigm to explore this question is the incentive contrast paradigm. It offers a way to compare new valuation to a reference that is experimentally controlled and vary value shifts in a parametric fashion. Once animals become engaged in reward valuation, their brains will show sensitivity to these shifts in rapid and dynamic fashion.

Primary Affiliation: Bowling Green State University - Bowling Green, Ohio , United States

Specialties:

Additional Specialties:

Research Interests:


View Dr. Howard Casey Cromwell’s Resume / CV

Education

Jun 2017
Uni Michigan
PhD
warm August day in Ann Arbor
Jun 2017
Uni Michigan
PhD
warm August day in Ann Arbor
Jun 2017
Uni Michigan
PhD
warm August day in Ann Arbor
University of Michigan
PhD
Psychology

Experience

Jun 2017
Assistant Researcher
Monkey Trainer
Bowling Green State University
Faculty
PSychology

Publications

39Publications

362Reads

1071Profile Views

539PubMed Central Citations

Jaak Panksepp (1943-2017).

Am Psychol 2018 Feb-Mar;73(2):202

Bowling Green State University.

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http://dx.doi.org/10.1037/amp0000228DOI Listing
April 2019
4 Reads

A possible social relative reward effect: Influences of outcome inequity between rats during operant responding.

Behav Processes 2018 Dec 7;157:459-469. Epub 2018 Jul 7.

Department of Psychology and John Paul Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH, 43403, United States. Electronic address:

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http://dx.doi.org/10.1016/j.beproc.2018.06.016DOI Listing
December 2018
20 Reads
1.570 Impact Factor

Neural encoding of choice during a delayed response task in primate striatum and orbitofrontal cortex.

Exp Brain Res 2018 06 2;236(6):1679-1688. Epub 2018 Apr 2.

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3DY, UK.

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http://dx.doi.org/10.1007/s00221-018-5253-zDOI Listing
June 2018
15 Reads
2.040 Impact Factor

Striatal Activity and Reward Relativity: Neural Signals Encoding Dynamic Outcome Valuation.

eNeuro 2016 Sep-Oct;3(5). Epub 2016 Nov 1.

Department of Psychology, Bowling Green State University, Bowling Green, Ohio 43403; J.P. Scott Center for Neuroscience, Mind & Behavior, Bowling Green State University, Bowling Green, Ohio 43403.

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http://dx.doi.org/10.1523/ENEURO.0022-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089537PMC
October 2017
20 Reads
1 Citation

Effects of anandamide administration on components of reward processing during free choice.

Pharmacol Biochem Behav 2017 07 18;158:14-21. Epub 2017 May 18.

Department of Psychology, John Paul Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, United States. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2017.05.008DOI Listing
July 2017
40 Reads
2.781 Impact Factor

Effects of striatal lesions on components of choice: Reward discrimination, preference, and relative valuation.

Behav Brain Res 2016 12 17;315:130-40. Epub 2016 Aug 17.

J.P. Scott Center for Neuroscience, Mind and Behavior and Department of Psychology, Bowling Green State University, Bowling Green OH, 43403, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2016.08.031DOI Listing
December 2016
11 Reads
1 Citation
3.030 Impact Factor

Striatal Activity and Reward Relativity: Neural

eNEURO 2016, 3(5) e0022-16.2016 1–21

eNEURO

The striatum is a key brain region involved in reward processing. Striatal activity has been linked to encoding reward magnitude and integrating diverse reward outcome information. Recent work has supported the involvement of striatum in the valuation of outcomes. The present work extends this idea by examining striatal activity during dynamic shifts in value that include different levels and directions of magnitude disparity. A novel task was used to produce diverse relative reward effects on a chain of instrumental action. Rats (Rattus norvegicus) were trained to respond to cues associated with specific outcomes varying by food pellet magnitude. Animals were exposed to single-outcome sessions followed by mixed-outcome sessions, and neural activity was compared among identical outcome trials from the different behavioral contexts. Results recording striatal activity show that neural responses to different task elements reflect incentive contrast as well as other relative effects that involve generalization between outcomes or possible influences of outcome variety. The activity that was most prevalent was linked to food consumption and post-food consumption periods. Relative encoding was sensitive to magnitude disparity. A within-session analysis showed strong contrast effects that were dependent upon the outcome received in the immediately preceding trial. Significantly higher numbers of responses were found in ventral striatum linked to relative outcome effects. Our results support the idea that relative value can incorporate diverse relationships, including comparisons from specific individual outcomes to general behavioral contexts. The striatum contains these diverse relative processes, possibly enabling both a higher information yield concerning value shifts and a greater behavioral flexibility.

