Publications by authors named "Howard A Fine"

100Publications

Generating Patient-Derived Gliomas within Cerebral Organoids.

STAR Protoc 2020 Jun 3;1(1). Epub 2020 Jun 3.

Meyer Cancer Center, Division of Neuro-Oncology, Department of Neurology, New York-Presbyterian Hospital/Weill Cornell Medicine, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.xpro.2019.100008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580125PMC
June 2020

Incorporating genomic signatures into surgical and medical decision-making for elderly glioblastoma patients.

Neurosurg Focus 2020 10;49(4):E11

4Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.3171/2020.7.FOCUS20418DOI Listing
October 2020

The Prognostic Value of MRI Subventricular Zone Involvement and Tumor Genetics in Lower Grade Gliomas.

J Neuroimaging 2020 Jul 28. Epub 2020 Jul 28.

Department of Radiology, Division of Neuroradiology, Weill Cornell Medicine, NewYork-Presbyterian Hospital, New York, NY.

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http://dx.doi.org/10.1111/jon.12763DOI Listing
July 2020

Malignant Gliomas: Simplifying the Complexity.

Authors:
Howard A Fine

Cancer Discov 2019 12;9(12):1650-1652

Weill Cornell Medicine, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-19-1081DOI Listing
December 2019

Integrated PET-MRI for Glioma Surveillance: Perfusion-Metabolism Discordance Rate and Association With Molecular Profiling.

AJR Am J Roentgenol 2019 04 19;212(4):883-891. Epub 2019 Feb 19.

2 Department of Radiology, Division of Neuroradiology, New York-Presbyterian Hospital, Weill Cornell Medicine, 525 E 68th St, Starr Pavilion, Box 141, New York, NY 10065.

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http://dx.doi.org/10.2214/AJR.18.20531DOI Listing
April 2019

MRI Features Associated with TERT Promoter Mutation Status in Glioblastoma.

J Neuroimaging 2019 05 15;29(3):357-363. Epub 2019 Jan 15.

Department of Radiology, New York Presbyterian Hospital-Cornell, New York, NY.

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http://dx.doi.org/10.1111/jon.12596DOI Listing
May 2019

A Phase II trial of tandutinib (MLN 518) in combination with bevacizumab for patients with recurrent glioblastoma.

CNS Oncol 2016 10;5(2):59-67. Epub 2016 Feb 10.

Division of Neuro-Oncology, Director of the Brain Tumor Center, New York-Presbyterian Hospital/Weill Cornell Medical Center, 1305 York Avenue, 9th Floor, New York, NY 10021, USA.

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http://dx.doi.org/10.2217/cns-2015-0010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514626PMC
October 2016

A phase II trial of enzastaurin (LY317615) in combination with bevacizumab in adults with recurrent malignant gliomas.

J Neurooncol 2016 Mar 7;127(1):127-35. Epub 2015 Dec 7.

Division of Neuro-Oncology, Director of the Brain Tumor Center, New York-Presbyterian Hospital/Weill Cornell Medical Center, 1305 York Avenue, 9th Floor, New York, NY, 10021, USA.

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http://dx.doi.org/10.1007/s11060-015-2020-xDOI Listing
March 2016

A phase II trial of tamoxifen and bortezomib in patients with recurrent malignant gliomas.

J Neurooncol 2015 Oct 19;125(1):191-5. Epub 2015 Aug 19.

Division of Neuro-Oncology, Director of the Brain Tumor Center, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1007/s11060-015-1894-yDOI Listing
October 2015

A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma.

Int J Radiat Oncol Biol Phys 2015 Aug 30;92(5):986-992. Epub 2015 Apr 30.

Radiation Oncology Branch, National Cancer Institute/National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2015.04.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510472PMC
August 2015

New strategies in glioblastoma: exploiting the new biology.

Authors:
Howard A Fine

Clin Cancer Res 2015 May 10;21(9):1984-8. Epub 2015 Feb 10.

