Hope Rugo

Hope Rugo

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Hope Rugo

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Phase II study of irinotecan and temozolomide in breast cancer patients with progressing central nervous system disease.

Breast Cancer Res Treat 2019 Sep 6;177(2):401-408. Epub 2019 Jun 6.

Department of Medicine, Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s10549-019-05309-6DOI Listing
September 2019

Phosphoinositide 3-kinase inhibition in the treatment of hormone receptor-positive breast cancer.

Authors:
Hope S Rugo

Clin Adv Hematol Oncol 2019 Sep;17(9):486-489

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California.

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September 2019

Achieving Improved Survival Outcomes in Advanced Breast Cancer.

Authors:
Hope S Rugo

N Engl J Med 2019 07;381(4):371-372

From the University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco.

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http://dx.doi.org/10.1056/NEJMe1906236DOI Listing
July 2019

A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel.

NPJ Breast Cancer 2019 14;5:17. Epub 2019 Jun 14.

1Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA USA.

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http://dx.doi.org/10.1038/s41523-019-0112-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570645PMC
June 2019

The characterization, management, and future considerations for ErbB-family TKI-associated diarrhea.

Breast Cancer Res Treat 2019 May 22;175(1):5-15. Epub 2019 Jan 22.

City of Hope Medical Group, Inc, 1500 E Duarte Rd, Duarte, CA, 91010, USA.

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http://dx.doi.org/10.1007/s10549-018-05102-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491395PMC
May 2019

Alpelisib for -Mutated, Hormone Receptor-Positive Advanced Breast Cancer.

N Engl J Med 2019 05;380(20):1929-1940

From Institut Gustave Roussy, INSERM Unité 981, Université Paris-Sud, Villejuif (F.A.), Institut de Cancérologie de l'Ouest, St. Herblain (M.C.), and Novartis Pharma, Paris (A.-S.L.) - all in France; Hospital Universitario 12 de Octubre, Madrid (E.C.); National Institute of Oncology (G.R.) and Duna Medical Center (Z.P.), Budapest, Hungary; German Breast Group, Neu-Isenburg, and Center for Hematology and Oncology Bethanien, Frankfurt - both in Germany (S.L.); UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco (H.S.R.); Aichi Cancer Center, Nagoya (H.I.), Kanagawa Cancer Center, Yokohama (T.Y.), Saitama Cancer Center, Saitama (K.I.), and National Hospital Organization Hokkaido Cancer Center, Sapporo (M.T.) - all in Japan; Istituto Oncologico Veneto and the Departments of Surgery, Oncology, and Gastroenterology, University of Padua, Padua, Italy (P.C.); Vanderbilt University, Nashville (I.A.M.); Chaim Sheba Medical Center, Tel Hashomer, Israel (B.K.); National Taiwan University Hospital, Taipei (Y.-S.L.); Novartis Pharma, Basel, Switzerland (D.M., C.W.); Novartis Pharmaceuticals, East Hanover, NJ (S.H.); and Massachusetts General Hospital Cancer Center, Boston (D.J.).

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http://www.nejm.org/doi/10.1056/NEJMoa1813904
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http://dx.doi.org/10.1056/NEJMoa1813904DOI Listing
May 2019

Demystifying biosimilars: development, regulation and clinical use.

Future Oncol 2019 Mar 30;15(7):777-790. Epub 2018 Nov 30.

Pfizer, Maidenhead, UK.

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https://www.futuremedicine.com/doi/10.2217/fon-2018-0680
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http://dx.doi.org/10.2217/fon-2018-0680DOI Listing
March 2019

Advance Care Planning in Community: An Evaluation of a Pilot 2-Session, Nurse-Led Workshop.

Am J Hosp Palliat Care 2019 Feb 28;36(2):143-146. Epub 2018 Aug 28.

