Publications by authors named "Hooshyar Hossini"

9 Publications

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Water and wastewater as potential sources of SARS-CoV-2 transmission: a systematic review.

Rev Environ Health 2021 Feb 16. Epub 2021 Feb 16.

Department of Environmental Health Engineering, Kermanshah University of Medical Sciences, Kermanshah, Iran.

An important group of viruses are Coronaviruses that affect the health of people worldwide, in particular the acute respiratory syndrome. The present work has addressed the updated literature on the topic of coronaviruses transmission through water and wastewater as well as identified gaps in research to inform future studies. In total, 198 articles were selected, then after screening, 48 eligible studies were fully reviewed. Accordingly, the studies showed that the coronavirus has been isolated and identified from water as well as wastewater. The results of researches show that the presence of SARS-Co-2 virus in municipal wastewater is possible due to the excretion of the virus in human feces. In addition, the SARS-Co-2 virus was isolated from contaminated water and rivers, but there is insufficient evidence for virus transmission by water and wastewater. Water and wastewater treatment methods are able to reduce the pollution load caused by this virus in water sources. Water disinfection has an effective role in removing it from water and wastewater sources. Due to the short period of time in the global pandemic and the small number of studies in this field, further studies are needed to make a definite statement about the transferability of virus in water and wastewater.
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http://dx.doi.org/10.1515/reveh-2020-0148DOI Listing
February 2021

The hybrid system successfully to consisting of activated sludge and biofilter process from hospital wastewater: Ecotoxicological study.

J Environ Manage 2020 Dec 16;276:111098. Epub 2020 Sep 16.

Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.

This article aimed to demonstrate solution hospital wastewater due to more consumption of antibiotics, public concern has been significantly increased for usage, fates and occurrences of these emerging compounds in the environments and biota. Therefore, it does need more discoveries about occurrences and new treatment methods. Since the conventional treatment methods are low efficient on antibiotics, integration and combination of biological systems together or with an additional process has been shown that provided a better result. However, here, the potential of a full scale combined treating system with activated sludge-scoria biofilter (ASSB) was investigated for removal of ceftriaxone (CEF) and amoxicillin (AMX). To determine the potential biodegradability of proposed system, the solid-water distribution coefficient (K) was calculated. Overally, 118 samples were collected from three points; wastewater entering, exiting the activated sludge, and exiting the biofilter. To determine the amount of CEF and AMX antibiotics, the samples were analyzed using HPLC-UV. The results showed that the activated sludge system were able to eliminate the AMX and CEF antibiotics about 70.36 and 84.49%, respectively. In compare to activated sludge, the average mean of ASSB system for the removal efficiency were 87.53% (for AMX) and 93.17% (for CEF), respectively. As a result, it can be found that the efficiency of the combined activated sludge-biofilter system in removing of the low levels of antibiotics was more than individual activated system. The result of K revealed that AMX (with a K about 0.172) has lower tendency to biomass rather than CEF (with a K about 0.512). The ecological toxicity assessment guaranteed there is no risk for fish and daphnia when the activated sludge and also ASSB effluents to be discharged into the environment even without any diluting.
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http://dx.doi.org/10.1016/j.jenvman.2020.111098DOI Listing
December 2020

An updated min-review on environmental route of the SARS-CoV-2 transmission.

Ecotoxicol Environ Saf 2020 Oct 9;202:111015. Epub 2020 Jul 9.

Department of Environmental Health Engineering, School of Public Health, Social Development & Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran. Electronic address:

The risk of newly emerging diseases is constantly present in a world where changes occur significantly in climatic, commercial, and ecological conditions, in addition to the development of biomedical investigations in new situations. An epidemic respiratory disease instigated by a new coronavirus was initially identified in and has resulted in the current global dissemination. This viral strain and its related disease has been termed "SARS-CoV-2" and "coronavirus disease 2019" (abbreviated "COVID-19" or "2019-nCoV"), respectively, which is transmitted simply between individuals. The World Health Organization (WHO) announced the COVID-19 outburst as a pandemic on March 11, which necessitates a cooperative endeavour globally for mitigating the spread of COVID-19. The absence of previous, and minimum present-day information, particularly concerning the path of contagion have precluded the control of this disease. The present article, therefore, describes the SARS-CoV-2 paths of contagion such as drinking water, solid waste, sewer water, ambient air, and the rest of emerging likely paths.
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http://dx.doi.org/10.1016/j.ecoenv.2020.111015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346818PMC
October 2020

Site selection and environmental risks assessment of medical solid waste landfill for the City of Kermanshah-Iran.

Int J Environ Health Res 2020 Mar 17:1-13. Epub 2020 Mar 17.

Department of Geology- Science College, Salahaddin University, Erbil, Kurdistan Region, Iraq.