Division of Hematology and Oncology, The New York University (NYU) Langone Medical Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1328DOI Listing
May 2015

Clinical cancer advances 2015: Annual report on progress against cancer from the American Society of Clinical Oncology.

J Clin Oncol 2015 Mar 20;33(7):786-809. Epub 2015 Jan 20.

Gregory Masters, Helen F. Graham Cancer Center, Newark, DE; Lada Krilov and Richard L. Schilsky, American Society of Clinical Oncology, Alexandria, VA; Howard H. Bailey, University of Wisconsin Hospital and Clinics, Madison, WI; Marcia S. Brose, University of Pennsylvania Abramson Cancer Center, Philadelphia, PA; Harold Burstein and Lisa R. Diller, Dana-Farber Cancer Institute; Don S. Dizon, Massachusetts General Hospital, Boston, MA; Howard A. Fine, New York University Langone Medical Center; Gary K. Schwartz, Columbia University Medical Center, New York, NY; Gregory P. Kalemkerian, University of Michigan Health System; Sandra L. Wong, University of Michigan, Ann Arbor, MI; Mark Moasser, University of California San Francisco School of Medicine; Charles J. Ryan and Alan P. Venook, University of California San Francisco, San Francisco; Steven J. O'Day, Beverly Hills Health Center, Beverly Hills, CA; Michael N. Neuss, Vanderbilt-Ingram Cancer Center, Nashville, TN; Olatoyosi Odenike, University of Chicago; and Jyoti D. Patel, Northwestern University, Chicago, IL.

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http://jco.ascopubs.org/content/early/2015/01/16/JCO.2014.59
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.59.9746
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http://dx.doi.org/10.1200/JCO.2014.59.9746DOI Listing
March 2015

Correction to "master regulators, regulatory networks, and pathways of glioblastoma subtypes".

Cancer Inform 2014 30;13(Suppl 3):91. Epub 2014 Nov 30.

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA. ; New York University Cancer Institute, New York University Langone Medical Center, New York, USA.

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http://dx.doi.org/10.4137/CIN.S22020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251187PMC
March 2015

Master regulators, regulatory networks, and pathways of glioblastoma subtypes.

Cancer Inform 2014 15;13(Suppl 3):33-44. Epub 2014 Oct 15.

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA. ; New York University Cancer Institute, New York University Langone Medical Center, New York, New York, USA.

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http://dx.doi.org/10.4137/CIN.S14027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214595PMC
November 2014

Identification of molecular pathways facilitating glioma cell invasion in situ.

PLoS One 2014 3;9(11):e111783. Epub 2014 Nov 3.

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111783PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218815PMC
February 2016

Timing (and biology) are everything.

Authors:
Howard A Fine

Neuro Oncol 2014 Nov 14;16(11):1431-2. Epub 2014 Oct 14.

The New York University (NYU) Langone Medical Center, Division of Hematology and Oncology, 522 First Avenue, Smilow 1101, New York, NY 10016.

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http://dx.doi.org/10.1093/neuonc/nou285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201078PMC
November 2014

Report of the Jumpstarting Brain Tumor Drug Development Coalition and FDA clinical trials neuroimaging endpoint workshop (January 30, 2014, Bethesda MD).

Neuro Oncol 2014 Oct;16 Suppl 7:vii36-47

Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (P.Y.W., D.A.R.); University of California, Los Angeles School of Medicine, Los Angeles, California (T.F.C., B.M.E., W.B.P.); New York University Langone Medical Center, New York, New York (H.A.F.); Hoffmann-La Roche, Basel, Switzerland (L.A.); Department of Biostatistics, Mayo Clinic Rochester, Rochester, Minnesota (K.B.); Department of Neuro-radiology, University of Heidelberg, Heidelberg, Germany (M.B.); Department of Medical Oncology, Mayo Clinic Rochester, Rochester, Minnesota (J.B.); Brain Tumor Center, University of California, San Francisco, California (S.M.C., M.D.P.); Siemens Healthcare North America, Malvern, Pennsylvania (A.G.S.); Department of Neuro-Oncology, Erasmus M.C.-Daniel den Hoed Cancer Center, Rotterdam, Netherlands (M.v.d.B.); Department of Neuro-Oncology, M.D. Anderson Cancer Center, Houston, Texas (W-K.A.Y.).