4 Division of Hematology and Oncology, Department of Medicine, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.

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http://journals.sagepub.com/doi/10.1177/1049909118797612
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http://dx.doi.org/10.1177/1049909118797612DOI Listing
February 2019

Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer.

N Engl J Med 2019 02;380(8):741-751

From the Massachusetts General Hospital Cancer Center (A.B., S.J.I.) and Dana-Farber Cancer Institute (S.M.T.), Harvard Medical School, Boston; Vanderbilt-Ingram Cancer Center, Nashville (I.A.M., V.G.A.); Weill Cornell Medical College (L.T.V.) and New York-Presbyterian-Columbia University Irving Medical Center (K.K.), New York; University of Colorado Cancer Center, Aurora (J.R.D.); Texas Oncology, Baylor University Medical Center, US Oncology, Dallas (J.O.); Orlando Health University of Florida Health Cancer Center, Orlando (R.L.M., N.C.S.); Yale University School of Medicine, New Haven, CT (A.D.S.); University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco (H.S.R.); Immunomedics, Morris Plains, NJ (D.M.G., R.I., S.W., R.M.S., W.A.W.); and AIS Consulting, Ann Arbor, MI (A.M.S.).

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http://www.nejm.org/doi/10.1056/NEJMoa1814213
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http://dx.doi.org/10.1056/NEJMoa1814213DOI Listing
February 2019

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer.

N Engl J Med 2018 11 20;379(22):2108-2121. Epub 2018 Oct 20.

From the Barts Cancer Institute, Queen Mary University of London, London (P.S.); Perlmutter Cancer Center, New York University School of Medicine, New York (S.A.); the Department of Medicine, University of California, San Francisco, San Francisco (H.S.R.), and Genentech, South San Francisco (L.M., S.Y.C., R.F.) - both in California; University Hospital Heidelberg, Heidelberg, Germany (A.S.); Centro de Pesquisa em Oncologia, Hospital São Lucas, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre (C.H.B.), and the University of São Paulo, São Paulo (R.H.) - both in Brazil; Aichi Cancer Center Hospital, Nagoya, Japan (H.I.); the Department of Medical Oncology, Institut Curie, Paris (V.D.); Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea (S.-A.I.); Florida Cancer Specialists and Research Institute, New Port Richey (G.S.W.); Roche, Basel, Switzerland (V.H., A.H.); Dana-Farber Cancer Institute, Boston (E.P.W.); Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia (S.L.); and the Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore (L.A.E.).

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http://www.nejm.org/doi/10.1056/NEJMoa1809615
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http://dx.doi.org/10.1056/NEJMoa1809615DOI Listing
November 2018

The DigniCap Scalp Cooling System and its use in the treatment of chemotherapy-induced alopecia.

Future Oncol 2018 Oct 12;14(24):2461-2469. Epub 2018 Jul 12.

Helen Diller Family Comprehensive Center, University of California, San Francisco, CA 94115, USA.

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https://www.futuremedicine.com/doi/10.2217/fon-2018-0178
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http://dx.doi.org/10.2217/fon-2018-0178DOI Listing
October 2018

Circulating Tumors Cells as a Biomarker of Radiation Benefit.

JAMA Oncol 2018 08 9;4(8):e180194. Epub 2018 Aug 9.

University of California, San Francisco, Comprehensive Cancer Center, San Francisco.

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http://dx.doi.org/10.1001/jamaoncol.2018.0194DOI Listing
August 2018

Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation.

N Engl J Med 2018 08 15;379(8):753-763. Epub 2018 Aug 15.

