Publications by authors named "Hongdo Do"

46Publications

NTRK and ALK rearrangements in malignant pleural mesothelioma, pulmonary neuroendocrine tumours and non-small cell lung cancer.

Lung Cancer 2020 08 24;146:154-159. Epub 2020 May 24.

Department of Medical Oncology, Austin Health, Olivia Newton-John Cancer and Wellness Centre, Heidelberg, Victoria, Australia; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.05.019DOI Listing
August 2020

Adapting an Established Clinical Chemistry Quality Control Measure for Droplet Generation Performance in Digital PCR.

Clin Chem 2018 08 11;64(8):1255-1257. Epub 2018 Jun 11.

Translational Genomics and Epigenomics Laboratory Olivia Newton-John Cancer Research Institute Heidelberg, Victoria, Australia

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http://dx.doi.org/10.1373/clinchem.2018.291120DOI Listing
August 2018

Somatic mutation in the of Sturge-Weber syndrome.

Neurol Genet 2018 Jun 1;4(3):e236. Epub 2018 May 1.

Department of Medicine (Austin Hospital) (M.S.H., J.A.D., Z.Y., L.M., I.E.S., S.F.B.), University of Melbourne, Heidelberg, Victoria, Australia; Murdoch Childrens Research Institute (M.S.H., A.S.H., G.G., K.P., P.J.L., R.J.L.), Parkville, Victoria, Australia; Department of Paediatrics (Royal Children's Hospital) (A.S.H., G.G., K.P., P.J.L., R.J.L., I.E.S.), Department of Pathology (H.D., R.K., A.D), and Department of Medicine (Royal Melbourne Hospital) (E.O., N.C.J.), University of Melbourne, Parkville, Victoria, Australia; Department of Neurology (A.S.H., R.J.L., I.E.S.) and Department of Neurosurgery (W.M.), Royal Children's Hospital, Parkville, Victoria, Australia; Department of Neurosciences (S.M., B.N.) and Neurosurgical Department (M.W.), Lady Cilento Children's Hospital, Brisbane, Queensland, Australia; Translational Genomics and Epigenomics Laboratory (H.D., A.D.), Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine (H.D., A.D.), La Trobe University, Bundoora, Victoria, Australia; Anatomical Pathology (R.K.), Austin Health, Heidelberg, Victoria, Australia; Department of Neuroscience (N.C.J.), Central Clinical School, Monash University, Victoria, Australia; and Department of Neurology (N.C.J.), The Alfred Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1212/NXG.0000000000000236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931068PMC
June 2018

In Reply to Leone.

J Thorac Oncol 2018 02;13(2):e22-e23

Olivia Newton-John Cancer and Wellness Center, Heidelberg, Melbourne, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.jtho.2017.11.119DOI Listing
February 2018

Sensitive quantitative detection of somatic mosaic mutation in "double cortex" syndrome.

Epileptic Disord 2017 Dec;19(4):450-455

Epilepsy Research Centre, Department of Medicine, University of Melbourne, Austin Health, Heidelberg, VIC.

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http://dx.doi.org/10.1684/epd.2017.0944DOI Listing
December 2017

GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly.

Genome Res 2017 12 2;27(12):2050-2060. Epub 2017 Nov 2.

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.

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http://dx.doi.org/10.1101/gr.222109.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741059PMC
December 2017

Interlaboratory Reproducibility of Droplet Digital Polymerase Chain Reaction Using a New DNA Reference Material Format.

Anal Chem 2017 11 18;89(21):11243-11251. Epub 2017 Oct 18.

National Measurement Institute (NMI) , Lindfield, Sydney, New South Wales 2070, Australia.

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http://dx.doi.org/10.1021/acs.analchem.6b05032DOI Listing
November 2017

De novo activating epidermal growth factor mutations (EGFR) in small-cell lung cancer.

Intern Med J 2017 Sep;47(9):1071-1074

Department of Medical Oncology, Austin Health, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/imj.13531DOI Listing
September 2017

EGFR and KRAS mutations do not enrich for the activation of IL-6, JAK1 or phosphorylated STAT3 in resected lung adenocarcinoma.

Med Oncol 2017 Sep 6;34(10):175. Epub 2017 Sep 6.

Department of Medicine, St Vincent's Hospital, Melbourne Medical School, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1007/s12032-017-1031-1DOI Listing
September 2017

Combination Osimertinib and Gefitinib in C797S and T790M EGFR-Mutated Non-Small Cell Lung Cancer.

J Thorac Oncol 2017 11 24;12(11):1728-1732. Epub 2017 Aug 24.

