Dr. Hoon-Ki Sung, MD, PhD - SickKids Hospital Research Institute - Scientist

Dr. Hoon-Ki Sung

MD, PhD

SickKids Hospital Research Institute

Scientist

Toronto, Ontario | Canada

Dr. Hoon-Ki Sung, MD, PhD - SickKids Hospital Research Institute - Scientist

Dr. Hoon-Ki Sung

MD, PhD

Introduction

Primary Affiliation: SickKids Hospital Research Institute - Toronto, Ontario , Canada

Publications

32Publications

1067Reads

2Profile Views

1825PubMed Central Citations

Embryonic Stem Cell-Derived mmu-miR-291a-3p Inhibits Cellular Senescence in Human Dermal Fibroblasts Through the TGF-β Receptor 2 Pathway.

J Gerontol A Biol Sci Med Sci 2019 Aug;74(9):1359-1367

Department of Biochemistry and Molecular Biology, College of Medicine, Daegu, Republic of Korea.

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http://dx.doi.org/10.1093/gerona/gly208DOI Listing
August 2019
23 Reads
5.420 Impact Factor

Flow Cytometry and Lineage Tracing Study for Identification of Adipocyte Precursor Cell (APC) Populations.

Methods Mol Biol 2018 ;1752:111-121

Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/978-1-4939-7714-7_11DOI Listing
January 2019
91 Reads

Visualization of 3D White Adipose Tissue Structure Using Whole-mount Staining.

J Vis Exp 2018 11 17(141). Epub 2018 Nov 17.

Translational Medicine Program, The Hospital for Sick Children; Department of Laboratory Medicine and Pathobiology, University of Toronto; Banting and Best Diabetes Centre, University of Toronto;

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https://www.jove.com/video/58683/visualization-3d-white-adip
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http://dx.doi.org/10.3791/58683DOI Listing
November 2018
13 Reads

Visualization of 3D White Adipose Tissue Structure Using Whole-mount Staining.

J Vis Exp 2018 11 17(141). Epub 2018 Nov 17.

Translational Medicine Program, The Hospital for Sick Children; Department of Laboratory Medicine and Pathobiology, University of Toronto; Banting and Best Diabetes Centre, University of Toronto;

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https://www.jove.com/video/58683/visualization-3d-white-adip
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http://dx.doi.org/10.3791/58683DOI Listing
November 2018
13 Reads

Adipose Tissue and Modulation of Hypertension.

Curr Hypertens Rep 2018 09 18;20(11):96. Epub 2018 Sep 18.

Translational Medicine Program, The Hospital for Sick Children Research Institute, Toronto, Ontario, M5G 0A4, Canada.

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http://dx.doi.org/10.1007/s11906-018-0894-7DOI Listing
September 2018
9 Reads
3.440 Impact Factor

Generation of Induced Progenitor-like Cells from Mature Epithelial Cells Using Interrupted Reprogramming.

Stem Cell Reports 2017 12 30;9(6):1780-1795. Epub 2017 Nov 30.

Division of Thoracic Surgery, Toronto General Hospital Research Institute, University Health Network, University of Toronto, Toronto, ON M5G 2C4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785620PMC
December 2017
20 Reads
1 Citation

Collection of Serum- and Feeder-free Mouse Embryonic Stem Cell-conditioned Medium for a Cell-free Approach.

J Vis Exp 2017 01 8(119). Epub 2017 Jan 8.

Department of Biochemistry and Molecular Biology and Smart-aging Convergence Research Center, College of Medicine, Yeungnam University;

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http://dx.doi.org/10.3791/55035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408645PMC
January 2017
12 Reads

Antisenescence effect of mouse embryonic stem cell conditioned medium through a PDGF/FGF pathway.

FASEB J 2016 Mar 16;30(3):1276-86. Epub 2015 Dec 16.

*Department of Biochemistry and Molecular Biology, Smart-Aging Convergence Research Center, and Department of Pathology, College of Medicine, Yeungnam University, Daegu, Republic of Korea; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada; and Physiology and Experimental Medicine Program, Hospital for Sick Children Research Institute, Toronto, Ontario, Canada

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http://dx.doi.org/10.1096/fj.15-278846DOI Listing
March 2016
39 Reads
3 Citations
5.043 Impact Factor

Generation, Characterization, and Multilineage Potency of Mesenchymal-Like Progenitors Derived from Equine Induced Pluripotent Stem Cells.

Stem Cells Dev 2016 Jan 5;25(1):80-9. Epub 2015 Nov 5.

1 Department of Biomedical Sciences, University of Guelph , Guelph, Ontario, Canada .

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https://www.liebertpub.com/doi/10.1089/scd.2014.0409
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http://dx.doi.org/10.1089/scd.2014.0409DOI Listing
January 2016
32 Reads
4 Citations
3.730 Impact Factor

iPS cell-derived cardiogenicity is hindered by sustained integration of reprogramming transgenes.

Circ Cardiovasc Genet 2014 Oct 30;7(5):667-76. Epub 2014 Jul 30.

From the Center for Regenerative Medicine (A.M.-F., T.J.N., S.R., A.E.A., A.T.), Marriott Heart Disease Research Program, Division of Cardiovascular Diseases (A.M.-F., S.R., A.E.A., A.T.), and Department of Physical Medicine and Rehabilitation (C.P.-T.), General Internal Medicine and Transplant Center (T.J.N., F.S., R.B.), Mayo Clinic, Rochester, MN; and Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada (H.-K.S., A.N.).