From the University of Texas M.D. Anderson Cancer Center, Houston (J.K.L.), and the Texas Oncology-Baylor Charles A. Sammons Cancer Center, US Oncology Network, Dallas (J.L.B.) - both in Texas; University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center (H.S.R.), and Pfizer (R.G.W.Q., D.M., I.C.T., A.L.H.), San Francisco, University of California, Los Angeles, Los Angeles (S.A.H.), and Kaiser Permanente, Northern California, Vallejo (L.F.) - all in California; the Department of Obstetrics and Gynecology, Klinikum Rechts der Isar, Technische Universität München (J.E.), and Interdisziplinäres Onkologisches Zentrum München (W.E.) - both in Munich, Germany; Institut Paoli-Calmettes, Marseille (A.G.), and Institut Claudius Regaud, Institut Universitaire du Cancer Toulouse, Toulouse (H.R.) - both in France; Seoul National University Hospital (K.-H.L.) and Samsung Medical Center (Y.-H.I.) - both in Seoul, South Korea; Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel (R.Y.); Banner M.D. Anderson Cancer Center, Gilbert, AZ (L.A.M.); and Instituto de Investigación Sanitaria Gregorio Marañón, Centro de Investigación Biomédica en Red Oncología, Grupo Español de Investigación en Cáncer de Mama, Universidad Complutense, Madrid (M.M.).

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http://dx.doi.org/10.1056/NEJMoa1802905DOI Listing
August 2018

Highlights in breast cancer from the 2018 American Society of Clinical Oncology annual meeting.

Authors:
Hope S Rugo

Clin Adv Hematol Oncol 2018 Aug;16(8):533-537

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California.

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August 2018

Strategies and Progress of Endocrine Therapy for Patients with Metastatic Breast Cancer.

Adv Exp Med Biol 2017 ;1026:403-418

Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University, Cancer Hospital & Institute, Beijing, 100142, China.

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http://dx.doi.org/10.1007/978-981-10-6020-5_19DOI Listing
July 2018

The new world of biosimilars in oncology: Translation of data to the clinic.

Eur J Cancer 2018 06 18;96:125-127. Epub 2018 Apr 18.

Ramon y Cajal University Hospital, Madrid, Spain; Vall D'Hebron Institute of Oncology, Barcelona, Spain; IOB Institute of Oncology, Quiron Group, Madrid & Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ejca.2018.03.005DOI Listing
June 2018

Combined peripheral natural killer cell and circulating tumor cell enumeration enhance prognostic efficiency in patients with metastatic triple-negative breast cancer.

Chin J Cancer Res 2018 Jun;30(3):315-326

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing 100142, China.

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http://dx.doi.org/10.21147/j.issn.1000-9604.2018.03.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037585PMC
June 2018

Phosphatidylinositol 3-Kinase α-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study.

J Clin Oncol 2018 05 5;36(13):1291-1299. Epub 2018 Feb 5.

Dejan Juric, Massachusetts General Hospital Cancer Center, Boston; Alan Huang, Novartis Institutes for BioMedical Research, Cambridge, MA; Jordi Rodon and Josep Tabernero, Vall d'Hebron University Hospital and Institute of Oncology, Universitat Autònoma de Barcelona; Marta Gil-Martin, Catalan Institute of Oncology - Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain; Filip Janku, The University of Texas MD Anderson Cancer Center, Houston, TX; Howard A. Burris, Sarah Cannon Research Institute and Tennessee Oncology; Jordan Berlin, Vanderbilt-Ingram Cancer Center, Nashville, TN; Jan H.M. Schellens, Netherlands Cancer Institute, Amsterdam, the Netherlands; Mark R. Middleton, National Institute for Health Research, Oxford Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom; Martin Schuler, West German Cancer Center, University Duisburg-Essen, and German Cancer Consortium, Partner Site University Hospital Essen, Essen; Ruth Seggewiss-Bernhardt, Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany; Hope S. Rugo, University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; Douglas Bootle, David Demanse, Lars Blumenstein, and Cornelia Quadt, Novartis Pharma AG, Basel, Switzerland; Christina Coughlin, Novartis Pharmaceuticals Corporation, East Hanover, NJ; and José Baselga, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2017.72.7107
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http://dx.doi.org/10.1200/JCO.2017.72.7107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920739PMC
May 2018

Scalp Hypothermia for Preventing Alopecia During Chemotherapy. A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Clin Breast Cancer 2018 02 10;18(1):19-28. Epub 2017 Aug 10.