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/nou226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195530PMC
October 2014

Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date.

Cancer 2015 Feb 23;121(4):502-16. Epub 2014 Sep 23.

Laura & Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, New York.

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http://dx.doi.org/10.1002/cncr.28968DOI Listing
February 2015

Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells.

J Immunother Cancer 2014 19;2:25. Epub 2014 Aug 19.

Surgery Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, Building 10 Hatfield CRC, Rm 3-5930, 20892-1201 Bethesda, MD, USA ; Current address: Bluebird bio, 150 Second St, Cambridge, MA 02141, USA.

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http://dx.doi.org/10.1186/2051-1426-2-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155770PMC
September 2014

Bevacizumab-related toxicities in the National Cancer Institute malignant glioma trial cohort.

J Neurooncol 2014 Nov 7;120(2):431-40. Epub 2014 Aug 7.

Division of Neuro-Oncology, Neurologic Institute of New York, Columbia University College of Physicians and Surgeons, 710 West 168th Street, NI 9-017, New York, NY, 10032, USA,

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http://dx.doi.org/10.1007/s11060-014-1571-6DOI Listing
November 2014

How to get from here to there: tracking down invasive glioma cells.

Authors:
Howard A Fine

J Natl Cancer Inst 2014 Jun 16;106(6):dju120. Epub 2014 May 16.

Affiliation of author: New York University School of Medicine, Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY.

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http://dx.doi.org/10.1093/jnci/dju120DOI Listing
June 2014

Bevacizumab in glioblastoma--still much to learn.

Authors:
Howard A Fine

N Engl J Med 2014 Feb;370(8):764-5

From the New York University (NYU) Cancer Institute, NYU Langone Medical Center, New York.

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http://dx.doi.org/10.1056/NEJMe1313309DOI Listing
February 2014

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.

Cell Rep 2014 Jan 16;6(2):313-24. Epub 2014 Jan 16.

Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.12.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041390PMC
January 2014

A novel uHPLC-MS/MS method for the quantitation of AZD7451 (AZ12607092) in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2013 Dec 22;942-943:107-12. Epub 2013 Oct 22.

Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, Bethesda, MD, United States.

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http://dx.doi.org/10.1016/j.jchromb.2013.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864870PMC
December 2013

Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels.

PLoS One 2013 29;8(4):e62982. Epub 2013 Apr 29.

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062982PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639162PMC
December 2013

Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization.

PLoS One 2012 7;7(12):e51407. Epub 2012 Dec 7.

Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051407PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517524PMC
June 2013

A phase I/II trial of vandetanib for patients with recurrent malignant glioma.

Neuro Oncol 2012 Dec 25;14(12):1519-26. Epub 2012 Oct 25.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1093/neuonc/nos265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499018PMC
December 2012

Continuous daily sunitinib for recurrent glioblastoma.

J Neurooncol 2013 Jan 20;111(1):41-8. Epub 2012 Oct 20.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, 9030 Old Georgetown Road, #225, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s11060-012-0988-zDOI Listing
January 2013

A phase II study of conventional radiation therapy and thalidomide for supratentorial, newly-diagnosed glioblastoma (RTOG 9806).

J Neurooncol 2013 Jan 20;111(1):33-9. Epub 2012 Oct 20.

Dana-Farber/Brigham and Women's Cancer Center, 75 Francis Street, ASB1-L2, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s11060-012-0987-0DOI Listing
January 2013

Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc.

