Hon-Cheong So

Hon-Cheong So

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Hon-Cheong So

Hon-Cheong So

Publications by authors named "Hon-Cheong So"

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28Publications

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Exploring shared genetic bases and causal relationships of schizophrenia and bipolar disorder with 28 cardiovascular and metabolic traits.

Psychol Med 2019 Jun 26;49(8):1286-1298. Epub 2018 Jul 26.

Department of Psychiatry,University of Hong Kong,Pokfulam,Hong Kong.

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http://dx.doi.org/10.1017/S0033291718001812DOI Listing
June 2019

Using Drug Expression Profiles and Machine Learning Approach for Drug Repurposing.

Methods Mol Biol 2019 ;1903:219-237

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1007/978-1-4939-8955-3_13DOI Listing
June 2019

Drug Repositioning for Schizophrenia and Depression/Anxiety Disorders: A Machine Learning Approach Leveraging Expression Data.

IEEE J Biomed Health Inform 2019 05 16;23(3):1304-1315. Epub 2018 Jul 16.

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http://dx.doi.org/10.1109/JBHI.2018.2856535DOI Listing
May 2019

Differential associations of depression-related phenotypes with cardiometabolic risks: Polygenic analyses and exploring shared genetic variants and pathways.

Depress Anxiety 2019 04 6;36(4):330-344. Epub 2018 Dec 6.

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.

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http://dx.doi.org/10.1002/da.22861DOI Listing
April 2019

Implications of de novo mutations in guiding drug discovery: A study of four neuropsychiatric disorders.

J Psychiatr Res 2019 Mar 14;110:83-92. Epub 2018 Dec 14.

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China.

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https://linkinghub.elsevier.com/retrieve/pii/S00223956183087
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http://dx.doi.org/10.1016/j.jpsychires.2018.12.015DOI Listing
March 2019

Leveraging genome-wide association and clinical data in revealing schizophrenia subgroups.

J Psychiatr Res 2018 11 22;106:106-117. Epub 2018 Sep 22.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong; KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research of Common Diseases, Kunming Zoology Institute of Zoology and the Chinese University of Hong Kong, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00223956183041
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http://dx.doi.org/10.1016/j.jpsychires.2018.09.010DOI Listing
November 2018

Analysis of shared heritability in common disorders of the brain.