Medical Device Consultants of Ridgewood LLC, Ridgewood, NJ. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2017.07.012DOI Listing
February 2018

Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy.

Breast Cancer Res Treat 2018 01 18;167(1):117-122. Epub 2017 Sep 18.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 1600 Divisadero St, San Francisco, CA, 94115, USA.

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http://link.springer.com/10.1007/s10549-017-4506-z
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http://dx.doi.org/10.1007/s10549-017-4506-zDOI Listing
January 2018

Emerging data on improving response to hormone therapy: the role of novel targeted agents.

Expert Rev Anticancer Ther 2018 01 8;18(1):3-18. Epub 2017 Dec 8.

b Division of Hematology and Oncology , University of California San Francisco, Helen Diller Family Comprehensive Cancer Center , San Francisco , CA , USA.

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http://dx.doi.org/10.1080/14737140.2018.1412259DOI Listing
January 2018

TIM-3 Regulates CD103 Dendritic Cell Function and Response to Chemotherapy in Breast Cancer.

Cancer Cell 2018 01;33(1):60-74.e6

Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive SRB-2, Tampa, FL 33612, USA; Department of Breast Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764109PMC
January 2018

Safety and Efficacy of Pembrolizumab in Advanced, Programmed Death Ligand 1-Positive Cervical Cancer: Results From the Phase Ib KEYNOTE-028 Trial.

J Clin Oncol 2017 Dec 2;35(36):4035-4041. Epub 2017 Nov 2.

Jean-Sebastien Frenel, Institut de Cancerologie de l'Ouest, Centre René Gauducheau, Saint-Herblain; Christophe Le Tourneau, Institut Curie, Paris and Saint-Cloud, and Institut National de la Santé et de la Recherche Médicale U900 Research Unit, Saint-Cloud; Carlos Gomez-Roca, Institut Claudius Regaud, Toulouse; Andrea Varga, Gustave Roussy, Villejuif, France; Bert O'Neil, Indiana University Health University Hospital, Indianapolis, IN; Patrick A. Ott, Dana-Farber Cancer Institute, Boston, MA; Sarina A. Piha-Paul, The University of Texas MD Anderson Cancer Center, Houston, TX; Emilie M.J. van Brummelen, The Netherlands Cancer Institute, Amsterdam, Netherlands; Hope S. Rugo, University of California, San Francisco, San Francisco, CA; and Shari Thomas, Sanatan Saraf, and Reshma Rangwala, Merck & Co., Inc., Kenilworth, NJ.

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http://dx.doi.org/10.1200/JCO.2017.74.5471DOI Listing
December 2017

Real-world use of scalp cooling to reduce chemotherapy-related hair loss.

Authors:
Hope S Rugo

Clin Adv Hematol Oncol 2017 Nov;15(11):828-831

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California.

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November 2017

Use of Neoadjuvant Platinum-The Ongoing Conundrum.

JAMA Oncol 2017 10;3(10):1312-1314

Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1001/jamaoncol.2017.1954DOI Listing
October 2017

Dual HER2 Blockade.

Breast Care (Basel) 2017 Oct 30;12(5):345-349. Epub 2017 Oct 30.

Gynecology Clinic, HELIOS Hospital Berlin Buch, Berlin, Germany.

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http://dx.doi.org/10.1159/000484226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704717PMC
October 2017

Tyrosine Kinase Inhibitors for Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer: Is Personalizing Therapy Within Reach?

J Clin Oncol 2017 09 7;35(27):3089-3091. Epub 2017 Aug 7.

Amy Jo Chien and Hope S. Rugo, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2017.73.5670DOI Listing
September 2017

Safety and Antitumor Activity of Pembrolizumab in Advanced Programmed Death Ligand 1-Positive Endometrial Cancer: Results From the KEYNOTE-028 Study.