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October 2016
9 Reads

Fractionating choice: A study on reward discrimination, preference, and relative valuation in the rat (Rattus norvegicus).

J Comp Psychol 2016 May 14;130(2):174-86. Epub 2016 Apr 14.

J.P. Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University.

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http://dx.doi.org/10.1037/com0000034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873358PMC
May 2016
9 Reads
1 Citation

Relative reward effects on operant behavior: Incentive contrast, induction and variety effects.

Behav Processes 2015 Jul 12;116:87-99. Epub 2015 May 12.

Department of Psychology and J.P. Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA. Electronic address:

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http://dx.doi.org/10.1016/j.beproc.2015.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458168PMC
July 2015
5 Reads
4 Citations
1.570 Impact Factor

Influence of emotional states on inhibitory gating: animals models to clinical neurophysiology.

Behav Brain Res 2015 Jan 23;276:67-75. Epub 2014 May 23.

Department of Psychology and J.P. Scott Center for Neuroscience, Mind and Behavior at Bowling Green State University, Bowling Green, OH 43403, United States.

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http://dx.doi.org/10.1016/j.bbr.2014.05.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241394PMC
January 2015
8 Reads
3 Citations
3.030 Impact Factor

Perinatal exposure to polychlorinated biphenyls alters social behaviors in rats.

Toxicol Lett 2010 Nov 9;199(2):136-43. Epub 2010 Sep 9.

Department of Biological Sciences, Bowling Green State University, Bowling Green, OH 43403-0208, USA.

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http://dx.doi.org/10.1016/j.toxlet.2010.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139010PMC
November 2010
9 Reads
18 Citations
3.262 Impact Factor

The effects of prenatal stress on motivation in the rat pup.

Stress 2009 May;12(3):250-8

Department of Psychology and JP Scott Center for Neuroscience, Mind and Behavior, Bowling Green State University, Bowling Green, OH 43403, USA.

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http://dx.doi.org/10.1080/10253890802367265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137965PMC
May 2009
6 Reads
6 Citations
2.715 Impact Factor

Reduction of prelimbic inhibitory gating of auditory evoked potentials after fear conditioning.

Behav Neurosci 2009 Apr;123(2):315-27

Department of Psychiatry and Brain Research and Imaging Neuroscience, Wayne State University School of Medicine, USA.

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http://dx.doi.org/10.1037/a0014364DOI Listing
April 2009
10 Reads
3 Citations
2.730 Impact Factor

The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats.

Dev Psychobiol 2009 Jan;51(1):34-46

Department of Biomedical Engineering, Falk Center for Molecular Therapeutics, Northwestern University, 1801 Maple Ave., Suite 4300, Evanston, IL 60201, USA.

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http://dx.doi.org/10.1002/dev.20343DOI Listing
January 2009
24 Reads
22 Citations
3.310 Impact Factor

Sensory gating: a translational effort from basic to clinical science.

Clin EEG Neurosci 2008 Apr;39(2):69-72

Department of Psychology, Bowling Green State University, Ohio 43403, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127047PMC
http://dx.doi.org/10.1177/155005940803900209DOI Listing
April 2008
17 Reads
25 Citations
3.160 Impact Factor

Effects of polychlorinated biphenyls on maternal odor conditioning in rat pups.

Physiol Behav 2007 Aug 1;91(5):658-66. Epub 2007 Apr 1.

Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA.

