Publications by authors named "Hongming Cao"

3 Publications

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High-throughput sequencing and analysis of microbial communities in the mangrove swamps along the coast of Beibu Gulf in Guangxi, China.

Sci Rep 2019 06 28;9(1):9377. Epub 2019 Jun 28.

The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, 350117, China.

Mangrove swamp is one of the world's richest and most productive marine ecosystems. This ecosystem also has a great ecological importance, but is highly susceptible to anthropogenic disturbances. The balance of mangrove ecosystem depends largely on the microbial communities in mangrove sediments. Thus, understanding how the mangrove microbial communities respond to spatial differences is essential for more accurate assessment of mangrove ecosystem health. To this end, we performed the first medium-distance (150 km) research on the biogeographic distribution of mangrove microbial communities. The hypervariable regions of 16S rRNA gene was sequenced by Illumina to compare the microbial communities in mangrove sediments collected from six locations (i.e. Zhenzhu harbor, Yuzhouping, Maowei Sea, Qinzhou harbor, Beihai city and Shankou) along the coastline of Beibu Gulf in Guangxi province, China. Collectively, Proteobacteria, Bacteroidetes, Chloroflexi, Actinobacteria, Parvarchaeota, Acidobacteria and Cyanobacteria were the predominant phyla in the mangrove sediments of this area. At genus level, the heat map of microbial communities reflected similarities between study sites and was in agreement with their biogeographic characteristics. Interestingly, the genera Desulfococcus, Arcobacter, Nitrosopumilus and Sulfurimonas showed differences in abundance between study sites. Furthermore, the principal component analysis (PCA) and unweighted UniFrac cluster tree of beta diversity were used to study the biogeographic diversity of the microbial communities. Relatively broader variation of microbial communities was found in Beihai city and Qinzhou harbour, suggesting that environmental condition and historical events may play an important role in shaping the bacterial communities as well. This is the first report on medium-distance range distribution of bacteria in the mangrove swamp ecosystem. Our data is valuable for monitoring and evaluation of the impact of human activity on mangrove habitats from the perspective of microbiome.
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http://dx.doi.org/10.1038/s41598-019-45804-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599077PMC
June 2019

Synthesis and optical properties of SnO(2) nanorods.

Nanotechnology 2008 Mar 12;19(9):095708. Epub 2008 Feb 12.

Well-crystalline SnO(2) nanorods have been synthesized successfully via a lithium-assisted solution-phase method. The structural and optical properties of the SnO(2) nanorods were investigated using x-ray powder diffraction, transmission electron microscopy, high-resolution transmission electron microscopy, and infrared, Raman and photoluminescence spectroscopy. The experimental results show that lithium addition plays a critical role in the formation of SnO(2) nanorods, and the correlation between the surface energy change and morphological evolution of this material is also discussed. This approach provides an economically viable route for large-scale synthesis of this nanostructured material.
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http://dx.doi.org/10.1088/0957-4484/19/9/095708DOI Listing
March 2008

Novel silica-coated iron-carbon composite particles and their targeting effect as a drug carrier.

J Biomed Mater Res A 2008 Sep;86(3):671-7

Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, People's Republic of China.

Novel silica-coated iron-carbon composite particles were prepared to be used in the targeting therapy as a drug carrier. The composite particles with diameter of 200-300 nm were obtained successfully via high-energy planetary ball milling and hydrogen reduction processes. The composite particles possess the advantages of activated carbon and magnetic Fe, exhibiting excellent drug adsorption and desorption abilities as well as powerfully magnetic targeting. In in vivo experiment, (99m)TcO(4)-adsorbed composite particles showed prominent biodistribution in the left hepatic lobe of pigs under the control of an external magnetic field. The amount of doxorubicin content of hepatic tissue was 23.8 times higher in targeted area of the left lobe than that in the nontargeted area of the right lobe when doxorubicin-adsorbed composite particles were infused intra-arterially. These results also suggest that the composite particles could penetrate through the capillary wall around tissue interstitium and hepatic cells under the driving of an external magnetic force in targeting area, indicating that the novel silica-coated iron-carbon composite particles could be a potential application in targeted treatment for some kinds of tumor as an effective drug carrier.
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http://dx.doi.org/10.1002/jbm.a.31647DOI Listing
September 2008
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