Publications by authors named "Hong Ping Guan"

17Publications

Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.

ACS Med Chem Lett 2018 Jan 1;9(1):39-44. Epub 2017 Dec 1.

Medicinal Chemistry, PPDM Preclinical ADME, In Vitro Pharmacology, In Vivo Pharmacology, and Biology-Discovery Departments, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.

View Article and Find Full Text PDF
January 2018

Factors affecting insulin-regulated hepatic gene expression.

Prog Mol Biol Transl Sci 2014 ;121:165-215

Department of Nutrition, University of Tennessee at Knoxville, Knoxville, Tennessee, USA.

View Article and Find Full Text PDF
July 2014

Accelerated fatty acid oxidation in muscle averts fasting-induced hepatic steatosis in SJL/J mice.

J Biol Chem 2009 Sep 6;284(36):24644-52. Epub 2009 Jul 6.

Department of Molecular Genetics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9046, USA.

View Article and Find Full Text PDF
September 2009

PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.

Am J Physiol Endocrinol Metab 2007 Dec 11;293(6):E1736-45. Epub 2007 Sep 11.

Div. of Endocrinology and Metabolism, Dept. of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave., Boston, MA 02215, USA.

View Article and Find Full Text PDF
December 2007

Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha.

Cell Metab 2005 May;1(5):297-308

Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

View Article and Find Full Text PDF
May 2005

PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1.

J Clin Invest 2005 Aug 7;115(8):2244-56. Epub 2005 Jul 7.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, and The Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6149, USA.

View Article and Find Full Text PDF
August 2005

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

Genes Dev 2005 Feb 28;19(4):453-61. Epub 2005 Jan 28.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The Penn Diabetes Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

View Article and Find Full Text PDF
February 2005

Synphilin in normal human brains and in synucleinopathies: studies with new antibodies.

Acta Neuropathol 2003 Feb 12;105(2):177-84. Epub 2002 Nov 12.

Center for Neurodegenerative Research, Department of Pathology and Laboratory Medicine and Institute on Aging, University of Pennsylvania, Maloney 3, HUP, 3600 Spruce St., Philadelphia 19104, USA.

View Article and Find Full Text PDF
February 2003

A futile metabolic cycle activated in adipocytes by antidiabetic agents.

Nat Med 2002 Oct 23;8(10):1122-8. Epub 2002 Sep 23.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine and The Penn Diabetes Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

View Article and Find Full Text PDF
October 2002