Publications by authors named "Hossein Dialameh"

6 Publications

  • Page 1 of 1

Living versus deceased kidney transplantation: Comparison of complications.

Urologia 2021 Feb 18:391560321993540. Epub 2021 Feb 18.

Department of Urology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Introduction: It is assumed that the outcome of kidney transplantation from living donors is more favorable than deceased donors. However, over the years there has been an overall improvement in transplant survival from both living and deceased donors. In this article we have evaluated and compared the most recent results in living and deceased donor kidney transplantations.

Patients And Methods: Four hundred and forty six patients underwent kidney transplantation in our center from September 2009 to March 2014. The patients divided in two groups living (group A) and deceased (group B) donor transplantation groups. The patients were followed until September 2016. Acute rejection, graft survival, delayed graft function, renal artery thrombosis, graft nephrectomy, ureterocutaneous fistula, postoperative hypertension, mortality, hospital stay, hyperlipidemia, post transplantation diabetes and lymphocele rate measured and compared in two groups.

Results: Most variables were not different between the two groups except lymphocele and delayed graft function. Lymphocele was more prevalent in group A (13.8% vs 3.1%, -value = 0.02) and delayed graft function results were more desirable in living donor transplantation group (group B).

Conclusion: Although, delayed graft function was less common in transplantation from living donors, short, and long term graft survival was not significantly different in this study.
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http://dx.doi.org/10.1177/0391560321993540DOI Listing
February 2021

The effect of vitamin D supplementation on the progression of benign prostatic hyperplasia: A randomized controlled trial.

Clin Nutr 2020 Nov 7. Epub 2020 Nov 7.

Department of Urology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Background And Aims: Inflammation and proliferation are the cause of benign prostatic hyperplasia (BPH) and are the key components of its mechanism of action. In this study we sought to determine the role of 25-hydroxyvitamin D in BPH, because of its anti-inflammatory activities, and its effect on prostate volume and BPH symptoms.

Methods: This randomized clinical trial (RCT) was conducted on 108 participants >50 years of age who had either asymptomatic or mild BPH symptoms according to the International Prostate Symptom Score (IPSS) questionnaire. Patients were randomly divided into two groups, intervention and control. The intervention group received 50 000 units of vitamin D3 and the control group received a placebo every two weeks for six months. Prostate ultrasound, routine clinical examinations, toucher rectal (TR), and laboratory tests were performed for all patients. After six months, the patients underwent another ultrasound evaluation, measurement of prostate-specific antigen (PSA) levels and completed the IPSS. Results of the evaluations before and after the intervention were compared between the groups using the chi-square, t-test, and logistic regression analysis. Repeated measure analysis was used to evaluate the effect of vitamin D intervention on the changes in the IPSS score.

Results: The mean age of the participants was 56 ± 9 years. In the control group, the mean prostate volume was higher compared to the intervention group (p < 0.001). The control group had a higher mean PSA level than the intervention group (p < 0.001). Although the IPSS score decreased over time in both groups, analysis of variance showed that the amount of change or decrease in IPSS score in the intervention group was significantly more than the control group (p < 0.001).

Conclusions: The results of our study support the effect of vitamin D in reducing prostate volume and PSA levels, and in improving BPH symptoms. Further studies are needed to confirm these findings to verify the use of vitamin D as a treatment for BPH.
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http://dx.doi.org/10.1016/j.clnu.2020.11.005DOI Listing
November 2020

Comparison of sexual function changes in recipients of kidney transplant in females receiving kidney from the living donor and deceased donor.

Urologia 2020 Nov 5;87(4):203-208. Epub 2020 May 5.

Department of Urology, School of Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background And Aim: Chronic renal failure can result in different sexual and reproductive problems for women. Due to lack of information about sexual dysfunction of women with transplanted kidney and superiority of either living or deceased donor, we designed this retrospective cohort study to compare sexual function changes in recipients of kidney transplant in two groups receiving kidney from the living donor and deceased donor using Female Sexual Function Index score.

Methods And Materials: We included 55 female patients who underwent kidney transplant from 22 May 2015 to 22 May 2016 in Sina Hospital (Tehran, Iran). Laboratory factors, including creatinine, blood urea nitrogen, hemoglobin, fasting blood glucose, triglyceride, cholesterol, low-density lipoprotein, and high-density lipoprotein, were evaluated before and after the transplantation. Female Sexual Function Index questionnaire was used to evaluate sexual function of the patients before the transplant, 3 months after the transplant, and 9 months after the transplant.

