Hossam Abdelsamed

Hossam Abdelsamed

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Hossam Abdelsamed

Hossam Abdelsamed

Publications by authors named "Hossam Abdelsamed"

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Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1.

N Engl J Med 2019 04;380(16):1525-1534

From the Departments of Bone Marrow Transplantation and Cellular Therapy (E.M., B.T., W.J., S.G.), Hematology (S.Z., Z.M., J.C., J.D., X.T., B.Y.R., M.J.W., B.P.S.), Therapeutics Production and Quality (T.L., M.M.M.), Immunology (H.A., B.Y.), Pharmaceutical Sciences (S.J.C.), Biostatistics (G.K., C.L.), and Infectious Diseases (G.M.), St. Jude Children's Research Hospital, Memphis, TN; the Allergy and Clinical Immunology Division, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru (J.C.A.B.); the Department of Pediatrics, Allergy-Immunology Division, Children's Hospital Los Angeles, Los Angeles (J.A.C.), and the Department of Pediatrics, Division of Pediatric Allergy-Immunology-Bone Marrow Transplantation, University of California, San Francisco (UCSF) Benioff Children's Hospital, San Francisco (J.R.L.-B., J.M.P., M.J.C.) - both in California; the Department of Pediatrics, Pediatric Allergy and Immunology, University of New Mexico, Albuquerque (E.D.); University of Oklahoma Health Sciences Center, Tulsa (J.T.L.); Departamento de Pediatria da Universidade de Taubaté, Conselho Nacional de Medicina, São Paulo (A.C.M.A.); Copperfield Childcare, Claremont, South Africa (H.W.); and the Genetic Immunotherapy Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (S.S.D.R., H.L.M.).

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http://www.nejm.org/doi/10.1056/NEJMoa1815408
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http://dx.doi.org/10.1056/NEJMoa1815408DOI Listing
April 2019

Epigenetic Maintenance of Acquired Gene Expression Programs during Memory CD8 T Cell Homeostasis.

Front Immunol 2018 18;9. Epub 2018 Jan 18.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, United States.

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http://journal.frontiersin.org/article/10.3389/fimmu.2018.00
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http://dx.doi.org/10.3389/fimmu.2018.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778141PMC
February 2019

Maintenance of PD-1 on brain-resident memory CD8 T cells is antigen independent.

Immunol Cell Biol 2017 11 22;95(10):953-959. Epub 2017 Aug 22.

Department of Microbiology and Immunology, Penn State College of Medicine, Hershey, PA, USA.

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http://dx.doi.org/10.1038/icb.2017.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698165PMC
November 2017

Homeostatic Proliferation of Human CD8 T Cells.

Bio Protoc 2017 Nov;7(22)

Departments of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.21769/BioProtoc.2619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718202PMC
November 2017

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Cell 2017 Jun 22;170(1):142-157.e19. Epub 2017 Jun 22.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568784PMC
June 2017

Generating long-lived CD8(+) T-cell memory: Insights from epigenetic programs.

Eur J Immunol 2016 07;46(7):1548-62

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1002/eji.201545550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035674PMC
July 2016

EDL-360: A Potential Novel Antiglioma Agent.

J Cancer Sci Ther 2014 Sep;6(9):370-377

Departments of Pathology and Laboratory Medicine, University of Tennessee Health Science Center, USA ; The Center for Cancer Research, University of Tennessee Health Science Center, USA.

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http://www.omicsonline.org/open-access/edl-a-potential-novel
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http://www.omicsonline.org/open-access/edl-a-potential-novel
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http://dx.doi.org/10.4172/1948-5956.1000295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285352PMC
September 2014

TLR2 regulates neutrophil recruitment and cytokine production with minor contributions from TLR9 during hypersensitivity pneumonitis.

PLoS One 2013 30;8(8):e73143. Epub 2013 Aug 30.

Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073143PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758260PMC
April 2014

Genetic variation in Chlamydia trachomatis and their hosts: impact on disease severity and tissue tropism.

Future Microbiol 2013 Sep;8(9):1129-1146

Department of Microbiology, Immunology & Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN, USA.

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http://dx.doi.org/10.2217/fmb.13.80DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009991PMC
September 2013

T-bet controls severity of hypersensitivity pneumonitis.

J Inflamm (Lond) 2011 Jun 23;8(1):15. Epub 2011 Jun 23.

University of Tennessee Health Science Center, Dept, of Microbiology, Immunology and Biochemistry, Memphis, TN 38163, USA.

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http://dx.doi.org/10.1186/1476-9255-8-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131238PMC
June 2011

An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis.

PLoS Pathog 2008 Apr 18;4(4):e1000042. Epub 2008 Apr 18.

Mid-South Center for Biodefense and Security, The University of Tennessee Health Science Center, Memphis, Tennessee, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277464PMC
April 2008