Cancer Res 2012 Nov 17;72(22):6065-75. Epub 2012 Sep 17.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-2594DOI Listing
November 2012

SnapShot: glioblastoma multiforme.

Cancer Cell 2012 May;21(5):710-710.e1

Center for Cancer Research, National Cancer Institute, National Institutes for Neurological Disorder and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.04.031DOI Listing
May 2012

Refining endpoints in brain tumor clinical trials.

J Neurooncol 2012 Jun 27;108(2):227-30. Epub 2012 Mar 27.

Department of Neuro-Oncology, M.D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/s11060-012-0813-8DOI Listing
June 2012

Many tumors in one: a daunting therapeutic prospect.

Cancer Cell 2011 Dec;20(6):695-7

Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.11.018DOI Listing
December 2011

Spinal cord glioneuronal tumor with neuropil-like islands with 1p/19q deletion in an adult with low-grade cerebral oligodendroglioma.

J Neurooncol 2012 Apr 15;107(2):421-6. Epub 2011 Nov 15.

Neuro-Oncology Branch, National Institutes of Health, 9030 Old Georgetown Rd., Room 221, Bethesda, MD 20892-8202, USA.

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http://dx.doi.org/10.1007/s11060-011-0760-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446125PMC
April 2012

Qualitative network modeling of the Myc-p53 control system of cell proliferation and differentiation.

Biophys J 2011 Nov 1;101(9):2082-91. Epub 2011 Nov 1.

Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.bpj.2011.09.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207173PMC
November 2011

A phase II trial of single-agent bevacizumab in patients with recurrent anaplastic glioma.

Neuro Oncol 2011 Oct 24;13(10):1143-50. Epub 2011 Aug 24.

The Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/neuonc/nor091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177658PMC
October 2011

Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion.

J Natl Cancer Inst 2011 Aug 19;103(15):1162-78. Epub 2011 Jul 19.

Neuro-Oncology Branch, National Cancer Institute/National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1002, USA.

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http://dx.doi.org/10.1093/jnci/djr224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149042PMC
August 2011

Integration and analysis of genome-scale data from gliomas.

Nat Rev Neurol 2011 Jul 5;7(8):439-50. Epub 2011 Jul 5.

The Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disease and Stroke, National Institutes of Health, The Bloch Building, 9030 Old Georgetown Road, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1038/nrneurol.2011.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980233PMC
July 2011

Ischemic stroke and intracranial hemorrhage in glioma patients on antiangiogenic therapy.

J Neurooncol 2011 Nov 27;105(2):281-9. Epub 2011 Apr 27.

Neuro-Oncology Branch, National Cancer Institute and National Institute of Neurological Disorders and Stroke, National Institutes of Health, 9030 Old Georgetown Rd., Bethesda, MD 20892-8202, USA.

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http://dx.doi.org/10.1007/s11060-011-0579-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168718PMC
November 2011

Cancer stem cells in gliomas: identifying and understanding the apex cell in cancer's hierarchy.

Glia 2011 Aug 5;59(8):1148-54. Epub 2011 May 5.

Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Ohio, USA.

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http://dx.doi.org/10.1002/glia.21185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107874PMC
August 2011

A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03.

Neuro Oncol 2011 May 3;13(5):509-16. Epub 2011 Mar 3.

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorder and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/neuonc/nor017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093337PMC
May 2011

Prediction of Associations between microRNAs and Gene Expression in Glioma Biology.

PLoS One 2011 Feb 16;6(2):e14681. Epub 2011 Feb 16.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorder and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014681PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040173PMC
February 2011

Selected human leukocyte antigen class II polymorphisms and risk of adult glioma.

J Neuroimmunol 2011 Apr 30;233(1-2):185-91. Epub 2010 Dec 30.

Yale School of Public Health, Yale School of Medicine, 60 College Street, P.O. Box 208034, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2010.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074044PMC
April 2011

The Ids have it.