Authors:
Verneri Anttila Brendan Bulik-Sullivan Hilary K Finucane Raymond K Walters Jose Bras Laramie Duncan Valentina Escott-Price Guido J Falcone Padhraig Gormley Rainer Malik Nikolaos A Patsopoulos Stephan Ripke Zhi Wei Dongmei Yu Phil H Lee Patrick Turley Benjamin Grenier-Boley Vincent Chouraki Yoichiro Kamatani Claudine Berr Luc Letenneur Didier Hannequin Philippe Amouyel Anne Boland Jean-François Deleuze Emmanuelle Duron Badri N Vardarajan Christiane Reitz Alison M Goate Matthew J Huentelman M Ilyas Kamboh Eric B Larson Ekaterina Rogaeva Peter St George-Hyslop Hakon Hakonarson Walter A Kukull Lindsay A Farrer Lisa L Barnes Thomas G Beach F Yesim Demirci Elizabeth Head Christine M Hulette Gregory A Jicha John S K Kauwe Jeffrey A Kaye James B Leverenz Allan I Levey Andrew P Lieberman Vernon S Pankratz Wayne W Poon Joseph F Quinn Andrew J Saykin Lon S Schneider Amanda G Smith Joshua A Sonnen Robert A Stern Vivianna M Van Deerlin Linda J Van Eldik Denise Harold Giancarlo Russo David C Rubinsztein Anthony Bayer Magda Tsolaki Petra Proitsi Nick C Fox Harald Hampel Michael J Owen Simon Mead Peter Passmore Kevin Morgan Markus M Nöthen Martin Rossor Michelle K Lupton Per Hoffmann Johannes Kornhuber Brian Lawlor Andrew McQuillin Ammar Al-Chalabi Joshua C Bis Agustin Ruiz Mercè Boada Sudha Seshadri Alexa Beiser Kenneth Rice Sven J van der Lee Philip L De Jager Daniel H Geschwind Matthias Riemenschneider Steffi Riedel-Heller Jerome I Rotter Gerhard Ransmayr Bradley T Hyman Carlos Cruchaga Montserrat Alegret Bendik Winsvold Priit Palta Kai-How Farh Ester Cuenca-Leon Nicholas Furlotte Tobias Kurth Lannie Ligthart Gisela M Terwindt Tobias Freilinger Caroline Ran Scott D Gordon Guntram Borck Hieab H H Adams Terho Lehtimäki Juho Wedenoja Julie E Buring Markus Schürks Maria Hrafnsdottir Jouke-Jan Hottenga Brenda Penninx Ville Artto Mari Kaunisto Salli Vepsäläinen Nicholas G Martin Grant W Montgomery Mitja I Kurki Eija Hämäläinen Hailiang Huang Jie Huang Cynthia Sandor Caleb Webber Bertram Muller-Myhsok Stefan Schreiber Veikko Salomaa Elizabeth Loehrer Hartmut Göbel Alfons Macaya Patricia Pozo-Rosich Thomas Hansen Thomas Werge Jaakko Kaprio Andres Metspalu Christian Kubisch Michel D Ferrari Andrea C Belin Arn M J M van den Maagdenberg John-Anker Zwart Dorret Boomsma Nicholas Eriksson Jes Olesen Daniel I Chasman Dale R Nyholt Andreja Avbersek Larry Baum Samuel Berkovic Jonathan Bradfield Russell J Buono Claudia B Catarino Patrick Cossette Peter De Jonghe Chantal Depondt Dennis Dlugos Thomas N Ferraro Jacqueline French Helle Hjalgrim Jennifer Jamnadas-Khoda Reetta Kälviäinen Wolfram S Kunz Holger Lerche Costin Leu Dick Lindhout Warren Lo Daniel Lowenstein Mark McCormack Rikke S Møller Anne Molloy Ping-Wing Ng Karen Oliver Michael Privitera Rodney Radtke Ann-Kathrin Ruppert Thomas Sander Steven Schachter Christoph Schankin Ingrid Scheffer Susanne Schoch Sanjay M Sisodiya Philip Smith Michael Sperling Pasquale Striano Rainer Surges G Neil Thomas Frank Visscher Christopher D Whelan Federico Zara Erin L Heinzen Anthony Marson Felicitas Becker Hans Stroink Fritz Zimprich Thomas Gasser Raphael Gibbs Peter Heutink Maria Martinez Huw R Morris Manu Sharma Mina Ryten Kin Y Mok Sara Pulit Steve Bevan Elizabeth Holliday John Attia Thomas Battey Giorgio Boncoraglio Vincent Thijs Wei-Min Chen Braxton Mitchell Peter Rothwell Pankaj Sharma Cathie Sudlow Astrid Vicente Hugh Markus Christina Kourkoulis Joana Pera Miriam Raffeld Scott Silliman Vesna Boraska Perica Laura M Thornton Laura M Huckins N William Rayner Cathryn M Lewis Monica Gratacos Filip Rybakowski Anna Keski-Rahkonen Anu Raevuori James I Hudson Ted Reichborn-Kjennerud Palmiero Monteleone Andreas Karwautz Katrin Mannik Jessica H Baker Julie K O'Toole Sara E Trace Oliver S P Davis Sietske G Helder Stefan Ehrlich Beate Herpertz-Dahlmann Unna N Danner Annemarie A van Elburg Maurizio Clementi Monica Forzan Elisa Docampo Jolanta Lissowska Joanna Hauser Alfonso Tortorella Mario Maj Fragiskos Gonidakis Konstantinos Tziouvas Hana Papezova Zeynep Yilmaz Gudrun Wagner Sarah Cohen-Woods Stefan Herms Antonio Julià Raquel Rabionet Danielle M Dick Samuli Ripatti Ole A Andreassen Thomas Espeseth Astri J Lundervold Vidar M Steen Dalila Pinto Stephen W Scherer Harald Aschauer Alexandra Schosser Lars Alfredsson Leonid Padyukov Katherine A Halmi James Mitchell Michael Strober Andrew W Bergen Walter Kaye Jin Peng Szatkiewicz Bru Cormand Josep Antoni Ramos-Quiroga Cristina Sánchez-Mora Marta Ribasés Miguel Casas Amaia Hervas Maria Jesús Arranz Jan