Cancer Immunobiology Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia; Department of Medical Oncology, Olivia Newton-John Cancer and Wellness Centre, Austin Health, Heidelberg, Victoria, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864173068
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http://dx.doi.org/10.1016/j.jtho.2017.08.006DOI Listing
November 2017

Reducing Artifactual T790M Mutations in DNA from Formalin-Fixed Paraffin-Embedded Tissue by Use of Thymine-DNA Glycosylase.

Clin Chem 2017 Sep 18;63(9):1506-1514. Epub 2017 Jul 18.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia;

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http://dx.doi.org/10.1373/clinchem.2017.271932DOI Listing
September 2017

Probe-Free Digital PCR Quantitative Methodology to Measure Donor-Specific Cell-Free DNA after Solid-Organ Transplantation.

Clin Chem 2017 03 18;63(3):742-750. Epub 2017 Jan 18.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia;

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http://dx.doi.org/10.1373/clinchem.2016.264838DOI Listing
March 2017

Digital PCR of Genomic Rearrangements for Monitoring Circulating Tumour DNA.

Adv Exp Med Biol 2016 ;924:139-146

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, VIC, 3084, Australia.

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http://dx.doi.org/10.1007/978-3-319-42044-8_27DOI Listing
September 2017

Temporal changes of EGFR mutations and T790M levels in tumour and plasma DNA following AZD9291 treatment.

Lung Cancer 2016 08 11;98:29-32. Epub 2016 May 11.

Department of Medical Oncology, Austin Health, Melbourne, Australia; Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.lungcan.2016.05.003DOI Listing
August 2016

Comparison of 3 Methodologies for Genotyping of Small Deletion and Insertion Polymorphisms.

Clin Chem 2016 Jul;62(7):1012-9

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Victoria, Australia; Department of Pathology, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1373/clinchem.2016.256388DOI Listing
July 2016

Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization.

Clin Chem 2015 Jan 24;61(1):64-71. Epub 2014 Nov 24.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; Department of Pathology, University of Melbourne, Parkville, Victoria, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.

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http://dx.doi.org/10.1373/clinchem.2014.223040DOI Listing
January 2015

Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver.

Clin Cancer Res 2014 Dec 14;20(24):6618-30. Epub 2014 Oct 14.

Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia. Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, New South Wales, Australia. University of Sydney, Westmead Hospital, Sydney, New South Wales, Australia. Westmead Institute for Cancer Research, Westmead Millennium Institute, Westmead Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1292DOI Listing
December 2014

Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine.

Oncotarget 2014 Apr;5(8):2107-15

Translational Genomics and Epigenomics Laboratory Ludwig Institute for Cancer Research Olivia Newton-John Cancer and Wellness Centre Heidelberg, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039149PMC
http://dx.doi.org/10.18632/oncotarget.1840DOI Listing
April 2014

The clinical relevance of pathologic subtypes in metastatic lung adenocarcinoma.

J Thorac Oncol 2014 May;9(5):654-63

*Department of Medical Oncology, St. Vincent's Hospital, Melbourne; †Department of Medicine, University of Melbourne; ‡Translational Genomics and Epigenomics Laboratory, Ludwig Institute for Cancer Research, Olivia Newton John Cancer and Wellness Centre, Heidelberg; §Department of Pathology, University of Melbourne; ‖Department of Medicine, Eastern Hill Academic Centre, Melbourne Medical School, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne; ¶Department of Respiratory Medicine, St. Vincent's Hospital; #Department of Thoracic Surgery, St. Vincent's Hospital, Melbourne; **Department of Surgery, University of Melbourne; and ††Department of Anatomical Pathology, St. Vincent's Hospital, Melbourne, Australia.

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http://dx.doi.org/10.1097/JTO.0000000000000150DOI Listing
May 2014

A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma.

Sci Rep 2014 Feb 26;4:4186. Epub 2014 Feb 26.

1] Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, 8006, Australia [2] Translational Genomics and Epigenomics Laboratory, Ludwig Institute for Medical Research, Olivia Newton-John Cancer and Wellness Centre, Austin Hospital, Heidelberg, Victoria, 3084, Australia [3] Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, 3010, Australia [4] Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Victoria, 8006, Australia [5] Department of Pathology, University of Melbourne, Parkville, Victoria, 3010, Australia.

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http://dx.doi.org/10.1038/srep04186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935198PMC
February 2014

Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome.

Int J Cancer 2014 Aug 30;135(4):887-95. Epub 2014 Jan 30.

Department of Medical Oncology, Peter MacCallum Cancer Centre, East Melbourne, Australia; University of Melbourne, Australia; Research Division, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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http://dx.doi.org/10.1002/ijc.28727DOI Listing
August 2014

Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome.