Cancer Cell 2010 Dec;18(6):543-5

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ccr.2010.11.028DOI Listing
December 2010

Predicting in vitro drug sensitivity using Random Forests.

Bioinformatics 2011 Jan 5;27(2):220-4. Epub 2010 Dec 5.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/bioinformatics/btq628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018816PMC
January 2011

Malignant gliomas: new translational therapies.

Mt Sinai J Med 2010 Nov-Dec;77(6):655-66

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorders and Stroke/National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/msj.20223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889810PMC
June 2011

Gene pathways and subnetworks distinguish between major glioma subtypes and elucidate potential underlying biology.

J Biomed Inform 2010 Dec 7;43(6):945-52. Epub 2010 Sep 7.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorder and Stroke, National Institutes of Health, Bethesda, MD 20894, USA.

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http://dx.doi.org/10.1016/j.jbi.2010.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241867PMC
December 2010

Scale to predict survival after surgery for recurrent glioblastoma multiforme.

J Clin Oncol 2010 Aug 19;28(24):3838-43. Epub 2010 Jul 19.

Surgical and Molecular Neurooncology Unit, National Institute of Neurological Disorders and Stroke,Neuro-oncology Branch, National Cancer Institute and National Institute of Arthritis and Musculoskeletal andSkin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1200/JCO.2010.30.0582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940401PMC
August 2010

GliomaPredict: a clinically useful tool for assigning glioma patients to specific molecular subtypes.

BMC Med Inform Decis Mak 2010 Jul 15;10:38. Epub 2010 Jul 15.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorder and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1186/1472-6947-10-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912783PMC
July 2010

FastMEDUSA: a parallelized tool to infer gene regulatory networks.

Bioinformatics 2010 Jul 30;26(14):1792-3. Epub 2010 May 30.

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Diseases and Stroke, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/bioinformatics/btq275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894517PMC
July 2010

Risk of meningioma and common variation in genes related to innate immunity.

Cancer Epidemiol Biomarkers Prev 2010 May 20;19(5):1356-61. Epub 2010 Apr 20.

Division of Cancer Epidemiology and Genetics, Neuro-oncology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS Room 7058, Bethesda, MD 20892-7238, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-1151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169167PMC
May 2010

CNAReporter: a GenePattern pipeline for the generation of clinical reports of genomic alterations.

BMC Med Genomics 2010 Apr 9;3:11. Epub 2010 Apr 9.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorder and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1186/1755-8794-3-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872651PMC
April 2010

Bevacizumab for malignant gliomas.

Arch Neurol 2010 Mar;67(3):285-8

Neuro-Oncology Branch, National Cancer Institute, National Institute for Neurological Disorders and Stroke, National Institutes of Health, 9030 Old Georgetown Rd, Bloch Bldg 82, Room 225, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1001/archneurol.2010.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243880PMC
March 2010

A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas.

Neuro Oncol 2010 Feb 22;12(2):181-9. Epub 2010 Jan 22.

Neuro-Oncology Branch, National Cancer Institute, NIH, 9030 Old Georgetown Road, Bloch Bldg. 82, room 225, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/neuonc/nop042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940576PMC
February 2010

DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.

Neuro Oncol 2010 Jan 10;12(1):37-48. Epub 2009 Dec 10.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892-7238, USA.

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/nop012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940551PMC
January 2010

Phase 2 trial of talampanel, a glutamate receptor inhibitor, for adults with recurrent malignant gliomas.

Cancer 2010 Apr;116(7):1776-82

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/cncr.24957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846997PMC
April 2010

Cutaneous pigmentation after photosensitivity induced by vandetanib therapy.

Arch Dermatol 2009 Aug;145(8):923-5

Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bldg 10, Room 12N238, 10 Center Dr, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1001/archdermatol.2009.177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521518PMC
August 2009

Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial.

