Holger Kalthoff

Holger Kalthoff

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Holger Kalthoff

Publications by authors named "Holger Kalthoff"

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The expression of death receptor systems TRAIL-R1/-R2/-R4, CD95 and TNF-R1 and their cognate ligands in pancreatic ductal adenocarcinoma.

Histol Histopathol 2019 May 24;34(5):491-501. Epub 2018 Oct 24.

Institute for Experimental Cancer Research, Christian-Albrechts-University, Kiel, Germany.

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http://dx.doi.org/10.14670/HH-18-054DOI Listing
May 2019

E2F1 Signalling is Predictive of Chemoresistance and Lymphogenic Metastasis in Penile Cancer: A Pilot Functional Study Reveals New Prognostic Biomarkers.

Eur Urol Focus 2018 07 1;4(4):599-607. Epub 2017 Mar 1.

Institute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Centre, Rostock, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2017.02.009DOI Listing
July 2018

Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC.

BMC Cancer 2018 Jul 31;18(1):777. Epub 2018 Jul 31.

Department of General Surgery, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Arnold-Heller Str. 3, Haus 18, 24105, Kiel, Germany.

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http://dx.doi.org/10.1186/s12885-018-4688-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069838PMC
July 2018

The prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma.

Oncotarget 2017 Feb;8(9):15159-15167

Department of Surgery, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.18632/oncotarget.14768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362475PMC
February 2017

Detection of circulating tumor cells with CK20 RT-PCR is an independent negative prognostic marker in colon cancer patients - a prospective study.

BMC Cancer 2017 01 13;17(1):53. Epub 2017 Jan 13.

Division Molecular Oncology, Institute for Experimental Cancer Research, Cancer Center North, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller Str. 7, 24105, Kiel, Germany.

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http://dx.doi.org/10.1186/s12885-016-3035-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237158PMC
January 2017

Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1.

Cell Signal 2016 11 1;28(11):1652-62. Epub 2016 Aug 1.

Institute for Experimental Cancer Research, University of Kiel, D-24105 Kiel, Germany; Clinic for General Surgery, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Hospital Schleswig-Holstein, Campus Kiel, D-24105 Kiel, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2016.07.016DOI Listing
November 2016

Target Gene Discovery for Novel Therapeutic Agents in Cancer Treatment.

Methods Mol Biol 2016 ;1381:181-200

Institute for Experimental Cancer Research, Section for Molecular Oncology, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Strasse 3, House 17, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/978-1-4939-3204-7_10DOI Listing
October 2016

Influence of mTOR-inhibitors and mycophenolic acid on human cholangiocellular carcinoma and cancer associated fibroblasts.

BMC Cancer 2016 05 20;16:322. Epub 2016 May 20.

Department of General, Visceral-, Thoracic-, Transplantation- and Pediatric Surgery, University Medical Center Schleswig-Holstein (UKSH), Campus Kiel, Arnold-Heller-Strasse 3 (Haus 18), 24105, Kiel, Germany.

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http://dx.doi.org/10.1186/s12885-016-2360-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875636PMC
May 2016

Interleukin-6 trans-signaling increases the expression of carcinoembryonic antigen-related cell adhesion molecules 5 and 6 in colorectal cancer cells.

BMC Cancer 2015 Dec 16;15:975. Epub 2015 Dec 16.

Division of Molecular Oncology, Institute for Experimental Cancer Research, University Hospital Schleswig-Holstein, 24105, Kiel, Germany.

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http://dx.doi.org/10.1186/s12885-015-1950-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682226PMC
December 2015

Cytokeratin 20 positive circulating tumor cells are a marker for response after neoadjuvant chemoradiation but not for prognosis in patients with rectal cancer.

BMC Cancer 2015 Dec 16;15:953. Epub 2015 Dec 16.

Division Molecular Oncology, Institute for Experimental Cancer Research, Cancer Center North, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller Str. 7, 24105, Kiel, Germany.

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http://dx.doi.org/10.1186/s12885-015-1989-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682277PMC
December 2015

Integrins αvβ3 and αvβ5 as prognostic, diagnostic, and therapeutic targets in gastric cancer.

Gastric Cancer 2015 Oct 15;18(4):784-95. Epub 2014 Oct 15.