In this study, an integration of multi-criteria evaluation, geographic information system, and remote sensing techniques were used for site selection of medical waste landfills in Kermanshah, Iran. Also, an environmental risk assessment for the selected site has been conducted in order to minimize the possible hazardous. The GIS and remote sensing were used for acquiring and preparing layers and maps and the multi-criteria evaluation was used for setting aim, criteria selection, criteria weighting, and final decision making. The results showed that only 1.2% of the study area is scored high-suitable, while 90% of the area is considered unsuitable that makes this region critical for preservation. After further assessment and field visits, a suitable site was selected for landfilling. Environmental risk assessment showed that the selected site poses a low-level of risks to the environment and surrounding areas and this is because various environmental and health aspects have been considered in the site selection process.
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http://dx.doi.org/10.1080/09603123.2020.1742876DOI Listing
March 2020

Molecular Mechanism of Aniline Induced Spleen Toxicity and Neuron Toxicity in Experimental Rat Exposure: A Review.

Curr Neuropharmacol 2019 ;17(3):201-213

Research Center for Environmental Determinants of Health (RCEDH), School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Aniline exposure leads to neuron and spleen toxicity specifically and makes diverse neurological effects and sarcoma that is defined by splenomegaly, hyperplasia, and fibrosis and tumors formation at the end. However, the molecular mechanism(s) of aniline-induced spleen toxicity is not understood well, previous studies have represented that aniline exposure results in iron overload and initiation of oxidative/nitrosative disorder stress and oxidative damage to proteins, lipids and DNA subsequently, in the spleen. Elevated expression of cyclins, cyclin-dependent kinases (CDKs) and phosphorylation of pRB protein along with increases in A, B and CDK1 as a cell cycle regulatory proteins cyclins, and reduce in CDK inhibitors (p21 and p27) could be critical in cell cycle regulation, which contributes to tumorigenic response after aniline exposure. Aniline-induced splenic toxicity is correlated to oxidative DNA damage and initiation of DNA glycosylases expression (OGG1, NEIL1/2, NTH1, APE1 and PNK) for removal of oxidative DNA lesions in rat. Oxidative stress causes transcriptional up-regulation of fibrogenic/inflammatory factors (cytokines, IL- 1, IL-6 and TNF-α) via induction of nuclear factor-kappa B, AP-1 and redox-sensitive transcription factors, in aniline treated-rats. The upstream signalling events as phosphorylation of IκB kinases (IKKα and IKKβ) and mitogen-activated protein kinases (MAPKs) could potentially be the causes of activation of NF-κB and AP-1. All of these events could initiate a fibrogenic and/or tumorigenic response in the spleen. The spleen toxicity of aniline is studied more and the different mechanisms are suggested. This review summarizes those events following aniline exposure that induce spleen toxicity and neurotoxicity.
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http://dx.doi.org/10.2174/1570159X16666180803164238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425079PMC
June 2019

Simultaneous wastewater treatment and biogas production using integrated anaerobic baffled reactor granular activated carbon from baker's yeast wastewater.

Environ Technol 2018 Nov 30;39(21):2724-2735. Epub 2017 Aug 30.

c Department of Hydraulics and Sanitation, Engineering School of São Carlos , University of São Paulo (USP) , São Paulo , Brazil.

In this study, simultaneous degradation of organic matter and color removal from food processing industries wastewater using an integrated anaerobic baffled reactor granular activated carbon (IABRGAC) was investigated. Theretofore, effective parameters such as hydraulic retention time (HRT) and granular activated carbon (GAC) filling ratio were studied. The bioreactor was operated at 3, 4 and 5 d of HRT and GAC filling ratio of 20%, 35% and 50%. To analyze and optimize the independent operating variables, response surface methodology was applied. Operating condition was optimized for HRT (4 d) and GAC filling ratio (50%). Better COD (94.6%) and BOD (93.7%) removal efficiency occurred with loading COD of 15,000 mg/L, with diminished wastewater color around 54% and turbidity to 54 NTU. In addition, methane production, methane yielding rate (Y) and specific methanogenic activity (SMA) test in an integrated system were investigated. The system IABRGAC was able to generate a volumetric rate about 0.31 and 0.44 L/g COD d at the experimental condition. The Y was between 0.31 and 0.44 L/g COD.d and SMA was between 0.13 and 0.38 g COD/g volatile suspended solid. Based on results it can be concluded that the IABRGAC to be a successful pretreatment for highstrength wastewater before discharging the final effluent to sewerage and aerobic treating processes.
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http://dx.doi.org/10.1080/09593330.2017.1365939DOI Listing
November 2018

Application of high rate integrated anaerobic-aerobic/biogranular activated carbon sequencing batch reactor (IAnA-BioGACSBR) for treating strong municipal landfill leachate.

Sci Rep 2017 06 8;7(1):3109. Epub 2017 Jun 8.

