Publications Authored by Holger Wagner

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood.

Clin Epigenetics 2019 Nov 27;11(1):164. Epub 2019 Nov 27.

School for Mental Health and Neuroscience (MHeNS), Department of Psychiatry and Neuropsychology, Maastricht University, P.O. Box 616, 6200, MD, Maastricht, the Netherlands.

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http://dx.doi.org/10.1186/s13148-019-0755-5	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880587	PMC

November 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:

Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2019 May 1;10(1):2068. Epub 2019 May 1.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-019-10160-w	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494826	PMC

May 2019

Reply: Biallelic POLR3A variants confirmed as a frequent cause of hereditary ataxia and spastic paraparesis.

Authors:

Martina Minnerop Delia Kurzwelly Holger Wagner Rebecca Schüle Alfredo Ramirez

Brain 2019 04;142(4):e13

Division for Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Medical Faculty, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1093/brain/awz042	DOI Listing

April 2019

Exploring Genetic Associations of Alzheimer's Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes.

Front Aging Neurosci 2018 30;10:340. Epub 2018 Oct 30.

Research Center and Memory Clinic, Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.

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http://dx.doi.org/10.3389/fnagi.2018.00340	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218590	PMC

October 2018

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry.

Authors:

Piotr Lewczuk Peter Riederer Sid E O'Bryant Marcel M Verbeek Bruno Dubois Pieter Jelle Visser Kurt A Jellinger Sebastiaan Engelborghs Alfredo Ramirez Lucilla Parnetti Clifford R Jack Charlotte E Teunissen Harald Hampel Alberto Lleó Frank Jessen Lidia Glodzik Mony J de Leon Anne M Fagan José Luis Molinuevo Willemijn J Jansen Bengt Winblad Leslie M Shaw Ulf Andreasson Markus Otto Brit Mollenhauer Jens Wiltfang Martin R Turner Inga Zerr Ron Handels Alexander G Thompson Gunilla Johansson Natalia Ermann John Q Trojanowski Ilker Karaca Holger Wagner Patrick Oeckl Linda van Waalwijk van Doorn Maria Bjerke Dimitrios Kapogiannis H Bea Kuiperij Lucia Farotti Yi Li Brian A Gordon Stéphane Epelbaum Stephanie J B Vos Catharina J M Klijn William E Van Nostrand Carolina Minguillon Matthias Schmitz Carla Gallo Andrea Lopez Mato Florence Thibaut Simone Lista Daniel Alcolea Henrik Zetterberg Kaj Blennow Johannes Kornhuber

World J Biol Psychiatry 2018 06 27;19(4):244-328. Epub 2017 Oct 27.

a Department of Psychiatry and Psychotherapy , Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg , Erlangen , Germany.

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http://dx.doi.org/10.1080/15622975.2017.1375556	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916324	PMC

June 2018

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies.

Alzheimers Dement 2018 06 6;14(6):707-722. Epub 2018 Jan 6.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Translational Epidemiology, Faculty Science, Leiden University, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.11.012	DOI Listing

June 2018

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:

Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2018 05 29;9(1):2098. Epub 2018 May 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-018-04362-x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974083	PMC

May 2018

Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia.

Authors:

Martina Minnerop Delia Kurzwelly Holger Wagner Anne S Soehn Jennifer Reichbauer Feifei Tao Tim W Rattay Michael Peitz Kristina Rehbach Alejandro Giorgetti Angela Pyle Holger Thiele Janine Altmüller Dagmar Timmann Ilker Karaca Martina Lennarz Jonathan Baets Holger Hengel Matthis Synofzik Burcu Atasu Shawna Feely Marina Kennerson Claudia Stendel Tobias Lindig Michael A Gonzalez Rüdiger Stirnberg Marc Sturm Sandra Roeske Johanna Jung Peter Bauer Ebba Lohmann Stefan Herms Stefanie Heilmann-Heimbach Garth Nicholson Muhammad Mahanjah Rajech Sharkia Paolo Carloni Oliver Brüstle Thomas Klopstock Katherine D Mathews Michael E Shy Peter de Jonghe Patrick F Chinnery Rita Horvath Jürgen Kohlhase Ina Schmitt Michael Wolf Susanne Greschus Katrin Amunts Wolfgang Maier Ludger Schöls Peter Nürnberg Stephan Zuchner Thomas Klockgether Alfredo Ramirez Rebecca Schüle

Brain 2017 06;140(6):1561-1578

Center for Neurology and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1093/brain/awx095	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402316	PMC

June 2017

No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment.

Epigenomics 2016 05 19;8(5):593-8. Epub 2016 Apr 19.

Department of Psychiatry & Psychotherapy, University of Bonn, 53127 Bonn, Germany.

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http://dx.doi.org/10.2217/epi-2015-0014	DOI Listing

May 2016

PLD3 in non-familial Alzheimer's disease.

Nature 2015 Apr;520(7545):E3-5

1] Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany [2] Department of Psychiatry and Psychotherapy, University of Bonn, 53127 Bonn, Germany.

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http://dx.doi.org/10.1038/nature14039	DOI Listing

April 2015

Potent cholesteryl ester transfer protein inhibitors of reduced lipophilicity: 1,1'-spiro-substituted hexahydrofuroquinoline derivatives.

Authors:

Thomas Trieselmann Holger Wagner Klaus Fuchs Dieter Hamprecht Daniela Berta Paolo Cremonesi Rüdiger Streicher Gerd Luippold Astrid Volz Michael Markert Herbert Nar

J Med Chem 2014 Nov 27;57(21):8766-76. Epub 2014 Oct 27.

Departments of Medicinal Chemistry, §Cardiometabolic Diseases, ⊥Drug Discovery Support, and ∥Lead Identification, Boehringer Ingelheim Pharma GmbH & Co. KG , Birkendorfer Strasse 65, 88397 Biberach an der Riss, Germany.

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