Haavik Tetyana Zayats Stefan Johansson Nigel Williams Astrid Dempfle Aribert Rothenberger Jonna Kuntsi Robert D Oades Tobias Banaschewski Barbara Franke Jan K Buitelaar Alejandro Arias Vasquez Alysa E Doyle Andreas Reif Klaus-Peter Lesch Christine Freitag Olga Rivero Haukur Palmason Marcel Romanos Kate Langley Marcella Rietschel Stephanie H Witt Soeren Dalsgaard Anders D Børglum Irwin Waldman Beth Wilmot Nikolas Molly Claiton H D Bau Jennifer Crosbie Russell Schachar Sandra K Loo James J McGough Eugenio H Grevet Sarah E Medland Elise Robinson Lauren A Weiss Elena Bacchelli Anthony Bailey Vanessa Bal Agatino Battaglia Catalina Betancur Patrick Bolton Rita Cantor Patrícia Celestino-Soper Geraldine Dawson Silvia De Rubeis Frederico Duque Andrew Green Sabine M Klauck Marion Leboyer Pat Levitt Elena Maestrini Shrikant Mane Daniel Moreno- De-Luca Jeremy Parr Regina Regan Abraham Reichenberg Sven Sandin Jacob Vorstman Thomas Wassink Ellen Wijsman Edwin Cook Susan Santangelo Richard Delorme Bernadette Rogé Tiago Magalhaes Dan Arking Thomas G Schulze Robert C Thompson Jana Strohmaier Keith Matthews Ingrid Melle Derek Morris Douglas Blackwood Andrew McIntosh Sarah E Bergen Martin Schalling Stéphane Jamain Anna Maaser Sascha B Fischer Céline S Reinbold Janice M Fullerton José Guzman-Parra Fermin Mayoral Peter R Schofield Sven Cichon Thomas W Mühleisen Franziska Degenhardt Johannes Schumacher Michael Bauer Philip B Mitchell Elliot S Gershon John Rice James B Potash Peter P Zandi Nick Craddock I Nicol Ferrier Martin Alda Guy A Rouleau Gustavo Turecki Roel Ophoff Carlos Pato Adebayo Anjorin Eli Stahl Markus Leber Piotr M Czerski Cristiana Cruceanu Ian R Jones Danielle Posthuma Till F M Andlauer Andreas J Forstner Fabian Streit Bernhard T Baune Tracy Air Grant Sinnamon Naomi R Wray Donald J MacIntyre David Porteous Georg Homuth Margarita Rivera Jakob Grove Christel M Middeldorp Ian Hickie Michele Pergadia Divya Mehta Johannes H Smit Rick Jansen Eco de Geus Erin Dunn Qingqin S Li Matthias Nauck Robert A Schoevers Aartjan Tf Beekman James A Knowles Alexander Viktorin Paul Arnold Cathy L Barr Gabriel Bedoya-Berrio O Joseph Bienvenu Helena Brentani Christie Burton Beatriz Camarena Carolina Cappi Danielle Cath Maria Cavallini Daniele Cusi Sabrina Darrow Damiaan Denys Eske M Derks Andrea Dietrich Thomas Fernandez Martijn Figee Nelson Freimer Gloria Gerber Marco Grados Erica Greenberg Gregory L Hanna Andreas Hartmann Matthew E Hirschtritt Pieter J Hoekstra Alden Huang Chaim Huyser Cornelia Illmann Michael Jenike Samuel Kuperman Bennett Leventhal Christine Lochner Gholson J Lyon Fabio Macciardi Marcos Madruga-Garrido Irene A Malaty Athanasios Maras Lauren McGrath Eurípedes C Miguel Pablo Mir Gerald Nestadt Humberto Nicolini Michael S Okun Andrew Pakstis Peristera Paschou John Piacentini Christopher Pittenger Kerstin Plessen Vasily Ramensky Eliana M Ramos Victor Reus Margaret A Richter Mark A Riddle Mary M Robertson Veit Roessner Maria Rosário Jack F Samuels Paul Sandor Dan J Stein Fotis Tsetsos Filip Van Nieuwerburgh Sarah Weatherall Jens R Wendland Tomasz Wolanczyk Yulia Worbe Gwyneth Zai Fernando S Goes Nicole McLaughlin Paul S Nestadt Hans-Jorgen Grabe Christel Depienne Anuar Konkashbaev Nuria Lanzagorta Ana Valencia-Duarte Elvira Bramon Nancy Buccola Wiepke Cahn Murray Cairns Siow A Chong David Cohen Benedicto Crespo-Facorro James Crowley Michael Davidson Lynn DeLisi Timothy Dinan Gary Donohoe Elodie Drapeau Jubao Duan Lieuwe Haan David Hougaard Sena Karachanak-Yankova Andrey Khrunin Janis Klovins Vaidutis Kučinskas Jimmy Lee Chee Keong Svetlana Limborska Carmel Loughland Jouko Lönnqvist Brion Maher Manuel Mattheisen Colm McDonald Kieran C Murphy Igor Nenadic Jim van Os Christos Pantelis Michele Pato Tracey Petryshen Digby Quested Panos Roussos Alan R Sanders Ulrich Schall Sibylle G Schwab Kang Sim Hon-Cheong So Elisabeth Stögmann Mythily Subramaniam Draga Toncheva John Waddington James Walters Mark Weiser Wei Cheng Robert Cloninger David Curtis Pablo V Gejman Frans Henskens Morten Mattingsdal Sang-Yun Oh Rodney Scott Bradley Webb Gerome Breen Claire Churchhouse Cynthia M Bulik Mark Daly Martin Dichgans Stephen V Faraone Rita Guerreiro Peter Holmans Kenneth S Kendler Bobby Koeleman Carol A Mathews Alkes Price Jeremiah Scharf Pamela Sklar Julie Williams Nicholas W Wood Chris Cotsapas Aarno Palotie Jordan W Smoller Patrick Sullivan Jonathan Rosand Aiden Corvin Benjamin M Neale Jonathan M Schott Richard Anney Josephine Elia Maria Grigoroiu-Serbanescu Howard J Edenberg Robin Murray