Department of Pathology, Christian Albrechts University, Arnold-Heller-Str. 3, Haus 14, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s10120-014-0435-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572058PMC
October 2015

Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer.

Int J Cancer 2015 Sep 29;137(5):1035-46. Epub 2015 Jan 29.

Division of Molecular Oncology, Institute for Experimental Cancer Research, CCC-North, University Hospital Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.1002/ijc.29445DOI Listing
September 2015

Molecular Mechanisms by Which a Fucus vesiculosus Extract Mediates Cell Cycle Inhibition and Cell Death in Pancreatic Cancer Cells.

Mar Drugs 2015 Jul 20;13(7):4470-91. Epub 2015 Jul 20.

Division of Molecular Oncology, Institute for Experimental Cancer Research, Medical Faculty, CAU, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.

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http://dx.doi.org/10.3390/md13074470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515628PMC
July 2015

Profile of serum factors and disseminated tumor cells before and after radiofrequency ablation compared to resection of colorectal liver metastases - a pilot study.

Anticancer Res 2015 May;35(5):2961-7

Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.

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May 2015

Impact of molecular imaging in preclinical cancer research.

BMC Proc 2013 4;7 Suppl 2:K4. Epub 2013 Apr 4.

Institute for Experimental Cancer Research, Comprehensive Cancer Center North; UKSH-Campus Kiel, Arnold-Heller-Str. 3, 24105 Kiel, Germany.

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http://dx.doi.org/10.1186/1753-6561-7-S2-K4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624122PMC
April 2015

Interleukin-6: a villain in the drama of pancreatic cancer development and progression.

Hepatobiliary Pancreat Dis Int 2014 Aug;13(4):371-80

Division of Molecular Oncology, Institute for Experimental Cancer Research, CCC-North, University of Kiel, D-24105 Kiel, Germany.

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August 2014

Integrins and their ligands are expressed in non-small cell lung cancer but not correlated with parameters of disease progression.

Virchows Arch 2014 Jan 26;464(1):69-78. Epub 2013 Nov 26.

Department of Pathology, Christian-Albrechts-University, Arnold-Heller-Str. 3, Haus 14, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s00428-013-1506-1DOI Listing
January 2014

Validation and comparison of anti-αvβ3 and anti-αvβ5 rabbit monoclonal versus murine monoclonal antibodies in four different tumor entities.

Appl Immunohistochem Mol Morphol 2013 Dec;21(6):553-60

Departments of *Pathology †Experimental Cancer Research, Christian-Albrechts-University, Kiel ‡Department of Biochemistry and Cellular Pharmacology, Oncology Platform, Merck KGaA, Darmstadt, Germany.

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http://dx.doi.org/10.1097/PAI.0b013e318284a03aDOI Listing
December 2013

The diversity between pancreatic head and body/tail cancers: clinical parameters and in vitro models.

Hepatobiliary Pancreat Dis Int 2013 Oct;12(5):480-7

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine; Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health, Hangzhou, 310003, China.

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October 2013

Association study identifying polymorphisms in CD47 and other extracellular matrix pathway genes as putative prognostic markers for colorectal cancer.

Int J Colorectal Dis 2013 Feb 28;28(2):173-81. Epub 2012 Jul 28.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00384-012-1541-4DOI Listing
February 2013

TRAIL-induced expression of uPA and IL-8 strongly enhanced by overexpression of TRAF2 and Bcl-xL in pancreatic ductal adenocarcinoma cells.

Hepatobiliary Pancreat Dis Int 2013 Feb;12(1):94-8

Department of Oncology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

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February 2013

Disseminated tumor cells in the bone marrow negatively influence survival after resection of colorectal liver metastases.

Ann Surg Oncol 2012 Aug 7;19(8):2539-46. Epub 2012 Mar 7.

Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.1245/s10434-012-2291-9DOI Listing
August 2012

Silvalactam, a 24-membered macrolactam antibiotic produced by Streptomyces sp. Tü 6392*.

J Antibiot (Tokyo) 2012 Jul 9;65(7):369-72. Epub 2012 May 9.

Mikrobiologisches Institut, Universität Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1038/ja.2012.33DOI Listing
July 2012

Establishment and characterization of primary cell lines of squamous cell carcinoma of the penis and its metastasis.