J Clin Oncol 2017 Aug 10;35(22):2535-2541. Epub 2017 May 10.

Patrick A. Ott, Dana-Farber Cancer Institute, Boston, MA; Michael J. Pishvaian, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC; Hope S. Rugo, University of California San Francisco, San Francisco, CA; Igor Puzanov, Roswell Park Cancer Institute, Buffalo, NY; Janice M. Mehnert, Rutgers Cancer Institute of New Jersey, New Brunswick; Marion Carrigan, Sanatan Saraf, and Mei Chen, Merck, Kenilworth, NJ; Yung-Jue Bang, Seoul National University College of Medicine, Seoul, Republic of Korea; Dominique Berton-Rigaud, Institut de Cancérologie de l'Ouest Centre René Gauducheau, Saint-Herblain; Jean-Charles Soria, Gustave Roussy and University Paris-Sud, Villejuif, France; Elena Elez, Vall d'Hebron Institute of Oncology, Barcelona, Spain; Kyaw L. Aung, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; and Juanita Lopez, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2017.72.5952DOI Listing
August 2017

Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.

Breast Cancer Res Treat 2017 Aug 13;165(1):151-159. Epub 2017 May 13.

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA.

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http://link.springer.com/10.1007/s10549-017-4288-3
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http://dx.doi.org/10.1007/s10549-017-4288-3DOI Listing
August 2017

Erratum to: Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.

Breast Cancer Res Treat 2017 08;165(1):161

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s10549-017-4350-1DOI Listing
August 2017

Concerns About Methodology of a Trial Investigating Vaginal Health During Aromatase Inhibitor Therapy for Breast Cancer-Reply.

JAMA Oncol 2017 08;3(8):1142

Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco.

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http://oncology.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoncol.2017.2077DOI Listing
August 2017

Highlights in breast cancer from the 2017 American Society of Clinical Oncology Annual Meeting.

Authors:
Hope S Rugo

Clin Adv Hematol Oncol 2017 Aug;15(8):607-614

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California.

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August 2017

Breast Cancer-Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual.

CA Cancer J Clin 2017 07 14;67(4):290-303. Epub 2017 Mar 14.

Professor; Co-Director, Breast Cancer Research Program, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.3322/caac.21393DOI Listing
July 2017

Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis.

Breast Cancer Res Treat 2017 Jun 8;163(2):199-205. Epub 2017 Mar 8.

Medical Device Consultants Ridgewood, LLC, 99 Glenwood Rd, Ridgewood, NJ, 07450, USA.

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http://dx.doi.org/10.1007/s10549-017-4185-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410200PMC
June 2017

Efficacy of NEPA (netupitant/palonosetron) across multiple cycles of chemotherapy in breast cancer patients: A subanalysis from two phase III trials.

Breast 2017 Jun 10;33:76-82. Epub 2017 Mar 10.

IMO Clinique de Genolier, CH-1272, Genolier, Vaud, Switzerland.

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http://dx.doi.org/10.1016/j.breast.2017.02.017DOI Listing
June 2017

Improving Response to Hormone Therapy in Breast Cancer: New Targets, New Therapeutic Options.

Am Soc Clin Oncol Educ Book 2016 ;35:e40-54

From the UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; University of San Francisco School of Medicine, San Francisco, CA; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO.

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http://dx.doi.org/10.1200/EDBK_159198DOI Listing
January 2017

Targeting the host immune system: PD-1 and PD-L1 antibodies and breast cancer.

Curr Opin Support Palliat Care 2016 12;10(4):336-342

aDepartment of Medical Oncology, Dubai Hospital, UAE bUniversity of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA.

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http://dx.doi.org/10.1097/SPC.0000000000000243DOI Listing
December 2016

NCCN Guidelines Insights: Older Adult Oncology, Version 2.2016.