King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

The aim of the present study is to evaluate the application of high rate integrated anaerobic-aerobic/biogranular activated carbon sequencing batch reactor (IAnA-BioGACSBR) to treat raw strong leachate from open dumping of municipal solid waste. The influence of two important and effective independent variables, COD concentrations and volumetric filling rate with GAC, onto the leachate treatment were investigated. Three responses such as TKN, BOD and COD were considered for evaluating the interaction of parameters. The results showed that maximum BOD removal of 98.9% in anaerobic zone and 99% in aerobic zone was obtained at the highest values of COD (~30000 mg/L) and filling ratio (~50%). The highest values of COD removal efficiency were found to be 98.54% and 98%, at COD rate of 10000 mg/L and GAC of 35%, respectively. The highest removal values of TKN was 77.2% and 78.9% in anaerobic and aerobic zone, respectively. Under optimal conditions, compared with the SBR and the GAC-SBR performances, results reveal that the application of the GAC-SBR has shown better effluent characteristics. Based on the results, it can be asserted that the application of the high rate IAnA-BioGACSBR for the treatment of biodegradable landfill leachate was more effective.
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http://dx.doi.org/10.1038/s41598-017-02936-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465075PMC
June 2017

Photocatalytic degradation of Aniline from aqueous solutions under sunlight illumination using immobilized Cr:ZnO nanoparticles.

Sci Rep 2017 05 3;7(1):1473. Epub 2017 May 3.

King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

The present study aimed at synthesizing chromium doped zinc oxide nanoparticles (Cr:ZnO NPs) under mild hydrothermal conditions (temperature ~100 °C, p = autogenous and time ~12 hr). Chromium oxide and n-butylamine were used as dopant and surface modifier, respectively. The characteristics of the synthesized nanoparticles were determined through conducting specialized experiments including powder XRD, FTIR, SEM, EDX, and UV-VIS spectroscopy. Then, the Cr:ZnO NPs were immobilized on a sandblasted glass through thermal method. The photocatalytic degradation of aniline was conducted in a continuous reactor with a volume of 1.5 liters. Before and after photocatalytic degradation, the immobilized Cr:ZnO NPs were characterized for SEM and EDX to determine the degree of stability of immobilized nanoparticles as well as the influence of the current applied on them. The photodegradation operational parameters investigated were aniline initial concentration (150, 200, and 250 mg/L), pH (5, 7, 6, and 12), and reaction time (2, 4, and 6 hours) under sunlight illumination. The characterization results indicated high purity of the Cr:ZnO NPs and no change in morphology or composition even after the immobilization and photo-oxidation process. Finally, it was found that the optimum conditions for 93% removal of aniline under sunlight illumination was about 6 hours retention time at pH 9.
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http://dx.doi.org/10.1038/s41598-017-01461-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431250PMC
May 2017

A Review on Nano-Antimicrobials: Metal Nanoparticles, Methods and Mechanisms.

Curr Drug Metab 2017 ;18(2):120-128

King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Nanotechnology is a scientific and engineering technology conducted at the nano-scale, such as in the fields of compound fabric manufacturing, food processing, agricultural processing, and engineering, as well as in medical and medicinal applications. In recent decade, nanomaterial applications for antimicrobial works have of prime interest of by many researchers. Available reports show that some of the metal oxide nanoparticles (NPs) including Al2O3, TiO2, ZnO, CuO, Co3O4, In2O3, MgO, SiO2, ZrO2, Cr2O3, Ni2O3, Mn2O3, CoO, and Nickel oxide have toxicity toward several microorganisms and they could successfully kill numerous bacteria. Based on our literature review there are some effective factors that can influence the ability of nanomaterials in reducing or killing the cells, and there are mechanisms for nanomaterial against bacteria, which are briefly listed as follows: surface charge of the metal nanomaterial, shape, type and material, concentration of nanomaterial, dispersion and contact of nanomaterial to the bacterial cell, presence of active oxygen, liberation of antimicrobial ions, medium components and pH, physicochemical properties, specific surface-area-to-volume ratios, size, role of growth rate, role of biofilm formation, cell wall of bacteria, and effect of UV illumination. It can be considered that in the use of nanomaterials as antimicrobial agents, consideration of many factors remain principal. Antibacterial resistance to common chemical antibacterial agents can be due to long production-consumption cycle, thereby reducing their efficiency, and use of poor quality or fake medicines in undeveloped and developing countries. NPs as antimicrobial agents have become an emerging approach against this challenge, which can establish an effective nanostructure to deliver the antimicrobial agents for targeting the bacterial community efficiently. In addition, they are so potent that microbial pathogens cannot develop resistance to wards them. On the other hand, most of the metal oxide NPs have no toxicity toward humans at effective concentrations used to kill bacterial cells, which thus becomes an advantage for using them in a full scale. However, over the present decade, several studies have suggested that NPs are excellent antibacterial agents, at least at the research level.
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http://dx.doi.org/10.2174/1389200217666161201111146DOI Listing
September 2018