J Urol 2012 Jun 13;187(6):2236-42. Epub 2012 Apr 13.

Department of Urology and Pediatric Urology, University Hospital Schleswig Holstein, Kiel, Germany.

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http://dx.doi.org/10.1016/j.juro.2012.01.035DOI Listing
June 2012

Characterisation of FAP-1 expression and CD95 mediated apoptosis in the A818-6 pancreatic adenocarcinoma differentiation system.

Differentiation 2012 Mar 21;83(3):148-57. Epub 2011 Dec 21.

Institute for Experimental Cancer Research, Division Molecular Oncology, University Hospital Schleswig-Holstein Campus Kiel, Germany.

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http://dx.doi.org/10.1016/j.diff.2011.11.013DOI Listing
March 2012

Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent.

Carcinogenesis 2012 Jan 17;33(1):84-93. Epub 2011 Nov 17.

Department of Internal Medicine I, Laboratory of Molecular Gastroenterology and Hepatology, UKSH-Campus Kiel, 24105 Kiel, Germany.

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http://carcin.oxfordjournals.org/content/33/1/84.full.pdf
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http://www.carcin.oxfordjournals.org/cgi/doi/10.1093/carcin/
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http://dx.doi.org/10.1093/carcin/bgr262DOI Listing
January 2012

Near-infrared molecular imaging of tumors via chemokine receptors CXCR4 and CXCR7.

Clin Exp Metastasis 2011 Dec 7;28(8):713-20. Epub 2011 Jul 7.

Department of Anatomy, University of Kiel, Olshausenstraße 40, 24098 Kiel, Germany.

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http://dx.doi.org/10.1007/s10585-011-9403-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213350PMC
December 2011

Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma.

Eur J Cell Biol 2011 Jun-Jul;90(6-7):450-5. Epub 2010 Dec 3.

Sektion für Molekulare Onkologie, Institut für Experimentelle Tumorforschung, Krebszentrum Nord - CCC, Universitätsklinikum Schleswig-Holstein, Campus Kiel, 24105 Kiel, Arnold-Heller-Str. 3, Haus 18, Germany.

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http://dx.doi.org/10.1016/j.ejcb.2010.10.008DOI Listing
September 2011

Emerging therapeutic targets and agents for pancreatic cancer therapy--where are we and where we have to go?

Anticancer Agents Med Chem 2011 Jun;11(5):408-10

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June 2011

Assessment of anti-inflammatory tumor treatment efficacy by longitudinal monitoring employing sonographic micro morphology in a preclinical mouse model.

BMC Med Imaging 2011 Jun 23;11:15. Epub 2011 Jun 23.

Division of Molecular Oncology, Institute for Experimental Cancer Research, Comprehensive Cancer Center North, University Hospital Schleswig-Holstein, Campus Kiel, Germany.

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http://dx.doi.org/10.1186/1471-2342-11-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143928PMC
June 2011

Sunitinib (SU11248) inhibits growth of human ovarian cancer in xenografted mice.

Anticancer Res 2010 Sep;30(9):3355-60

Department of Gynecology and Obstetrics, University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany.

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September 2010

Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway.

J Immunol 2010 Aug 7;185(3):1593-605. Epub 2010 Jul 7.

Division of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.4049/jimmunol.0903555DOI Listing
August 2010

TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5.

J Mol Med (Berl) 2010 Jul 31;88(7):729-40. Epub 2010 Mar 31.

Division of Molecular Oncology, Institute of Experimental Cancer Research, Comprehensive Cancer Center North, UK S-H, Arnold-Heller Str. 3, Haus 17, 24 105 Kiel, Germany.

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http://dx.doi.org/10.1007/s00109-010-0619-0DOI Listing
July 2010

Target gene discovery for novel therapeutic agents in cancer treatment.

Methods Mol Biol 2010 ;576:427-45

Clinic for General Surgery and Thoracic Surgery, Division Molecular Oncology, University Hospital of Schleswig, Kiel, Germany.

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http://dx.doi.org/10.1007/978-1-59745-545-9_22DOI Listing
January 2010

Lymphatic spread in squamous cell carcinoma of the penis is independent of elevated lymph vessel density.