J Natl Compr Canc Netw 2016 11;14(11):1357-1370

From St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; University of Michigan Comprehensive Cancer Center; Fox Chase Cancer Center; UC San Diego Moores Cancer Center; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; City of Hope Comprehensive Cancer Center; Duke Cancer Institute; University of Colorado Cancer Center; The University of Texas MD Anderson Cancer Center; Moffitt Cancer Center; Fred & Pamela Buffett Cancer Center; Yale Cancer Center/Smilow Cancer Hospital; Mayo Clinic Cancer Center; Dana-Farber/Brigham and Women's Cancer Center; Memorial Sloan Kettering Cancer Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; Stanford Cancer Institute; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; Roswell Park Cancer Institute; UCSF Helen Diller Family Comprehensive Cancer Center; Huntsman Cancer Institute at the University of Utah; Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute; Consultant; Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; and National Comprehensive Cancer Network.

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http://dx.doi.org/10.6004/jnccn.2016.0146DOI Listing
November 2016

When to Treat, With What, and for How Long: That Is the Question!

J Oncol Pract 2016 11;12(11):1160-1162

Dubai Hospital, Dubai, United Arab Emirates and University of California San Francisco Comprehensive Cancer Center, San Francisco, CA.

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http://ascopubs.org/doi/10.1200/JOP.2016.017624
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http://dx.doi.org/10.1200/JOP.2016.017624DOI Listing
November 2016

Palbociclib and Letrozole in Advanced Breast Cancer.

N Engl J Med 2016 11;375(20):1925-1936

From the Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at the University of California, Los Angeles, Santa Monica (R.S.F., D.J.S.), the Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco (H.S.R.), and Pfizer, La Jolla (E.G., D.R.L., S.R.) - all in California; Hospital Gregorio Maranon, Universidad Complutense, Madrid (M.M.); U.S. Oncology Research, The Woodlands, TX (S.J.); Cancer Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea (S.-A.I.); British Columbia Cancer Agency, Vancouver, Canada (K.G.); Brustzentrum der Universität München (LMU), Munich, Germany (N.H.); State Budget Medical Institution Republican Clinical Oncology, Ufa, Russia (O.N.L.); All-Ireland Cooperative Oncology Research Group, Dublin (J.M.W.); M.D. Anderson Cancer Center, University of Texas, Houston (S.M.); and Institut Curie, Paris (V.D.).

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http://dx.doi.org/10.1056/NEJMoa1607303DOI Listing
November 2016

Endocrine Therapy for Hormone Receptor-Positive Metastatic Breast Cancer: American Society of Clinical Oncology Guideline.

J Clin Oncol 2016 09 23;34(25):3069-103. Epub 2016 May 23.

Hope S. Rugo, University of California San Francisco Comprehensive Cancer Center; Barbara Fowble, University of California San Francisco, San Francisco; Rita S. Mehta, University of California Irvine, Orange, CA; R. Bryan Rumble, American Society of Clinical Oncology, Alexandria; James L. Khatcheressian, Virginia Cancer Institute, Richmond, VA; Erin Macrae, Columbus Oncology and Hematology Associates, Columbus, OH; Debra L. Barton, University of Michigan School of Nursing, Ann Arbor, MI; Hannah Klein Connolly, Patient Representative, Edina, MN; Maura N. Dickler, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY; Lesley Fallowfield, Sussex Health Outcomes Research and Education in Cancer, Brighton and Sussex Medical School, University of Sussex, Sussex; Stephen R.D. Johnston, Royal Marsden Hospital, London, United Kingdom; James N. Ingle, Mayo Clinic, Rochester, MN; Mohammad Jahanzeb, University of Miami Sylvester Comprehensive Cancer Center, Deerfield Beach, FL; Larissa A. Korde, University of Washington, Seattle, WA; Hyman B. Muss, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC; and Harold J. Burstein, Dana-Farber Cancer Center, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2016.67.1487DOI Listing
September 2016

Phase III Trial Evaluating Letrozole As First-Line Endocrine Therapy With or Without Bevacizumab for the Treatment of Postmenopausal Women With Hormone Receptor-Positive Advanced-Stage Breast Cancer: CALGB 40503 (Alliance).

