Publications by authors named "Hong Hwa Lim"

20Publications

Emerging Roles of Downstream of Kinase 3 in Cell Signaling.

Front Immunol 2020 29;11:566192. Epub 2020 Sep 29.

Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore, Singapore.

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September 2020

Dun1, a Chk2-related kinase, is the central regulator of securin-separase dynamics during DNA damage signaling.

Nucleic Acids Res 2020 06;48(11):6092-6107

Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Proteos, 61 Biopolis Drive, Singapore.

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June 2020

Mapping Mitotic Death: Functional Integration of Mitochondria, Spindle Assembly Checkpoint and Apoptosis.

Front Cell Dev Biol 2018 10;6:177. Epub 2019 Jan 10.

Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.

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January 2019

Electron cryotomography analysis of Dam1C/DASH at the kinetochore-spindle interface in situ.

J Cell Biol 2019 02 30;218(2):455-473. Epub 2018 Nov 30.

Department of Biological Sciences and Centre for BioImaging Sciences, National University of Singapore, Singapore

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February 2019

Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket.

Chem Sci 2018 Jun 16;9(23):5212-5222. Epub 2018 May 16.

Bioinformatics Institute (BII) , ASTAR , 30 Biopolis Street, 07-01 Matrix , Singapore 138671 . Email: ; Email: ; ; Tel: +65 6478 8353 ; Tel: +65 6478 8273.

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June 2018

Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo.

Mol Biol Cell 2016 11 7;27(21):3357-3368. Epub 2016 Sep 7.

Department of Biological Sciences and Centre for BioImaging Sciences, National University of Singapore, Singapore 117543, Singapore

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November 2016

Chaperoning HMGA2 protein protects stalled replication forks in stem and cancer cells.

Cell Rep 2014 Feb 6;6(4):684-97. Epub 2014 Feb 6.

School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore. Electronic address:

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February 2014

Staging a recovery from mitotic arrest: Unusual ways of Cdk1.

Bioarchitecture 2012 Feb;2(2):33-37

Institute of Molecular and Cell Biology; Proteos, Singapore.

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February 2012

TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation.

J Cell Sci 2012 Mar 10;125(Pt 6):1579-90. Epub 2012 Feb 10.

Division of Molecular Genetics and Cell Biology, School of Biological Sciences, College of Science, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.

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March 2012

Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest.

EMBO J 2012 Jan 4;31(2):403-16. Epub 2011 Nov 4.

Institute of Molecular and Cell Biology, A STAR (Agency for Science Technology and Research), Singapore.

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January 2012

The "suppressive side" of yeast mitotic cyclins.

Cell Cycle 2011 Sep 15;10(18):3052. Epub 2011 Sep 15.

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September 2011

DNA damage checkpoint maintains CDH1 in an active state to inhibit anaphase progression.

Dev Cell 2009 Oct;17(4):541-51

Institute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology and Research) 61, Biopolis Drive, Proteos, Singapore 138673.

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October 2009

Regulation of centrosome separation in yeast and vertebrates: common threads.

Trends Cell Biol 2009 Jul 1;19(7):325-33. Epub 2009 Jul 1.

Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Proteos, 138673 Singapore.

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July 2009

Consorting kinases, end of destruction and birth of a spindle.

Cell Cycle 2008 Oct 13;7(19):2960-6. Epub 2008 Oct 13.

Institute of Molecular and Cell Biology, A *STAR, 61, Biopolis Drive, Proteos, Singapore, Singapore.

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October 2008

Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle.

Nat Cell Biol 2008 Jun 25;10(6):665-75. Epub 2008 May 25.

Institute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology and Research), 61, Biopolis Drive, Proteos, Singapore.

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June 2008

Deficiency of centromere-associated protein Slk19 causes premature nuclear migration and loss of centromeric elasticity.

J Cell Sci 2006 Feb;119(Pt 3):519-31

Institute of Molecular and Cell Biology, Proteos, 61 Biopolis Drive, Singapore 138673.

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February 2006

Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast.

Mol Biol Cell 2003 Nov 22;14(11):4734-43. Epub 2003 Aug 22.

Institute of Molecular and Cell Biology, Singapore 117609.

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November 2003

Tome-1, wee1, and the onset of mitosis: coupled destruction for timely entry.

Mol Cell 2003 Apr;11(4):845-6

Institute of Molecular and Cell Biology, 30 Medical Drive, Singapore 117609, Republic of Singapore.

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April 2003

MEN, destruction and separation: mechanistic links between mitotic exit and cytokinesis in budding yeast.

Bioessays 2002 Jul;24(7):659-66

Institute of Molecular and Cell Biology, 30 Medical Drive, Singapore 117609. [corrected]

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July 2002