BJU Int 2009 Jun 10;103(12):1655-9; discussion 1659. Epub 2009 Feb 10.

Department of Urology and Paediatric Urology, University Hospitsl Schleswig Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1111/j.1464-410X.2009.08365.xDOI Listing
June 2009

Systematic identification and validation of candidate genes for detection of circulating tumor cells in peripheral blood specimens of colorectal cancer patients.

Int J Oncol 2008 Nov;33(5):1001-10

Institute for Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, 68167 Mannheim, Germany.

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November 2008

Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases.

Int J Cancer 2008 Oct;123(8):1751-60

Clinic of General Internal Medicine, Laboratory of Molecular Gastroenterology and Hepatology, UKSH-Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1002/ijc.23703DOI Listing
October 2008

Dexamethasone reduces tumor recurrence and metastasis after pancreatic tumor resection in SCID mice.

Cancer Biol Ther 2008 Jul 14;7(7):1044-50. Epub 2008 Apr 14.

Division of Molecular Oncology, Department of General Surgery and Thoracic Surgery, University Hospital of Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.4161/cbt.7.7.6099DOI Listing
July 2008

Prowling wolves in sheep's clothing: the search for tumor stem cells.

Biol Chem 2008 Jul;389(7):799-811

Department of General and Thoracic Surgery, Division of Molecular Oncology, University Hospital Schleswig-Holstein, Campus Kiel, Arnold Heller Str. 7, Kiel, Germany.

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http://dx.doi.org/10.1515/BC.2008.094DOI Listing
July 2008

The potential molecular mechanism of overexpression of uPA, IL-8, MMP-7 and MMP-9 induced by TRAIL in pancreatic cancer cell.

Hepatobiliary Pancreat Dis Int 2008 Apr;7(2):201-9

Department of Oncology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

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April 2008

Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis.

Cancer Res 2008 Mar;68(5):1443-50

Division of Molecular Oncology, Department of General Surgery and Thoracic Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5704DOI Listing
March 2008

Foxp3 expression in pancreatic carcinoma cells as a novel mechanism of immune evasion in cancer.

Cancer Res 2007 Sep;67(17):8344-50

Division Molecular Oncology, Department for General Surgery, Institute of Immunology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3304DOI Listing
September 2007

Establishment of a novel orthotopic xenograft model of human gallbladder carcinoma.

Clin Exp Metastasis 2007 4;24(3):141-8. Epub 2007 Apr 4.

Department of General Surgery and Thoracic Surgery, Schleswig-Holstein University Hospitals, Campus Kiel, Arnold-Heller-Strasse 7, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s10585-007-9058-xDOI Listing
August 2007

Superiority of extended neoadjuvant chemotherapy with gemcitabine in pancreatic cancer: a comparative analysis in a clinically adapted orthotopic xenotransplantation model in SCID beige mice.

Cancer Biol Ther 2007 Aug 10;6(8):1227-32. Epub 2007 May 10.

Department of General Surgery and Thoracic Surgery, University Hospital of Schleswig-Holstein Campus, Kiel, Germany.

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http://dx.doi.org/10.4161/cbt.6.8.4414DOI Listing
August 2007

Role of caspases in CD95L- and TRAIL-induced non-apoptotic signalling in pancreatic tumour cells.

Cell Signal 2007 Jun 3;19(6):1172-84. Epub 2007 Jan 3.

Department of Molecular Internal Medicine, Medical Clinic and Polyclinic II, University of Wuerzburg, and Division of Molecular Oncology, Clinic for General Surgery and Thoracic Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.1016/j.cellsig.2006.12.008DOI Listing
June 2007

The role of protein kinases in pancreatic carcinogenesis.

Clin Chim Acta 2007 May 21;381(1):56-62. Epub 2007 Feb 21.

University Hospital of Schlewig-Holstein, Campus Kiel, Clinic for General Surgery and Thoracic Surgery, Division of Molecular Oncology, Arnold-Heller-Strasse 7, 24105 Kiel, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S000989810700093
Publisher Site
http://dx.doi.org/10.1016/j.cca.2007.02.024DOI Listing
May 2007

Antitumor activity of ALK1 in pancreatic carcinoma cells.