J Clin Oncol 2016 08 2;34(22):2602-9. Epub 2016 May 2.

Maura N. Dickler, Mary Ellen Moynahan, Diana E. Lake, and Clifford A. Hudis, Memorial Sloan Kettering Cancer Center, New York, NY; William T. Barry, Dana-Farber Cancer Institute; Eric P. Winer, Dana-Farber/Partners Cancer Care, Boston, MA; Constance T. Cirrincione, Duke University, Durham, NC; Matthew J. Ellis, Baylor College of Medicine; Debasish Tripathy, The University of Texas MD Anderson Cancer Center, Houston, TX; Federico Innocenti and Lisa A. Carey, University of North Carolina at Chapel Hill, Chapel Hill, NC; Arti Hurria, City of Hope, Duarte; Hope S. Rugo, University of California at San Francisco, San Francisco, CA; Olwen Hahn, Alliance for Clinical Trials in Oncology, Chicago, IL; and Bryan P. Schneider, Indiana University School of Medicine, Indianapolis, IN.

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http://dx.doi.org/10.1200/JCO.2015.66.1595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012690PMC
August 2016

Still Refining Adjuvant Endocrine Therapy in Premenopausal Women: Not Too Much, Not Too Little.

J Clin Oncol 2016 07 16;34(19):2203-5. Epub 2016 May 16.

University of California San Francisco Comprehensive Cancer Center, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2016.67.0463DOI Listing
July 2016

Highlights in breast cancer from the 2016 American Society of Clinical Oncology Annual Meeting.

Authors:
Hope S Rugo

Clin Adv Hematol Oncol 2016 Jul;14(7):494-7

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California.

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July 2016

Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer.

N Engl J Med 2016 Jul;375(1):23-34

From University of California, San Francisco (UCSF) (H.S.R., C.Y., L.J.V., M.B.B., N.M.H., A.J.C., C.E., J.L., S.E.D., G.L.H., L.J.E.), and QuantumLeap Healthcare Collaborative (M.P.), San Francisco, Buck Institute for Research and Aging, Novato (C.Y.), University of California, Davis, Davis (M.H.), University of California San Diego, San Diego (A.M.W., R.S.), and University of Southern California, Los Angeles (D.T.) - all in California; University of Chicago (O.I.O., R.N.), and Loyola University (K.S.A.), Chicago; University of Pennsylvania, Philadelphia (A.D.); Gemini Group, Ann Arbor, MI (J.P.); University of Texas M.D. Anderson Cancer Center, Houston (W.F.S., L.P., S.L.M., D.A.B.), UT Southwestern Medical Center, Dallas (D.M.E., B.B.H.), and Berry Consultants, Austin (A.S., D.A.B.) - all in Texas; University of Minnesota, Minneapolis (D.Y.), and Mayo Clinic, Rochester (J.C.B., T.C.H.) - both in Minnesota; Swedish Medical Center, Seattle (H.G.K.); Georgetown Lombardi Comprehensive Cancer Center, Washington, DC (M.C.L., C.I.); University of Kansas, Lawrence (Q.J.K.); University of Arizona, Tucson (J.E.L., R.K.V.), and Mayo Clinic, Scottsdale (D.W.N.) - both in Arizona; Oregon Health and Sciences University, Portland (S.Y.C., K.A.K.); University of Denver, Denver (A.D.E.); Inova Fairfax Hospital, Falls Church, VA (K.K.E.); and Emory University, Atlanta (W.C.W.).

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http://dx.doi.org/10.1056/NEJMoa1513749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259561PMC
July 2016