J Clin Oncol 2009 Sep 27;27(25):4155-61. Epub 2009 Jul 27.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1550 Orleans St, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1200/JCO.2008.21.6895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734427PMC
September 2009

Corneal verticillata after dual anti-epidermal growth factor receptor and anti-vascular endothelial growth factor receptor 2 therapy (vandetanib) for anaplastic astrocytoma.

Cornea 2009 Jul;28(6):699-702

National Eye Institute and daggerNational Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1097/ICO.0b013e3181922146DOI Listing
July 2009

Glioma stem cells: better flat than round.

Cell Stem Cell 2009 Jun;4(6):466-7

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S193459090900222
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http://dx.doi.org/10.1016/j.stem.2009.05.013DOI Listing
June 2009

SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma.

Cell Stem Cell 2009 May;4(5):440-52

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.stem.2009.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227614PMC
May 2009

A phase I trial of enzastaurin in patients with recurrent gliomas.

Clin Cancer Res 2009 May 5;15(10):3617-23. Epub 2009 May 5.

Neuro-Oncology Branch and Biometric Research Branch, National Cancer Institute, National Institute of Neurological Disorder and Stroke, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-3071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227612PMC
May 2009

Glioma stem cells: not all created equal.

Authors:
Howard A Fine

Cancer Cell 2009 Apr;15(4):247-9

Center for Cancer Research, Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ccr.2009.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852885PMC
April 2009

Unsupervised analysis of transcriptomic profiles reveals six glioma subtypes.

Cancer Res 2009 Mar 24;69(5):2091-9. Epub 2009 Feb 24.

Neuro-Oncology Branch and Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845963PMC
March 2009

Rembrandt: helping personalized medicine become a reality through integrative translational research.

Mol Cancer Res 2009 Feb 10;7(2):157-67. Epub 2009 Feb 10.

Center for Biomedical Informatics and Information Technology, Neuro-Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-08
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http://dx.doi.org/10.1158/1541-7786.MCR-08-0435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645472PMC
February 2009

Oxidative response gene polymorphisms and risk of adult brain tumors.

Neuro Oncol 2008 Oct 5;10(5):709-15. Epub 2008 Aug 5.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892-7238, USA.

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http://dx.doi.org/10.1215/15228517-2008-037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666247PMC
October 2008

Invasion suppressor cystatin E/M (CST6): high-level cell type-specific expression in normal brain and epigenetic silencing in gliomas.

Lab Invest 2008 Sep 7;88(9):910-25. Epub 2008 Jul 7.

Department of Pathology, UF-Shands Cancer Center Program in Cancer Genetics, Epigenetics, and Tumor Virology, University of Florida College of Medicine, Gainesville, FL, USA.

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http://dx.doi.org/10.1038/labinvest.2008.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574902PMC
September 2008

Genetic variation in insulin-like growth factors and brain tumor risk.

Neuro Oncol 2008 Aug 18;10(4):553-9. Epub 2008 Jun 18.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7238, USA.

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http://dx.doi.org/10.1215/15228517-2008-026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666228PMC
August 2008

Notch-1 regulates transcription of the epidermal growth factor receptor through p53.

Carcinogenesis 2008 May 20;29(5):918-25. Epub 2008 Mar 20.

Department of Neurology, Division of Neuro-Oncology, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1093/carcin/bgn079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902388PMC
May 2008

Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas.

Mol Cancer Res 2008 Jan 9;6(1):21-30. Epub 2008 Jan 9.

Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorder and Stroke, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-07-0280DOI Listing
January 2008

A phase I trial of lenalidomide in patients with recurrent primary central nervous system tumors.

Clin Cancer Res 2007 Dec;13(23):7101-6

Neuro-Oncology Branch and Medical Oncology Branch, National Cancer Institute, The National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-1546DOI Listing
December 2007

Promising new therapies for malignant gliomas.

Authors:
Howard A Fine

Cancer J 2007 Nov-Dec;13(6):349-54

Neuro-Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 90892, USA.

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http://dx.doi.org/10.1097/PPO.0b013e31815b18dbDOI Listing
February 2008