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http://dx.doi.org/10.1016/j.physbeh.2007.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138982PMC
August 2007
8 Reads
9 Citations
2.980 Impact Factor

Single unit and population responses during inhibitory gating of striatal activity in freely moving rats.

Neuroscience 2007 Apr 22;146(1):69-85. Epub 2007 Feb 22.

Department of Psychology and The J. P. Scott Center for Neuroscience, Mind and Behavior at Bowling Green State University, Psychology Building, Bowling Green, OH 43403, USA.

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http://dx.doi.org/10.1016/j.neuroscience.2007.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127048PMC
April 2007
10 Reads
10 Citations
3.360 Impact Factor

Inhibitory gating of single unit activity in amygdala: effects of ketamine, haloperidol, or nicotine.

Biol Psychiatry 2007 Apr 19;61(7):880-9. Epub 2006 Oct 19.

Department of Physiology and Pharmacology, School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.06.037DOI Listing
April 2007
9 Reads
12 Citations
10.260 Impact Factor

Auditory inhibitory gating in medial prefrontal cortex: Single unit and local field potential analysis.

Neuroscience 2006 Aug 3;141(1):47-65. Epub 2006 May 3.

Department of Psychology and the J.P. Scott Center for Neuroscience, Mind and Behavior, Psychology Building, Bowling Green State University, Bowling Green, OH 43403, USA.

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http://dx.doi.org/10.1016/j.neuroscience.2006.03.040DOI Listing
August 2006
13 Reads
15 Citations
3.360 Impact Factor

Relative reward processing in primate striatum.

Exp Brain Res 2005 May 8;162(4):520-5. Epub 2005 Mar 8.

Institute of Physiology, University of Fribourg, 1700 Fribourg, Switzerland.

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http://dx.doi.org/10.1007/s00221-005-2223-zDOI Listing
May 2005
9 Reads
39 Citations
2.040 Impact Factor

Auditory inhibitory gating in the amygdala: single-unit analysis in the behaving rat.

Brain Res 2005 May;1043(1-2):12-23

Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.brainres.2005.01.106DOI Listing
May 2005
7 Reads
13 Citations
2.843 Impact Factor

Effect of baclofen on alcohol and sucrose self-administration in rats.

Alcohol Clin Exp Res 2003 Jun;27(6):900-8

Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1097/01.ALC.0000071744.78580.78DOI Listing
June 2003
7 Reads
21 Citations
3.210 Impact Factor

Effects of expectations for different reward magnitudes on neuronal activity in primate striatum.

J Neurophysiol 2003 May 29;89(5):2823-38. Epub 2003 Jan 29.

Institute of Physiology, University of Fribourg, Switzerland.

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http://dx.doi.org/10.1152/jn.01014.2002DOI Listing
May 2003
5 Reads
102 Citations
2.890 Impact Factor

Behavioral reactions reflecting differential reward expectations in monkeys.

Exp Brain Res 2001 Oct;140(4):511-8

Department of Psychology, Tokyo Metropolitan Institute for Neuroscience, 2-6 Musashidai, Fuchu, Tokyo, 183-0042, Japan.

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http://dx.doi.org/10.1007/s002210100856DOI Listing
October 2001
6 Reads
29 Citations
2.040 Impact Factor

Influence of expectation of different rewards on behavior-related neuronal activity in the striatum.

J Neurophysiol 2001 Jun;85(6):2477-89

Institute of Physiology, University of Fribourg, CH-1700 Fribourg, Switzerland.

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http://dx.doi.org/10.1152/jn.2001.85.6.2477DOI Listing
June 2001
2 Reads
61 Citations
2.890 Impact Factor

Acetylcholine receptor activation enhances NMDA-mediated responses in the rat neostriatum.

Neurophysiol Clin 1999 Dec;29(6):482-9

Institute of Human Physiology, Palermo University, Italy.

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December 1999
1 Read
1.463 Impact Factor

Dopaminergic and glutamatergic interactions in the expression of self-injurious behavior.

Dev Neurosci 1998 ;20(2-3):180-7

UCLA Neuropsychiatric Institute, Los Angeles, CA 90024-1759, USA.