Results: Our results revealed that there is significant improvement in the Female Sexual Function Index score of the patients after the transplant (p-value < .001). However, we found no significant difference between the scores of the patients with living donor and deceased donor (p-value > .05). Patients' age, creatinine level, low-density lipoprotein, and diastolic blood pressure are negative predictors of Female Sexual Function Index scores.
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http://dx.doi.org/10.1177/0391560320913402DOI Listing
November 2020

Comparing the length of penile mucosa in men with and without premature ejaculation.

Urologia 2016 Jan-Mar;83(1):36-9. Epub 2015 Oct 30.

Urology and Nephrology Research Center, Department of Urology and Renal Transplantation, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran - Iran.

Background: Premature ejaculation is one of the prevalent disorders in men; almost one out of three men between 18 and 59 years old have this disorder with its leading sequel such as lack of self-confidence, anxiety, depression and unsatisfactory intercourse in men and their partners. This study aimed to compare the length of penile mucosa in men with and without premature ejaculation.

Method: Three hundred and eighty patients referring to our hospital from March 2009 to March 2010 were enrolled in the study. First group comprised 190 men with premature ejaculation and second group included 190 men without premature ejaculation as control group that were chosen randomly. A questionnaire was designed to collect data and was completed for both groups. Height, weight, body mass index (BMI), length of penile mucosa, length of penis and intravaginal ejaculation latency time (IELT) were measured.

Results: The mean IELT in premature ejaculation group and control group were 47.58 ± 29.55 and 410.38 ± 190.2 s, respectively (p = 0.001). The mean penis length in premature ejaculation group and control group were 127.25 ± 16.23 and 127.03 ± 17.42 mm, respectively (p = 0.901, with nonsignificant difference); the mean penile mucosa in premature ejaculation group was 33.83 ± 11.54 mm and in control group was 31.40 ± 11.97 mm (p = 0.014, with significant difference).

Conclusion: Longer penile mucosa can be one of the factors in causing premature ejaculation.
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http://dx.doi.org/10.5301/uro.5000158DOI Listing
April 2017

Effect of PTEN Gene Mutations and Environmental Risk Factors on the Progression and Prognosis of Bladder Cancer.

Iran J Public Health 2014 Jan;43(1):56-61

3. Dept. of Pathobiology, School of Medicine, Tehran University of Medical Sciences , Tehran, Iran.

Background: Bladder cancer is the most frequent genitourinary malignancy in Iran. Environmental and genetic factors are the two factors linked with bladder cancer expansion. The aim of this study was to investigate the role of PTEN gene and environmental risk factors on the progression and prognosis of bladder cancer.

Methods: We evaluated 55 tumor specimens and 66 bladder mucosa samples of non-cancerous patients between 2011 and 2013. All samples were analyzed for PTEN mutations using PCR and direct DNA sequencing methods. Demographic data collected, were analyzed using SPSS version 19.0 software and a P value of < 0.05 was considered statistically significant.

Results: Of the 55 patients examined, tumor stage was T1, T2 (T2a, T2b) in 34 (61.8%) and 21 (38.2%) and tumor grade was high, low in 34 (61.8%) and 21 (38.2%), respectively. No mutations in the PTEN gene were found in patients with bladder cancer and control. Among the risk factors studied, only the occupation and history of urinary tract stones, were significantly associated with bladder cancer (P value<0.05). However, other risk factors did not show such a relationship.

Conclusion: No mutation was found in PTEN gene of patients with bladder cancer. Therefore, mutations in this gene cannot predict the prognosis and progression of urothelial bladder cancer. On the other hand, significant rela-tionship was found between occupation and urinary stones with bladder cancer. This communication reflects the im-pact of these factors on the risk of bladder cancer.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454031PMC
January 2014

Stereobiochemical aspects of warfarin isomers for inhibition of enzymatic alkylation of menaquinone-0 to menaquinone-4 in chick liver.

Int J Vitam Nutr Res 1978 ;48(2):131-5

The inhibition of enzymatic activity by the isomers of warfarin for alkylation of menaquinone-0 to menaquinone-4 has been studied in chick liver. Injection of (6,7--3H2)-menaquinone-0 into chicks resulted in the biosynthesis of menaquinone-4 within 3 h. Microsomes of control chicks contained 78 per cent of the total menaquinone-4. (S) (-)-Warfarin and (R) (+)-warfarin isomers inhibited the biosynthesis of menaquinone-4 of about 67 and 17 per cent respectively. Fractionation of soluble microsomal proteins lead to the the isolation of a menaquinone-4 binding protein.
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November 1978