Science 2018 06;360(6395)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1126/science.aap8757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097237PMC
June 2018

Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry.

Nat Neurosci 2017 Oct 14;20(10):1342-1349. Epub 2017 Aug 14.

Department of Psychiatry, University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1038/nn.4618DOI Listing
October 2017

Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis.

Early Interv Psychiatry 2017 08 23;11(4):342-345. Epub 2015 Nov 23.

Department of Psychiatry, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/eip.12298DOI Listing
August 2017

Sustainability of treatment effect of a 3-year early intervention programme for first-episode psychosis.

Br J Psychiatry 2017 07 6;211(1):37-44. Epub 2017 Apr 6.

Wing Chung Chang, MRCPsych, FHKCPsych, Department of Psychiatry, Queen Mary Hospital and State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong; Vivian Wing Yan Kwong, MPsyMed, Emily Sin Kei Lau, MSocSc(CP), Department of Psychiatry, Queen Mary Hospital, Hong Kong; Hon Cheong So, MBBS, PhD, School of Biomedical Sciences, the Chinese University of Hong Kong, Hong Kong; Corine Sau Man Wong MsocSc, Gloria Hoi Kei Chan, MSSc(CP), Olivia Tsz Ting Jim, BSocSc, Christy Lai Ming Hui, PhD, Department of Psychiatry, Queen Mary Hospital, Hong Kong; Sherry Kit Wa Chan, MRCPsych, FHKCPsych, Department of Psychiatry, Queen Mary Hospital and State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong Hong Kong; Edwin Ho Ming Lee, MRCPsych, FHKCPsych, Department of Psychiatry, Queen Mary Hospital, Hong Kong; Eric Yu Hai Chen, MD, Department of Psychiatry, Queen Mary Hospital and State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1192/bjp.bp.117.198929DOI Listing
July 2017

Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits.