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http://dx.doi.org/10.1159/000017312DOI Listing
September 1998
4 Reads
2 Citations
2.700 Impact Factor

Action sequencing is impaired in D1A-deficient mutant mice.

Eur J Neurosci 1998 Jul;10(7):2426-32

Institute of Physiology, University of Fribourg, Switzerland.

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July 1998
4 Reads
13 Citations
3.181 Impact Factor

Pemoline alters dopamine modulation of synaptic responses of neostriatal neurons in vitro.

Dev Neurosci 1997 ;19(6):497-504

Mental Retardation Research Center, University of California at Los Angeles, 90024-1759, USA.

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http://dx.doi.org/10.1159/000111247DOI Listing
March 1998
7 Reads
1 Citation
2.700 Impact Factor

Haloperidol decreases hyperkinetic paw treading induced by globus pallidus lesions in the rat.

Exp Neurol 1997 May;145(1):288-94

Department of Psychology, The University of Michigan, Ann Arbor 48109, USA.

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http://dx.doi.org/10.1006/exnr.1997.6472DOI Listing
May 1997
2 Reads
4.700 Impact Factor

Neocortical damage alters synaptic responses of neostriatal neurons in vitro.

Neuroscience 1996 Nov;75(2):361-72

Mental Retardation Research Center, University of California at Los Angeles 90024, USA.

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November 1996
2 Reads
1 Citation
3.360 Impact Factor

Modulatory actions of dopamine on NMDA receptor-mediated responses are reduced in D1A-deficient mutant mice.

J Neurosci 1996 Sep;16(18):5870-82

Mental Retardation Research Center, University of California, Los Angeles 90024-1759, USA.

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September 1996
4 Reads
30 Citations
6.344 Impact Factor

Implementation of action sequences by a neostriatal site: a lesion mapping study of grooming syntax.

J Neurosci 1996 May;16(10):3444-58

Department of Psychology, University of Michigan, Ann Arbor 48109-1109, USA.

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May 1996
8 Reads
38 Citations
6.344 Impact Factor

Pemoline produces ipsilateral turning behavior in unilateral 6-OHDA-lesioned rats.

Prog Neuropsychopharmacol Biol Psychiatry 1996 Apr;20(3):503-14

Department of Psychiatry and Biobehavioral Sciences, UCLA Neuropsychiatric Institute, USA.

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April 1996
6 Reads
3.690 Impact Factor

Decortication decreases paired-pulse facilitation in the neostriatal slice of the rat.

Neurosci Lett 1995 Jun;192(3):213-7

Mental Retardation Research Center, University of California, Los Angeles School of Medicine 90024-1759, USA.

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June 1995
9 Reads
2 Citations
2.060 Impact Factor

Mapping of globus pallidus and ventral pallidum lesions that produce hyperkinetic treading.

Brain Res 1994 Dec;668(1-2):16-29

Department of Psychology, University of Michigan, Ann Arbor 48104, USA.

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December 1994
11 Reads
1 Citation
2.843 Impact Factor

Where does damage lead to enhanced food aversion: the ventral pallidum/substantia innominata or lateral hypothalamus?

Brain Res 1993 Oct;624(1-2):1-10

Department of Psychology, University of Michigan, Ann Arbor 48104-1687.

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October 1993
12 Reads
47 Citations
2.843 Impact Factor

Motivational-sensorimotor interaction controls aphagia and exaggerated treading after striatopallidal lesions.

Behav Neurosci 1990 Oct;104(5):778-95

Department of Psychology, University of Michigan, Ann Arbor 48109.

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October 1990
8 Reads
5 Citations
2.730 Impact Factor

Top co-authors

Wolfram Schultz
Wolfram Schultz

University of Cambridge

3
C Cepeda
C Cepeda

University of California

3
Ryan P Mears
Ryan P Mears

Harvard Medical School

2
Nash N Boutros
Nash N Boutros

Wayne State University

2
W Schultz
W Schultz

Georg-August-University

2
Joshua M Ricker
Joshua M Ricker

J.P. Scott Center for Neuroscience

2