Int J Cancer 2007 Apr;120(8):1641-51

Department of General Surgery and Thoracic Surgery, UKSH, Campus Kiel, Arnold-Heller-Str. 7, 24105 Kiel, Germany.

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http://dx.doi.org/10.1002/ijc.22393DOI Listing
April 2007

Detection of tumor stem cell markers in pancreatic carcinoma cell lines.

Hepatobiliary Pancreat Dis Int 2007 Feb;6(1):92-7

Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Arnold Heller Str. 7, 24 105 Kiel, Germany.

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February 2007

Combination phenylbutyrate/gemcitabine therapy effectively inhibits in vitro and in vivo growth of NSCLC by intrinsic apoptotic pathways.

J Carcinog 2006 Nov 23;5:25. Epub 2006 Nov 23.

Hospital for General and Thoracic Surgery, Schleswig-Holstein University Hospitals, Campus Kiel, Arnold-Heller-Str 7, Kiel, Germany.

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http://dx.doi.org/10.1186/1477-3163-5-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665446PMC
November 2006

Stable expression of temperature-sensitive p53: a suitable model to study wild-type p53 function in pancreatic carcinoma cells.

Oncol Rep 2006 Sep;16(3):575-9

Department of General and Thoracic Surgery, Research Unit Molecular Oncology, University Hospital Schleswig-Holstein, D-24105 Kiel, Germany.

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September 2006

Adjuvant treatment of pancreatic carcinoma in a clinically adapted mouse resection model.

Pancreatology 2006 15;6(3):240-7. Epub 2006 Mar 15.

Clinic for General Surgery and Thoracic Surgery, University Hospital of Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.1159/000092027DOI Listing
August 2006

Pancreatic cancer--are there new treatment options?

Adv Exp Med Biol 2006 ;574:107-10

Department of General Surgery and Thoracic Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Germany.

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http://dx.doi.org/10.1007/0-387-29512-7_12DOI Listing
August 2006

A modified random oligonucleotide-based combination therapy for adjuvant treatment of pancreatic ductal adenocarcinoma.

Int J Oncol 2006 May;28(5):1105-12

Department of General Surgery and Thoracic Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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May 2006

Detection of tumor cell dissemination in pancreatic ductal carcinoma patients by CK 20 RT-PCR indicates poor survival.

J Cancer Res Clin Oncol 2005 Oct 1;131(10):669-76. Epub 2005 Sep 1.

Section Molecular Oncology, Department for General Surgery and Thoracic Surgery, University Clinic Schleswig-Holstein, Campus Kiel, Germany.

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http://dx.doi.org/10.1007/s00432-005-0008-1DOI Listing
October 2005

Detection and clinical implications of minimal residual disease in gastro-intestinal cancer.

Langenbecks Arch Surg 2005 Sep 1;390(5):430-41. Epub 2005 Jul 1.

Department of General and Thoracic Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Arnold-Heller-Strasse 7, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s00423-005-0558-3DOI Listing
September 2005

Adhesion and Rac1-dependent regulation of biglycan gene expression by transforming growth factor-beta. Evidence for oxidative signaling through NADPH oxidase.

J Biol Chem 2005 Sep 28;280(39):33190-9. Epub 2005 Jul 28.

Department of General Surgery and Thoracic Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Strasse 7, Kiel 24105, Germany.

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http://dx.doi.org/10.1074/jbc.M504249200DOI Listing
September 2005

Gemcitabine-mediated apoptosis is associated with increased CD95 surface expression but is not inhibited by DN-FADD in Colo357 pancreatic cancer cells.

Cancer Lett 2005 Sep;227(2):193-200

Clinic for General and Thoracic Surgery, Molecular Oncology Research Group, University of Kiel, Arnold-Heller-Str. 7, 24105 Kiel, Germany.

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http://dx.doi.org/10.1016/j.canlet.2005.01.016DOI Listing
September 2005

Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes.

Oncogene 2005 Jul;24(32):5079-88

Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany.

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http://dx.doi.org/10.1038/sj.onc.1208696DOI Listing
July 2005

CD95 and TRAF2 promote invasiveness of pancreatic cancer cells.

FASEB J 2005 Apr 24;19(6):620-2. Epub 2005 Jan 24.

Molecular Oncology Unit, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1096/fj.04-2984fjeDOI Listing
April 2005