Clin Epigenetics 2014 9;6(1):22. Epub 2014 Dec 9.

Translational Genomics and Epigenomics Laboratory, Ludwig Institute for Cancer Research, Olivia Newton-John Cancer & Wellness Centre, Austin Health, 145-163 Studley Road, Heidelberg, Victoria 3084 Australia ; Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1 A'Beckett Street, Melbourne, Victoria 8006 Australia ; Department of Pathology, The University of Melbourne, Parkville, Victoria 3010 Australia ; School of Cancer Medicine, La Trobe University, Bundoora, Victoria 3084 Australia.

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http://europepmc.org/articles/PMC4391486
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https://www.researchgate.net/publication/305388481_Genome-sc
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http://clinicalepigeneticsjournal.biomedcentral.com/articles
Publisher Site
http://dx.doi.org/10.1186/1868-7083-6-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391486PMC
April 2015

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours.

Sci Rep 2013 Dec 13;3:3494. Epub 2013 Dec 13.

1] Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, Victoria, 3002, Australia [2] Department of Pathology, The University of Melbourne, Parkville, Victoria, 3010, Australia [3] Translational Genomics and Epigenomics Laboratory, Ludwig Institute for Cancer Research, The Olivia Newton-John Cancer and Wellness Centre, Heidelberg, Victoria, 3084, Australia.

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http://dx.doi.org/10.1038/srep03494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861801PMC
December 2013

EGFR gene copy number alterations are not a useful screening tool for predicting EGFR mutation status in lung adenocarcinoma.

Pathology 2014 Jan;46(1):32-6

1Department of Anatomical Pathology, St Vincent's Hospital, University of Melbourne, Fitzroy 2Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne 3Department of Medical Oncology, St Vincent's Hospital, University of Melbourne, Fitzroy 4University of Melbourne Department of Surgery, St Vincent's Hospital, Fitzroy 5Department of Respiratory and Sleep Medicine, St Vincent's Hospital, University of Melbourne, Fitzroy, Victoria, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S00313025163063
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http://dx.doi.org/10.1097/PAT.0000000000000027DOI Listing
January 2014

BRAF inhibitor-driven tumor proliferation in a KRAS-mutated colon carcinoma is not overcome by MEK1/2 inhibition.

J Clin Oncol 2013 Dec 4;31(35):e448-51. Epub 2013 Nov 4.

Joint Ludwig-Austin Oncology Unit, Austin Health, Victoria, Australia.

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http://dx.doi.org/10.1200/JCO.2013.50.4118DOI Listing
December 2013

Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors.

BMC Med Genomics 2013 Oct 11;6:40. Epub 2013 Oct 11.

Cancer Immuno-biology Lab, Ludwig Institute for Cancer Research Melbourne, Austin Branch, Melbourne, Victoria 3084, Australia.

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http://dx.doi.org/10.1186/1755-8794-6-40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852494PMC
October 2013

Reducing sequence artifacts in amplicon-based massively parallel sequencing of formalin-fixed paraffin-embedded DNA by enzymatic depletion of uracil-containing templates.

Clin Chem 2013 Sep 6;59(9):1376-83. Epub 2013 May 6.

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1373/clinchem.2012.202390DOI Listing
September 2013

DNA methylation biomarkers in cancer: progress towards clinical implementation.

Expert Rev Mol Diagn 2012 Jun;12(5):473-87

Molecular Pathology Research & Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett Street, Melbourne, Victoria 8006, Australia.

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http://dx.doi.org/10.1586/erm.12.45DOI Listing
June 2012

Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil- DNA glycosylase.

Oncotarget 2012 May;3(5):546-58

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388184PMC
http://dx.doi.org/10.18632/oncotarget.503DOI Listing
May 2012

Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies.

Mol Cancer 2009 Oct 8;8:82. Epub 2009 Oct 8.

Department of Pathology, University of Melbourne, Parkville, Victoria, 3010, Australia.

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http://dx.doi.org/10.1186/1476-4598-8-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766370PMC
October 2009

Detection of the transforming AKT1 mutation E17K in non-small cell lung cancer by high resolution melting.

BMC Res Notes 2008 May 16;1:14. Epub 2008 May 16.

Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St, Melbourne, Victoria, 8006, Australia.

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http://dx.doi.org/10.1186/1756-0500-1-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442881PMC
May 2008

High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies.

BMC Cancer 2008 May 21;8:142. Epub 2008 May 21.

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St, Melbourne, Victoria 8006, Australia.

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http://dx.doi.org/10.1186/1471-2407-8-142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408599PMC
May 2008