Bioinformatics 2017 03;33(6):886-892

Department of Psychiatry, University of Hong Kong, PokFuLam, Hong Kong.

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http://dx.doi.org/10.1093/bioinformatics/btw745DOI Listing
March 2017

Improving polygenic risk prediction from summary statistics by an empirical Bayes approach.

Sci Rep 2017 02 1;7:41262. Epub 2017 Feb 1.

Department of Psychiatry, University of Hong Kong, PokFuLam, Hong Kong.

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http://www.nature.com/articles/srep41262
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http://dx.doi.org/10.1038/srep41262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286518PMC
February 2017

Admission Rates and Psychiatric Beds in Hong Kong, 1999-2014: A Population-Based Study.

Psychiatr Serv 2016 05;67(5):579

Dr. Lee and Dr. Chen are with the Department of Psychiatry, University of Hong Kong, Hong Kong, China (e-mail: ). Dr. So is with the School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1176/appi.ps.201600026DOI Listing
May 2016

Common variants on Xq28 conferring risk of schizophrenia in Han Chinese.

Schizophr Bull 2014 Jul 16;40(4):777-86. Epub 2013 Sep 16.

Department of Psychiatry, The University of Hong Kong, Hong Kong, China; Centre for Genomic Sciences, The University of Hong Kong, Hong Kong, China; State Key Laboratory in Brain and Cognitive Sciences, The University of Hong Kong, Hong King, China;

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http://dx.doi.org/10.1093/schbul/sbt104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059435PMC
July 2014

Robust association tests under different genetic models, allowing for binary or quantitative traits and covariates.

Behav Genet 2011 Sep 9;41(5):768-75. Epub 2011 Feb 9.

Department of Psychiatry, 10/F Laboratory Block, LKS Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://link.springer.com/10.1007/s10519-011-9450-9
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http://dx.doi.org/10.1007/s10519-011-9450-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162964PMC
September 2011

Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study.

Genet Epidemiol 2011 Sep 26;35(6):447-56. Epub 2011 May 26.

Department of Psychiatry, LKS Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/gepi.20593DOI Listing
September 2011

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases.

Genet Epidemiol 2011 Jul 3;35(5):310-7. Epub 2011 Mar 3.

Department of Psychiatry, University of Hong Kong, Hong Kong SAR, China.

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http://doi.wiley.com/10.1002/gepi.20579
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http://dx.doi.org/10.1002/gepi.20579DOI Listing
July 2011

Effect size measures in genetic association studies and age-conditional risk prediction.

Hum Hered 2010 13;70(3):205-18. Epub 2010 Sep 13.

Department of Psychiatry, University of Hong Kong, Hong Kong, SAR, China.

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https://www.karger.com/Article/FullText/319192
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http://dx.doi.org/10.1159/000319192DOI Listing
January 2011

Multiple testing and power calculations in genetic association studies.

Cold Spring Harb Protoc 2011 Jan 1;2011(1):pdb.top95. Epub 2011 Jan 1.

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http://dx.doi.org/10.1101/pdb.top95DOI Listing
January 2011

A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained.

PLoS Genet 2010 Dec 2;6(12):e1001230. Epub 2010 Dec 2.

Department of Psychiatry, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1371/journal.pgen.1001230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996330PMC
December 2010

Genetics of schizophrenia spectrum disorders: looking back and peering ahead.

Ann Acad Med Singapore 2009 May;38(5):436-4

Department of Psychiatry, the University of Hong Kong, LKS Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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May 2009

An association study of RGS4 polymorphisms with clinical phenotypes of schizophrenia in a Chinese population.

Am J Med Genet B Neuropsychiatr Genet 2008 Jan;147B(1):77-85

Department of Psychiatry, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1002/ajmg.b.30577DOI Listing
January 2008