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https://www.ahajournals.org/doi/10.1161/CIRCGENETICS.113.000
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http://dx.doi.org/10.1161/CIRCGENETICS.113.000298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273857PMC
October 2014
46 Reads
2 Citations
5.340 Impact Factor

Trophoblast-specific reduction of VEGFA alters placental gene expression and maternal cardiovascular function in mice.

Biol Reprod 2014 Oct 13;91(4):87. Epub 2014 Aug 13.

Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada Department of Physiology, University of Toronto, Toronto, Ontario, Canada Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada

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http://dx.doi.org/10.1095/biolreprod.114.118299DOI Listing
October 2014
24 Reads
3 Citations
3.320 Impact Factor

VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy.

EMBO Mol Med 2013 Sep 2;5(9):1415-30. Epub 2013 Aug 2.

Laboratory of Vascular Biology and Stem Cells and Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.

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http://dx.doi.org/10.1002/emmm.201302618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799495PMC
September 2013
55 Reads
23 Citations
8.665 Impact Factor

Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis.

Cell Metab 2013 Jan;17(1):61-72

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON M5T 3H7, Canada.

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http://dx.doi.org/10.1016/j.cmet.2012.12.010DOI Listing
January 2013
12 Reads
68 Citations
17.570 Impact Factor

Highly efficient site-specific transgenesis in cancer cell lines.

Mol Cancer 2012 Dec 11;11:89. Epub 2012 Dec 11.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, M5G 1X5, Canada.

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http://dx.doi.org/10.1186/1476-4598-11-89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537676PMC
December 2012
34 Reads
3 Citations
4.260 Impact Factor

Induced pluripotent stem cell lines derived from equine fibroblasts.

Stem Cell Rev Rep 2011 Sep;7(3):693-702

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s12015-011-9239-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137777PMC
September 2011
43 Reads
43 Citations
2.770 Impact Factor

An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.

Cell 2011 Sep 15;147(1):132-46. Epub 2011 Sep 15.

Banting and Best Department of Medical Research, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.

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http://dx.doi.org/10.1016/j.cell.2011.08.023DOI Listing
September 2011
19 Reads
112 Citations
32.242 Impact Factor

Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.

Cell Stem Cell 2010 Jul 17;7(1):64-77. Epub 2010 Jun 17.

Center for Systems Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.

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http://dx.doi.org/10.1016/j.stem.2010.04.015DOI Listing
July 2010
39 Reads
333 Citations

Multifaceted role of vascular endothelial growth factor signaling in adult tissue physiology: an emerging concept with clinical implications.

Curr Opin Hematol 2010 May;17(3):206-12

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MOH.0b013e32833865e6DOI Listing
May 2010
8 Reads
9 Citations
3.970 Impact Factor

COMP-angiopoietin-1 enhances skeletal muscle blood flow and insulin sensitivity in mice.

Am J Physiol Endocrinol Metab 2009 Aug 2;297(2):E402-9. Epub 2009 Jun 2.

Department of Biological Science, Korea Advanced Institute of Science and Technology, Biomedical Research Center, Daejeon, South Korea.

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http://dx.doi.org/10.1152/ajpendo.00122.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056742PMC
August 2009
33 Reads
7 Citations
3.790 Impact Factor

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells.

Nature 2009 Apr 1;458(7239):766-70. Epub 2009 Mar 1.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.

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http://dx.doi.org/10.1038/nature07863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758996PMC
April 2009
38 Reads
516 Citations
42.351 Impact Factor

Lymphatic development in mouse small intestine.

Dev Dyn 2007 Jul;236(7):2020-5

National Research Laboratory of Vascular Biology and Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Korea.

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http://dx.doi.org/10.1002/dvdy.21200DOI Listing
July 2007
6 Reads
17 Citations
2.380 Impact Factor

Angiogenic role of LYVE-1-positive macrophages in adipose tissue.

Circ Res 2007 Mar 1;100(4):e47-57. Epub 2007 Feb 1.

National Research Laboratory of Vascular Biology and Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea.

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http://dx.doi.org/10.1161/01.RES.0000259564.92792.93DOI Listing
March 2007
41 Reads
77 Citations
11.020 Impact Factor

Intestinal and peri-tumoral lymphatic endothelial cells are resistant to radiation-induced apoptosis.

Biochem Biophys Res Commun 2006 Jun 2;345(2):545-51. Epub 2006 May 2.

Biomedical Research Center and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2006.04.121DOI Listing
June 2006
13 Reads
5 Citations
2.300 Impact Factor

COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model.

Proc Natl Acad Sci U S A 2006 Mar 16;103(13):4946-51. Epub 2006 Mar 16.

Biomedical Research Center and Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Guseong-dong, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1073/pnas.0506352103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458775PMC
March 2006
40 Reads
40 Citations
9.810 Impact Factor

Top co-authors

Andras Nagy
Andras Nagy

Mount Sinai Hospital

21
Gou Young Koh
Gou Young Koh

Graduate School of Medical Science and Engineering

8
Iacovos P Michael
Iacovos P Michael

Mount Sinai Hospital

6
Jae-Ryong Kim
Jae-Ryong Kim

Yeungnam University

5
Knut Woltjen
Knut Woltjen

Kyoto University

5
Ju Hee Lee
Ju Hee Lee

Yonsei University College of Medicine

5
Kristina Nagy
Kristina Nagy

Mount Sinai Hospital

4
Puzheng Zhang
Puzheng Zhang

Mount Sinai Hospital

4
Yun-Ui Bae
Yun-Ui Bae

Kyungpook National University

3
Claudio Monetti
Claudio Monetti

Università dell'Insubria

3